Basic Information

Insect: Drosophila albomicans
Gene Symbol: zfh1
Assembly: GCA_009650485.1
Location: NC:25893522-25923724[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.0053 0.32 11.1 2.1 2 23 76 98 75 98 0.96

2 9 0.00082 0.049 13.7 0.1 1 23 296 318 296 318 0.97

3 9 1.3e-05 0.0008 19.3 0.6 2 23 332 353 331 353 0.97

4 9 5e-05 0.003 17.5 4.9 1 23 362 384 362 384 0.99

5 9 0.0002 0.012 15.6 1.4 3 21 392 410 390 411 0.94

6 9 0.026 1.5 9.0 0.4 2 21 672 691 671 692 0.92

7 9 1.3e-05 0.00076 19.4 0.5 1 23 1061 1083 1061 1083 0.94

8 9 4.8e-05 0.0029 17.6 7.4 1 23 1089 1111 1089 1111 0.98

9 9 0.0024 0.14 12.2 4.3 1 21 1117 1137 1117 1138 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.0053	0.32	11.1	2.1	2	23	76	98	75	98	0.96
2	9	0.00082	0.049	13.7	0.1	1	23	296	318	296	318	0.97
3	9	1.3e-05	0.0008	19.3	0.6	2	23	332	353	331	353	0.97
4	9	5e-05	0.003	17.5	4.9	1	23	362	384	362	384	0.99
5	9	0.0002	0.012	15.6	1.4	3	21	392	410	390	411	0.94
6	9	0.026	1.5	9.0	0.4	2	21	672	691	671	692	0.92
7	9	1.3e-05	0.00076	19.4	0.5	1	23	1061	1083	1061	1083	0.94
8	9	4.8e-05	0.0029	17.6	7.4	1	23	1089	1111	1089	1111	0.98
9	9	0.0024	0.14	12.2	4.3	1	21	1117	1137	1117	1138	0.96

Sequence Information

Coding Sequence: ATGTTGTCCTGTTTGGCGCCATCGTCTTCACGTTTTGGCCAAGAGGATAACATTATACAGCAGAGCATGCCATCGTCCACAGCCTTCTCCATGCAGTTTCCCTCTTTGGCGTCCTCTTTGCACCACCATCAAGCACACAGCAAGCCCAGCAATGTGGCTGCCAGTGAAGAGCATGCCACGCATGCAACCAGCGCCACAGCGAATGCGGCAGATGACTATTTGGTCAAGTGCACGCAGTGCCACAAACGCTTCAATGAGTTTCAGTCCCTCAGCGAGCACATTGCCCGCGAGCATCCGCACGACAAGCTCAACTATGAGCCGCTGCGTCAAGCTGGCGCTGCGCAGCCCGAGAGCGATGCCGAGGAGGATGAGCAAAGCAatttgagcagcagcagtcgacgCTACAACAAATCGCCctcaaataacaacaacaacaacattgagacagccaaaaatcaaaacaacagcagccaacagcaattGACATCGCCGCTCTGTTCACCTGTTGCccaaaatcaacagcagcagcagccaccgccaccgcccaGCGATCTCTTTGCCCATCTGCCGCATCCTCCGCCACAGCTGCCCGCACATTTGCATGCTCAATTCATGGCCGCCGCCGCCTTGGCCATGCAATCGGCACGCTCCGCCAGCTCACCCAGCCACCCGCTACACCatcaccaacaacaccaacagcagcagcagcaacaccatcagcagcagcagcaacagttgccacagCAAGCGGgacagctgttgttgccgccacCGCAAacgggcagcaacagcagcgtggGCAGCAATTCAGCCTATGAGCTGGATCTGAGTGCGCCACGTTCAACTTCGAGTCCGGGCTCGACAACGGGCGATCTCAGCGCTGCCTTTCCCTGCATGCAATGCACGGCGGCGTTTGCCACACGCGAGCAACTCGAACAGCATCAGCTGCTGCACTCGCCCACAGGACAGCAGACGACACAGAATGTGGCACAGacttgcaaaatatgcaacaagGCATTCGCCAATGTCTATCGACTGCAGCGCCACATGATCAGCCACGATGAGTCGGCGCTGCTCCGCAAATTCAAATGCGGACTCTGCGAGAAGGCCTTCAAGTTCAAGCACCATCTGAAGGAACATGTGCGCATTCATTCCGGCGAGAAGCCTTTCGGCTGCGACAAGTGTGGCAAGCGTTTCTCGCACTCCGGCAGCTTCTCCTCCCACATGACCTCGAAGAAATGCATCAGCATGGGCCTCAAGCagaacaacggcaacaacagcaatcaaaacaacggcaacaactcGAATTCCAATTCGCGGCAATTGCTCAAGAGTTTGGATAAAAACGGACGTTCGCCCACAGATCAAATGGCTGGCAAACGTGGCTGCAAGTTGCCACTGGAGGCGACGAATCCTCTCCTGCCCAATCCCATGAACTATTTCGCTGGCGAAGCACAAGTGCCACAAGTTCCGGCTGGCGCTGGAGCTGCGGCCAATGCGGCTGCGCCGCCTTTCTATCCCAACTACAGTGCCATGAGCACAGCGTTGTTGGCGTTTCCCAATGCCTTCATGGCTGCTGCACTCGATCCACGCATGCATCCCTATAGCATACAGCGACTGCTGGAGCTGACAGCCgcacaacagcatcagcagcaacagttgcaccgcgaggagcaacagcaactagagcaacagcagcacttggagcaacaacaaccgttGTATGAGCCCAGCAGGGAGGAGGAAGAAACGCCCGATGAACCCAAACTTGTGATGGATCTGGAGGAGTCAGAACTGAAGCCAGCCAGTCCAGAGTTGCCTGCAGCTGAACCCGTTGTGCCGCTAAAGCAGGAGCCAAGTCGCGAGGCGACGCCAGCGCTGTTAGAAAGTGCGCCTGCCACGCCCCAAAACATCAAGCAGGAGGCCCAAGAGCCGCAGGAGCAACAGGAGCCAGAACTGCAGCTGGAAGAGCAAgaggaagagcagcagcaggtgacGACGCCACAAGAGTTGCGCTGCAGTCGCTGTGCCAAGCAGTTCAATCATCCCACAGAGCTCGTGCAGCACGAGAAAGTGCTGTGCGGTCTGATCAAAGAAGAACTCGAGCAGCactatcaacaacaacaacaacaacaacaacaacaacaacaacaacagcagcagcaacaactgcaacagcagcaacagcaacattcaAGCTTTGTGCTGCCCAGCGATGCTgaagaggaggaagaagaTGTGGAGGAGGAGCCACGTTCCATGCAGGATTACAACGCCGGaggcagcagcgacagcgggGAGCGCAAAGTTCGTGTTCGCACCGCCATCAacgaggagcagcagcaacaactcaaGCAACATTACGCACACAATGCGCGTCCAAGTCGCGACGACTTTCGCCTGATTGCCTCGCGTCTGCAGCTCGATGCCCGTGTCGTCCAAGTGTGGTTCCAAAACAATCGCTCACGCGAACGCAAGATGCAGAGCTACAACAACGAGCCAcaagtggcagccacaacaacagttgcaccaacagcagctgcagcgcctTCCGCTGCCGATCAGCCGCTGGATTTGTCCGTCAAACGCGATGCTTCTCCGCTCTACGGACTTGCGCCACAACCCAGCGCTTTGAGCGTGCCCACAGCTGATTTTCCCGAGAGCATGGCCATCAATCTGAGCCGCAAGCTGTCCAGCTCGGCCTCGATGTCGCCGGCCTCGTTGTCGCCCTGCTCGGGTGCCTCGTCGCTGCAACAatcggcagctgctgcagccgccGCTGCTTTGTACTTTGCGCCGCCCTCGCCACCGAGTCATCTGCATGAGGCAGTGCCTCCGTTGGCGCCACGCGGTCAACCCTTTGCCAACTTGCCGTCCTATCTGATGCCCCGACTGCCCATGGAGGCATTGTTCCAGATGCGTCCCGGCGGCGATTATGCGCCCAATCCGCTGATGAACAGTATAAAGCTGCCCGACTATCGCGGCACCAGTTTGAGTCCCGGTGGCAGCGAGAAACGTTCGTGGCGCGACGACGATTCGCGCATCTCGCACGACGATGATTACGTTTTGGCAgccgcagcggcagctgcagctggagcaggTCCGGGTGGATTGTTGCCACCGAAGCCGAAGCGTGCCAAGGCCGAGACACATGGACATGCGGGTGATCCTGATCTGCCATTCGTGTGCGATCAATGCGACAAGGCGTTTGCCAAGCAGAGTTCCCTGGCACGTCACAAATACGAGCATTCCGgTCAACGACCCTATCAGTGCATGGATTGCCCCAAGGCCTTCAAGCACAAGCATCATCTGACGGAGCACAAGCGTTTGCATTCCGGCGAGAAGCCATTTCAGTGCTCCAAGTGCCTGAAGCGCTTCTCGCACTCGGGCAGCTACAGCCAGCACATGAACCACCGTTACTCCTACTGCAAGCCATACAGGGAATAG
Protein Sequence: MLSCLAPSSSRFGQEDNIIQQSMPSSTAFSMQFPSLASSLHHHQAHSKPSNVAASEEHATHATSATANAADDYLVKCTQCHKRFNEFQSLSEHIAREHPHDKLNYEPLRQAGAAQPESDAEEDEQSNLSSSSRRYNKSPSNNNNNNIETAKNQNNSSQQQLTSPLCSPVAQNQQQQQPPPPPSDLFAHLPHPPPQLPAHLHAQFMAAAALAMQSARSASSPSHPLHHHQQHQQQQQQHHQQQQQQLPQQAGQLLLPPPQTGSNSSVGSNSAYELDLSAPRSTSSPGSTTGDLSAAFPCMQCTAAFATREQLEQHQLLHSPTGQQTTQNVAQTCKICNKAFANVYRLQRHMISHDESALLRKFKCGLCEKAFKFKHHLKEHVRIHSGEKPFGCDKCGKRFSHSGSFSSHMTSKKCISMGLKQNNGNNSNQNNGNNSNSNSRQLLKSLDKNGRSPTDQMAGKRGCKLPLEATNPLLPNPMNYFAGEAQVPQVPAGAGAAANAAAPPFYPNYSAMSTALLAFPNAFMAAALDPRMHPYSIQRLLELTAAQQHQQQQLHREEQQQLEQQQHLEQQQPLYEPSREEEETPDEPKLVMDLEESELKPASPELPAAEPVVPLKQEPSREATPALLESAPATPQNIKQEAQEPQEQQEPELQLEEQEEEQQQVTTPQELRCSRCAKQFNHPTELVQHEKVLCGLIKEELEQHYQQQQQQQQQQQQQQQQQQLQQQQQQHSSFVLPSDAEEEEEDVEEEPRSMQDYNAGGSSDSGERKVRVRTAINEEQQQQLKQHYAHNARPSRDDFRLIASRLQLDARVVQVWFQNNRSRERKMQSYNNEPQVAATTTVAPTAAAAPSAADQPLDLSVKRDASPLYGLAPQPSALSVPTADFPESMAINLSRKLSSSASMSPASLSPCSGASSLQQSAAAAAAAALYFAPPSPPSHLHEAVPPLAPRGQPFANLPSYLMPRLPMEALFQMRPGGDYAPNPLMNSIKLPDYRGTSLSPGGSEKRSWRDDDSRISHDDDYVLAAAAAAAAGAGPGGLLPPKPKRAKAETHGHAGDPDLPFVCDQCDKAFAKQSSLARHKYEHSGQRPYQCMDCPKAFKHKHHLTEHKRLHSGEKPFQCSKCLKRFSHSGSYSQHMNHRYSYCKPYRE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00589739;
90% Identity: iTF_00553877;
80% Identity: iTF_00472266;