Basic Information

Insect: Drosophila obscura
Gene Symbol: -
Assembly: GCA_018151105.1
Location: NW:11655395-11658804[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 2.6e-07 1.6e-05 24.8 1.1 1 23 215 238 215 238 0.97

2 17 0.0028 0.17 12.1 0.4 1 23 245 267 245 267 0.98

3 17 0.2 12 6.3 0.1 2 23 299 320 298 320 0.94

4 17 0.00024 0.015 15.5 2.8 1 23 408 431 408 431 0.97

5 17 0.25 15 6.0 0.5 1 19 438 456 438 459 0.94

6 17 0.023 1.4 9.2 5.2 1 23 468 490 468 490 0.95

7 17 1.9e-05 0.0012 18.9 0.7 1 23 497 520 497 520 0.97

8 17 7.9e-05 0.0048 17.0 1.2 2 23 528 549 527 549 0.96

9 17 0.002 0.12 12.5 0.1 2 21 576 595 575 596 0.94

10 17 0.0042 0.26 11.5 2.7 1 23 644 667 644 667 0.98

11 17 0.1 6.1 7.2 1.9 1 23 704 727 704 727 0.95

12 17 0.00012 0.0073 16.4 1.6 2 23 756 778 755 778 0.95

13 17 0.00011 0.0065 16.6 0.2 1 23 792 814 792 814 0.95

14 17 0.00012 0.0076 16.4 1.1 1 23 820 842 820 842 0.99

15 17 3.1e-07 1.9e-05 24.5 2.3 1 23 848 870 848 870 0.98

16 17 3.5e-05 0.0021 18.1 3.8 1 23 876 898 876 898 0.97

17 17 0.00044 0.027 14.6 0.4 1 22 904 925 904 928 0.90

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	2.6e-07	1.6e-05	24.8	1.1	1	23	215	238	215	238	0.97
2	17	0.0028	0.17	12.1	0.4	1	23	245	267	245	267	0.98
3	17	0.2	12	6.3	0.1	2	23	299	320	298	320	0.94
4	17	0.00024	0.015	15.5	2.8	1	23	408	431	408	431	0.97
5	17	0.25	15	6.0	0.5	1	19	438	456	438	459	0.94
6	17	0.023	1.4	9.2	5.2	1	23	468	490	468	490	0.95
7	17	1.9e-05	0.0012	18.9	0.7	1	23	497	520	497	520	0.97
8	17	7.9e-05	0.0048	17.0	1.2	2	23	528	549	527	549	0.96
9	17	0.002	0.12	12.5	0.1	2	21	576	595	575	596	0.94
10	17	0.0042	0.26	11.5	2.7	1	23	644	667	644	667	0.98
11	17	0.1	6.1	7.2	1.9	1	23	704	727	704	727	0.95
12	17	0.00012	0.0073	16.4	1.6	2	23	756	778	755	778	0.95
13	17	0.00011	0.0065	16.6	0.2	1	23	792	814	792	814	0.95
14	17	0.00012	0.0076	16.4	1.1	1	23	820	842	820	842	0.99
15	17	3.1e-07	1.9e-05	24.5	2.3	1	23	848	870	848	870	0.98
16	17	3.5e-05	0.0021	18.1	3.8	1	23	876	898	876	898	0.97
17	17	0.00044	0.027	14.6	0.4	1	22	904	925	904	928	0.90

Sequence Information

Coding Sequence: ATGAAGCTGCCGGTAATTTGTCGGACATGTGATGCGACAGATGCCGATAATCTTTTGAAACTGGCCACTCCCACGAAGAAGTACCCAGACAAGTTGCTTGCGGACATCTTGAGCGAACTCACAGCCATTAATATTAATCTGGACACATCTTCTAACCAGAAGCTTCCACAGTGTTTGTGTAGCAGTTGCACAAAGAAATTGATTGGTGCCTATTGCTATGTAAGGCAATGCAAGGCCGCAAATGATCTACTGCTGAAGCACATAAAAAACGGTACTGATTGCTTGCAAGAAACGCCCATGGAGCTATGTGCAGAGCAGCATGTGATGGTAAAACTAGAAACggaggatgaggatggagGGAAAACTGAAACAAACATAAATTGCTCTCGGTTATCTGAAATTGTCCCGGCAGAGAGTCCAGACGAAAAAGATTTCAACAACAAGAAATCTGTTGATCCTCTAATAATGATCGATTCTGTCAAGCAGGAAACAGTGCAGGCCAGGATAGAAAATCATGTAGATTACGAAGCCGTGTCGGACTTTGAGGACGAAGACTCACTGGATAACTTGCCACTGGGACAGCGCATGCTTAAATGGAAGACGGGAAATGGCGATTCCTTGCGAAGTCTGAACCTGTCTCTTTACCAGTGCAATGAATGCCCAAAAAACTTCAAACGAGCCGATTATCTGAAACGACATCGAATCAGGGCTCATAAGCCAGAATCCAGCTGGTTCTCCTGTTCACTTTGCATCCGGAAGTTCAATAGCAGTGAGGCCTTGGAAATGCATCTTAAAGTACATCGAAATCCCAAGCGCTCGGGCAATATAAGTGAGCATAAAAAGGCAAAGTCTGTGGATCTAAATCTATGCAAACCTCATGGATACAAGCTCATCGAATGCATGATCTGTCAGAGTCAGTACAACAAGATTGCGGATCTTCGACGCCATTTGGAGGAGCATCCGGAAATTATTACCTTGGGAGTGCGCCCGAATATGGAACCCAATGAGTTGGCCGAGTTGTTATATCCCGATGCCAAGGATGTAGGCGAGGATCAATTAATTGATATGATTCGCAAAGATTTGGCAGGGGGGATATATCATCGCTTTTATTCAATAACTAATCAGTGTGGTTATGAAATGAACCTGGACAGCTCTGACACTGATAGTGAGCTGGACGAGCCCGAAGATCAACAAAGGAAGCGAAAAACTAGAAAGGCGCATTACAGCTGCGAGCTGTGCCTACAGAGGTTTACCAGGAAGTATCAACTCTACGATCATCAGCGTCAGACGCACAGCTGGTCCGAAGCACCTCATGTTTGCGGCCGATGCGATGGGCGCTTTGTCAGCTTGCAAATGCTAAGGCATCATAATGAGTCGCAGTGCAGAAATTCGCAAAAGCGTTTCCTTTGCCACAAATGCCCACTGCGGTTCCGGTGGAAGCACAACCTGAGAGCACATTTCCGAGAGCACCGAATCACTaatcaaacctttgaatGTTCCGAATGCAAGCGTGTTTTTGACAAGAAAAAATCCCTGACTGTTCATTTACTCAGCGCCCATGCTGAGGAATCGAAGCTCATTCCGTGTCAGTGGTGTACGCGCAAGTTCTATCGGCGTGACTACCTAGTGAAACATCTAAAGCGGCACGGACTCAAGGAGCAGGACATTCCATTGGCCGAGACCCTGATAGCAGCCACATCTAAGCGGAATGGATCCAAGCGCATTACCTGCAAAATTTGCGACCTGCATTTTGACCGCATCATAGATTTGCGTGCCCACATTCAAATGGAACTAAAGCTATCTCTATCGCACCATAGCTACGAGTCCCCGCAAAACTACTCTATAACCAATGAATCCGGCTTCGAGATGCAGCTTGAAGATTCGGAAACAGAGGACGAAATACAGCCTGGGCCCGACAACCATCCTCTCTACGTCTGCGAGCTTTGCAGTGTCCAGTGCAAGCGCAAATTCGAAATGATTCAACATCAACGGACCATGCACCGCTTCGACAAAATGCCTCATGAGTGTGATAAATGCGTTTTTAAGTGTGTTTCCAAGAATATCATGGATCATCATCTTCTATGGCAATGCAGCAGCACAGAGAAGAAGCATTCATGCAGCAAGTGCACCTATAAATTCATGTGGCCTGAGAATCTGGATAAGCACGTGCGCCTCCAGCATAGCGAAGTCTCCGAAATCACCAAAGCAGCCAAGCCGACAAGTGGTCTTGTCGATGATGCCACAGAGGACGGAGTCCAGCTTCTGCAATGCCCGCACTGTGATCGCACCTATCAAATGAAGTCGCGATTGAACAACCACATTCGGGATGTTCATGTAAACGGAGATCGAAAGCGCAAGGATGCGATTAAGAGATTCCTTTGCTCGCTTTGTGGCAGAGAAACGCGgtcggctgctgctctggTTACCCACATGCGACGGCACACCGGCGAGAAGCCCTTTAAATGTGATCTATGTGAAATGGCTTTTCCGAGACACTCGGAGATGGCTTCGCATCGCAGGATGCATACGGGGGAGAAACCATTCCACTGCACAGTTTGTGGCAAGGATTTTGCCCGTTCCGACAAACTGACGCGGCACATGCTCACCCACAGCGGATTGAAACCGCACAAGTGCACGTACTGCGAGAAGAGCTACCGGCAAGCGAAGGATCTGAAGCTCCATTTGCAACAGCACACAGGCGAATGTCCATTTATCTGTGGCACGTGTGGCGAACGATTTATACAGAACATAACTCTGGAGAAGCATCGCCTAATGCGCCGCCATTTCGATTGGAGTTTGCCATAa
Protein Sequence: MKLPVICRTCDATDADNLLKLATPTKKYPDKLLADILSELTAININLDTSSNQKLPQCLCSSCTKKLIGAYCYVRQCKAANDLLLKHIKNGTDCLQETPMELCAEQHVMVKLETEDEDGGKTETNINCSRLSEIVPAESPDEKDFNNKKSVDPLIMIDSVKQETVQARIENHVDYEAVSDFEDEDSLDNLPLGQRMLKWKTGNGDSLRSLNLSLYQCNECPKNFKRADYLKRHRIRAHKPESSWFSCSLCIRKFNSSEALEMHLKVHRNPKRSGNISEHKKAKSVDLNLCKPHGYKLIECMICQSQYNKIADLRRHLEEHPEIITLGVRPNMEPNELAELLYPDAKDVGEDQLIDMIRKDLAGGIYHRFYSITNQCGYEMNLDSSDTDSELDEPEDQQRKRKTRKAHYSCELCLQRFTRKYQLYDHQRQTHSWSEAPHVCGRCDGRFVSLQMLRHHNESQCRNSQKRFLCHKCPLRFRWKHNLRAHFREHRITNQTFECSECKRVFDKKKSLTVHLLSAHAEESKLIPCQWCTRKFYRRDYLVKHLKRHGLKEQDIPLAETLIAATSKRNGSKRITCKICDLHFDRIIDLRAHIQMELKLSLSHHSYESPQNYSITNESGFEMQLEDSETEDEIQPGPDNHPLYVCELCSVQCKRKFEMIQHQRTMHRFDKMPHECDKCVFKCVSKNIMDHHLLWQCSSTEKKHSCSKCTYKFMWPENLDKHVRLQHSEVSEITKAAKPTSGLVDDATEDGVQLLQCPHCDRTYQMKSRLNNHIRDVHVNGDRKRKDAIKRFLCSLCGRETRSAAALVTHMRRHTGEKPFKCDLCEMAFPRHSEMASHRRMHTGEKPFHCTVCGKDFARSDKLTRHMLTHSGLKPHKCTYCEKSYRQAKDLKLHLQQHTGECPFICGTCGERFIQNITLEKHRLMRRHFDWSLP

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00487433;
90% Identity: iTF_00611484;
80% Identity: -