Dneo016938.1
Basic Information
- Insect
- Drosophila neocordata
- Gene Symbol
- -
- Assembly
- GCA_018903615.1
- Location
- JAEIGI010000002.1:17547610-17550618[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 13 1.7 1.4e+02 3.3 2.6 3 17 61 75 60 76 0.92 2 13 0.0022 0.18 12.4 0.0 1 23 198 221 198 221 0.96 3 13 5.9e-05 0.0048 17.4 3.7 1 23 226 249 226 249 0.96 4 13 4.8e-05 0.0039 17.7 2.9 1 23 254 276 254 276 0.98 5 13 0.00021 0.017 15.6 5.6 2 23 283 304 282 304 0.97 6 13 0.00074 0.061 13.9 3.0 3 23 317 338 316 338 0.95 7 13 0.0022 0.18 12.4 0.2 1 23 344 367 344 367 0.96 8 13 0.0085 0.69 10.6 0.7 2 23 378 400 377 400 0.95 9 13 0.0008 0.065 13.8 0.4 1 23 428 450 428 450 0.95 10 13 0.001 0.082 13.5 4.9 3 23 459 479 457 479 0.92 11 13 8.1e-05 0.0067 16.9 0.2 2 23 486 507 486 507 0.97 12 13 0.00045 0.037 14.6 0.8 1 23 514 536 514 536 0.99 13 13 0.00013 0.011 16.3 2.4 1 23 542 565 542 565 0.98
Sequence Information
- Coding Sequence
- ATGGAAACGTGTCGCACCTGTGCACTTTCCATGTTTGTCTGTGATTTTGAAAATGGCAACAATAATTTCTTGGACTTATTCCATCCCACATGCTGGCAGAGTGAAATGGCTCAAATACGCTTGGAGTTTGTTAACTGGAATTTAAAAATACTGCCTAATGATGGCCTGCCACAGAAGATCTGCAGCGATTGTTTTACTAAATTCTGTTCTCTTTATAATTTTCGATTGGCATGCCAGGAGGCGCAAGTAAAACTATTGAATATTTATGAAAAAATTGATGCCAGCAGTTTAGATGATGACACGGAAGTTGAGGAAGGCGTAGTAGAGCTAGAATATAATGATAATGTCAAAAGAGCACCAAAAACAATGACGGTTTCAATTGAAACATCAAACACTGCCACCGTTTCTGCTCCAACTACAGACCCTATAGAAATCTATATAGATGCGGCAAATGTTGCAGATACAACCAAAAATTCTCCAGAACTGGCAATAAGCTATGCGTGTAAATTTTGTTTTAAGCCACAGGAGAGTTATCAATTGCAGCAATTGCTCCTCGAACACATCAGTACCGCACACGACCCGGAGCAACCGTATAATTGTCCTGAATGCAAAGCTGCTTTTCAAGATGCGGCTTCCCGTACAGTCCATATGAAGGGTGTCCATGTGGAAAAACAATTTTCTTGTGATGTATGCGGCAAAAAGTATGGAGATCGTCACAATCTTCGTCATCATGTCGAGAAATATCATTCCGACACAGATTTCGAATGCAGCATGTGTGAGAAACGCTTCTTTACAAGAAAAAGTCTAAAATATCACATTAAATGGCATAACCCAGACCGCCAGTTAAAATGTCCTCACTGCGAAAGATTGTTCATCAATCACAGGCATCTTACTACACACATGGCCACCCACAATCATATGACAGCCAATGCCCGGAAGAGCGAGCATTGTGGTTTTTGTGGCAAAGCCTTTATACACCTTAAAACTCTACGTTGGCACATTTATAAACAGCATGGCGGGGAGAAGCCCTACAAATGTGGAAACTGCACGGAAGTTTTTGCTTCATATGCCGAAAAACGGATACACATGCTGGAGACGCATATGGAGAATCTGACGGCCATTGAAAGAAGTGAATGCATGCTGTGTAGACAGGTATTTGGGAACGAACAGGACTTGGTTCACCATATGACTAGGGAGCATTTAAAAGGTCCTTCGGCCCCGGTTATAGTCAATAATAAACGTGTTTTGCAACAAAAGAAAGAACGTCAGTATTCGGGGCTTTTTCAGTGCCAAAGCTGCCCTCAACGTTTCAATATGAAGACCGCACTAGAAAGGCACGAGGTTGTCCACAGCGAAAAGGACCGACCACATGCCTGTATCCATTGTTCTAAAAGATTTAAGCGTGCCCAGGACATGAAATGGCACATGAAAACGCATGAAAAAGAGAAACCTAATGTGTGTGATGTATGTGGCAAGGCCTTTGCCCTAAAATATGTGCTCACCCAACACAAACGGAGTCATGAAGTTCTCGAAAAGAACTTTAAGTGTAATGTATGTGGACGTGCATATCTCTTTGAAAAATCGTTGCGTTTGCATCAACGAGTGCATACAGGCATGACCTTCTACAGTTGTGACCTCTGTCAGGAGCGTTTTGTCACCCACATCAAATTAAAAACTCATATGCAAAAGATCCACGCCCAGATGCAAGCAAAGGATTCCTCATTGGATGAATTGATTAACATTGTGATTTCCTAA
- Protein Sequence
- METCRTCALSMFVCDFENGNNNFLDLFHPTCWQSEMAQIRLEFVNWNLKILPNDGLPQKICSDCFTKFCSLYNFRLACQEAQVKLLNIYEKIDASSLDDDTEVEEGVVELEYNDNVKRAPKTMTVSIETSNTATVSAPTTDPIEIYIDAANVADTTKNSPELAISYACKFCFKPQESYQLQQLLLEHISTAHDPEQPYNCPECKAAFQDAASRTVHMKGVHVEKQFSCDVCGKKYGDRHNLRHHVEKYHSDTDFECSMCEKRFFTRKSLKYHIKWHNPDRQLKCPHCERLFINHRHLTTHMATHNHMTANARKSEHCGFCGKAFIHLKTLRWHIYKQHGGEKPYKCGNCTEVFASYAEKRIHMLETHMENLTAIERSECMLCRQVFGNEQDLVHHMTREHLKGPSAPVIVNNKRVLQQKKERQYSGLFQCQSCPQRFNMKTALERHEVVHSEKDRPHACIHCSKRFKRAQDMKWHMKTHEKEKPNVCDVCGKAFALKYVLTQHKRSHEVLEKNFKCNVCGRAYLFEKSLRLHQRVHTGMTFYSCDLCQERFVTHIKLKTHMQKIHAQMQAKDSSLDELINIVIS
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00555257;
- 90% Identity
- iTF_00483874; iTF_00591127; iTF_00577946; iTF_00600483; iTF_00501232;
- 80% Identity
- -