Dnas001940.1
Basic Information
- Insect
- Drosophila nasuta
- Gene Symbol
- zfh1
- Assembly
- GCA_017165715.1
- Location
- Scf:172830-202919[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 9 0.0051 0.32 11.1 2.1 2 23 76 98 75 98 0.96 2 9 0.00079 0.05 13.7 0.1 1 23 296 318 296 318 0.97 3 9 1.3e-05 0.00082 19.3 0.6 2 23 332 353 331 353 0.97 4 9 4.8e-05 0.0031 17.5 4.9 1 23 362 384 362 384 0.99 5 9 0.0002 0.012 15.6 1.4 3 21 392 410 390 411 0.94 6 9 0.025 1.6 9.0 0.4 2 21 672 691 671 692 0.92 7 9 1.2e-05 0.00078 19.4 0.5 1 23 1057 1079 1057 1079 0.94 8 9 4.6e-05 0.0029 17.6 7.4 1 23 1085 1107 1085 1107 0.98 9 9 0.0023 0.15 12.2 4.3 1 21 1113 1133 1113 1134 0.96
Sequence Information
- Coding Sequence
- ATGTTGTCCTGTTTGGCGCCATCGTCTTCACGTTTTGGCCAAGAGGATAACATTATACAGCAGAGCATGCCATCGTCCACAGCCTTCTCCATGCAGTTTCCCTCTTTGGCGTCCACTTTGCACCACCATCAAGCACACAGCAAGCCCAGCAATGTGGCTGCCAGTGAAGAGCATGCCACGCATGCAACCAGCGCCACAGCGAATGCGGCAGATGACTATTTGGTCAAGTGCACGCAGTGCCACAAACGCTTCAATGAGTTTCAGTCCCTCAGCGAGCACATTGCCCGCGAGCATCCGCACGACAAGCTCAACTATGAGCCACTGCGTCAAGCTGGCGCTGCGCAGCCCGAGAGCGATGCCGAGGAGGATGAGCAAAGTAATTTGAGCAGCAGCAGTCGACGCTACAACAAATCGCCCTCAAATAACAACAACAACAACATTGAGACAGCCAAAAATCAAAACAACAGCAGCCAACAGCAATTGACATCGCCGCTCTGCTCACCTGTTGCCCAAGCACAGCAACAGCAGCAGCCACCGCCGCCGCCCAGCGATCTCTTTGCCCATCTGCCGCATCCTCCGCCACAGCTGCCCGCACATTTGCATGCTCAATTCATGGCCGCCGCCGCCTTGGCCATGCAATCGGCACGCTCCGCCAGCTCACCCAGCCACCCGCTACACCATCACCAACAACACCAACAGCAGCAGCAGCAGCAACACCATCAGCAGCAACAACAGTTGCCACAGCAAGCGGGACAGCTGTTGTTGCCGCCACCGCAAACGGGCAGCAACAGCAGCGTGGGCAGCAATTCAGCCTACGAGCTGGATCTGAGTGCGCCACGTTCCACCTCGAGTCCGGGCTCAACAACGGGCGATCTCAGCGCTGCCTTTCCCTGCATGCAATGCACGGCGGCGTTTGCCACACGCGAGCAACTCGAACAGCATCAGCTGCTGCACTCGCCCACAGGACAGCAGACGACACAGAATGTGGCACAGACCTGCAAGATATGCAACAAGGCATTCGCCAATGTCTATCGACTGCAGCGCCACATGATCAGCCACGATGAGTCGGCGCTGCTCCGCAAATTCAAATGCGGTCTCTGCGAGAAGGCCTTCAAGTTCAAGCACCATCTGAAGGAACATGTGCGCATTCATTCCGGCGAGAAGCCTTTCGGCTGCGACAAGTGTGGCAAGCGTTTCTCGCACTCCGGCAGCTTCTCCTCCCACATGACCTCGAAGAAATGCATCAGCATGGGCCTCAAGCAGAACAACGGCAGCAACAGCAATCAAAACAACGGCAACAACTCGAATTCCAATTCGCGGCAATTGCTCAAGAGTTTGGATAAAAACGGACGTTCGCCCACAGATCAAATGGCTGGCAAACGTGGCTGCAAATTGCCACTGGAGGCGACGAATCCTCTGCTGCCCAATCCCATGAACTATTTCGCTGGCGAAGCACAAGTGCCACAAGTTCCAGCTGGCGCTGGAGCTGCGGCCAATGCGGCTGCGCCGCCTTTCTATCCCAACTACAGTGCCATGAGCACAGCGTTGTTGGCGTTTCCCAATGCCTTCATGGCTGCTGCACTCGATCCACGCATGCATCCCTATAGCATACAGCGACTGCTGGAGCTGACAGCCGCACAACAGCATCAGCAGCAACAGTTGCATCGCGAAGAGCAACAGCAACTAGAGCAACAGCAACACTTGGAGCAACAGCAACCGTTGTATGAGCCCAGCAAGGAGGAGGAAGAAACGCCCGATGAGCCCAAGCTTGTGATGGACTTGGAGGAGTCGGAACTGAAGCCAACCACACCAGAATTGCCGGCAGCTGAACCCGTTGTGCCGCTGAAGCAGGAGCCAAGTCGCGAGGCGACGCCAGCGCTGCTAGAAAGTGCACCTGCCACGCCCCAAAACATCAAGCAGGAGGCACAAGAGCCGCAGGAGCAACAGGAGCCAGAACTGCAGCTGGAGGAACAAGAGGAAGAGCAGCAGCAGGTGACGACGCCACAAGAGTTGCGCTGCAGTCGCTGTGCCAAGCAGTTCAATCATCCCACAGAGCTCGTGCAGCACGAGAAAGTGCTCTGCGGTCTGATCAAAGAAGAACTCGAGCAGCACTATCAACAGCAACAACAACAACAGCAGCAGCAGCAACAACTGCAACAGCAACAACAACAACAGCAACATTCAAGCTTTGTGCTGCCCAGCGATGCTGAAGAGGAGGAGGAAGATGTGGAGGAGGAGCCACGTTCCATGCAGGATTACAACGCCGGAGGCAGCAGCGATAGCGGGGAGCGCAAAGTTCGTGTTCGCACCGCCATCAACGAGGAGCAGCAGCAACAACTCAAGCAACACTACGCACACAATGCTCGTCCAAGTCGCGATGACTTTCGCCTGATTGCCTCGCGTCTGCAACTCGATGCCCGTGTCGTCCAAGTGTGGTTCCAAAACAATCGTTCACGCGAACGCAAGATGCAGAGCTACAACAACGAGCCACAAGTGGCAGCCACAACAACAGTTGCACTAACAGCAGCTGCAGCGCCTTCCGCTGCCGATCAGCCGCTGGATTTGTCCGTGAAACGCGATGCTTCTCCGCTCTACGGACTTGCGCCACAACCCAGTGCTTTGAGTGTGCCTACAGCTGATTTCCCCGAGAGCATGGCCATCAATCTGAGCCGCAAGCTGTCCAGCTCGGCCTCGATGTCCCCAGCCTCGTTGTCGCCCTGCTCGGGCGCCTCGTCGCTGCAACAATCGGCAGCTGCTGCAGCCGCCGCTGCTTTGTACTTTGCGCCGCCCTCGCCACCGAGTCATCTGCATGAGGCAGTTCCTCCGTTGGCGCCACGCGGCCAACCCTTTGCCAACTTGCCGTCCTATCTGATGCCCCGGCTGCCCATGGAGGCGTTGTTCCAGATGCGCCCCGGCGGCGATTATGCGCCCAATCCGCTGATGAACAGTATTAAGCTGCCCGACTATCGCGGCACCAGTTTGAGTCCCGGTGGCAGCGAGAAACGTTCGTGGCGCGACGACGATTCGCGCATCTCGCACGACGATGATTACGTTTTGGCAGCCGCAGCGGCAGCTGCAGCTGGAGCAGGTCCGGGTGGATTGTTGCCACCGAAACCGAAGCGTGCCAAGGCCGAGACACATGGACATGCGGGTGATCCTGATCTGCCATTCGTGTGCGATCAGTGCGACAAAGCGTTTGCCAAACAGAGTTCCCTGGCACGCCACAAATACGAGCATTCCGGTCAACGACCCTATCAGTGCATGGATTGCCCCAAGGCCTTCAAGCACAAGCATCATCTGACGGAGCACAAGCGTTTGCATTCCGGCGAGAAGCCATTTCAGTGCTCCAAGTGCCTGAAGCGCTTCTCGCATTCGGGCAGCTACAGCCAGCACATGAACCACCGTTACTCCTACTGCAAGCCATACAGGGAATAG
- Protein Sequence
- MLSCLAPSSSRFGQEDNIIQQSMPSSTAFSMQFPSLASTLHHHQAHSKPSNVAASEEHATHATSATANAADDYLVKCTQCHKRFNEFQSLSEHIAREHPHDKLNYEPLRQAGAAQPESDAEEDEQSNLSSSSRRYNKSPSNNNNNNIETAKNQNNSSQQQLTSPLCSPVAQAQQQQQPPPPPSDLFAHLPHPPPQLPAHLHAQFMAAAALAMQSARSASSPSHPLHHHQQHQQQQQQQHHQQQQQLPQQAGQLLLPPPQTGSNSSVGSNSAYELDLSAPRSTSSPGSTTGDLSAAFPCMQCTAAFATREQLEQHQLLHSPTGQQTTQNVAQTCKICNKAFANVYRLQRHMISHDESALLRKFKCGLCEKAFKFKHHLKEHVRIHSGEKPFGCDKCGKRFSHSGSFSSHMTSKKCISMGLKQNNGSNSNQNNGNNSNSNSRQLLKSLDKNGRSPTDQMAGKRGCKLPLEATNPLLPNPMNYFAGEAQVPQVPAGAGAAANAAAPPFYPNYSAMSTALLAFPNAFMAAALDPRMHPYSIQRLLELTAAQQHQQQQLHREEQQQLEQQQHLEQQQPLYEPSKEEEETPDEPKLVMDLEESELKPTTPELPAAEPVVPLKQEPSREATPALLESAPATPQNIKQEAQEPQEQQEPELQLEEQEEEQQQVTTPQELRCSRCAKQFNHPTELVQHEKVLCGLIKEELEQHYQQQQQQQQQQQQLQQQQQQQQHSSFVLPSDAEEEEEDVEEEPRSMQDYNAGGSSDSGERKVRVRTAINEEQQQQLKQHYAHNARPSRDDFRLIASRLQLDARVVQVWFQNNRSRERKMQSYNNEPQVAATTTVALTAAAAPSAADQPLDLSVKRDASPLYGLAPQPSALSVPTADFPESMAINLSRKLSSSASMSPASLSPCSGASSLQQSAAAAAAAALYFAPPSPPSHLHEAVPPLAPRGQPFANLPSYLMPRLPMEALFQMRPGGDYAPNPLMNSIKLPDYRGTSLSPGGSEKRSWRDDDSRISHDDDYVLAAAAAAAAGAGPGGLLPPKPKRAKAETHGHAGDPDLPFVCDQCDKAFAKQSSLARHKYEHSGQRPYQCMDCPKAFKHKHHLTEHKRLHSGEKPFQCSKCLKRFSHSGSYSQHMNHRYSYCKPYRE
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00589739;
- 90% Identity
- iTF_00553641; iTF_00472530; iTF_00472266; iTF_00562679; iTF_00562372;
- 80% Identity
- iTF_00553641;