Basic Information

Insect: Drosophila novamexicana
Gene Symbol: -
Assembly: GCA_003285875.3
Location: NW:4137747-4142828[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 9.3 4.9e+02 1.0 1.9 3 16 57 70 56 72 0.84

2 14 1.3 71 3.7 1.4 1 23 171 197 171 197 0.88

3 14 0.00022 0.012 15.6 0.7 1 23 203 226 203 226 0.97

4 14 0.00036 0.019 14.9 4.6 1 23 231 254 231 254 0.96

5 14 0.00038 0.02 14.8 4.5 1 23 259 281 259 281 0.98

6 14 4.9 2.6e+02 1.9 5.7 2 23 288 311 287 311 0.90

7 14 0.00042 0.023 14.7 1.0 3 23 321 342 320 342 0.95

8 14 0.022 1.2 9.3 0.3 1 23 348 371 348 371 0.95

9 14 0.12 6.4 7.0 0.2 5 23 387 406 382 406 0.89

10 14 2.7e-05 0.0014 18.5 0.4 1 23 435 457 435 457 0.98

11 14 2.5e-06 0.00013 21.7 4.2 1 23 463 485 463 485 0.97

12 14 7.8e-06 0.00042 20.2 0.1 2 23 492 513 492 513 0.97

13 14 0.0011 0.057 13.5 0.9 1 23 520 542 520 542 0.99

14 14 0.00069 0.037 14.0 5.0 1 23 548 571 548 571 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	9.3	4.9e+02	1.0	1.9	3	16	57	70	56	72	0.84
2	14	1.3	71	3.7	1.4	1	23	171	197	171	197	0.88
3	14	0.00022	0.012	15.6	0.7	1	23	203	226	203	226	0.97
4	14	0.00036	0.019	14.9	4.6	1	23	231	254	231	254	0.96
5	14	0.00038	0.02	14.8	4.5	1	23	259	281	259	281	0.98
6	14	4.9	2.6e+02	1.9	5.7	2	23	288	311	287	311	0.90
7	14	0.00042	0.023	14.7	1.0	3	23	321	342	320	342	0.95
8	14	0.022	1.2	9.3	0.3	1	23	348	371	348	371	0.95
9	14	0.12	6.4	7.0	0.2	5	23	387	406	382	406	0.89
10	14	2.7e-05	0.0014	18.5	0.4	1	23	435	457	435	457	0.98
11	14	2.5e-06	0.00013	21.7	4.2	1	23	463	485	463	485	0.97
12	14	7.8e-06	0.00042	20.2	0.1	2	23	492	513	492	513	0.97
13	14	0.0011	0.057	13.5	0.9	1	23	520	542	520	542	0.99
14	14	0.00069	0.037	14.0	5.0	1	23	548	571	548	571	0.98

Sequence Information

Coding Sequence: ATGGAAACGTGTCGCACTTGTGCAAGGTGCGATTTCgaaaatggcaacaactaTTGGCTGGACATGTTCCATCCAACGCGTTGGCAGAGCGAGATGGCGCAAATACGCTTGGAGTTTGTCAACTGGAAGTTACAGATCTCACCAAACGATGGACTGCCCCAAAAAATTTGCAGCGATTGCTTTACAAAATTCTGCTCCATATACACTTTTCGTATGGCCTGCCAGGACGCACAGTTAAAGTTGTcgaatatttttgataaaatagATGCGAATTCGCTCTATGATAAAAACGACGAGGACAATATTGAGGTGGATGTGGATGAAATAAAAGCCGCGACCGAAATAGTAACagaaacaacgacaacaacacaaaacacTGCCAATATTGAGGCCAACACGCAAACACCCATAGAAATCTTTGTGGAAACGATTAGCATCAACGAATCTGAATCCTTACAGCCAGATGAGGAAACCGATTTAGCTTCAGATTACAACACATTAAACATAAGCTATGCTTGTAAATTTTGTCACAAGCCACAGGAAAGCTTTGAGCTGCAGCACCTATTACTAGAGCACATTAGTAACGCACATGATCCGGATCAGCCCTACAACTGTCCGGAGTGCACAGAGTGCTTCCAAGATGCCGCATCGCGTACGGTGCACATGAAGAGCATTCATGTGGTAAAGCATCACACCTGTGAGGTGTGCGGCAAAAAGTACGGAGATCGTCATAATCTCGACCatcatattgaaaaatatcacTCGGAAACGGATTTCGAGTGCAGCCTGTGCGAGAAACGTTTCTTTACGCGTAAAAGCTTGCACTACCACATGAACTGGCACAATCCGGAGCGCCAGCTCAGATGTCGCCACAGCGGCTGCGACAGGCTGTTTATCAACCAACGACATCTCAAGTGTCACGAGGCAACGCACTCAACGGGCCCCCGCAAGAGCGAATACTGCGGCTTCTGTGGTAAAGCTTTCATACACGTTAAAACTCTACGTTGGCACATCTATCGACAGCATGGCGGAGAGAAGCCTTTTAAGTGCGCCAACTGCACTGAGGttttTGGCTCCTATGCGGAAAAGCGCTTACACATGCTGGAGCAGCACACGGAAAATCTGACTCATCAGGAGCGCAGCGAATGCATGTTTCAGTCCTGTCGCCAGGAGTTCGACACCGAACAGGAGCTCATCCAGCACATGAGCGTTGAGCATGTGCAGCGCGAACCCTCCACCCCGATAATTGCGAATAATAAACGCGTGCTCCAGTGCAAACGGGAGCGACAGTATACGGGTCTCTTCCAGTGCGGCAGCTGTACGCAACGTTTTAACATGAAGTCCGCCCTGGAGCGGCACATGGCTGTCCATTCTGCTGACCGGCTGCATGCCTGCCCGCACTGCTCTAAGCGGTACAAGCGTGCCCAGGACCTGAAGTGGCACATGAAGACGCACGCCAATGAGAAGCCCAATGTGTGCGATGTCTGCGGCAAGGCGTTTGCCCTGAAATATGTGCTTACCCAGCATATGCGCAGTCATGAGGTTCTCGAGAAGAACTTCAAGTGCGAGACCTGCGGACGGGCCTATCTGTTTGAGAAGTCTCTGCGTCTGCATCAGCGCGTTCACACGGGCAACACCTACTACAAGTGCGATTTGTGCCAGGAGCGTTTTGTCACTCACATcaaatttaaaaCTCATATGAAAAAGACACATGATAGCAGCCAGTCGCATGCCAAAGATACGCTGGATGATTTGATCAACATTGTGATTTCCTGA
Protein Sequence: METCRTCARCDFENGNNYWLDMFHPTRWQSEMAQIRLEFVNWKLQISPNDGLPQKICSDCFTKFCSIYTFRMACQDAQLKLSNIFDKIDANSLYDKNDEDNIEVDVDEIKAATEIVTETTTTTQNTANIEANTQTPIEIFVETISINESESLQPDEETDLASDYNTLNISYACKFCHKPQESFELQHLLLEHISNAHDPDQPYNCPECTECFQDAASRTVHMKSIHVVKHHTCEVCGKKYGDRHNLDHHIEKYHSETDFECSLCEKRFFTRKSLHYHMNWHNPERQLRCRHSGCDRLFINQRHLKCHEATHSTGPRKSEYCGFCGKAFIHVKTLRWHIYRQHGGEKPFKCANCTEVFGSYAEKRLHMLEQHTENLTHQERSECMFQSCRQEFDTEQELIQHMSVEHVQREPSTPIIANNKRVLQCKRERQYTGLFQCGSCTQRFNMKSALERHMAVHSADRLHACPHCSKRYKRAQDLKWHMKTHANEKPNVCDVCGKAFALKYVLTQHMRSHEVLEKNFKCETCGRAYLFEKSLRLHQRVHTGNTYYKCDLCQERFVTHIKFKTHMKKTHDSSQSHAKDTLDDLINIVIS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00502704;
90% Identity: iTF_00531129;
80% Identity: -