Basic Information

Insect: Drosophila albomicans
Gene Symbol: ush
Assembly: GCA_009650485.1
Location: NC:29929311-29990821[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.0058 0.35 11.0 0.0 1 20 212 231 212 233 0.90

2 9 0.00025 0.015 15.3 0.8 1 23 288 310 288 310 0.98

3 9 0.045 2.7 8.2 1.0 2 21 361 380 361 381 0.92

4 9 0.043 2.6 8.3 2.9 2 21 764 783 763 784 0.93

5 9 0.008 0.48 10.6 0.0 3 21 836 854 834 855 0.91

6 9 0.017 0.99 9.6 0.0 2 23 918 939 917 939 0.98

7 9 0.0034 0.2 11.8 1.3 1 23 945 967 945 967 0.99

8 9 0.00058 0.035 14.2 0.7 1 23 1035 1058 1035 1058 0.96

9 9 0.36 22 5.4 0.5 2 20 1170 1188 1169 1190 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.0058	0.35	11.0	0.0	1	20	212	231	212	233	0.90
2	9	0.00025	0.015	15.3	0.8	1	23	288	310	288	310	0.98
3	9	0.045	2.7	8.2	1.0	2	21	361	380	361	381	0.92
4	9	0.043	2.6	8.3	2.9	2	21	764	783	763	784	0.93
5	9	0.008	0.48	10.6	0.0	3	21	836	854	834	855	0.91
6	9	0.017	0.99	9.6	0.0	2	23	918	939	917	939	0.98
7	9	0.0034	0.2	11.8	1.3	1	23	945	967	945	967	0.99
8	9	0.00058	0.035	14.2	0.7	1	23	1035	1058	1035	1058	0.96
9	9	0.36	22	5.4	0.5	2	20	1170	1188	1169	1190	0.91

Sequence Information

Coding Sequence: ATGTCACGACGCAAACAGTCGAACCCAAAGCCGTTGAATAAAGGAGATTGTTCCGATACCACAGAAGAGATGACCGTCGACAGCAGAGATTCCAAAGATTTAGGTTCACACGAACTGAGCGAGgagaaggagcagcagcaCGACTTCGAGGAGCTGccagaagaggaggaggacgaACATCCTAGCGAGGAGAACCAAACAAGCAACCACAGCTCCGACCAGCCCATGGAGACTGACATGGACCAAGTGGAGGCAGAAGATGCCGATCacgaggagcagcaacagcagcagaaggaggCTGACAACTCGACGACACCGCCGCGCAGTCCGACGCCGCAGCTGGTGCCAAAGCTGGAGCGGATGGAGCAGCCAGCCACAccgccatcagcagcagccacgcCCAGTCCCCCGCCCACACCCACACCTATAACTGCTGCGCTACCGAAGCTGCGGCTTAATGCATTGTTAGCCTCGGATCCAGCGCTCAAACCCGACGCCAAGGAGCTCAATCTGGCCGATGCTCGGCTGCTCGCTCCACCACCGCAGCTGTCCAAGCCGGAGCCGTCATCTTCTCAGAGTCTAGCTGaggcagccagcagcaatCTCGTTGAGCCGCTGCTGAAGCCGGCGCGCTTCATGTGCTTGCCCTGTGGAATTGCCTTCAGTTCTCCATCGACCCTGGAGGCGCATCAGGCTTACTACTGCTCACATCGCAACAAGGAGACGGACGAGGAGGCCGGCTCGGGCGATAAGCTGTCAGCTGCGGGAGGCGGTGGCGCCGCTGGCACCgggaacagcaacaacaatggcggAGGAAGCAGCTCGGAGCCACCGGCGAAGGTGGCGCGCACAGGAAAGCAATATGCGTGCACTCAGTGCTCCTACAGTGCCGACAAGAAGGTCTCCCTCAACAGGCACATGCGCATGCATCAGACCTCGCCAGCTCCCAGCCTGCCCAGCCTCGCCGGCCTGACTGCCAATGGCGTGGCAGCTGTCGGAGGAGTCGGAGTGGGAGTTGGAGGTGCTAGCGGAGTCGCGGCGGGTTCGCTCGAGGAGAGCTCTAGTCAACAAATCGATCGCTATTGCAGCGACTGTGATATCCGCTTCAACAACATCAAGACCTATCGCGCCCACAAGCAGCACTACTGCAGCTCCCGCCGCAACGACGGTCAGCTCACACCCAAGCCCGAGGCAGGCGTCGGTTCAGGCTCATCCGGCACTCCCGGCACAGCCACCCCGGTCGGTGCTGGCAAACTGAGTGGAGCGCACAGTCCACAGTCGCGGAACAAGACCCCGACTCCCGCCATGgtggctgctgccgccgccgctgcagctgctgctgcctcgtTGCAGGTGACGCCGCCACAGCCCTTCCTGGCACTGCCCACCAACCCGATCATAATTGTGCCCTGCTCGCTTATCCGCGCAGCCAGCCTCATTCCGGGACCGCTGACCACCTCGACTTCGGGCATCGTCAACCCGGAGTCCACTTGCTTCACCCTCGACAACGGCGCCTTGAAGCCGCTGGCCACAGCACTCAACATCAATGCGTTGGCCGGAAATGTGACTCCGACGCCGCCAATGCCCAGCAGCAATCAGCAACCGATTCCTGCCCTGGAACCAGAGCGTCAGTCAGCAAGCAACAGCGAAGCTGAGACCAAGAGCAGTCCCACTGAGCCCAAGCGCAAGGAAGCGGGAGGAGGCGCCACTCGCGAGTCTACCCCACTGGATCTCTCCCTGCGTCGTTCTCCTATCTCGGCGCTGTTGCAGCGTCAGCGTCTCGTGCGCTCCGCTGCCGCATTGCTCGAGGCAGAGGAGGCGCTCTTGGCTGCTGCAGGCAAAGAGAACCTGGAGAGCGGTGGTAGCGTTACCCCCGAGCAGATTGTGTGTGCTCCCTCGTTGCCCAGCAGTCCCTCGATGAGTCCCTCGCCCAAACGACGGGTCGTGAGTCCTCGCAGCTCCGGCGCTGGCAGCGCTGCCTCCATGTCGCCGCCCACTCTGGGCGTAGGTGTAGGTGTGCCACATCTGCTGGAGAATTTGCCACCGCTGCGCTCCATGCTGCCTGCGGACTTTGCGCTCTCCGAGTCCCTGCTGGCCAAGACCAACCCTGAGTTGGCGCTCAAGctggctgccgctgccgcagcggctgtggcaggcagcagcacTGCGGAGCTGGCCAGCAAACTGGGCTTCCCCACTGCACCTGGAGCCGGAAGCAACGCTCCAGCTGCGGCGACAGCCAATGCGCCAAGTGCACAGCCACAGATCTATGTGAAGCAGGGCGTGTCCAAGTGCAAAGAGTGCAATATTGTCTTCTGCAAGTACGAGAACTATTTGGCCCACAAGCAGCACTATTGCTCCGCCCGCAACCAGGAGTCGGGCGAGGGCGATGCCAAGAGCGCCAGCTCGCCGCCAAGCGGAGCAGCGACAGCGCAAGTTGGAGCTGGAGTGGGAGGAGCTGCCTCCGCGGCAGAGACTACGCCGGTGGCGTATCAGCAGCTGATCTGCGCTGCCTGTGGCATTAAGTACACATCGCTGGACAATCTGCGTGCGCATCAGAATTACTATTGCCCCAAGGGTGGCGCAGCAGCCACACCAGTTGCTGATCCCCCACAGCTGCCCAAGGAAAAGTGCGGCAAGTGCAAGACACTTCACGAACTTGGCCAACCCTGTCCACCTCCGGCTGCTCCCCAGCTGCCTCCACTTGCGGCAACCGCGGCCGCGTCGGGCGCCTCCTCGAACAGTGTCAACAAGTGTCCCGTCTGTGGTGTTATTAGTCCTACAGCAGCGTTGGCCAGGAAGCACATGGAGATGCATGGCACAGTGAAGGCGTTCCGCTGCAGCATTTGCCAGTACAAGGGCAACACGTTGCGTGGCATGCGCACTCACATTCGCACCCATTTCGACAAGAAGACGAGCGACGTGAACGAGGAGCACTACATGACTTGCATCTTCGAGGAGGATGCAGCTgccgcggctgctgctgctgcggctgcagctgttgctgcgacTCCCGTTGGACTCGGTTTGGATGTGCCGGTTGTGGCCTCGCCTCAGGAgcaactggagcagcagcagcacgcgCAACATCCGCCACAGATCTTCAATTGCGACTACTGCAACTATGCGTCTAGCTACAAAGGCAACGTGCTGCGCCACATGAAGTTGCTGCATCCACACGTGGCCATCAACTCGCCCTCGATTTCGCCAGAGACGCGGGACCAAGAAATCAATCCGCATGCCGAAGTGGCGCTCGTCAATGGCGATCGCGATTGCTCATCAGTAGCCAGTTTCCACATTAAATCGGAGCCTCTAGAGCAACCACCCGTGGCAGCAACGCTGAGCTTGGtgcatgacaacaacaactcaccCATTGGCAcaccacacactcacatcaAGGCCGAACCTCAGGACATAGGCATGGATGTATCGCCTCCTTCGCTGCCGCCACCGCCAGTGTCGAACTCGCCGCTGGGAAACAGCGCAGCGGCCGAGGCCATGAAGAAGTACTGCTCCACCTGCGACATATCCTTCAACTATGTCAAGACCTATCTGGCCCACAAGCAGTTCTACTGCAAGAGCAAGATGCATCGTCCCGAGGCCAACGATAGCCCCAGTCCCAATCACATGAATCACAATCACCTGGGTGCCACTGTACCGCTGCAGTCGCCCagcgagctgctgctgctccagaaGAACAAGGAGAATCTACAGGAGGCGGCCATTTGA
Protein Sequence: MSRRKQSNPKPLNKGDCSDTTEEMTVDSRDSKDLGSHELSEEKEQQHDFEELPEEEEDEHPSEENQTSNHSSDQPMETDMDQVEAEDADHEEQQQQQKEADNSTTPPRSPTPQLVPKLERMEQPATPPSAAATPSPPPTPTPITAALPKLRLNALLASDPALKPDAKELNLADARLLAPPPQLSKPEPSSSQSLAEAASSNLVEPLLKPARFMCLPCGIAFSSPSTLEAHQAYYCSHRNKETDEEAGSGDKLSAAGGGGAAGTGNSNNNGGGSSSEPPAKVARTGKQYACTQCSYSADKKVSLNRHMRMHQTSPAPSLPSLAGLTANGVAAVGGVGVGVGGASGVAAGSLEESSSQQIDRYCSDCDIRFNNIKTYRAHKQHYCSSRRNDGQLTPKPEAGVGSGSSGTPGTATPVGAGKLSGAHSPQSRNKTPTPAMVAAAAAAAAAAASLQVTPPQPFLALPTNPIIIVPCSLIRAASLIPGPLTTSTSGIVNPESTCFTLDNGALKPLATALNINALAGNVTPTPPMPSSNQQPIPALEPERQSASNSEAETKSSPTEPKRKEAGGGATRESTPLDLSLRRSPISALLQRQRLVRSAAALLEAEEALLAAAGKENLESGGSVTPEQIVCAPSLPSSPSMSPSPKRRVVSPRSSGAGSAASMSPPTLGVGVGVPHLLENLPPLRSMLPADFALSESLLAKTNPELALKLAAAAAAAVAGSSTAELASKLGFPTAPGAGSNAPAAATANAPSAQPQIYVKQGVSKCKECNIVFCKYENYLAHKQHYCSARNQESGEGDAKSASSPPSGAATAQVGAGVGGAASAAETTPVAYQQLICAACGIKYTSLDNLRAHQNYYCPKGGAAATPVADPPQLPKEKCGKCKTLHELGQPCPPPAAPQLPPLAATAAASGASSNSVNKCPVCGVISPTAALARKHMEMHGTVKAFRCSICQYKGNTLRGMRTHIRTHFDKKTSDVNEEHYMTCIFEEDAAAAAAAAAAAAVAATPVGLGLDVPVVASPQEQLEQQQHAQHPPQIFNCDYCNYASSYKGNVLRHMKLLHPHVAINSPSISPETRDQEINPHAEVALVNGDRDCSSVASFHIKSEPLEQPPVAATLSLVHDNNNSPIGTPHTHIKAEPQDIGMDVSPPSLPPPPVSNSPLGNSAAAEAMKKYCSTCDISFNYVKTYLAHKQFYCKSKMHRPEANDSPSPNHMNHNHLGATVPLQSPSELLLLQKNKENLQEAAI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00509368;
90% Identity: iTF_00553961;
80% Identity: -