Basic Information

Insect: Drosophila neoperkinsi
Gene Symbol: ZNF541
Assembly: GCA_037043555.1
Location: JBAMBG010008411.1:27463-41050[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 5 0.00012 0.0091 16.4 0.2 2 23 355 376 354 376 0.97

2 5 3.9e-06 0.00028 21.2 1.3 1 23 382 404 382 404 0.98

3 5 0.0012 0.091 13.3 2.4 1 23 410 434 410 435 0.93

4 5 0.00059 0.043 14.3 0.8 2 23 699 720 698 720 0.97

5 5 0.0018 0.13 12.8 0.1 1 23 1819 1843 1819 1843 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	5	0.00012	0.0091	16.4	0.2	2	23	355	376	354	376	0.97
2	5	3.9e-06	0.00028	21.2	1.3	1	23	382	404	382	404	0.98
3	5	0.0012	0.091	13.3	2.4	1	23	410	434	410	435	0.93
4	5	0.00059	0.043	14.3	0.8	2	23	699	720	698	720	0.97
5	5	0.0018	0.13	12.8	0.1	1	23	1819	1843	1819	1843	0.98

Sequence Information

Coding Sequence: ATGGCTGCCATAAATACGGTATCCAAAAGCATACATCTGCCTCTGACGAATCTCAGCGCTCAGCGTGTGTTGATGTGCAGCGCCTCTCTGGGCAGCGAGGGATCCGTGACACTGCAACTGAGAGATGCGAGTACCTTGGAGACAGCCGATagcacaacaccaacaacaacaacaacatcgacatcagcaacagcagcaacaacaacaacatcaaatccAATAGCAACATCGTCATTGAGCAGCCAATCAAATGGCGTCACAGTGCTTGAGACATCGTCATCAGCTGCGTCAGGAATAACGTCAGCATTAGAGAATGCGCTGACCGTTGGCTATCCGGATCCGGAAATGCTAGCAGATGTTTTAGGCACCATACAGACAGCCTctCTTAAAAACAAgcatagcaacaacagtaataatagcaacaacaacaccagcatcaaaagaagcaacaacaacaagagcagcagcactgcAGCGACAATTCTGAACAGCTCCGGGATACATCTGAACAGTCCCAATAAAATAACGATAACACGTCGCAGTGCCAGCAACAAGATTAGCGTACAGACTGTGAGCACATCGACGAACACAACGATTAGCAGCATTGGCGGCAGCAAGACCAACTACATTAAGAACTGTCTAatacgcagcagcagctgcagcaacacgGCCACCAATGTTACAACGTTGGCACAGATTCTGagtaacagcagcaccagcagcgcaGCCAGTTTACTCAgtcagcacaacaacaatagcaactgcagcaacagcagcaactttagCATCGCATCCTCTGTGGGCAGCATTGgcagcgtcagcagcaacaccagcaataccagcagcagtagcaactgtagcagcagcaatagcaacgatagcaacagcagcatcggTCAAAGTTTAAGCTTCAAGAGCAATGGTCGAAATGTTGCTGGCATAGTTACTGCATCAACAACATCGAcgagcacagcagcaactggcattggcattgtcaCCGTCGACAACGCGCCCAGAAAGAGTCGACCCAAATTATCCTCCCCTACGCGTCACGGACCACAGCAGTGTCAGaTTTGTAGCAAGATCTTTGGAAATGCCTCGGCGTTGGCCAAGCACAAACTGACGCACAGCGACGAAcggaaatatatttgtgcgcTCTGCTCGAAGGCATTCAAGCGGCAAGATCACTTAAACGGACACATGATGACGCATCGCAACAAGAAGCCTTACGAGTGTCGAGCGGATGGTTGTGGCAAATCATATTGCGATGCGCGCTCCCTTCGTCGTCATTCGGAGAATCACCATGGATGCGTGCCGACCAGCGAATCACTCTCGCCAACGGCCAGCACCAACGGCAATGTCAGCAACGGCACCGGCAGCGTCATTGGCAGCgggagcagcagtagcagcagcaacggcatcGGCGTTGCCACCAGTTCCCTAAGCCTATCGCCGGCTACGGCCAGCGGAGATGCCAGTTCACCGGATGGCGCCACCTGCATTCGCACATATATTTCCACTGGTAGCTCCATTGTGGATGCGGCCACTGGAATTGCGCTGTCGGATGAGCAAATCAGGGCAATGAATTTGCCCATCAAAACAGGTGTTACTCTGCTCTCGCCCACCACATCGACATGCTCGACAACATCTTCCACCGCATCCTCTATGTCATGCTCGTCATcgggcaatggcaacggcagctCCATTGTGGCCAGTTCACCCACCATAACGCTCTGTGATGGCGCAACGCTGGAGGCCGAGGGACTCACACGCGAGCAACTCGATCTCATCAGCAAGATCATGCAGCAGACGAAGCAAACCAGTGCCCAGGTCACAGTCTCGTCGCCCACCAGCGTTAGTTCCTATAAAATCAATACGGAAACAGCCCAAGTCTCGGCGCGACCGAGGACCTGGAACATGCAATTGCTCAataatgtgcaaaatgtgACGCTTACAGTGGACGAGGGTACCGAATTGGTTGCCTCCGCATCAAGCCCGCCCGACGAGGTAAAGGACGATGAGCTGGGCCAGCAACAGCTAGTGGCCGCCATAAATCCCCACCTGCTCAACATTGTGAAGGTCGACAAGCCAGTTGAGTGTAATCTCTGTCACCGTAAGTTCAAAAATGTACCCGCCCTCAATGGGCATATGCGTCTGCATGGCGGCTACTTCAAAAAGGATCCGGAGACGAAGCGCAGCGAGAAAAAGGACTCCGGCGGACCTCCCCTGCAGACGGCCAGCATTGGGGTGCGTGCCCTCATCGAGGAGAAGATTATAAGCAAGCGCAAGGACATCAATAAGGGTGCCTTCGCAGTTCCTGCACCACCCAGCAGTGCGGTTAATAGTGGTGTCGTCagctgcaacaataacaataacagcagcaacagcagcaacaacaacaataacaacaggaATTGCAATCTGCGTCGCTCCATCAGCGACTTGGAGAGTTTTCTCAGTCCGAAGAGCAACGCGAACTGTAGCCTGAGCCAAGCGCTAGCCACCACTTGCAgcaccaccacaaccacagcGGTGCTGCCTGCTGCAACCACCATTAAGAGCAGCAGTGGTTTAAGCATTCAACAGATTGGCCTACCGCAAAGCATCGAGATCTTCAGCGGTGGGCAGCGACAGCCGAAAACTTTGAGTTTGGGCAGTGGTGCAAATACGATTACGATAACCACCAACAATGTGCctacgacgacgacaatgaGCGCTCTGTCGGCACTAAAGGGCGCCAGCAGCATTAGCAGTGTCTCTGGCAATGCGGATCCCAAGGATTCCACATTGATTGAGCTACTCAAGCGTGGCACGAGGATTGCCGTCACCTCGAAGAAGGCACAAAACACAAGTACAAATCTGCTGCTCAGCAATGCGGCCAACGCCGAACTCATTGGCAGCAGTATCCAGGCAGCGACTAGTCGTCAGATTatcaccaacaacaatcgcaCAGTGATTATACCCTCGGATGTGCATGTCGTGTCCACAAAGTCCAACAAGATGAGCAGCAACGGAGCAAGCAATGCGAACAGTATCTCTCTGCCGGATGGCACACCACTCTCACTGACCATTGGAGGTAATCAGGAGAGCATTGGGCCAAGCAGCATCTCGGGTGGTGTCAATGGGGTTTATGCGGTCACCTACACGACTAATACGGATGCAGTTGATCTATTTGGCAATGCCGAGGTGTTTAATGTCTCGGATACGGAAATGCTATTGCAAACTGTGGACACAATGGAACTGATGAACAATGAGGAAGAGAATGAGGATGAGGGGCACAAGCAAAGCGAACATTCCGGGAACTTTCCGCTGCTCAACAGTGTTGAGGACGATGTGCTAATTAAATTGGAGCCAGAGTCGGGCACACCCaataccaacaccaacacaaacaccaaCCCTAATCAGACAACAACGCCGTTGCCCACGTTCCAGCAATTCCATTCCAAGGAGCTCATCATGCAGAACAGCTCACAGATTCAGGCGATTGCCAATATGCGAGGAGGTGTTCTCTCATCACCATTGCATTCGCCATTGGCTTATCCGACACCGCCGTCCAGTCACGAGAATGTTGCTCAATCCTCGCCATTTATTGAAGATGCTGCGGCTCAGTTTGTGGACGCCAACCACACGTTCTTCGGGGATAAGACAGATTTCTCGCACGTCTATTTCAAGACGGATGACGAttgcatgcagcagcagctcagtgAGAATGACAATGAGAAGATACTCAAATTAAAGACGGTGCTGGAGGAGAGCGCTTTTGATGCTTCGATCAAGGTGGAGGATCTCTTAAATGGCACCGAGGATGATGCTGAGTGTGATCTGCGTGAGTTTGCGGAAACTAATTTGTCGTTTCTCGATGAGGATCAGGAGTTCCTGAATGACTCACGCAATGCCACCTCACCTCTCTCAGAGTCCTTTTTCACCAGTGGCATTGGTTCCGCCGAGGATGTTAAGCAGGTGCTTCGCGAGGTCCTTCCAGATGAGAatatgcaattgcagctgagCAGCGAACAGCTGGCTGAGAATATCATCGATCTCTACTATTTGCCCGGATTGGGACTGCAATCGCAAATGATGTCCAACTCGGATGATCCGCTCTTGTCCTCTTCTCCCCGAGATTTTGGCCTGCAACGTCAGGTGGTCCATGCGACGACGTCGGCAACTTCATCGACTGTACCGACCATGGAGCAGTTGCAGTCTTCCGGGGTCATGTtcgagcaacaacagcagcaattgcagcctcaacagcagcaagtggAGCGGCAAGAACTGCaacctcagcagcagcagcaacagttagGGATCgggcaacagccgcagcagcagcaacagtcggaCTTTATGCTGTCAAACTTTACGCCCGTGTCCTGTCAAACGCAGTATTTGGACGCCAATCAGCAGTCGATGACAATGCAGCCGCTCAACAATCTGCTGCAGCCATTACTCTtcggcagcaacaatagcagcaacaacaacaacaacagcatcgatAAGCAACAAGAGTTTGGAACGCTGCTGCAAACTACAAACGGTCAAACATCCGCTTTGGATGCTAGCCTGATCTTTGCCTGCGGCGACGGAATCAAAAGTAattccaacaacaataagtcGCTGATTGCCAACTTACCCGCAGCAGCTCCAGTGGCGACACCATCACCCAGCTTTTCCAATCTGCAACCGTTGTCCAATCAAACGAATTCCATATTGAAGCGTCGCCTGCGCTCAAATGGTGCACAGGATGTGCACAAGTTCTCCAAATTCCATACGCTATCGCCACATCGCTCCAAGCTGCGCAAACCCTCGCGCACCCACTACACTCCGGCGCCAATATTGAATCCGGATCGGAAGGGCACCGGACTCTATTACAGTGTACGCAAGCAGCTTGGTCAGAACATGTTTGATGCCTTTGACGATGATTTTGGTGATCCCGTGGGCCTGGTGGACTTCTCCGACGAGTCCAAGGTGAATCTGGGCTCGACGTATCAAGCGCAGATACCCGCCTGCAAGCCACTCGAAGAGGCCATCAAGGAGACAATGTGCGCGGACATGATGTGGGATCCTAGCGTACAGATCGACGAGAAAATACTGATGCGCTACATAGATCTCAGCAAATCCTCGGCCGTGCCCATGGGCAGCCATTCAGAGGAGGTAGCCCTCCAAGCCCTGCTTGAGGCGAAAGGTAattcggcggcggcggtgttAACCCTTCTGCAGACGCAGTCCAGCGCATTCCAAATGAAATGGACAGCCTACGAACTGGAGCAGTTTTTACGCGGCCTGGAAAGGCATGGCAAAGACTTTGGCAAAATCGCCAGCGAgcTGCTCACCAAGACATCGGGCGAATGCGTgcaaatgtattatttttggaaGAAGCTCTGTGTTGATTACAAGGTATCCCACCTGAAAATGGAGCCAGTTCCGCCCAGTACCCCAGTTGTGGAGCAGAAGCCATACGTCTGCGAGATTGCCGACTGCTCGGCGAGCTTCAGCTCGAAGGCGGCGCTGCACGGTCATGTTCGCATACACGCTTATGGTAGaaatgccagcaacagcaacaacaacaacaacaatcagcatgCCACGGCAATTagtgccaacaacagcaacaaccaccatagttccagcaacagcaacaacaacaccaataacagCAACGCATGCGCGCCCCAGCctagcagcaatagcaatcaATGTATCagtgcaacaataacagcaacaacaaccgtaACGCACACAAAtggcaataacagcagcaacaccaataccaatgccaacaacaataacagcaacaacaacaacatcaacagcaacatcgcCAATGCAACTGGCACTTCCATAAACCCAACGTtgctatcagcagcagcaacaacatcgacagcaacaaaagacaacaacagcaacaattccAATATTGCAAAGGACACCGAGTTCCCCTGCAAGGTGTGCGGCAAGTAA
Protein Sequence: MAAINTVSKSIHLPLTNLSAQRVLMCSASLGSEGSVTLQLRDASTLETADSTTPTTTTTSTSATAATTTTSNPIATSSLSSQSNGVTVLETSSSAASGITSALENALTVGYPDPEMLADVLGTIQTASLKNKHSNNSNNSNNNTSIKRSNNNKSSSTAATILNSSGIHLNSPNKITITRRSASNKISVQTVSTSTNTTISSIGGSKTNYIKNCLIRSSSCSNTATNVTTLAQILSNSSTSSAASLLSQHNNNSNCSNSSNFSIASSVGSIGSVSSNTSNTSSSSNCSSSNSNDSNSSIGQSLSFKSNGRNVAGIVTASTTSTSTAATGIGIVTVDNAPRKSRPKLSSPTRHGPQQCQICSKIFGNASALAKHKLTHSDERKYICALCSKAFKRQDHLNGHMMTHRNKKPYECRADGCGKSYCDARSLRRHSENHHGCVPTSESLSPTASTNGNVSNGTGSVIGSGSSSSSSNGIGVATSSLSLSPATASGDASSPDGATCIRTYISTGSSIVDAATGIALSDEQIRAMNLPIKTGVTLLSPTTSTCSTTSSTASSMSCSSSGNGNGSSIVASSPTITLCDGATLEAEGLTREQLDLISKIMQQTKQTSAQVTVSSPTSVSSYKINTETAQVSARPRTWNMQLLNNVQNVTLTVDEGTELVASASSPPDEVKDDELGQQQLVAAINPHLLNIVKVDKPVECNLCHRKFKNVPALNGHMRLHGGYFKKDPETKRSEKKDSGGPPLQTASIGVRALIEEKIISKRKDINKGAFAVPAPPSSAVNSGVVSCNNNNNSSNSSNNNNNNRNCNLRRSISDLESFLSPKSNANCSLSQALATTCSTTTTTAVLPAATTIKSSSGLSIQQIGLPQSIEIFSGGQRQPKTLSLGSGANTITITTNNVPTTTTMSALSALKGASSISSVSGNADPKDSTLIELLKRGTRIAVTSKKAQNTSTNLLLSNAANAELIGSSIQAATSRQIITNNNRTVIIPSDVHVVSTKSNKMSSNGASNANSISLPDGTPLSLTIGGNQESIGPSSISGGVNGVYAVTYTTNTDAVDLFGNAEVFNVSDTEMLLQTVDTMELMNNEEENEDEGHKQSEHSGNFPLLNSVEDDVLIKLEPESGTPNTNTNTNTNPNQTTTPLPTFQQFHSKELIMQNSSQIQAIANMRGGVLSSPLHSPLAYPTPPSSHENVAQSSPFIEDAAAQFVDANHTFFGDKTDFSHVYFKTDDDCMQQQLSENDNEKILKLKTVLEESAFDASIKVEDLLNGTEDDAECDLREFAETNLSFLDEDQEFLNDSRNATSPLSESFFTSGIGSAEDVKQVLREVLPDENMQLQLSSEQLAENIIDLYYLPGLGLQSQMMSNSDDPLLSSSPRDFGLQRQVVHATTSATSSTVPTMEQLQSSGVMFEQQQQQLQPQQQQVERQELQPQQQQQQLGIGQQPQQQQQSDFMLSNFTPVSCQTQYLDANQQSMTMQPLNNLLQPLLFGSNNSSNNNNNSIDKQQEFGTLLQTTNGQTSALDASLIFACGDGIKSNSNNNKSLIANLPAAAPVATPSPSFSNLQPLSNQTNSILKRRLRSNGAQDVHKFSKFHTLSPHRSKLRKPSRTHYTPAPILNPDRKGTGLYYSVRKQLGQNMFDAFDDDFGDPVGLVDFSDESKVNLGSTYQAQIPACKPLEEAIKETMCADMMWDPSVQIDEKILMRYIDLSKSSAVPMGSHSEEVALQALLEAKGNSAAAVLTLLQTQSSAFQMKWTAYELEQFLRGLERHGKDFGKIASELLTKTSGECVQMYYFWKKLCVDYKVSHLKMEPVPPSTPVVEQKPYVCEIADCSASFSSKAALHGHVRIHAYGRNASNSNNNNNNQHATAISANNSNNHHSSSNSNNNTNNSNACAPQPSSNSNQCISATITATTTVTHTNGNNSSNTNTNANNNNSNNNNINSNIANATGTSINPTLLSAAATTSTATKDNNSNNSNIAKDTEFPCKVCGK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00485798;
90% Identity: iTF_00593355;
80% Identity: iTF_00557142;