Basic Information

Insect: Drosophila obscura
Gene Symbol: -
Assembly: GCA_018151105.1
Location: NW:5078473-5082358[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 21 0.14 8.5 6.8 0.1 1 20 251 270 251 272 0.93

2 21 0.0074 0.45 10.8 2.5 1 20 279 298 279 301 0.95

3 21 0.0029 0.18 12.1 0.3 1 20 351 370 351 372 0.88

4 21 0.00022 0.014 15.6 3.5 1 23 375 397 375 397 0.97

5 21 0.0054 0.33 11.2 0.7 1 23 403 425 403 425 0.97

6 21 2.8 1.7e+02 2.7 0.1 1 23 431 454 431 454 0.88

7 21 0.00047 0.029 14.5 2.5 1 23 670 692 670 692 0.97

8 21 5.3e-05 0.0032 17.5 5.0 1 23 700 722 700 722 0.97

9 21 0.0051 0.31 11.3 2.8 1 23 728 750 728 750 0.96

10 21 0.0063 0.38 11.0 4.9 1 23 757 779 757 779 0.97

11 21 2.7e-05 0.0016 18.5 2.3 1 23 785 807 785 807 0.96

12 21 8.6e-06 0.00053 20.0 1.4 1 23 813 835 813 835 0.98

13 21 1.6e-05 0.00097 19.2 0.6 1 23 841 863 841 863 0.97

14 21 7.4e-05 0.0045 17.1 2.6 1 23 869 891 869 891 0.96

15 21 0.0016 0.095 12.9 1.9 1 23 898 920 898 920 0.97

16 21 0.00011 0.0064 16.6 3.4 1 23 926 948 926 948 0.98

17 21 6.5e-06 0.0004 20.4 1.2 1 23 954 976 954 976 0.98

18 21 0.0032 0.19 11.9 0.2 1 23 982 1004 982 1004 0.94

19 21 0.0047 0.29 11.4 2.3 1 20 1010 1029 1010 1031 0.94

20 21 0.61 38 4.7 1.1 1 23 1038 1061 1038 1061 0.89

21 21 0.066 4 7.8 0.1 1 21 1064 1084 1064 1085 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	21	0.14	8.5	6.8	0.1	1	20	251	270	251	272	0.93
2	21	0.0074	0.45	10.8	2.5	1	20	279	298	279	301	0.95
3	21	0.0029	0.18	12.1	0.3	1	20	351	370	351	372	0.88
4	21	0.00022	0.014	15.6	3.5	1	23	375	397	375	397	0.97
5	21	0.0054	0.33	11.2	0.7	1	23	403	425	403	425	0.97
6	21	2.8	1.7e+02	2.7	0.1	1	23	431	454	431	454	0.88
7	21	0.00047	0.029	14.5	2.5	1	23	670	692	670	692	0.97
8	21	5.3e-05	0.0032	17.5	5.0	1	23	700	722	700	722	0.97
9	21	0.0051	0.31	11.3	2.8	1	23	728	750	728	750	0.96
10	21	0.0063	0.38	11.0	4.9	1	23	757	779	757	779	0.97
11	21	2.7e-05	0.0016	18.5	2.3	1	23	785	807	785	807	0.96
12	21	8.6e-06	0.00053	20.0	1.4	1	23	813	835	813	835	0.98
13	21	1.6e-05	0.00097	19.2	0.6	1	23	841	863	841	863	0.97
14	21	7.4e-05	0.0045	17.1	2.6	1	23	869	891	869	891	0.96
15	21	0.0016	0.095	12.9	1.9	1	23	898	920	898	920	0.97
16	21	0.00011	0.0064	16.6	3.4	1	23	926	948	926	948	0.98
17	21	6.5e-06	0.0004	20.4	1.2	1	23	954	976	954	976	0.98
18	21	0.0032	0.19	11.9	0.2	1	23	982	1004	982	1004	0.94
19	21	0.0047	0.29	11.4	2.3	1	20	1010	1029	1010	1031	0.94
20	21	0.61	38	4.7	1.1	1	23	1038	1061	1038	1061	0.89
21	21	0.066	4	7.8	0.1	1	21	1064	1084	1064	1085	0.91

Sequence Information

Coding Sequence: ATGTCTCAGTATATATGCCTCTCGTGCATTCAGGCCGCCCAAAATGCATATCGTTTCAAGTTAATATTGGAACAAAGCATGGCAAATTATCGTCAActtaccataaaaaaaacaaagaagccACCTGCGGCGGCCACCACACGTTGTCATTTAGTATTGGCAAAAGTTTCGGATAATGAAGAAACGTATACCATAACAAATagcgacgaggaggaggatctTATGCGTGCAAACGAAAGCAAGGAGATGGAGCCAGAGCACGAAGTCGCGGTGCCGGCCGATAAGTTGGACGACGTAGTTGAGCATTACATTTATGATGAGTTTCGCAAGTGCATCATCTTTCCCTCTGAAAGAAATGAGAAAGATCCAATGACTGAAATGCAGACGGAGACAGTCCTCACTTTTAACATTGACACGGATGATGCGGTTGAGGAAGACACTTGCATATTGAGGAATCCTCTAACGGAATTCGCTGATAGACAGGCTCGTATGAAGATGAGCGTTGAAATGGAACAAATACCCGAGCTGGCTCAGGTGCCAGAATCAACACTTAAGAATGTAATATTAGAGAACGATACCACAAAAGAGGAGGCACGCATATGCAAGAAAGTAAAAAAGATGCATGAAACTGGGACAACTGATCGGCAGCATTTCAATAAAGAGGACTCTCCAGATGTGATGGAACTTCTCATGAGCATATCAACGGATACCGAGAAGGGCGAAACTGATACCCAGTCGAAGTTAATACCATTTGAGTGCAGGTGGTGCAGCAAGGTAATTTCGCGcgaagaaaatataaaatggcaTGAATTGCGTCAATGTGGCAAGGTGTCGTATGTCTGCCAGGTGTGTGGCAACGCATTCATGACTAAGTTCCAGCTAAGTAGACACACGTCCTGTCACAATAACAAGCAGACGTCCAAAAGAAAACCTCTTGGAAATAAGAACACGCCGTCacccaaaaagaagaaaccaGAAGACAGTCACAAGAATGATCGTCAGGATCGTAAGGAGAGCATTTCTCCCAGAAAAAATCGTAGCACCGAAGAATTTCCATGTCCGGAGTGCAACAAGAGGTTTGACTCGAAGGAAAAGCTCGATTTTCACATGAATGAGATGTGCCATAAATGTCCCCAGTGCTCACGCTTCTATGCAAATAAACGCAGTCTAATGCGACATCTCAAGGATCACAATACATTGGAACTCTTTGATTGCCGCCGTTGCCCGCGCTCATTCACGGAAATCGATGACTTCCTGGTGCACAAGAACACCCACAAAAACGATGGACCATTTAACTGCATTCAATGCAATGCAGAATTCAACGACGTAATTTATCTGCAGATCCACGCTAAGCTGGAGCATAGCCAAGAAGTTACAGAACCTTCAAAACTGAAGCAAAGCCAAGGAGATACTGGAGCTACTCCCCGTAGTTCCACGAAACGGAACAAATCGGATCACCATCAAGAACAAGGGCAACTGGAGCGCAGCCAAAATGATACATTAGCCTCAAAACTGGAGCGCAGCCAAGGAGATACAGAAGAACTAAAACTGGAGCATAGCCAAGGAGATGCAGGAGCATTAAAACTGGTGGATAGCCAAGGATATACAGGAGCTACTCCCCGTAGGGCCAGGAAACAGATCAAATCGGATCGCCATCAAGAACAAGAGCAACTGGAGCGTAACCAAAAAGATACATCACCTTCAAAATTGGAACGTAGCCAAGGAGATACAGGAGCTACTCCCCGTAGTGCCAGTAAACAGATCAAATCGGATCGCCATCAAGAACAAGGGCAACTGGAGCGCAGCCAAGAAGTTACTAGAGGTAGTCCCTGTGGGGCCAGGAAACAGATAAAATCGAAGCAGATTGATTCAGAAATGCTTTCCCCAAGTCTCTCAAGGAGTCCATCATTGCCAAAGAAGATGAAGTGCGGCGACGACACCGACGATACCGACGACACTGATACATTAAGCCATACCAAGAGCCCATCACTGCCAAAaaaattgaattttgcgTGCAAGAAGTGCGATGAGAAATTTACGTCAGTAACTTCACTGTCTGCTCACACTCATACGCACTCGGACGTCGGATGTCCTCACCACGAGTGCACGTTTTGCAAGAAGACATTTAATCGCAAATATAAACTGGTTGAGCACATTCGTAATCACACTGGCGAACGTCCTTACGAGTGCTCGCACTGCGACAAGAAATTTCAGCTCAAGCGCTCCCTGGATAGTCACAGTCTTGTCCACACTATTGGGGATCGTCCTTTCGCTTGCTCGCATTGTAGCAAGACATTTTTGAGCAAGTATGACCTGAATGAGCATGCTTGTACGCACTCTGCCGCTCGTCTTTACGAGTGCACACAGTGCGACAAAAAATATACGTCGAAGCAAAACTTGGACAGGCACCTTCTTTTTCACGCTGGGAAACTTCCTTACAAGTGCTCGAACTGTGGCAAGAAATTTGTGAGCAAGCATGAATTGATTGGACACGCTCTTACGCACTCTGACTCTCGTCCTTACAAATGCTTGATTTGCGAGATGCCATTTAAGACTAAGTATTCGCTACAAAGGCATGGTCTTGTACACTCTGGCAAGCGTCCTCACGAGTGCTTGGATTGCGGCAAGAAATATTCTCGCAAGAACTCTCTAGATAGGCACAGGCTTCTTCACATTACTCTGGTTCGTCCTTTCGCGTGCTCGCATTGCGACATGAAATTTTTGCGCAAGGATGAATTGAATGGACACGTTCGTAAGCACTCTGACGAACGTCCTTACGAGTGCACGCAGTGCCACAAAAAATTTAAGGCCAATCAATCGTTGATTAGGCACACTCAAATTCACACTGGCGAACGTCCTTACGAGTGCTCGCAGTGCGACAAAAAATTTGCGAAAAAGTACGACCTAAAGGAGCACACTCTTATTCACATTGGCGAATGTAATTTCAAATGCTCAGATTGTGGCTTGAAGTTTCTGCGCAGGCGTGACCTGGTTGCGCACGCTGTTATTCACACTGGCGAACGTCCTTACAAGTGTTTAGCTTGCAACAAGAAATTTCGATCAAAGTATTTCCTGGAATCGCACACCAGCAAGTACACGGATAAAGGTCCCTACAACTGCAGGCTCTGCGGCATTAAATTTGAGCAAGGGTGTGTGCTAAATCAACATGTTACTCTTACCCACGAGTCTCACGAGTGCTTGCCCTGCGACAGAAAATTCAGTTCAATTGCAGATCTTGACGAACATATGCGAGGACGAAAGTTTCAAACTGGAGATGCACAAAATGGCGGCGTCTAA
Protein Sequence: MSQYICLSCIQAAQNAYRFKLILEQSMANYRQLTIKKTKKPPAAATTRCHLVLAKVSDNEETYTITNSDEEEDLMRANESKEMEPEHEVAVPADKLDDVVEHYIYDEFRKCIIFPSERNEKDPMTEMQTETVLTFNIDTDDAVEEDTCILRNPLTEFADRQARMKMSVEMEQIPELAQVPESTLKNVILENDTTKEEARICKKVKKMHETGTTDRQHFNKEDSPDVMELLMSISTDTEKGETDTQSKLIPFECRWCSKVISREENIKWHELRQCGKVSYVCQVCGNAFMTKFQLSRHTSCHNNKQTSKRKPLGNKNTPSPKKKKPEDSHKNDRQDRKESISPRKNRSTEEFPCPECNKRFDSKEKLDFHMNEMCHKCPQCSRFYANKRSLMRHLKDHNTLELFDCRRCPRSFTEIDDFLVHKNTHKNDGPFNCIQCNAEFNDVIYLQIHAKLEHSQEVTEPSKLKQSQGDTGATPRSSTKRNKSDHHQEQGQLERSQNDTLASKLERSQGDTEELKLEHSQGDAGALKLVDSQGYTGATPRRARKQIKSDRHQEQEQLERNQKDTSPSKLERSQGDTGATPRSASKQIKSDRHQEQGQLERSQEVTRGSPCGARKQIKSKQIDSEMLSPSLSRSPSLPKKMKCGDDTDDTDDTDTLSHTKSPSLPKKLNFACKKCDEKFTSVTSLSAHTHTHSDVGCPHHECTFCKKTFNRKYKLVEHIRNHTGERPYECSHCDKKFQLKRSLDSHSLVHTIGDRPFACSHCSKTFLSKYDLNEHACTHSAARLYECTQCDKKYTSKQNLDRHLLFHAGKLPYKCSNCGKKFVSKHELIGHALTHSDSRPYKCLICEMPFKTKYSLQRHGLVHSGKRPHECLDCGKKYSRKNSLDRHRLLHITLVRPFACSHCDMKFLRKDELNGHVRKHSDERPYECTQCHKKFKANQSLIRHTQIHTGERPYECSQCDKKFAKKYDLKEHTLIHIGECNFKCSDCGLKFLRRRDLVAHAVIHTGERPYKCLACNKKFRSKYFLESHTSKYTDKGPYNCRLCGIKFEQGCVLNQHVTLTHESHECLPCDRKFSSIADLDEHMRGRKFQTGDAQNGGV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00611481;
90% Identity: -
80% Identity: -