Dnig006974.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila nigritarsus
Gene Symbol
RREB1
Assembly
GCA_035044305.1
Location
JAWNMF010000255.1:3608074-3614564[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 13 0.037 2.7 8.8 0.8 1 21 258 278 258 280 0.93
2 13 0.00034 0.026 15.2 0.2 1 23 290 312 290 312 0.98
3 13 0.00026 0.019 15.6 7.2 1 23 318 340 318 340 0.98
4 13 0.9 67 4.4 1.5 2 20 569 587 569 589 0.93
5 13 0.017 1.3 9.8 0.2 1 23 733 755 733 755 0.97
6 13 1.3e-05 0.00094 19.7 0.7 1 23 765 787 765 787 0.99
7 13 0.00085 0.063 13.9 2.0 1 23 793 816 793 816 0.97
8 13 0.003 0.23 12.2 2.0 1 23 1075 1098 1075 1098 0.95
9 13 8.8e-05 0.0066 17.0 0.3 2 23 1477 1498 1476 1498 0.97
10 13 0.15 11 6.9 6.3 1 23 1504 1527 1504 1527 0.97
11 13 9.6 7.2e+02 1.2 3.4 1 23 1647 1670 1647 1670 0.78
12 13 0.0086 0.64 10.7 0.5 3 23 1727 1747 1725 1747 0.96
13 13 0.0014 0.1 13.3 4.8 1 23 1753 1775 1753 1775 0.99

Sequence Information

Coding Sequence
ATGCTCgccacacagcagcagcaacagcagcaaccacaacagcaacaatcgcacacagcagcagcaactgcagcagcagcaacacaagaCGATGCTCGGGATTTGGGATTAATGGACACGCGACAACGTCGCGATTCGAGTACCTCAGAATCCTCGCTGGAGCATTTGGATTTGAGTCGCACGCCCAAAAAgttgagcaacagcagcggcgcaCCGCAGCCGACGTCGACGCCGCACGACACAGCAGTGACAGCGACGTCGCGCAAGCGAAAACTGCGACAGccacaccagcagcagcagcagcagcaacagttgccgctCTCCGAtgaggagcaacagcagcagcagctgttggaTTCGTCAACGCAGCGACCGCGTCACAAGCAGCGGCGCagcgctgttgctgccgctacCAGCGCCAGCATCGTTGTTGACTACAGCGCCAGCGGCGACGCCAGCTCGCTGCGCAAAAAGTTTCGACTGAATCGCAGTAGCGCCAGCAGCAATGCCGCCAACGGTGATTTATCCGAGTCTGGCTTTGTTGATGGCAGCGCCGTCAGTGGCTATCTgcttagcaacaacaacaataacaacaacaataacaatatcaacaacaatatcagtagtagtagcagcagcagcgcagtcgctcagtcagcagcagcgtcggCAGCGCAGCATGCGTCAAGCGTTAGCAGCTCGGGCGGCTCCTCGCCACAGGGCCTCTCGAGCGCCGAGTCGGGCATCGGTGCTGGTGATGAGCACATGAAATATCTGTGCCCCATCTGCGAGGTCGTCTCGGCCACGCCCCACGAATTCACCAATCACATTCGCTGCCACAACTACGCCAACGGCGACACCGAGAACTTCACCTGCCGCATCTGCTCCAAGGTGCTCTCGTCGGCATCCTCGCTGGACCGCCATGTCCTGGTGCACACTGGAGAGCGTCCGTTCAACTGTCGCTATTGCCACTTGAACTTCACAACCAATGGGAACATGCACCGACACATGCGCACCCACAAGCAACATCAGGcctcgcagcagcagcagcagcagccctcgcaacagcagcaaacaacccaacagcagcaacagccacaatcgcagtcgcagcaacagcgacgccAGCAACATGCGGGCGGAGCAGGCGCAACTGGCTCGGGATCGGGATCAGCACAGTTGTTGACGACGCGAGCGGAGAGCTATGAGAGTGATGCCAGCTGCTCGACGGATGTGTCCAGTGAGCTGAACagtcacagcagcaacagcaatcaatccaaccacaacaacaacaacaatagccacaaaacgaacaacaataacaacaacaacaacaataataataataataataacaatgaagATGAGCTCGAGCTGGAGGATGAGCAGCTAGTATTGAGCAACAAACAGCGACGCCTCAAGGCAGccctaaacaacaacaatataattaGGGATGAGGAGCAGGAGAATCGTGTGGATGATAATTCGGATGTGGACAGCGTTGAGAGTGTAGCCCAGGTGATAACAAGCACACCGGATGTGGCCACGTTGCTCGCCTCGGGCGGCACCTCGCCCACCCACTCGCATTCGGAATTACATTCACCGCCCCTGCTGCAGAGCTGCCCCGCCTGCAATTCGGGTGAATTTGAATCTGTGCCAGCATTGTGCGCCCATCTGGATGCCGAGCATGGGGACATACCGGCCAAGTGTCGCGAGTGTGAGGTAATCTATGCCACACATCGACAGCTGCAGGCGCACAGCTGTCGCGGATTGCCGCCGCTGCTTGGTGCGAGCTCATCGCCACTGCACAAGCAGGAGGAGAGCGAactggaggagcagcagcagcagcacgaggAGGACCACGaacagcagcacaagcagGAGGAACAGGAGCACGCCGAGCAGCGCGAATGTGAAGATTTCTTCCAGCAGCTGTATCTGAAGAATAAATCGTCAGCAACGCTTCTTCCCTCCCCGATCAAACATGAGCCGGCGGATCAGCGGCAGGATCTGGCCGATATTCAAAGCATACTCAATATGACCAGTTCCAGCTGCACATCCAGTTTCCTGCGCAATTTCGAGCAGTCGGTGAACACGCCCTGCTCCAGCCAATACAGCGTCGATGGACGCGATGGCGAGGAGGAGGCCCAGGATGCCTTCACCAATGAATTCCGCCGAATGAAACTGCGCGGTGAGTTCCCCTGTAAGCTGTGCAGCGCCGTCTTTCCCAATTTGCGGGCACTCAAGGGCCACAATCGCTACCATCTGTCGGAGGTGGGCGCCGCGGGTCCATTCCGTTGCAACATGTGTCCCTATGCCGTCTGCGACAAGGCGGCGCTCGTCCGGCACATGCGCACCCACAACGGTGACCGGCCATACGAATGCGCCGTCTGCAACTATGCCTTCACCACCAAGGCGAACTGTGAGCGGCATTTGCGCAATCGTCATGGAAAGACCAGTCGCGAGGATGTGAAACGTGCGATTGTCTATCATCCGGCCGAGGATGCCAGCTGCGAGGAGAACAAATCCCGGGCCGATGCAGATATGCTAACCGAGCTGAGCGGCTATCGCTGTCCCACACCCACGGAGCACAGCTCCTCAGCTAGCTCCTCGTCACAGCTAAAGCATATGTTGCTGGCGGAGACGACGCCGGCCGTAAaggtaacagcaacagcagcagcagcagtggcagcaacaacatcgcTGCCGCAACAACCGCTCAAGATTCAGGTGAAGAGCTTGGATCAGCTGGTGGATAAGCCACTGCCTGCACTCGATCTCAGCATGGATGCGCTTGACCTGAGCAAGAAGCCCGCACAGCTGCTGGCCGAGCAAAGGGAGCAGCTCGAAAGACAcgaattgctgctgcagcagcaacaccaacagcagcagcagcagcagcaacaacagcagcagcaacaaatgtttgGGGCTGGCGATGCAGCTGCTCAGTATATGCAACAGCTGTTGCACAGCTTTATGCTCCAGCAGGCACCCGGTTTTCCTTTCTTTGGCTTTCTCACACCGCCGCCACCAGCAacgacggcagcagcagcagacaagtcaatgccaacaaatccagcaggagcagccggagcaacagcagcaacaattgctgcaatGCCACTATCGCTGCCCGCTGGTGGTCCCGTCAAGATGGTCATCAAGAATGGCGTCCTGATGCccaagcagaagcagcgcCGCTATCGCACCGAGCGTCCCTTTGCCTGCGAGCACTGCTCGGCCCGCTTCACGCTGCGCTCCAACATGGAGCGGCAtgtgaagcagcagcatccacagTTCTATGCGCTGCGCCAGCGACACCGCAGCGGTCATCATGTGATGCGTGAACGGGCTGCGTCCTCGAATGCTGTCCAAGCGGCAGCCGCTGctcaggcagcagcagcaactgccgcAGCAATCAGTAATctcagccagcagcaacagttgcagcattcacattcgcatcACGTCCATGCGCCAATTTCGGAGCAGGTGAAATATGCGATTTTGGCGCAGCAATTGAAGGCGCGCAAGGATACGGATTTGTTGCAACAGGCACTGGCACATGGTTCCAGCAGTGTTGTCGCCAATCCGCTGCTGCATTttagctacaacaacaacggcaacagcaacaagcagcagcagcaacaacaattgggcAACAACACTGGCAACTCTTTGGTGATGGACGATGATGAGCCACCCAAGTTGATTATTGACGAGGATGACGAGGATGTGGAGGGAGAggacgatgaggatgaggaggaggaacaGGAATTTGATGTCGATGAGGATGAGCAGGAGGATGAAGAGATGGACTTGGACGaagagcatcagcagcagccgcacgatgaggatgacgatgacgacgatgatgatgttgatgatgatgctgcagcagcagcagcaacggagGCGtcgcagcaacaattgcagccaACAAAGGACAAACTGCAATCCAAGCCAATTGAGGCGGCCAAAAAGGTAGCGGACACCATATTGGAGCAGGCAATCAAAGAGCGCGAGGAGAAAGCCTCCGAGAAGCAGCCGCATACTCAAGCGAAGTCCCTGGGCAATAAGCCGGCGGCGCctacaacaatgaaaacaatgatTGCACAAGCGGAATCGGTGGCCAAGTCCTTGAAGGAGGTGGCCAGTTCACCGTTTAAGGATGAATCTCAGGATCTGGTGCCGGTGGCCAAACTGGTGGACAATGCCACCAGCAATCAGGTGTCCTTCAACAGCTATTTCCGTCCCAGCGACGTCGCCAATCACATGGAGCAGAGCGACGAGGAGGGTCTCGTCGCCAGCGGCAGCGCCAGCGAGAGCAACAATTCCGGCACCGAGGATgtgaccagcagcagcagcagctgcggcaacGATACCAAAAAGAAATCCGCCTACAGCCTGGCACCGAATCGTGTCAGCTGCCCATATTGCCAGCGCATGTTCCCCTGGAGCAGCTCGCTGCGTCGCCACATCCTGACGCACACCGGCCAGAAGCCGTTCAAGTGCTCCCACTGCCCGCTGCTCTTCACCACAAAGAGCAACTGCGATCGCCATCTGCTGCGCAAGCATGGCAACGTTGAGTCCGCCATGTCCGTCTATGTGCCCACCGAGGATGTCAGCGAACCGATTCCCGTGCCCAAGTCCGTCGAGGAGATTGAGCTCGAGGAGCAGCGACGTCGCCAGGCGGCCGAAGCCGCACAGGCCGAACGGGAGCAGCGCGAGCGTCAAAAGGAGCGCGAACgtgaactggaactggaacggGAGCGGGAACAGCAACATTTGATCCAACAGTATCGCCAACAAAtggccgctgctgcagcggctgctgttgctgttgccgctgtcgctgtcgctgcacCAGCGCATCCAACACCACCACAGCCAGCCCAATCGCCACCGGGCCTGGAGGCGAGCAGTGATCTGCCCTACAAATGCCATCTGTGCGAATTCTCGTTTGGCGAGCGGCTGCAGTGCCTCGAGCACATCAAGCAGCTGCACGCTCACGACTTCGCCCTGCTCCTGGCCAAAGGGGCCATCGAAACGGATgcacaactgcagcagcaacagttgccaatGGCCGGTGGTGCTCCACATTCGGATGAtgaggctgctgctgtcggCACCAGATCGGGCAAATATCCCGACTATAGTAATCGTAAAGTGATTTGCGCATTTTGCGTGCGTCGCTTCTGGTCAACGGAGGATCTGCGCCGACATATGCGCACCCATTCCGGTGAGCGTCCGTTCCAGTGCGAGATCTGCTTGAGGAAGTTCACATTGAAGCACAGCATGCTGCGACACATGAAGAAGCACAGTGGACGCAGTCACAATGGTGGCGAACTCGATCATCAATCCGATTGCTCCGATGATGAGCAACTGTTGCCCTGCTCCCCACCCTCAACGCCAACGcccactaacaacaacaacaacaacaacacttgccagaacaacaacaacaacaataacaacaacaatagcaataacaatagtAACAGCAAGCAGGTGCTGCGCGAGCTGCTCGGCAAGCCGAACGAGTGGCGAGTGAGCCGCCTGGGTGAGCACAAGGAGAACATTGccgaggcaacaacaacaccctcagcagcaacagcagcagcggcagcaacagctgcagcagcagcagcggcggcagcagcagcagctgtggccAGTGGCGATCTAATTGGTAATCTGTTAGGGATCAGTGATCAGGGCATACTAAACAAGCTGCTCTCCTCACCGGACGAAGCTGCCAAGCTGCTAGGCGTGGAGAAGTAA
Protein Sequence
MLATQQQQQQQPQQQQSHTAAATAAAATQDDARDLGLMDTRQRRDSSTSESSLEHLDLSRTPKKLSNSSGAPQPTSTPHDTAVTATSRKRKLRQPHQQQQQQQQLPLSDEEQQQQQLLDSSTQRPRHKQRRSAVAAATSASIVVDYSASGDASSLRKKFRLNRSSASSNAANGDLSESGFVDGSAVSGYLLSNNNNNNNNNNINNNISSSSSSSAVAQSAAASAAQHASSVSSSGGSSPQGLSSAESGIGAGDEHMKYLCPICEVVSATPHEFTNHIRCHNYANGDTENFTCRICSKVLSSASSLDRHVLVHTGERPFNCRYCHLNFTTNGNMHRHMRTHKQHQASQQQQQQPSQQQQTTQQQQQPQSQSQQQRRQQHAGGAGATGSGSGSAQLLTTRAESYESDASCSTDVSSELNSHSSNSNQSNHNNNNNSHKTNNNNNNNNNNNNNNNNEDELELEDEQLVLSNKQRRLKAALNNNNIIRDEEQENRVDDNSDVDSVESVAQVITSTPDVATLLASGGTSPTHSHSELHSPPLLQSCPACNSGEFESVPALCAHLDAEHGDIPAKCRECEVIYATHRQLQAHSCRGLPPLLGASSSPLHKQEESELEEQQQQHEEDHEQQHKQEEQEHAEQRECEDFFQQLYLKNKSSATLLPSPIKHEPADQRQDLADIQSILNMTSSSCTSSFLRNFEQSVNTPCSSQYSVDGRDGEEEAQDAFTNEFRRMKLRGEFPCKLCSAVFPNLRALKGHNRYHLSEVGAAGPFRCNMCPYAVCDKAALVRHMRTHNGDRPYECAVCNYAFTTKANCERHLRNRHGKTSREDVKRAIVYHPAEDASCEENKSRADADMLTELSGYRCPTPTEHSSSASSSSQLKHMLLAETTPAVKVTATAAAAVAATTSLPQQPLKIQVKSLDQLVDKPLPALDLSMDALDLSKKPAQLLAEQREQLERHELLLQQQHQQQQQQQQQQQQQQMFGAGDAAAQYMQQLLHSFMLQQAPGFPFFGFLTPPPPATTAAAADKSMPTNPAGAAGATAATIAAMPLSLPAGGPVKMVIKNGVLMPKQKQRRYRTERPFACEHCSARFTLRSNMERHVKQQHPQFYALRQRHRSGHHVMRERAASSNAVQAAAAAQAAAATAAAISNLSQQQQLQHSHSHHVHAPISEQVKYAILAQQLKARKDTDLLQQALAHGSSSVVANPLLHFSYNNNGNSNKQQQQQQLGNNTGNSLVMDDDEPPKLIIDEDDEDVEGEDDEDEEEEQEFDVDEDEQEDEEMDLDEEHQQQPHDEDDDDDDDDVDDDAAAAAATEASQQQLQPTKDKLQSKPIEAAKKVADTILEQAIKEREEKASEKQPHTQAKSLGNKPAAPTTMKTMIAQAESVAKSLKEVASSPFKDESQDLVPVAKLVDNATSNQVSFNSYFRPSDVANHMEQSDEEGLVASGSASESNNSGTEDVTSSSSSCGNDTKKKSAYSLAPNRVSCPYCQRMFPWSSSLRRHILTHTGQKPFKCSHCPLLFTTKSNCDRHLLRKHGNVESAMSVYVPTEDVSEPIPVPKSVEEIELEEQRRRQAAEAAQAEREQRERQKERERELELEREREQQHLIQQYRQQMAAAAAAAVAVAAVAVAAPAHPTPPQPAQSPPGLEASSDLPYKCHLCEFSFGERLQCLEHIKQLHAHDFALLLAKGAIETDAQLQQQQLPMAGGAPHSDDEAAAVGTRSGKYPDYSNRKVICAFCVRRFWSTEDLRRHMRTHSGERPFQCEICLRKFTLKHSMLRHMKKHSGRSHNGGELDHQSDCSDDEQLLPCSPPSTPTPTNNNNNNNTCQNNNNNNNNNNSNNNSNSKQVLRELLGKPNEWRVSRLGEHKENIAEATTTPSAATAAAAATAAAAAAAAAAAAVASGDLIGNLLGISDQGILNKLLSSPDEAAKLLGVEK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00535518;
90% Identity
iTF_00525357;
80% Identity
-