Dneu008392.1
Basic Information
- Insect
- Drosophila neutralis
- Gene Symbol
- ftz-f1
- Assembly
- GCA_035044385.1
- Location
- JAWNME010000381.1:475638-489563[-]
Transcription Factor Domain
- TF Family
- SF-like
- Domain
- zf-C4|SF-like
- PFAM
- AnimalTFDB
- TF Group
- Zinc-Coordinating Group
- Description
- The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 4 0.13 1.3e+03 -1.4 7.5 31 105 12 88 4 93 0.59 2 4 0.63 6.1e+03 -3.7 17.1 44 137 93 174 82 209 0.38 3 4 2.1e-19 2.1e-15 57.2 0.7 1 78 335 411 335 433 0.73 4 4 3.6e-72 3.5e-68 231.0 1.8 157 408 536 780 501 782 0.91
Sequence Information
- Coding Sequence
- ATGTTATTAGAAATGGATCAACAACAGGCGACTGTACAGTTTATATCGTCGCTGAATCTGTCGCCGTTTAGCATGCAACTcgaacaacagcagcccgCGAGTCCGGCGCACAGCAACACTAACAacgctaacaacaacaacaacaacagtaccagcagcaacaacaacaacaacaacagcagcagtaatagcaacaacaacaataacaacgataaCGATACAAATGCATTGAGCAATTCCGATAACGATTACAGTGCATACACTCTGCAACTGGGcagtcatcagcagcagcagcagcagcagcaacactcacATCACAcacatcaccagcagcagcagcagcagcaacaacaacagcagcattaccaacaacaacaacaacagaatattgccaacaacaatgcgaatgCAGCGGCGAACCAATTCAATGCTTCCTCCTATtcgtatatatacaatttcgATTCACAGTACATATTCCCGACAGGCTATCAGGAAACGAACTCATCGCATTCGCAGCAAAGTGCAAATGGAGCCGGCAATGCcgcagcaactggcaactctGGCCAGCTCCTGaacggtggcagcagcagctcgacaGGTAATAGTTACATGCTGTTGCCACCGGGCGCTGGTGGcacctctgctgctgccgctgcccaTATGTCCGGCAATGTGGGCGGCAATCCGGCCGCGGGCGTAAGTGGAACCGCTGCCGGCGGTGGCCATCATGGCGGCACCAGCGCCAGTTCTGGCGGCGGCGAAGCCATCGATTTTAAGCATCTCTTCGAGGAGCTGTGCCCCGTCTGCGGAGACAAGGTGAGCGGCTATCACTACGGCCTGCTCACCTGCGAGTCCTGCAAGGGCTTCTTCAAGCGCACCgttcaaaacaaaaaggtCTACACTTGCGTGGCGGAGCGCTCCTGCCACATCGACAAGACGCAGCGCAAACGTTGTCCATATTGTCGATTCCAGAAGTGCCTAGAGGTGGGCATGAAACTAGAGGCGGTTCGAGCGGACCGGATGCGTGGCGGTCGCAATAAATTTGGACCCATGTACAAACGGGATCGGGCGCGAAAACTGCAAGTGATGCGTCAGCGGCAACTGGCGCTGCAGGCGTTGCGCAGTTCGATGGGCACGGACATAAAGCCGACGCCCCTCTCGCCGGGCTATCAGCAAGCATAtccaaatatgaatattaagcAAGAAATTCAAATACCTCAGgtATCCTCACTCACACAATCGCCAGACTCATCACCCAGCCCCATTGCTATTGCCTTGGGTCAGGTGAATGCGAGCGGGGGCGGTGTGATAGCCACGCCGATCAATgccggcaatggcaacggtgGCTCCTCACTTGGCAATggcggcaatggcaacaacaacaacaccaacaacaacggcacAGGCAGCGGaagcggaggaggaggaggagggtcTGGTGGAGGAGGCAACAATActggtggcaacaacaacatcaccgATGGCCTGCAACGCAAtggaaacagcagcaatagcaacagcaacagcagttgccacGAAATCGGCACTGGATCTCTACAGAACTCAGCCGAAGCGAAATTGTGCTTCGATTCCGGCACACATCCATCGAGCACAGCCGACGCGCTTATTGAGCCACTCAGGGTCTCACCAATGATACGCGAATTTGTGCAATCGATCGATGATCGGGAATGGCAAACGCAACTTTTTGCGCTACTGCAGAAGCAGACGTACAATCAAGTTGAAGTGGATCTCTTTGAGTTAATGTGTAAAGTGCTTGATCAGAATCTATTCTCACAAGTGGATTGGGCAAGAAACACCGTCTTCTTTAAGGATTTAAAGGTTGACGATCAGATGAAGCTGCTTCAGCATTCTTGGTCCGATATGCTCGTGCTGGATCATTTGCATCATCGCATTCACAACGGTCTGCCCGATGAGACTCAGCTGAATAACGGTCAGGTCTTCAATTTGATGAGTCTTGGTCTGCTGGGTGTGCCACAGCTGGGTGACTATTTCAACGAGCTGCAGAATAAGCTGCAGGAACTGAAGTTCGATATGGGCGACTATGTTTGCATGAAATTCCTAATACTGCTAAATCCAGATGTGCGAGGCATTGTTAACAAGAAGACCGTCTTGGAGGGACATGAGAATGTTCAGGCCGCGCTACTGGATTACACACTGACCTGTTATCCCTCAGTTAATGACAAATTCAGGAGGCTACTTAACATCCTTCCGGAAATACACGCAATGGCCGCACGAGGCGAGGAGCATCTCTACTCAAAGCATTGTGCTGGCAGTGCACCCACACAGACGCTGCTCATGGAGATGCTGCATGCCAAGCGGAAAGTGtaa
- Protein Sequence
- MLLEMDQQQATVQFISSLNLSPFSMQLEQQQPASPAHSNTNNANNNNNNSTSSNNNNNNSSSNSNNNNNNDNDTNALSNSDNDYSAYTLQLGSHQQQQQQQQHSHHTHHQQQQQQQQQQQHYQQQQQQNIANNNANAAANQFNASSYSYIYNFDSQYIFPTGYQETNSSHSQQSANGAGNAAATGNSGQLLNGGSSSSTGNSYMLLPPGAGGTSAAAAAHMSGNVGGNPAAGVSGTAAGGGHHGGTSASSGGGEAIDFKHLFEELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNKKVYTCVAERSCHIDKTQRKRCPYCRFQKCLEVGMKLEAVRADRMRGGRNKFGPMYKRDRARKLQVMRQRQLALQALRSSMGTDIKPTPLSPGYQQAYPNMNIKQEIQIPQVSSLTQSPDSSPSPIAIALGQVNASGGGVIATPINAGNGNGGSSLGNGGNGNNNNTNNNGTGSGSGGGGGGSGGGGNNTGGNNNITDGLQRNGNSSNSNSNSSCHEIGTGSLQNSAEAKLCFDSGTHPSSTADALIEPLRVSPMIREFVQSIDDREWQTQLFALLQKQTYNQVEVDLFELMCKVLDQNLFSQVDWARNTVFFKDLKVDDQMKLLQHSWSDMLVLDHLHHRIHNGLPDETQLNNGQVFNLMSLGLLGVPQLGDYFNELQNKLQELKFDMGDYVCMKFLILLNPDVRGIVNKKTVLEGHENVQAALLDYTLTCYPSVNDKFRRLLNILPEIHAMAARGEEHLYSKHCAGSAPTQTLLMEMLHAKRKV
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00485910;
- 90% Identity
- iTF_00553087;
- 80% Identity
- -