Basic Information

Insect: Drosophila neotestacea
Gene Symbol: -
Assembly: GCA_035044365.1
Location: JAWNMD010000270.1:2157216-2161292[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 0.04 3.1 8.6 0.0 1 23 372 397 372 397 0.95

2 17 0.31 24 5.8 3.5 3 19 409 425 408 427 0.93

3 17 5.9 4.5e+02 1.8 3.0 2 17 440 455 439 466 0.75

4 17 0.017 1.3 9.8 0.9 1 23 497 519 497 519 0.94

5 17 0.00029 0.022 15.4 3.6 1 23 527 550 527 550 0.98

6 17 0.0019 0.14 12.8 0.2 2 23 555 576 554 576 0.97

7 17 2.7 2.1e+02 2.9 0.1 1 20 584 603 584 605 0.88

8 17 0.00026 0.02 15.5 1.1 1 22 624 645 624 648 0.90

9 17 0.28 21 6.0 0.9 3 21 655 673 655 674 0.90

10 17 0.0073 0.56 11.0 1.0 1 23 693 718 693 718 0.96

11 17 0.012 0.93 10.3 1.4 2 23 734 756 733 756 0.93

12 17 0.0044 0.34 11.6 0.5 2 23 762 784 761 784 0.92

13 17 0.05 3.8 8.3 0.2 2 23 788 810 787 810 0.95

14 17 6e-05 0.0046 17.5 2.0 1 23 816 838 816 838 0.98

15 17 0.012 0.91 10.3 1.1 1 23 842 865 842 865 0.93

16 17 4.5e-05 0.0034 17.9 0.8 1 23 871 894 871 894 0.97

17 17 0.013 0.98 10.2 0.2 5 23 907 926 899 926 0.90

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	0.04	3.1	8.6	0.0	1	23	372	397	372	397	0.95
2	17	0.31	24	5.8	3.5	3	19	409	425	408	427	0.93
3	17	5.9	4.5e+02	1.8	3.0	2	17	440	455	439	466	0.75
4	17	0.017	1.3	9.8	0.9	1	23	497	519	497	519	0.94
5	17	0.00029	0.022	15.4	3.6	1	23	527	550	527	550	0.98
6	17	0.0019	0.14	12.8	0.2	2	23	555	576	554	576	0.97
7	17	2.7	2.1e+02	2.9	0.1	1	20	584	603	584	605	0.88
8	17	0.00026	0.02	15.5	1.1	1	22	624	645	624	648	0.90
9	17	0.28	21	6.0	0.9	3	21	655	673	655	674	0.90
10	17	0.0073	0.56	11.0	1.0	1	23	693	718	693	718	0.96
11	17	0.012	0.93	10.3	1.4	2	23	734	756	733	756	0.93
12	17	0.0044	0.34	11.6	0.5	2	23	762	784	761	784	0.92
13	17	0.05	3.8	8.3	0.2	2	23	788	810	787	810	0.95
14	17	6e-05	0.0046	17.5	2.0	1	23	816	838	816	838	0.98
15	17	0.012	0.91	10.3	1.1	1	23	842	865	842	865	0.93
16	17	4.5e-05	0.0034	17.9	0.8	1	23	871	894	871	894	0.97
17	17	0.013	0.98	10.2	0.2	5	23	907	926	899	926	0.90

Sequence Information

Coding Sequence: ATGTTGTCGGAAAATtcgaaaacaaataaagaaacttTGCGTTTCTGCTTGCATTGCAAAGTGCACAATTCAAAACAGCCATTCCAGGAGATATTCGATGAAGTGGGAATTGAAATCGAGCTGCCCCAATTGCTGGCCAAGTATTttcagataaaaataaaacctgATCCACAGAAACAGCAGCTACTTTGCCAAGAGTGTGTCAAAACTTTAATACGTTTCTTTGACATTGATGAACTGCAGCGGGAACAAGATGCGGCAAATGCTGCTAAACAGAAATCCAAAACGCAGGACAAAACTGAGACGCCACCTGCGAGTGTCGCTCCTAAAATTGAAACAAGGTCATCTAAAAAACCGACACCGCCAGCGATCCAAGCTAAGAGTGAACCTAAAAAATCGACTTCTACTATAAAGTTGGCCACAAAACCGACGCCAGCACCTCCTGTTCCTGCAGCAAAATCAATACCACCGCAAGAGCCAGTTTCCATACGCATCACCAGAGGAAAATCTATGGCTGTGGCCTCAAAAAGTGACCAGATCAAAGCCAAGCCGAAAACAGTTGAAAAATCAAGAGGGAAACCCCGTAGATCCAAGGAAACCCGACCGGGGGAACAGGAGCAGATAAGTGACCTCTTACGTGATATTTTGGATGATGAGAAGGCGCCACCTGACGACAAATTCGCCGAAGCTGCTGCAACTGTGCGTCAGCTGGAGGAAACTCATGTTGCTGCGGAGGAAAAACAATTGCaggaagatgaagatgaaaaaCAACGGGGAAATACTGCTGAGCTGGAGTATCTGCTCGAGCATGAAGATGGTTCCTCTGACTTGGATGCGCGTCACTTTAAAGTAGAGAAAACTACATCAATTGACACCTCACAGACGCAAAGCGAGGATGAATCCTTCAAAGTGGAGCcctttaattttgtattgatCAAGGAATCTGATGACATTGATGATCTGTATGAATACTTGGCCACTGTGGTAAAGACTTGCTTTGAGACCTTGACCTTTGAATGGGCCACCGTGTGTTGTCACTGCTCGTTGAAGTGCAGCAAATTTGAGACATTGTTGTGGCACATGCAAAAGTGCCACAAGCTACCAGAGGAACGCTACAAGTGCCCTATTGAGGATTGCAACGCGGAGTTGACCAATCGCAAAGCCTTGGCCATGCATCTGGTCGTGTTGCATGCCCCTGTGGCAGACATTCCCATTTACGGCTGTTGCCCCGAGTGCAACATGACTTTTTCGAATATCTTGCAATACAATAAACACTCCTGTGCCCGTGTCATCAAAAAGCGTCGTGGCATACGCTTGTATTGCGAAATGTGCGGCTTGGAGTTCCCCTCCTGGAAGCGcttCAACTTTCACAATCAGTTCCACTTGGAGAGGCACAGACCTCGTGCTTGCTTTGTATGCAACTATACCGACAACAACATAGATGATCTTTTCCAGCATTTGCATTATTCACACGAACCCGAAGGCACGCACTTCTGTGATATCTGTGATCGCAATTTCCGCGACGCTGTTGTGTTTGCAGAGCACAATAAATCTCATACGAATGTCACCAGCGCCACATATAGCTGCAACCATTGTCATGCCACCTTTGAGACACGTGGACGTCTCAATGGTCACATTcGCACCTCACATGGATCCGTCATAAGCTGTGAGCTGTGCAGTAAGGAGTTTGCCACAGAGGCCACATACAACATTCACGTGAAGAAGCATCTGATCATTGAGCTTGAGGTGCATGTGTGCAGCAATTGTGGACAACTCAGCGACAATCCTGATAAGATGGTGACTCACGTCGAGAATGCTGCTTCTGATTGCTTTGGCGTTGAAGTCTATGTGGAACAACTTCGGGATGCCTATGTTTGTGAATATTGTTCGACATACTTTAAACAGAAAACTGATTTGCGTACTCATCGGGATTCGGGTGTACACAAGGATGGTATCTTCTGGTGTCAGCCGTGTGAAAAGGGGTTTAATGACATGAAACTATATCGTCATCATATGCGCAActatcaacaacaacgttcGGATGTTGATCATCGCAAACTAGAGATTTGTCTGTACTTTATGTGCGACTATGAGGATTGTTTTGAGTCGTACATCAATTGGAATTCTTTGTACACGCACAAGCGACGCACTCACGATGCGGTCGATAAGCTGGAATCAAAGTCAAAGGTCAACGAATGGATTTGCCAGTTCTGTCAGAAGGTTTGTCGCTCCAAAATGTCGCTATCGGTCCATGTGGCACGCAGTCACAACAACAATAATGTTGTTTGTAAGCTCTGCAAGGCATCGTATAAGGATGAGGAGGCGTTAAAGAAGCATCATGCCTATTGGCATGAGCCCATGGAGTGTGCACTGTGCCTAAAAATTGTCAAGAATCGTCGCAACTTTGACACACACATGAATGTGGTTCATTCAAATAACAAACGTTATACCTGCAGTGTCTGTGAGAAGGGATTCTATCACAAAAGCGAAATGGAGGCACACAAGCGAttgcattcACAATTGTTTAGCTGCGATCAATGCAGCTTTACTACTAAGAAAAAATCTTCACTGTCGGTTCATGTTCTTGGCCAGCATTTGAAGAGTTACGGCTTTGAGTGTAAGAGCTGCAATAGGAAATTTGGACGTCCTCAGGGCTTAAAGAATCATATGCTACGTGTTCATGGATCCAAGAATACGTGTCGTGATTTCTTTGAAGCTGGTTGCAGCAAGTCTTTTGGCACAATCGCACAACTAAACGTGCATGTTCGTAAAGCACATAATGGCAATCTTTTCCAAACCGATGTTGACGAAGACGAGCAGGAGAaccaggaggaggaggaggaaccGGACCAGGAAGAGCAAGAACAGGATCAGAAGCCACCACAGGAACAAAAACCGAAGCTTGAGGATCCATCACCAGCATCAACATCGAAAAAACGTTGCATTCGCATCAGCGATGATACACAGATCGAGATTATTAATGCCGAGCACGAGGAGAGTAACAAAAGCATAGCGGACTCGGAAACTTTGGAGGAGTTccaaaaaactaaatgcaaACCGCCCAacccaaaaagaagaaaaaaacaaacttaa
Protein Sequence: MLSENSKTNKETLRFCLHCKVHNSKQPFQEIFDEVGIEIELPQLLAKYFQIKIKPDPQKQQLLCQECVKTLIRFFDIDELQREQDAANAAKQKSKTQDKTETPPASVAPKIETRSSKKPTPPAIQAKSEPKKSTSTIKLATKPTPAPPVPAAKSIPPQEPVSIRITRGKSMAVASKSDQIKAKPKTVEKSRGKPRRSKETRPGEQEQISDLLRDILDDEKAPPDDKFAEAAATVRQLEETHVAAEEKQLQEDEDEKQRGNTAELEYLLEHEDGSSDLDARHFKVEKTTSIDTSQTQSEDESFKVEPFNFVLIKESDDIDDLYEYLATVVKTCFETLTFEWATVCCHCSLKCSKFETLLWHMQKCHKLPEERYKCPIEDCNAELTNRKALAMHLVVLHAPVADIPIYGCCPECNMTFSNILQYNKHSCARVIKKRRGIRLYCEMCGLEFPSWKRFNFHNQFHLERHRPRACFVCNYTDNNIDDLFQHLHYSHEPEGTHFCDICDRNFRDAVVFAEHNKSHTNVTSATYSCNHCHATFETRGRLNGHIRTSHGSVISCELCSKEFATEATYNIHVKKHLIIELEVHVCSNCGQLSDNPDKMVTHVENAASDCFGVEVYVEQLRDAYVCEYCSTYFKQKTDLRTHRDSGVHKDGIFWCQPCEKGFNDMKLYRHHMRNYQQQRSDVDHRKLEICLYFMCDYEDCFESYINWNSLYTHKRRTHDAVDKLESKSKVNEWICQFCQKVCRSKMSLSVHVARSHNNNNVVCKLCKASYKDEEALKKHHAYWHEPMECALCLKIVKNRRNFDTHMNVVHSNNKRYTCSVCEKGFYHKSEMEAHKRLHSQLFSCDQCSFTTKKKSSLSVHVLGQHLKSYGFECKSCNRKFGRPQGLKNHMLRVHGSKNTCRDFFEAGCSKSFGTIAQLNVHVRKAHNGNLFQTDVDEDEQENQEEEEEPDQEEQEQDQKPPQEQKPKLEDPSPASTSKKRCIRISDDTQIEIINAEHEESNKSIADSETLEEFQKTKCKPPNPKRRKKQT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00583895;
90% Identity: iTF_00608656; iTF_00583895;
80% Identity: -