Basic Information

Insect: Drosophila nigromelanica
Gene Symbol: -
Assembly: GCA_004149445.1
Location: SCDR01000394.1:8255-11075[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 6.5 7.8e+02 1.4 2.1 1 23 334 357 334 357 0.91

2 8 0.00071 0.086 13.9 0.8 1 23 365 387 365 387 0.97

3 8 4.4e-06 0.00053 20.8 0.6 3 23 396 417 395 417 0.96

4 8 0.00032 0.038 15.0 0.1 3 23 426 447 424 447 0.93

5 8 0.071 8.5 7.6 0.5 2 23 456 477 455 477 0.96

6 8 0.57 68 4.8 0.8 1 23 486 508 486 509 0.91

7 8 1.7e-05 0.002 19.0 0.3 1 23 514 536 514 536 0.97

8 8 0.017 2 9.6 8.2 1 23 542 565 542 565 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	6.5	7.8e+02	1.4	2.1	1	23	334	357	334	357	0.91
2	8	0.00071	0.086	13.9	0.8	1	23	365	387	365	387	0.97
3	8	4.4e-06	0.00053	20.8	0.6	3	23	396	417	395	417	0.96
4	8	0.00032	0.038	15.0	0.1	3	23	426	447	424	447	0.93
5	8	0.071	8.5	7.6	0.5	2	23	456	477	455	477	0.96
6	8	0.57	68	4.8	0.8	1	23	486	508	486	509	0.91
7	8	1.7e-05	0.002	19.0	0.3	1	23	514	536	514	536	0.97
8	8	0.017	2	9.6	8.2	1	23	542	565	542	565	0.97

Sequence Information

Coding Sequence: ATGATCTGCCGCTTGTGCCTGTCCGATCTCGACAATTCGGTGTCCATTTGCATATTCAGCGATGCCAGCGCCCAAAACCTGGCCCAGGCCattgccaaatatttgcagctcgagTTGACGACCGGCGACAGCATCTCGACGCGGCTGTGCACAGCGTGTTGGCGCCAGTTAAACGATTTTGAGCAGTTCTGCGCAATGGTCGCCGAcaagcagcaggcgctgcagctgaAAACGGAACCGGAGCCGCCGCCCGAGCCAGCTGTGGTCGTTTGGAACACGGAATCGCCCATCGAAACGAAGCTGGCCTTCGACGAAGATGTCAAGGATCACATACTCTGCGAGCCCGAGATCGATGTGCACGACGGCACGCAATCCTACGGCAatgacagcagcgacaacaacagcagcagcagcgacaacagctgcagccgcgggaggagaagcagcagcgacgacagCGAGCACGCAGCTGAGGGTGAGTTTGCGCTGGCGTTGCCCAAGTCCAGGGCCAGGCAAACCCGTGGCCGAGCACAACAGACGCCCGCCAAGGCAGCCAAAGCGGTTGCCACCgcctgctcctcctccagcAGCACCCAGCGCGAGTCGCGCTTGCGTACGCGTGAGCTGAGACGCATCGCCGCCACAGCTGGCACGCCAGAGCCGCCAGCCAAGACCAGCAAAATCAGTAAACCACGCGGTCGACCCAGAGGCAGCAATGCGAAGCCAAAGCCCCGGCTGGCCAAGCCCAAATCAGAGAAGCCGGACGATACCGAGCTGGAGGCGAAGCGCAGCAGTATCAAGCAAATGGACGACTACATTGCCGCCAATGTGAAGCTGGACTGTTGCCTCTGCGCGGCGCCGCTGCAGAACTTCATCGAGCTGAAGCGACACTTTCGCGCCGAGCACAACTGCACCGGGTACATGGAGTGCTGCAACAATCGGTACAAGAAGCGCACCCTGTACGTGGACCATCTGCACTATCACAAGGATCCGCAGTACTTTAGCTGCAAGCCGTGCCGGAAGAGCTTCCTCAATCGGAACAGCCAGGACATGCACATGCTGCGCTTCCATtccgatcagcagcagctggtgcatCAGTGCGCCATTTGCGAGGCGCGATTCGCCAAAAAGTTTCTGCTCACCATGCACATCAAGGGCCACAAGGGCACCGAACGCCCCGAAATCTGCGAGACGTGCGGCAAAAGCTTCCGCACCAAACTGGAGCTGACGGCGCACGTGAAGCGCATGCATACGGCGGATTTTACGCCCGTCATCTGTGACATTTGCGGCGTCAACTTTCGCTCCAAGGCGAACTTTCTGATACACAAGAAGGCGCTGCATCCGGAGGGTCCCGTCGCCGAGGTGCAGTGCAATCTGTGCAGTCGCTGGCTGCGCGACGAGCGCAGTTTGCGCAAGCATTTGGCCCGGCACGACGATCGCGATGGCGACAGCAAATACCGCTGCGTCCTCTGTAGCGCCGAGAAGGCGTCCCGGGTCGCCCTCAGCAGCCACATGCGCTACCATCACTCGAACAAGCGGCACAGCTGCACATTGTGCGGCAAGGAGTTTAAGTTGCCGCGGGCGCTAGCTGAGCACATGGCCACCCACACGGGCATCGATCTGTATTCGTGCCAGTTCTGCACGCGCACCTTCAAGTCCCACGCGAATATGCACAATCACAAGAAGAAGATGCATCCCAATGAGTGGGTGCGCAAATATACACAGCCCagtgctggcggcggcggcccaCCAAATGGCACAGCCACCGAGGAGCCGACGGACAAGGAGCTGGTCGAGATCGAGGTCGAGGAAACGCAAGAGACGACGGCAGACGCGGATGGTGGCTTCGAGTACTTGGCCAATGGCAGCGATGTTTGTCCGCTTTGA
Protein Sequence: MICRLCLSDLDNSVSICIFSDASAQNLAQAIAKYLQLELTTGDSISTRLCTACWRQLNDFEQFCAMVADKQQALQLKTEPEPPPEPAVVVWNTESPIETKLAFDEDVKDHILCEPEIDVHDGTQSYGNDSSDNNSSSSDNSCSRGRRSSSDDSEHAAEGEFALALPKSRARQTRGRAQQTPAKAAKAVATACSSSSSTQRESRLRTRELRRIAATAGTPEPPAKTSKISKPRGRPRGSNAKPKPRLAKPKSEKPDDTELEAKRSSIKQMDDYIAANVKLDCCLCAAPLQNFIELKRHFRAEHNCTGYMECCNNRYKKRTLYVDHLHYHKDPQYFSCKPCRKSFLNRNSQDMHMLRFHSDQQQLVHQCAICEARFAKKFLLTMHIKGHKGTERPEICETCGKSFRTKLELTAHVKRMHTADFTPVICDICGVNFRSKANFLIHKKALHPEGPVAEVQCNLCSRWLRDERSLRKHLARHDDRDGDSKYRCVLCSAEKASRVALSSHMRYHHSNKRHSCTLCGKEFKLPRALAEHMATHTGIDLYSCQFCTRTFKSHANMHNHKKKMHPNEWVRKYTQPSAGGGGPPNGTATEEPTDKELVEIEVEETQETTADADGGFEYLANGSDVCPL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00496176;
90% Identity: iTF_00542024;
80% Identity: -