Dnen019076.1
Basic Information
- Insect
- Drosophila neonasuta
- Gene Symbol
- -
- Assembly
- GCA_005889595.1
- Location
- MRUE01013994.1:665-3851[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 17 2.6e-06 0.00026 21.6 1.5 2 23 167 189 167 189 0.97 2 17 0.0013 0.13 13.1 3.3 1 23 237 260 237 260 0.96 3 17 0.0019 0.19 12.6 3.2 1 23 326 349 326 349 0.96 4 17 0.0042 0.42 11.5 0.5 2 23 400 421 399 421 0.97 5 17 8.9 8.8e+02 1.1 3.1 1 23 501 527 501 527 0.91 6 17 3.5 3.5e+02 2.3 0.6 1 20 534 553 534 555 0.75 7 17 0.018 1.8 9.6 0.6 1 23 564 586 564 586 0.94 8 17 0.00025 0.025 15.4 2.1 1 23 593 615 593 616 0.95 9 17 0.00031 0.031 15.1 1.4 2 23 624 645 623 645 0.96 10 17 0.0024 0.23 12.3 0.1 3 22 673 692 671 695 0.89 11 17 0.0022 0.22 12.4 1.0 1 23 737 760 737 760 0.96 12 17 1.5 1.5e+02 3.5 3.4 1 22 767 788 767 788 0.96 13 17 0.0062 0.62 11.0 1.6 1 23 797 820 797 820 0.97 14 17 1.4e-05 0.0014 19.3 0.5 1 23 839 862 839 862 0.97 15 17 0.66 66 4.6 0.1 1 23 872 894 872 894 0.91 16 17 0.00031 0.031 15.1 3.2 1 23 900 922 900 922 0.98 17 17 4.6e-05 0.0046 17.7 0.9 1 23 928 950 928 950 0.98
Sequence Information
- Coding Sequence
- aTGACGAGAACATGCCGAATATGCGGCGGGGCAGATGGACGCTATTGGATTGAGACGCCAGTGAATAAGTACGCTGAAAAAACATTCAATCAACTGTTATTGGAATTAACAAGACTTGAGGTCGCCTTGAATCATGTTGACAAGCTTCCGCCCTGGCTGTGTCGTGTTTGTGCAAAAAACCTGGAAAATGCCTATGATTTCGTACTACAAGCACGCGAATCCCACGAACTGTGGATAAAGAAGCTGTCAACCGATGACACGGAGAAGGGAACTTTTGAATGTCTGCGTGAGACTCCAATACAATTGCTGGACATTGAAGGCGtgataattaaaatggaaGAACCCGCCGACCCTGCAAACACACCTCAATCAGATCCCAACATTTCTGTTGACCCGCTAATTAAGAAGAGTATTGTGGACGATGAAAgcgaagatgatgatgacgatgtgcCATTGAAACAGCGTAAAGTGAATCAAGCTAAGTTGCCCATAAACCGCAAATGCAATATATGCGGAAAAGCCTTTAAGTACGCGACAAATCTCTTTAAACATAAACAGCGGGACCACGCGAGTGATTATCAGGACAAGTTAATAACGAAATCAAAGGGAGAAAATCATTCACAGCAATTCCTACACAATGTATCAAAAAGACCTGCGGTATCTCGAAGTAGTGCCAATTCAGACTTTGACAATGACGATGATAACTACTACAAATGTGATCAATGCGATAAATCCTACAAGTACATTATGCTGCTCATTAAGCACAAACACAAGGTACATGGCGTCAACCAGTTACCAGCGGTACCTATGCCAATTTCAGGACCCAAATCCAGTTCTGAAGAATCAACCAAAACAAGACCCACACAACGAAAGCGTTTGAAGCCTCCGAGCACTGATTCCTTGGTGCACAGCTTAATCAAGGAGGTTAAAACACCTGAAGAGGAGGACTTAGAAGGCACCAGCTCAgataattattacaaatgcGATCAATGCGAGAAATCCTATAAATACATTGTGAGTCTCAtcaaacacaagcacaaggAGCATAGTGAATACAAAGattctgatgatgatgaggacgaAGCATCACTATCCAAATATCCAACGGCAGCTGCCAATTCAAAACCCACACGCATCGATCGTCGGGTGAAAGGCTTCGATTTGCATCGCTGTAAACCAAATGGAATCAAGGAGATTCAGTGCATGATCTGTTTGAGAAGATTTGGTAAACTGAGAGAGCTTCGCAATCACCTTAGAGCACATCCCAATGACATTACATTCGAGGCTCACGGAGAGCCCATTGAACGCATTGCTGAGGGCTTCTATCGCACAGCTGTGGAGTCAACTGCGGATGGTTTGAAGACACGTATTCTTAATGATCTCAAGGTTGGCATGTACGGCCGATACTATTCCATCACCAATGAGGCGCGTTATGAGATGAATCTGGACAGCTCAGACACTGACAGCGATGGCGAATGTGGAGTTGTTGAGCGACGTAGTTACGCCTGCGAACTGTGCGATTCACATGCCGCCATTTACCCGCGCAAATTTCAGCTACATGAACATCATCGACAGCAACACACTTGGCTAGAGGCGCCATACATTTGTTCACGTTGTGATTCGCGTTTCCTCAGCGCCCAATTGCTCGATCATCATACGAATAAATTATGCCAGAATACCCTCAAGCGTTTCATGTGCGACAAGTGTCCACAACGCTTCTTCTGGCGTCGCAATTTGCGTGCTCATCTCGTCGAGCACAAAAACAAGCAAGAAATTTACCCCTGTGATCAGTGTTCACGCAGTTTTCAGGATAAAAGCGCGGTGACAAAGCATAAGCTGATGCATCACGATGGCAGCCACGAACTGATTCCTTGTCGTTGGTGCACTCGCACTTTTTATCGTCCAGCTTTGCTGCATAAACATGTTAAACGACATGGCTTCACCGGAGAGGATTTGCCCTTGGCGGAGACATTGCTGGCCTATGCCGCAAAGTCATCCGGACCTAAGTCGATCATTTGCAAACTTTGTGATATGCAGTTCATTAGCATAGCTGATTTGCGGCGACACATTTCCATGCAGGGTCACAGTGAAGACCCATCCAACTATATGATTAGCACAGAGGAAGGATTTGAGTTGCATCTGGATGAGACGGACGACAGCGATGATGAGACTACAACTACTAACGCCGCCCCTTCTGCTGGCAGAACCTACAAGTGTGATCTTTGCGATGCGACGTTCCAGCGGCGTCGTGACATGAGCGAACATCAGTATTCCTTGCATACCTTCGATAAACTACCACATTCCTGTGAACATTGTATTTACAAGACGGTCGACAAGTACATGATGCAACATCATTTGCGGACGCAGTGCCTCAACGAGCAgaagaaattcaaatgttCCCGCTGTGGCTTTAAATTCATGTGGAAGGAAAATCTGGATCAGCATATGAACAGCCAGCATACTCATGTGTCAAGTCAGGCCCCAGTTCAAAACAAGCGAAGTCGCCGCTTCAGATACCAGTGTCCGCATTGCTGGCGATCTTTTGTTGTACAACCGAGCCTGGATAAACACATACGCGACATGCACGTAGCCAAAAAAAATCCTGGCAAGAAGTATCTCTGCTCATTGTGCGGCCTGGAGGCGCTTACGCCCAACAAACTGGCAATCCACATGCAACGCCACAATGGCGAAAAACCACACAAATGCGATCTGTGCGAGATGTCCTTTACAGTCTTCTACGAGCTAAAAGTTCATCGTCGAAAGCATACGGGCGAGCGTCCCTATCAATGTACATTTTGTGCCAAGGATTTCGCACGCCCCGATAAGCTTAGACGACATGTTTACATGCACAGTGTAAGGCGTTAG
- Protein Sequence
- MTRTCRICGGADGRYWIETPVNKYAEKTFNQLLLELTRLEVALNHVDKLPPWLCRVCAKNLENAYDFVLQARESHELWIKKLSTDDTEKGTFECLRETPIQLLDIEGVIIKMEEPADPANTPQSDPNISVDPLIKKSIVDDESEDDDDDVPLKQRKVNQAKLPINRKCNICGKAFKYATNLFKHKQRDHASDYQDKLITKSKGENHSQQFLHNVSKRPAVSRSSANSDFDNDDDNYYKCDQCDKSYKYIMLLIKHKHKVHGVNQLPAVPMPISGPKSSSEESTKTRPTQRKRLKPPSTDSLVHSLIKEVKTPEEEDLEGTSSDNYYKCDQCEKSYKYIVSLIKHKHKEHSEYKDSDDDEDEASLSKYPTAAANSKPTRIDRRVKGFDLHRCKPNGIKEIQCMICLRRFGKLRELRNHLRAHPNDITFEAHGEPIERIAEGFYRTAVESTADGLKTRILNDLKVGMYGRYYSITNEARYEMNLDSSDTDSDGECGVVERRSYACELCDSHAAIYPRKFQLHEHHRQQHTWLEAPYICSRCDSRFLSAQLLDHHTNKLCQNTLKRFMCDKCPQRFFWRRNLRAHLVEHKNKQEIYPCDQCSRSFQDKSAVTKHKLMHHDGSHELIPCRWCTRTFYRPALLHKHVKRHGFTGEDLPLAETLLAYAAKSSGPKSIICKLCDMQFISIADLRRHISMQGHSEDPSNYMISTEEGFELHLDETDDSDDETTTTNAAPSAGRTYKCDLCDATFQRRRDMSEHQYSLHTFDKLPHSCEHCIYKTVDKYMMQHHLRTQCLNEQKKFKCSRCGFKFMWKENLDQHMNSQHTHVSSQAPVQNKRSRRFRYQCPHCWRSFVVQPSLDKHIRDMHVAKKNPGKKYLCSLCGLEALTPNKLAIHMQRHNGEKPHKCDLCEMSFTVFYELKVHRRKHTGERPYQCTFCAKDFARPDKLRRHVYMHSVRR
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00579434;
- 90% Identity
- iTF_00562613;
- 80% Identity
- iTF_00553855;