Basic Information

Insect: Drosophila nasuta
Gene Symbol: ush
Assembly: GCA_017165715.1
Location: Scf:323-17017[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.0055 0.35 11.0 0.0 1 20 189 208 189 210 0.90

2 9 0.00024 0.015 15.3 0.8 1 23 265 287 265 287 0.98

3 9 0.042 2.7 8.3 1.0 2 21 338 357 338 358 0.92

4 9 0.041 2.6 8.3 2.9 2 21 741 760 740 761 0.93

5 9 0.0076 0.48 10.6 0.0 3 21 813 831 811 832 0.91

6 9 0.016 0.99 9.6 0.0 2 23 895 916 894 916 0.98

7 9 0.0032 0.2 11.8 1.3 1 23 922 944 922 944 0.99

8 9 0.00055 0.035 14.2 0.7 1 23 1012 1035 1012 1035 0.96

9 9 0.34 22 5.4 0.5 2 20 1147 1165 1146 1167 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.0055	0.35	11.0	0.0	1	20	189	208	189	210	0.90
2	9	0.00024	0.015	15.3	0.8	1	23	265	287	265	287	0.98
3	9	0.042	2.7	8.3	1.0	2	21	338	357	338	358	0.92
4	9	0.041	2.6	8.3	2.9	2	21	741	760	740	761	0.93
5	9	0.0076	0.48	10.6	0.0	3	21	813	831	811	832	0.91
6	9	0.016	0.99	9.6	0.0	2	23	895	916	894	916	0.98
7	9	0.0032	0.2	11.8	1.3	1	23	922	944	922	944	0.99
8	9	0.00055	0.035	14.2	0.7	1	23	1012	1035	1012	1035	0.96
9	9	0.34	22	5.4	0.5	2	20	1147	1165	1146	1167	0.91

Sequence Information

Coding Sequence: ATGACCGTCGACAGCAGAGATTCCAAAGATTTAGGTTCACACGAACTGAGCGAGGAGAAGGAGCAGCAGCACGACTTCGAGGAGCTGCCAGAAGAGGAGGAGGACGAACATCCTAGCGAGGAGAACCAAACAAGCAACCACAGCTCCGACCAGCCCATGGAGACTGACATGGACCAAGTTGAGGCAGAAGATGCCGATCACGAGGAGCAGCAACAGCAGCAGAAGGAGGCTGACAACTCGACGACACCGCCGCGCAGTCCGACGCCGCAGCTGGTGCCAAAGCTGGAGCGGATGGAGCAGCCAGCCACACCGCCATCAGCAGCAGCCACGCCCAGTCCCCCGCCCACACCCACACCTATAACTGCTGCGCTACCGAAGCTGCGGCTTAATGCATTGTTAGCGTCGGATCCAGCGCTCAAACCCGACGCCAAGGAGCTCAATCTGGCCGATGCTCGGCTGCTCGCTCCGCCACCGCAGCTGTCCAAGCCGGAACCGTCATCTTCTCAGAGTCTAGCCGAGGCAGCCAGCAGCAATCTCGTTGAGCCGCTGCTGAAGCCGGCGCGCTTCATGTGCTTGCCCTGTGGAATTGCCTTCAGTTCTCCATCGACCCTGGAGGCGCATCAGGCTTACTACTGCTCACATCGCAACAAGGAGGCGGACGAGGAGGCCGGATCGGGCGATAAGCTGTCAGCTGCGGGAGGCGGAGGCGCCGCTGGCACCGGGAACAGCAACAACAATGGCGGAGGAAGCAGCTCGGAGCCACCGGCGAAGGTGGCGCGCACAGGAAAGCAATATGCGTGCACTCAGTGCTCCTACAGTGCCGACAAGAAGGTCTCCCTCAACAGGCACATGCGCATGCATCAGACCTCGCCAGCTCCCAGCCTGCCCAGCCTCGCCGGCCTGACTGCCAATGGCGTGGCAGCTGTCGGAGGAGTCGGAGTGGGAGTTGGAGGTGCTAGCGGAGTCGCGGCGGGTTCGCTCGAGGAGAGCTCTAGTCAACAAATCGATCGCTATTGCAGCGACTGTGATATCCGCTTCAACAACATCAAGACCTATCGCGCACACAAGCAGCACTACTGCAGCTCCCGCCGCAACGACGGCCAGCTCACACCCAAGCCCGAGGCGGGCGTCGGTTCAGGCTCATCCGGCACTCCCGGCACAGCCACCCCGGTCGGTGCTGGCAAACTGAGTGGAGCGCACAGTCCACAGTCGCGGAACAAGACCCCGACTCCCGCCATGGTGGCTGCTGCCGCCGCCGCTGCAGCTGCTGCTGCCTCGTTGCAGGTGACGCCGCCACAGCCCTTCCTGGCACTGCCCACCAACCCGATCATAATTGTGCCCTGCTCGCTTATCCGCGCAGCCAGCCTCATTCCGGGACCGCTGACCACCTCGACTTCGGGCATCGTCAACCCGGAGTCCACTTGCTTCACCCTCGACAACGGCGCCTTGAAGCCGCTGGCCACAGCACTCAACATCAATGCGTTGGCCGGAAATGTGACTCCGACGCCGCCAATGCCCAGCAGCAATCAGCAACCGATTCCTGCCCTGGAACCAGAGCGTCAGTCAGCAAGCAACAGCGAAGCTGAGACCAAGAGCAGTCCCACTGAGCCCAAGCGCAAGGAAGCGGGAGGAGGCGTCACTCGCGAGTCTACCCCACTGGATCTCTCCCTGCGTCGTTCTCCTATCTCGGCGCTGTTGCAGCGTCAGCGTCTCGTGCGCTCCGCTGCCGCATTGCTCGAGGCAGAGGAGGCGCTCTTGGCTGCTGCAGGCAAAGAGAACCTGGAGAGCGGTGGTAGCGTTACCCCCGAGCAGATTGTGTGCGCTCCCTCGCTGCCCAGCAGTCCCTCGATGAGTCCCTCGCCCAAACGACGGGTCGTGAGTCCTCGCAGCTCCGGCGCTGGCAGCGCTGCCTCCATGTCGCCGCCCACTTTGGGCGTAGGTGTAGGTGTGCCACATCTGCTGGAGAATTTGCCACCGCTGCGCTCCATGCTGCCTGCGGACTTTGCGCTCTCCGAGTCCCTGCTGGCCAAGACCAACCCTGAGTTGGCGCTCAAGCTGGCTGCCGCTGCCGCAGCGGCTGTGGCAGGCAGCAGCACTGCGGAGCTGGCCAGCAAACTGGGCTTCCCCACTGCACCTGGAGCCGGAAGCAACGCTCCAGCTGCGGCGACAGCCAATGCGCCAAGTGCACAGCCACAGATCTATGTGAAGCAGGGCGTGTCCAAGTGCAAAGAGTGCAATATTGTCTTCTGCAAGTACGAGAACTATTTGGCCCACAAGCAGCACTATTGCTCCGCCCGCAACCAGGAGTCGGGCGAGGGCGATGCCAAGAGCGCCAGCTCGCCGCCAAGCGGAGCAGCGACAGCGCAAGTTGGAGCTGGAGTGGGAGGAGCTGCCTCCGCGGCAGAGACTACGCCGGTGGCGTATCAGCAGCTGATCTGCGCTGCTTGTGGCATTAAGTACACATCGCTGGACAATCTGCGTGCGCATCAGAATTACTATTGCCCCAAGGGTGGCGCAGCAGCCACGCCAGTTGCTGATCCCCCACAGCTGCCCAAGGAAAAGTGCGGCAAGTGCAAGACACTTCACGAACTTGGCCAACCTTGTCCACCTCCGGCTGCTCCCCAGCTGCCTCCACTTGCGGCAACCGCGGCCGCGTCGGGCGCCTCCTCGAACAGTGTCAACAAGTGTCCCGTCTGCGGTGTTATTAGTCCTACAGCAGCGTTGGCCAGGAAGCACATGGAGATGCATGGCACAGTGAAGGCGTTCCGCTGCAGCATTTGCCAGTACAAGGGCAACACGTTGCGTGGCATGCGCACTCACATTCGCACCCATTTCGACAAGAAGACAAGCGACGTGAACGAGGAGCACTACATGACTTGCATCTTCGAGGAGGATGCAGCTGCCGCGGCTGCTGCTGCTGCGGCTGCAGCTGTTGCTGCGACTCCCGTTGGACTCGGTTTGGATGTGCCGGTTGTGGCCTCGCCTCAGGAGCAACTGGAGCAGCAGCAGCACGCGCAACATCCGCCACAGATCTTCAATTGCGACTACTGCAACTATGCGTCTAGCTACAAAGGCAACGTGCTGCGCCACATGAAGTTGCTGCATCCACACGTGGCCATCAACTCGCCCTCGATTTCGCCAGAGACGCGGGACCAAGAAATCAATCCGCATGCCGAAGTGGCGCTCGTCAATGGCGATCGCGATTGCTCATCAGTAGCCAGTTTCCACATTAAATCGGAGCCTCTAGAGCAACCACCCGTGGCAGCAACGCTGAGCTTGGTGCATGACAACAACAACTCACCCATTGGCACACCACACACTCACATCAAGGCCGAACCTCAGGACATAGGCATGGATGTATCGCCTCCTTCGCTGCCGCCGCCGCCAGTGTCGAACTCTCCGCTGGGAAACAGCGCAGCGGCCGAGGCCATGAAGAAGTACTGCTCCACCTGCGACATATCCTTCAACTATGTCAAGACCTATCTGGCCCACAAGCAGTTCTACTGCAAGAGCAAGATGCATCGTCCCGAGGCCAACGATAGCCCCAGTCCCAATCACATGAATCACAATCACCTGGGTGCCACTGTACCGCTGCAGTCGCCCAGCGAGCTGCTGCTGCTCCAGAAGAACAAGGAGAATCTACAGGAGGCGGCCATTTGA
Protein Sequence: MTVDSRDSKDLGSHELSEEKEQQHDFEELPEEEEDEHPSEENQTSNHSSDQPMETDMDQVEAEDADHEEQQQQQKEADNSTTPPRSPTPQLVPKLERMEQPATPPSAAATPSPPPTPTPITAALPKLRLNALLASDPALKPDAKELNLADARLLAPPPQLSKPEPSSSQSLAEAASSNLVEPLLKPARFMCLPCGIAFSSPSTLEAHQAYYCSHRNKEADEEAGSGDKLSAAGGGGAAGTGNSNNNGGGSSSEPPAKVARTGKQYACTQCSYSADKKVSLNRHMRMHQTSPAPSLPSLAGLTANGVAAVGGVGVGVGGASGVAAGSLEESSSQQIDRYCSDCDIRFNNIKTYRAHKQHYCSSRRNDGQLTPKPEAGVGSGSSGTPGTATPVGAGKLSGAHSPQSRNKTPTPAMVAAAAAAAAAAASLQVTPPQPFLALPTNPIIIVPCSLIRAASLIPGPLTTSTSGIVNPESTCFTLDNGALKPLATALNINALAGNVTPTPPMPSSNQQPIPALEPERQSASNSEAETKSSPTEPKRKEAGGGVTRESTPLDLSLRRSPISALLQRQRLVRSAAALLEAEEALLAAAGKENLESGGSVTPEQIVCAPSLPSSPSMSPSPKRRVVSPRSSGAGSAASMSPPTLGVGVGVPHLLENLPPLRSMLPADFALSESLLAKTNPELALKLAAAAAAAVAGSSTAELASKLGFPTAPGAGSNAPAAATANAPSAQPQIYVKQGVSKCKECNIVFCKYENYLAHKQHYCSARNQESGEGDAKSASSPPSGAATAQVGAGVGGAASAAETTPVAYQQLICAACGIKYTSLDNLRAHQNYYCPKGGAAATPVADPPQLPKEKCGKCKTLHELGQPCPPPAAPQLPPLAATAAASGASSNSVNKCPVCGVISPTAALARKHMEMHGTVKAFRCSICQYKGNTLRGMRTHIRTHFDKKTSDVNEEHYMTCIFEEDAAAAAAAAAAAAVAATPVGLGLDVPVVASPQEQLEQQQHAQHPPQIFNCDYCNYASSYKGNVLRHMKLLHPHVAINSPSISPETRDQEINPHAEVALVNGDRDCSSVASFHIKSEPLEQPPVAATLSLVHDNNNSPIGTPHTHIKAEPQDIGMDVSPPSLPPPPVSNSPLGNSAAAEAMKKYCSTCDISFNYVKTYLAHKQFYCKSKMHRPEANDSPSPNHMNHNHLGATVPLQSPSELLLLQKNKENLQEAAI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00509368;
90% Identity: iTF_00472623; iTF_00562736;
80% Identity: -