Basic Information

Insect: Drosophila neotestacea
Gene Symbol: -
Assembly: GCA_035044365.1
Location: JAWNMD010000757.1:2761422-2764597[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 16 0.00023 0.018 15.7 5.8 1 23 168 191 168 191 0.97

2 16 0.0034 0.26 12.0 2.5 1 23 239 262 239 262 0.97

3 16 0.00064 0.049 14.3 3.3 1 23 328 351 328 351 0.96

4 16 0.0031 0.24 12.1 0.4 2 23 403 424 402 424 0.97

5 16 3.3 2.5e+02 2.6 0.5 1 19 537 555 537 558 0.72

6 16 0.02 1.5 9.6 0.6 1 23 567 589 567 589 0.94

7 16 0.00026 0.02 15.5 0.6 1 23 596 619 596 619 0.96

8 16 0.00036 0.027 15.1 1.4 2 23 627 648 626 648 0.96

9 16 0.0027 0.2 12.3 0.0 3 22 676 695 674 698 0.89

10 16 0.002 0.15 12.8 1.6 1 23 735 758 735 758 0.96

11 16 0.63 48 4.9 1.6 1 22 765 786 765 786 0.97

12 16 0.0018 0.14 12.9 0.9 1 23 795 818 795 818 0.96

13 16 1.6e-05 0.0013 19.3 0.5 1 23 837 860 837 860 0.97

14 16 0.099 7.5 7.4 0.2 1 23 870 892 870 892 0.94

15 16 5.1e-05 0.0039 17.7 3.1 1 23 898 920 898 920 0.98

16 16 5.3e-05 0.004 17.7 0.9 1 23 926 948 926 948 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	16	0.00023	0.018	15.7	5.8	1	23	168	191	168	191	0.97
2	16	0.0034	0.26	12.0	2.5	1	23	239	262	239	262	0.97
3	16	0.00064	0.049	14.3	3.3	1	23	328	351	328	351	0.96
4	16	0.0031	0.24	12.1	0.4	2	23	403	424	402	424	0.97
5	16	3.3	2.5e+02	2.6	0.5	1	19	537	555	537	558	0.72
6	16	0.02	1.5	9.6	0.6	1	23	567	589	567	589	0.94
7	16	0.00026	0.02	15.5	0.6	1	23	596	619	596	619	0.96
8	16	0.00036	0.027	15.1	1.4	2	23	627	648	626	648	0.96
9	16	0.0027	0.2	12.3	0.0	3	22	676	695	674	698	0.89
10	16	0.002	0.15	12.8	1.6	1	23	735	758	735	758	0.96
11	16	0.63	48	4.9	1.6	1	22	765	786	765	786	0.97
12	16	0.0018	0.14	12.9	0.9	1	23	795	818	795	818	0.96
13	16	1.6e-05	0.0013	19.3	0.5	1	23	837	860	837	860	0.97
14	16	0.099	7.5	7.4	0.2	1	23	870	892	870	892	0.94
15	16	5.1e-05	0.0039	17.7	3.1	1	23	898	920	898	920	0.98
16	16	5.3e-05	0.004	17.7	0.9	1	23	926	948	926	948	0.98

Sequence Information

Coding Sequence: ATGACGAGGACATGTAGAATCTGCGGTGGGGCAGATGGACGCTTTTGGATTGAGACGCCAGTCGATAAATATGCAGAGAAAACGTTCAATCAACTACTGTCAGAGCTAACCAGACTTGAGGTCGCTTTGGATCAAGCTGACAAGCTCCCGCCCTGGCTTTGCCGAAGCTGTGCACAAAGATTGGAAAATGCATATGACTTTGTCCTGCAAGCGCGTGAAAGTCACAAGCTTTGGATCCAGAAACTTTCAACAGAATCCGCTCTGGATGACGCTGAAAAAGCGACTTTAGAATGTCTGCGAGAGACTCCAATACAATTGCTGGAGATTGAGggaattacaattaaaatggaaGAGCCATCTGAACCTGCCATGCTCCAAGCTGATCCAACGATATCGGTGGATCCCCTTATTAAGAAAATACTGGATGATGGtagcgatgatgatgatgacgatgtgCCGCTGAAGCAACGCAAAGCTAATTACGCTAAATTACCAATGCTACACAAGTGCAATAGGTGCGACAAAACCTTTAGATATGTAACAAATCTCTTCAGGCACAAGCAGCGGGATCACAGTCCTGTTCGTAAGATCACATCAAAAGGGGAAAGAGAAAGTGCTGACTCCACAGAGCCATTCCTAAAAAACCTCATAAAGAGCTCTTTGGTAGCCCAAAGCAGCGCTAATTCCGACGTGGACAGTGAAGCTGATAACTACTACAAATGTGATCAATGCGACAAATCCTACAAGTACATAATGGTCCTGATCAAGCATAAGCACACGGCCCACGGCGCCAACCAGTTGCCAGCAGAGCCAAGGCCAATTCGAAGAAGTGAATCGAGTTTAGAACAAACATCTACAGTTAAAACAACTCAGCGTCAACGCTCAAAGCCCCCCAGCACTGACTCCCTGGTGCACAGTCTCATCAAAGAGGTCAAAACACCTGAGGAGGATGATCAAGATAACACAGGTGTCGACAATTACTACAAATGCGATCAATGTGACAAGTCCTACAAATATATTGTGAGTCTcatcaaacacaaacacaaggAACACAATGCGTACAAAGATAccgatgaggatgaggatgaagcATCTTCATCAACATATGCAACAGGAACACCTTCAATGTCAAAGCCTTCACGCATCGATCGAAGGGTCAAAAGCTTCGATTTGCATCGCTGCAAACCGAATGGTTCCAAGGAGATTCAATGCATGATCTGCCTGCGAAGATTTGTTAAGCTAAGAGAGCTACGCGATCATCTCAGAGCACATCCCAGGGATTTTAATTTTGACGCTCACGGCGAACCCATTGAACGTATTGCTGAAGGCTTTTACAGGACAGCCGTGGAATCAACGGCTGCCGGCTTGAAAATGCGTATTTTAAATGATCTCAAAGTTGGCATGTTTGGCCGATATTATTCCATAACCAATGAGGCACGTTACGAGATGAATCTGGACAGCTCGGATACGGACAGTGATGGCGAGGCGGGAGTTGTTCAACGACGTAGTTACGCCTGTGAGCTGTGTGATTCGCCAACTGCCGTTTGGCCACGTAAATTCCAACTGCATGAGCATCATCGTCAGCAACACACTTGGCTGGAGGCACCTTACGTCTGTCAGCGCTGTGATTCCCGATTCCTAAGCGCGCAACTACTCGACCATCATACGGAGAAACTTTGCCAGAACACCCTTAAGCGTTTCATGTGCGACAAGTGTCCGCAGCGATTCTTCTGGCGGCGGAATCTGCGTGCACATCTCGTTGAGCATAAAAACAAGCAAGAGAATTACCCATGTGATCAGTGCTCACGGAGTTTTCAGGATAAAAGTGCCGTGACGAAACATAAACTTATGCTTCACGATACCAGCAATGAGTTGATACCTTGCCGTTGGTGTACAAGGACATTCTATCGCCCTGCTTTGCTGCATAAGCATGTAAAGCGTCATGGCTTCAGTGGAGAGGATTTGCCCCTGGCAGAGACATTGCTGGCTGATGCCGCCAAGCCATCTGGACCAAAGACAATCATATGCAAGCTATGCGATATGCAGTTTGTTAGCATAGCCGATTTGCGAAGACACATTTCAATCCAGGCTCACAGCGAGGAGGTTTGTAATTACATGATAAGCACAGAGGATGGATTCGAGTTGCAGCTGGATGAGACGGACGATAGCGATGATGAGACCACTGGTTCTGCTGGCAGATCCTACAGGTGTAATCTCTGCGATATGACCTTCCAGCGTCGTAGGGAAATGAGCGAACACCAGTATTCCTTGCACACCTTTGATAAATTACCATATTCCTGTGAGCATTGCATTTACAAGACAGTCGATAAGAACATGCTGGACCACCACTTGCGTACACAGTGTCTGAACCAGGAGAAGAAATTCAAGTGTACGCGTTGTGGCTACAAATtcatgtggagtgaaaatctAGAGCAACATATGGTCAGTCAACATTCCAAATCGTCCAATCAGACGGCCGTTACGACCAAGCGAAGTCGACGCTTTAGATACCAGTGTCCGCATTGCTGGCGATCTTTTGTTGTCCAACCCAGTCTGGACAAGCACATACGGGACATGCATGTGGCCAAAAAGAATCCGGGCAAAAAGTATCTCTGTTCCTTATGCGGTCTAGAATCGCTCACCCCTAACAAGCTCAGCATCCACATGCGTCGCCACAATGGCGAGAAACCACACAAATGCGATCTCTGCGACATGTCCTTTACAGTCTACTACGAGTTAAAGGTTCATCGCCGAAAACATACGGGTGAACGACCCTATCAATGCACTTTCTGTGCCAAGGACTTTGCTCGTCCGGATAAGCTAAGACGACATGTTTACATGCACAGTGTTAAGCGTTAA
Protein Sequence: MTRTCRICGGADGRFWIETPVDKYAEKTFNQLLSELTRLEVALDQADKLPPWLCRSCAQRLENAYDFVLQARESHKLWIQKLSTESALDDAEKATLECLRETPIQLLEIEGITIKMEEPSEPAMLQADPTISVDPLIKKILDDGSDDDDDDVPLKQRKANYAKLPMLHKCNRCDKTFRYVTNLFRHKQRDHSPVRKITSKGERESADSTEPFLKNLIKSSLVAQSSANSDVDSEADNYYKCDQCDKSYKYIMVLIKHKHTAHGANQLPAEPRPIRRSESSLEQTSTVKTTQRQRSKPPSTDSLVHSLIKEVKTPEEDDQDNTGVDNYYKCDQCDKSYKYIVSLIKHKHKEHNAYKDTDEDEDEASSSTYATGTPSMSKPSRIDRRVKSFDLHRCKPNGSKEIQCMICLRRFVKLRELRDHLRAHPRDFNFDAHGEPIERIAEGFYRTAVESTAAGLKMRILNDLKVGMFGRYYSITNEARYEMNLDSSDTDSDGEAGVVQRRSYACELCDSPTAVWPRKFQLHEHHRQQHTWLEAPYVCQRCDSRFLSAQLLDHHTEKLCQNTLKRFMCDKCPQRFFWRRNLRAHLVEHKNKQENYPCDQCSRSFQDKSAVTKHKLMLHDTSNELIPCRWCTRTFYRPALLHKHVKRHGFSGEDLPLAETLLADAAKPSGPKTIICKLCDMQFVSIADLRRHISIQAHSEEVCNYMISTEDGFELQLDETDDSDDETTGSAGRSYRCNLCDMTFQRRREMSEHQYSLHTFDKLPYSCEHCIYKTVDKNMLDHHLRTQCLNQEKKFKCTRCGYKFMWSENLEQHMVSQHSKSSNQTAVTTKRSRRFRYQCPHCWRSFVVQPSLDKHIRDMHVAKKNPGKKYLCSLCGLESLTPNKLSIHMRRHNGEKPHKCDLCDMSFTVYYELKVHRRKHTGERPYQCTFCAKDFARPDKLRRHVYMHSVKR

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00806138;
90% Identity: iTF_00528986;
80% Identity: -