Dmea006981.1
Basic Information
- Insect
- Drosophila melanica
- Gene Symbol
- -
- Assembly
- GCA_004143765.1
- Location
- SCDT01001614.1:24826-28318[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 9 5.4 5.4e+02 1.6 0.5 3 23 275 296 273 296 0.79 2 9 5.9 5.9e+02 1.4 2.1 1 23 328 351 328 351 0.91 3 9 0.0021 0.21 12.3 0.8 1 23 359 381 359 381 0.97 4 9 4e-06 0.0004 20.8 0.6 3 23 390 411 389 411 0.96 5 9 0.00029 0.029 15.0 0.1 3 23 420 441 418 441 0.93 6 9 0.064 6.4 7.6 0.5 2 23 450 471 449 471 0.96 7 9 0.51 51 4.8 0.8 1 23 480 502 480 503 0.91 8 9 1.5e-05 0.0015 19.0 0.3 1 23 508 530 508 530 0.97 9 9 0.015 1.5 9.6 8.2 1 23 536 559 536 559 0.97
Sequence Information
- Coding Sequence
- ATGATCTGCCGCTTGTGCCTGTCCGATCTAGACAATTCGGAgtccatttgcatatttagcGATGCCAGCGCCCAAAACCTGGCCCAGGCGATTGCCAAACATTTACAGATCGAGTTGACGTCCGGCGACAGCATCTCGACGCGGCTGTGCACAGCGTGTTGGCGCCAGTTGAACGATTTCGAGCAGTTCTGCGCAATGGTCGCCGACaagcagcaggcgctgcaaCTAAAAACGGAACCGGAGCCGCCGCCCGAGCCAGCTGTGGTCGTTTGGAACACGGAGTCGCCCATCGAAACCAAACTGGCCTTCGACGAAGATGTCAAGGATCACATACTCTGCGAGCCAGAAATCGATGTGCACGACGACAAtgacaacagcgacagcgacaacaacagcagcagcagcagcgacaacagctgcagcagcgatgGCAGCGAGAATGCAGCTGATGCTGAGTTTGCGCTCGCTTTGCCCAAGCGCAGGGCCAGGCAAATCCGTGGCCAAACACAACAGACGCCCGCCAAGGCAGCCAAAGCGATTGCCAACGCCTGCTCCTCCTCCGCCTCCAGCAGCACCCAGCGCGAGACGCGTTTGCGTACGCGTGAGCTGAGACGCATTGCCGCCACAGCTGGAACGCCAGAGCCGACAGCCAAGACCGGCAAAGTCAGCAAACCACGCGGTCGACCCAGAGGCAGCAATGCGAAGCCCAAGGCCCGGTTGGCCAAGCCCAAATCGGAGAAGCCGGACGACAGCGAGCTGGAGGCGaagcgcagcagcatcaaGCAAATGGACGACTACATTGCCGCCAATGTGAAGCTGGACTGTTGCCTCTGTGCGGCGCCGCTGCAGAACTTCATCGATTTGAAGCGACACTTTCGGGTCGAGCACAACTGCACCGGGTACATGGAGTGCTGCAACAACCGGTACAAGAAGCGCACCCTGTACGTGGACCATCTGCACTATCACAAGGATCCGCAGTACTTTAGCTGCAAGCCGTGTCGGAAGAGCTTCCTCAATCGCAACAGCCAGGACATGCACATGCTGCGCTTCCATTCcgatcaacagcagctggtgcATCAGTGCGCCATTTGCGAGGCGCGATTCGCCAAAAAGTTTCTGCTCACCATGCACGTTAAGGGACACAAGGGCACCGAACGCCCCGAAATCTGCGAGACGTGCGGCAAGAGTTTCCGCACCAAACTGGAGCTGACGGCGCACGTGAAACGCATGCATACGGCGGACTTTACGCCCGTCATCTGTGACATTTGCGGCGTCAATTTCCGCTCCAAGGCGAACTTTCTGATACACAAGAAAGCGCTGCATCCGGAGGGACCCGTCGCCGAGGTGCAGTGCAATCTGTGCAGTCGCTGGCTGCGCGACGAGCGCAGTTTGCGCAAACATCTGGCCCGGCACGACGATCGCGATGGCGACAACAAATACCGCTGTGTTCTCTGTAGCGCCGAGAAGGCGTCCCGTGTCGCCCTCAGCAGCCACATGCGGTACCATCACTCGGACAAGCGGCACAGCTGCACACTGTGCGGCAAGGAGTTTAAGTTGCCGCGGGCGCTAGCTGAGCACATGGCCACTCATACTGGCATCGATCTATATTCGTGCCAGTTCTGCACTCGCACCTTCAAGTCCCACGCGAATATGCACAATCACAAGAAGAAGATGCATCCCAATGAGTGGGTGCGCAAATATACGCAGCCCAgtagcggcggcagcggcccACCAAATGGCACAGCCACCGAGAATCCACCGGATAAGGAGCTGGTCGAGATCGAGGTCGAGGAAACACAAGAGCCGACAACAGACGCGGATGGTGCCTACGAGTACATGGCCAATGGCAGCGATGTTTGTCCGCTTTGA
- Protein Sequence
- MICRLCLSDLDNSESICIFSDASAQNLAQAIAKHLQIELTSGDSISTRLCTACWRQLNDFEQFCAMVADKQQALQLKTEPEPPPEPAVVVWNTESPIETKLAFDEDVKDHILCEPEIDVHDDNDNSDSDNNSSSSSDNSCSSDGSENAADAEFALALPKRRARQIRGQTQQTPAKAAKAIANACSSSASSSTQRETRLRTRELRRIAATAGTPEPTAKTGKVSKPRGRPRGSNAKPKARLAKPKSEKPDDSELEAKRSSIKQMDDYIAANVKLDCCLCAAPLQNFIDLKRHFRVEHNCTGYMECCNNRYKKRTLYVDHLHYHKDPQYFSCKPCRKSFLNRNSQDMHMLRFHSDQQQLVHQCAICEARFAKKFLLTMHVKGHKGTERPEICETCGKSFRTKLELTAHVKRMHTADFTPVICDICGVNFRSKANFLIHKKALHPEGPVAEVQCNLCSRWLRDERSLRKHLARHDDRDGDNKYRCVLCSAEKASRVALSSHMRYHHSDKRHSCTLCGKEFKLPRALAEHMATHTGIDLYSCQFCTRTFKSHANMHNHKKKMHPNEWVRKYTQPSSGGSGPPNGTATENPPDKELVEIEVEETQEPTTDADGAYEYMANGSDVCPL
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00496176;
- 90% Identity
- iTF_00561319; iTF_00567835;
- 80% Identity
- -