Dnav003888.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila navojoa
Gene Symbol
Ankfy1
Assembly
GCA_001654015.2
Location
NW:46610-55204[-]

Transcription Factor Domain

TF Family
BTB
Domain
zf-C2H2|ZBTB
PFAM
PF00651
TF Group
Zinc-Coordinating Group
Description
The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 1 7.1e-10 1.5e-07 31.1 0.0 9 108 72 167 66 169 0.89

Sequence Information

Coding Sequence
ATGGGTTGCAATGATGTCGATTCAATTTCAAAACTGGAAAAGGACCTTGCTCTTTTAAAGGAAGAATATAACAAACTTCAGCGCAGCTATGTGGAATTGGAGCGGAAATATAATGAAGCTATTGTGTCGACTTCAGATCTGGAGTCTTCAGGAGAATTTAGCAGTTTTGTATCAAGATTGGCACTGACGACGGCCTCTTTATATGGACGCTCCATATATTCCGATCTGAACATTAAGACCAATTCCAATGGGACAATAATGCCGGCCCACAAATTCGTACTCCATGCCCGGTCGGACAAATGGCGTAACGAGGCATTAGCCACTGCCAAAGAATTAGATTGGAGCGATTTGGATGAGGATATAGCCACAGCGTTGCTACGCTGGATTTATACAGATATTATTGACTTGCAGCATGATCGATTGACCTTGGGTCTGCTGAGAGTGGCGCACCGTTTTTCCTTACCTGGACTGCTCGGGCTCTGTGAGAGAGCTCTGGTGGCTTCTGTGGGCGTACGATCTTGTGTGCGATTCTATTGTGTGGCCGAAGAAGTGGGCGCAGCTAGCCTACTTGAGTATTGCTCCGGCATTATATCGACGCACTGGGATGATCTAACTGCACAGGATTTCGAACACATGTCTGGACCGCTTCTCTACAAAAtgctcaaaaacaaaaccaaatatcCTCTACACTCAGCCGTCCGACTTTTGCGCGAAGATGTTGTTTGCTTGTGCCTTGCGGAGAACAGTAATTCGTTGCCCGAACTGGTGAATAGTTTGTCTGAGCATGGACAGCTACCACTGCAGATGGCATTGTCGGCGAAAAGTGTTCAAATTGCCCAGACTCTGGTTAATAATGGATCtgcgaatgtgaatgcctATGATGCCAAGGGATCTACGCTTCTTATAGATGCTGTAAAAAAAGCCGATAGTTTTGCAGCAGACTTTCTATTAAATCACAACTGCCTTGTTGATCTTGTGTCCAGgTCGTCATCCGATACAGCACTCCACATTGTATGCAGCTATGGCGAAACTAACGAAAATCATGAAAATGTATCCCACATGATTGATATCGGCAAGAAAATATTACAGCGCAAGGCTAATGTAAACCTTCAAAATAGCCAAGGACAAACGCCGCTGCATATTGCAATCATATCTCAAAATAAGGCTATGGTGGAGCTATTACTTGATGTGCCCGATATTGACATTAACTTGCGTAGCAATGATGAGAAATGTCCTCTTGAATTGACGTTGGTTCCATTCAATAAGGAGCTTGCTGCTAAACTCCTCAAGATGGGAGCCAACCCGAATCCATTGAAATCTGGGACAAATAACAACCTGCTGCAAGTGCTTGCCATGGGTGGGAGAGAATTTGAAGAGGCTGCTATATTTTTGACTGACTTTGCTGACCTTGAGCACCTTAACAACGCTGGCTTTTCTGCCATCCACATCGCTGTCCAAAAGAACATGCCGAAATTTGTGGCGAAACTTCTTGATGCTGGCGCTGCTCCCAATATACAAACGACTTCCGGCAATATGAAGTCACCCCTACACATAGCTGTGGAACAAAATGCTCAAGAGATTCTTGAGACATTTGTTAACTTCAGCAAAAGCCACTCTGAAAAAGTCGATTTCAACTGCAAAGATGAAAGTGGCAATACGCCTTTAAGCTTATGCTTAGCCCTTAATCGCATTGAATTAGCTCCAATACTTATCGCTGGCGGCGCTGATGTGAATGCGCGCAATGGACAGGACTTGACTTTGTTGCATCAATCTATAATCAGCGGCGACAGCGAGAAGGCAGTTTTCCTACTGGACCAAGGCGCCGAAATTAATGCGCTTACAGGTGATCAAAAGTCTGTCCTTCAACTGGCTATCGATTCCCATCTGCCCAAGGTTGTTGACGTGTTATGCATTAAGGGCGTGGACCTTAGCACCTTGGACAGTTCAAGAGATTCACCTTTATGGACTGCTCTAGAATTGGGATTTGAGGATGTTGCGCAAATTCTAGTTCGCCATGGCGTTGACACCGATTGCTGGAGCCAAGGACCTGAGGGCTGCCAGCAGACACTGTTGCACCGGGCCATCGATGAAAACAAGGAGGCCACAGCAATTTTTCTCGTTCGCAATCAATGCGACTTGGACTCTCCGCGCCAACCGGGTCCAAATGATGAGGGTGGTGACGAAGCTCGCGACAAAGCCTCTCCTTTGCATCTCTGCTGTCAATGGGGTCTGACAAAGGTTGTGCAGGCACTTATTGATCACGGCGCCAATGTGAACGCTGTAGACGCTGAAAGCAAGACTCCAGCACACATAGCTATAGAAAACCAGCATgaagatattataaatatccTGTTGTGCCATCCCGGAATAGACCTGAAGTTGCGGGATAAATCCGGTCTGACGCCTTTTGCCACTGCTCTGGCCATCCGCAATCACAAAGCCGCTCAGCGCATACTTGAGAGGCTGCCAAATGCAGCCGAAATAATGGATAATCGTGGACGCAATTTCCTGCACATAGCTATATTAAAAGATGACCTCGAAAGCGTTCTCTTTTTGTTGGCTATTCAAGTAGACGTCAATTCCCGCGTCCACGACGCCTATCAGTCCACTCCACTTCATCTAGCAGCTGCGTCGAAAAACGAAATGATTATACGGAATTTAATACTGGCCGGCGCTCGCATCAACGAACGTGATGCTGTCCAGAAAATGCCGCTTCATATAGCAATCGAGCGCGGAAATCTTGCGGCAGTTTCGGCGATGATCCAAAATAATGCCGACTTCGATGCAACCGATGCTGATGGAAACAATGCCTTGCACCTTGCGGTCCACGGGGGTCAGCTGGCGATAGTCCGCGAGCTGCTGACCGAATCGCGAGTAAATGCGGAGGCAACCAATGCGAGGGGCCGCAATCCCTTGCATGAGCTGTGTCGCGTTGGCGAAGACAATTCCGGTGCTGCCATATGTGAACTGTTTCTTGAGTGCATGCCGAAGTATCCGATTAACGTGCCCGACATGGACGGCAACACACCACTGCTGCTCTCGTATATGCGAGGACAAGCTCCACTTTGTAAGGTTCTTGTAAAAGCGGGCGCGTGTCTTGGGGCTCAGAACCGAGAGGGaatcaatattttcaattacaaacTAGCGACAGATCAATTGCTGACTAAATTGTTGGACCAACTGCCTCAGGAGTCGCCGTGGGCAGAGTCTGAGCTGTGCCAAGAGTGTGGCTTAAAGTTTTCACTGACCATAAGAAGGCACCATTGTCGACACTGTGGAAGAGTTTTGTGCTCCAAGTGCTCCAACAACGATGTACCGATTGTCAAGTTTGGCATTAACAAACCCGTAAGAGTCTGCAAGGTGTGCTTCGATGTACTTCATGGAGGCAGCTAA
Protein Sequence
MGCNDVDSISKLEKDLALLKEEYNKLQRSYVELERKYNEAIVSTSDLESSGEFSSFVSRLALTTASLYGRSIYSDLNIKTNSNGTIMPAHKFVLHARSDKWRNEALATAKELDWSDLDEDIATALLRWIYTDIIDLQHDRLTLGLLRVAHRFSLPGLLGLCERALVASVGVRSCVRFYCVAEEVGAASLLEYCSGIISTHWDDLTAQDFEHMSGPLLYKMLKNKTKYPLHSAVRLLREDVVCLCLAENSNSLPELVNSLSEHGQLPLQMALSAKSVQIAQTLVNNGSANVNAYDAKGSTLLIDAVKKADSFAADFLLNHNCLVDLVSRSSSDTALHIVCSYGETNENHENVSHMIDIGKKILQRKANVNLQNSQGQTPLHIAIISQNKAMVELLLDVPDIDINLRSNDEKCPLELTLVPFNKELAAKLLKMGANPNPLKSGTNNNLLQVLAMGGREFEEAAIFLTDFADLEHLNNAGFSAIHIAVQKNMPKFVAKLLDAGAAPNIQTTSGNMKSPLHIAVEQNAQEILETFVNFSKSHSEKVDFNCKDESGNTPLSLCLALNRIELAPILIAGGADVNARNGQDLTLLHQSIISGDSEKAVFLLDQGAEINALTGDQKSVLQLAIDSHLPKVVDVLCIKGVDLSTLDSSRDSPLWTALELGFEDVAQILVRHGVDTDCWSQGPEGCQQTLLHRAIDENKEATAIFLVRNQCDLDSPRQPGPNDEGGDEARDKASPLHLCCQWGLTKVVQALIDHGANVNAVDAESKTPAHIAIENQHEDIINILLCHPGIDLKLRDKSGLTPFATALAIRNHKAAQRILERLPNAAEIMDNRGRNFLHIAILKDDLESVLFLLAIQVDVNSRVHDAYQSTPLHLAAASKNEMIIRNLILAGARINERDAVQKMPLHIAIERGNLAAVSAMIQNNADFDATDADGNNALHLAVHGGQLAIVRELLTESRVNAEATNARGRNPLHELCRVGEDNSGAAICELFLECMPKYPINVPDMDGNTPLLLSYMRGQAPLCKVLVKAGACLGAQNREGINIFNYKLATDQLLTKLLDQLPQESPWAESELCQECGLKFSLTIRRHHCRHCGRVLCSKCSNNDVPIVKFGINKPVRVCKVCFDVLHGGS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01328007;
90% Identity
iTF_00493771; iTF_00544609; iTF_00540487; iTF_00532492; iTF_00545359; iTF_00551700; iTF_00599703; iTF_00549662; iTF_00476740; iTF_00586792; iTF_00546766; iTF_00502642; iTF_00520030;
80% Identity
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