Dniv003949.1
Basic Information
- Insect
- Drosophila niveifrons
- Gene Symbol
- -
- Assembly
- GCA_035046325.1
- Location
- JAWNOC010000046.1:2748082-2752724[+]
Transcription Factor Domain
- TF Family
- MBD
- Domain
- MBD domain
- PFAM
- PF01429
- TF Group
- Unclassified Structure
- Description
- The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 1 9.2e-14 2.2e-10 39.9 0.0 8 71 388 448 382 452 0.87
Sequence Information
- Coding Sequence
- ATGATGAGTGTCCCATGTGATACAATTGACACGGGCAGCGACAGTCAAATGTCGAGCAATGATTTGACTTCGTTTGAGGATAATCGTTTGAACTATACCAGTGATTCGGACTCCACGAAATCAGGTGCTTCATTGTCTCAAAATCGAGGAAGATCGAAAAGAAAGCGCACCAAAGCAAAAATGCGTAGCAATTCAAAGGATATGGCACTCGCTGGATTCACTGGCAGCTATCCAAAGATGTTGATCACAAACAGCACCGAAAGCAACTCGGATGCCGATGGGGATCCGCCGCTGCCCGCTGATCTAAAGGCCATCTGTGCCACAGGCCTGAGCGTATTCCCCAGAGAGGAACAGCAAACGCAGTCGCCATCAGAGTCCGATACGTCGTCGTCCAATTTTGTCAACAAAACGTTAGCGAACACTACgagcccagcagcagcaacgacgacgacgacgatgtcgacaaccacagcagcagcatcagccacaacagcagcaaccacaacaacaatctcaaatacaaatacgttAAATTCGACTATCGAAAGTCCAAAGCcaagcgacgacaacaacagcgtcgATAACAACGACGATCGCAACGACAACAGTAGTTTGCCTAACGTTGTCGATCGTCTAGCATCAGAAGAGCAACATCAAGAGCCACCAGCCACATCATTTGAACTTGAACCTCAACCAGAAACACCATCTCATCCTCCAGAGCCTGAACCAGAGCCACAATCTGAATCTTCAGAACCACAAACTGAATTGCCTAACAAGAAGCGCAAAAAATATGCCGACGATGCTGCTTGCGAAGATTCTTTGCTGCATCCCCAGTTGCCAACGCAGGAGGAAACATCAAAGGGCTCTTTGACAAATAACGATAGCAGCTCGCGTAAACGCAGCTTCAACGGACAAGTAAATGAGAATATGCGCATACGCTCCAAGTCAATGAACCACTCCAATAACGACATCGATATCGGGCAGCAAAATGCACGCGCTCGCAGCGTTGGCCCCATAAACGAGGAGATTGCTGTTCCCCTCAAGACTGCGGGTAACAGCCGCTCGACACCTACTGAGGATGCTGGAAACGATGCTGGAAATTCGACCGTGCGTCGTCGTTCGATTGCGGCCAATAAGCTGCCGTCTACTGATAGCTATTATAAGTTGCCCTTTAAATACGGTTGGAAACGTGAGCTGGTAATGCGCAGCGGCAATACGTCACAGTCGCGTCAGCGTGCCGATGTCGTCTTCATATCACCAGCTGGCAAAAAGATGCGATCTCGCGATGACATTATACCGCTGCTGAGCGGCGAACTGACCATCGATCATTTCTGCTTCCAGCGCGCGCTGCAGAACGCTGGCGAGGAGTTTGAGACAATGCGCACTGCCCAACCGGTGGTGGAGCATCGCAAATCGATGGCAGCCGCCAAGCAGCTACgcgaggagcagcagcagcaactcaaaTCGCAGCCGAAGCAAACGCAGTCCCATCCAAAGACACCAGCAGTAGTCAAGGAAGTGCCACAAACGCCTCCGGTCGAGTTAGTTTCTGGCAAACGTGTGCCCAAGCCAAAGGCACCCAAGGGCGCCAGTCCCCCGCCACAGGGTTGGACTCCGACTATGGCCGTCAAGGGCAATGCGCGCGTCTTGGCTGCCAGCAACAGTAACGATGGCGGTGGCACCGGATCTCTAGGCAGTCACAATGCACGCAAGCGCAGCAATCagcacacaaagcaaaagcagccacAGGCTGCTGGATCAAAGACACCAATGATTCATCAGCAGGGCGGAGTATTGCCGCCTAAGCAACTGGTGGATAACACCATTGTCTGTGCTCTTTGTATGTTGAGCATCAAGGATAAGAAGCAGGCCTTTGCAATGGGCGCACCGAATGGCAAGACCGACAAATACATTTGCACGAGCTGTATTAGGCCCGAATCGTCACTGGCGCACCCCAACAAAAAGGAGAAGGAtaaggagaaagagaaggaaaaggaACCTATCGATGAGAATGTTAATGCCAACAACTTGAGCATCAATGATTTAAGCTATCAAAAATCATTCAGCTACCAAGAAGCGCTAATGGAGTTGAGcggcaatagcagcagcagcttggctGAAATTGCGGAGATTAAAACGCCTTGCCCATTGCCGCCAGAGCAGCTGTTCAACGAGTCGCCCATTAAAGTCACACCGAAGCCACAGGAAATTGTTGTCATCAATGGTCGCAAGGCTGTCGCTGTGTATGGACCGCCTCAGCGTGCCCAGTTGCAAGTCATTGCACGTGAATCAAACTTGGTCAATATGGAAAAGTTTTATGGCACGCACTTTTCCAATGGaaagaataatattgaaaGCATTGTCCAATCCGTATCGTTGGGGAATATTAACTGCCAAGTGCTGTTGGCTGTGATGAAAACACTGGACTTCCATGATCGCGTGCGCATGTCGAAAGTGTGCAATACTTGGGCCATGATTGGTCGCGATCGCAACGTCTGGCGCACAGTCAAGTTACGCGACACTCACGTGACCAACTGGACGCTCTGCTTGCGTGACATGGTGCGCTATCGCACCCGTGAGCTGGATATGATGGGCGTCAAGATGGACAACCCCAAATTGCGTATGGAGGGCGATTTGCGTAGCTTGAAATCATTGCGTGTGCTTCGAACGGATGCCACAGACGCCGAGTTTATTCAGCTGATACTAAGGCGTTTGCCGCGCCTCGTCGAGCTGCGTGCTACTTGCACCAGCCGAAACCTGAGCTTGTCCCAGCTTGACAAGATGTCGGAGCTGCGAGTGCTGCGCATTCGCATGACCGAGCCCAAGGCCAGCATCGTTTCCCTAACGCCCATGCAGTCCTTGACCAAATTGCGTGAGCTAAGCTTGCGCGGTGTGAACAACATGAGCCAACTGGACTTGCTCCATCTAAAGGGATTGCAGCAATTGGAGACCCTTTTACTGGGCTCCTGTCGTGGCATGAAAACTCGCACCTTTGGTGAAGAGGTGCTGCCTAACCTGAAGCGTCTGCGGCATTTGCGAGTCGAGAATAACGGAAATCGTTCGTTTATCATCAACGAGATTATGAGTGGCCTGGCCGCTGGTGGCACTGTCCAGCGTTTGGAGTTGATCAACGTTAATGTGGATAAAGACTTCAGTCGCCAGCTCACAGATTGCAAATCCGTTAAGGAGCTGCTTCTGATGCCCAATTTCATTCAGAATACCGCCTACATGGTTCACTATATCATGCAGGCCATTAATGAAAACAGCGAACAGCTGATGGTTTTCCGATTGGGTCTCAGCTTTGAGCTGCTCAGTGCGACTCGCGCCTTGGCCATGAATCCGGAGAAAGACTGCATCCCAGTGGTGCTACCGATACCAGGCGTGCCACCGAACGACAAGTTGAACAACTCGGCGGAGCCGATCGCCTATTTGCCGGTCGATCGCCTCGAATCGATACTGCATCACATGATGCCGCAGGCCTGGCTGACAGTTGCAAAGGTGCCGCAAAGCGAAATAACAAACCTTAAGTTCCTGTCGGCTCCAGTTAACGTAATCTAG
- Protein Sequence
- MMSVPCDTIDTGSDSQMSSNDLTSFEDNRLNYTSDSDSTKSGASLSQNRGRSKRKRTKAKMRSNSKDMALAGFTGSYPKMLITNSTESNSDADGDPPLPADLKAICATGLSVFPREEQQTQSPSESDTSSSNFVNKTLANTTSPAAATTTTTMSTTTAAASATTAATTTTISNTNTLNSTIESPKPSDDNNSVDNNDDRNDNSSLPNVVDRLASEEQHQEPPATSFELEPQPETPSHPPEPEPEPQSESSEPQTELPNKKRKKYADDAACEDSLLHPQLPTQEETSKGSLTNNDSSSRKRSFNGQVNENMRIRSKSMNHSNNDIDIGQQNARARSVGPINEEIAVPLKTAGNSRSTPTEDAGNDAGNSTVRRRSIAANKLPSTDSYYKLPFKYGWKRELVMRSGNTSQSRQRADVVFISPAGKKMRSRDDIIPLLSGELTIDHFCFQRALQNAGEEFETMRTAQPVVEHRKSMAAAKQLREEQQQQLKSQPKQTQSHPKTPAVVKEVPQTPPVELVSGKRVPKPKAPKGASPPPQGWTPTMAVKGNARVLAASNSNDGGGTGSLGSHNARKRSNQHTKQKQPQAAGSKTPMIHQQGGVLPPKQLVDNTIVCALCMLSIKDKKQAFAMGAPNGKTDKYICTSCIRPESSLAHPNKKEKDKEKEKEKEPIDENVNANNLSINDLSYQKSFSYQEALMELSGNSSSSLAEIAEIKTPCPLPPEQLFNESPIKVTPKPQEIVVINGRKAVAVYGPPQRAQLQVIARESNLVNMEKFYGTHFSNGKNNIESIVQSVSLGNINCQVLLAVMKTLDFHDRVRMSKVCNTWAMIGRDRNVWRTVKLRDTHVTNWTLCLRDMVRYRTRELDMMGVKMDNPKLRMEGDLRSLKSLRVLRTDATDAEFIQLILRRLPRLVELRATCTSRNLSLSQLDKMSELRVLRIRMTEPKASIVSLTPMQSLTKLRELSLRGVNNMSQLDLLHLKGLQQLETLLLGSCRGMKTRTFGEEVLPNLKRLRHLRVENNGNRSFIINEIMSGLAAGGTVQRLELINVNVDKDFSRQLTDCKSVKELLLMPNFIQNTAYMVHYIMQAINENSEQLMVFRLGLSFELLSATRALAMNPEKDCIPVVLPIPGVPPNDKLNNSAEPIAYLPVDRLESILHHMMPQAWLTVAKVPQSEITNLKFLSAPVNVI
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00556520; iTF_00553726; iTF_00472358;
- 90% Identity
- -
- 80% Identity
- -