Basic Information

Insect: Drosophila multiciliata
Gene Symbol: -
Assembly: GCA_037043605.1
Location: JBAMBF010000389.1:32066-35530[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.13 8.8 6.9 0.0 1 13 343 355 343 363 0.81

2 8 0.0004 0.027 14.9 1.8 1 23 702 725 702 725 0.95

3 8 0.00083 0.056 13.9 3.4 1 23 754 776 754 776 0.97

4 8 0.0001 0.0069 16.7 6.5 1 23 782 804 782 804 0.97

5 8 3.6e-05 0.0024 18.1 0.9 1 23 810 832 810 832 0.98

6 8 0.002 0.14 12.6 1.4 1 23 838 860 838 860 0.98

7 8 0.011 0.73 10.4 0.0 2 23 867 888 866 888 0.96

8 8 0.017 1.1 9.8 0.1 3 21 896 914 894 915 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.13	8.8	6.9	0.0	1	13	343	355	343	363	0.81
2	8	0.0004	0.027	14.9	1.8	1	23	702	725	702	725	0.95
3	8	0.00083	0.056	13.9	3.4	1	23	754	776	754	776	0.97
4	8	0.0001	0.0069	16.7	6.5	1	23	782	804	782	804	0.97
5	8	3.6e-05	0.0024	18.1	0.9	1	23	810	832	810	832	0.98
6	8	0.002	0.14	12.6	1.4	1	23	838	860	838	860	0.98
7	8	0.011	0.73	10.4	0.0	2	23	867	888	866	888	0.96
8	8	0.017	1.1	9.8	0.1	3	21	896	914	894	915	0.91

Sequence Information

Coding Sequence: ATGGCGGCTGCAGCTGTTGAGGATGGGCGAGAAAAATGCGGCAGCGTCTACACTTGGAACTGTGCTGGCGAACTCTATGGCATCGAGTGTGAGCTGTGCGAGGAACGACCCCTCTGTGCACTCGATGAGTTTGCCGAGCATATGGAGCTGTGGCACTCCGACTGGCAACAGGCGCCGGAAGATGAGCTCATGCAGGAGGTTCTCGCCGAACAGTCCAGCAGCAACTGCGAGGTCAACGAACTGAAACAGCAGCTGGTTCAAGAGCTTAACTCACTCGATAAACAGCAACCACAGCTGATGGACACATTTCAACTAAATGATCAAGTTCAGTTCAATGAGGATagtgGTTTACCCCGTGTGGAGACGCCAGGGAAGCTGACGACGGAGCATGTACAGCAGCTGATTGAGCTATATCGATCGCATCCGCGACTGTGGGATCAATCGCATCCAGAGTTTCGGGACGTGGAGCAGGGTCGCCAGTCGTGGCGTCAGATATCGGATGCGTGGAGTGCCCACTGCGGACGTGGCTTCAGTGTGACCGATGTGCGCATTCGGATCTCTACGCTGTGCCAACGATTCCTCAAGCAGCGCGAACGTATCGATGCCGAGGGTGACCTCGATCTCGATGAGAGCGCTAAGTTCGTCCATTACGATCAGATGCGTTTCCTGTGTGAGCAGCAGGCACTGCTTAAGCGCCAGGAGCACTTTGCACGCGAGAACCGCAAACTGCTCGAGATCTACGAGCACTATCCAATACTCTGGCACAATGCCCACAAGAGATTGCGCTGCGCCTCAACGGTGCAGAGGCGCCACGAAGCACATCGTGGCCTCCAGCTGGGGTTGCGCATGAGCGGCATTAATCTGTCCGGATTAGCGATGCAGCGACGACTCCAGTCGCTGAGGAAACGCTATCGCCTGGAGAAGATACGCTATCTGCACAGTGTCGTCGAGGGGAAACAATCCGAGTTTGTGTCCATCTTTGAGCATTATGCTGAAATGGAGTTTCTCCACAAGCACATCGATCCCTATGTCTGTGCTGGCTGTGGCAAGATCTTTGAGAACCTGATCGGCCATCAGGCGCATGTGCAGGATAGTTGCGAGGAGCAATCACTGGCTGCTGCCGACTGCAAACAGTTGACCGAATCGGAAGCGACACTGGGCGATCTTATggtgcagctggagcagcacgaattacagcagcagaagcagcagcaacagcagctggcggTCGGAGTTGaattggagcagctgcagggagtggagcagcaggagcagctggtgGCAGCAGTAATTACAACTGAGCTTTCCACGCCACTGCTGCATAGTCCAgcagaacagcagcaggcggaggaggaggagattGAGCCACTTCCTAAAAAGGAAGATTCGCACGGCAAGGAGTCCTTCTCCGAGGATAGCCAGTCGACGGGTGGGCAGCTACGTATGCGCCTCAGCCTGGAGTTGACCAATAAACTGATTGAGCTCTATCAATTGCATCCGAATCTTTGGGATCCCAATCATCTGGACTACCATGCGAGGAAACAACGACGCCAGGCCTGGCACAACATTGCCGCCCAGCTGAACACATTTGCCAGCTGCCCGGATCGCTTCAGCTGGCAGATGCTTCATCGCAAGCTCACCGATTATGTCAAGTACTATCGACGCGAACGCCAGCGGGAGGAGCTGGCGGTTGGAGGTGACGGCGAGGGCACCCGTTGGGTCTTCTATGCGGCGTTCAGTTTTATGGACGATGTGGTGCCGATAAATCGTGTGCTGCAGAAATCATTGCAGCAGCGCGACAGCAATCTGAAGATCATCCAGGTTTATCAGAGCTACGAGCAGCTATGGTGCACCACACATCCGGATTATACGAAACGCAAGCAACGCCTGCGACACCTCGAGTCTCTGTGCACCCGCCTACAGGAGGAGTGCAATCTGCAGATAACCGTTGAGCGTTTGAAGAGTCGTCTGATCGAGTTCCGCTGCCAATATCGTCAGTGCAAAGAGGCGCGCCAGGCGGCGCTTCAGCGCAATAATGCCACCTGGCAACCGAGCTACGAGTATTATGCGGCGCTGCAGTTCCTCGAACTACATGTGTCGCCCTTTAACTGTGAACGGTGCACGGCGAGCTTTAAGCGACGCAGCGACTATCTCCGACATCAGAGCAACGTTCACTTGGATCAGCAGCTTAATGAGATGCAGCCCTTTCCGGTCCGGCGTCGCGTGCCACGTGGCACGAATGCCACCAATCCACTGGAGCACATCTGCCACATTTGCGCGATGAAATTCTCGTTGCGCACCAGCCTTCAGGCGCATCTACGTCGCCATCTGGGGCAGCGGACACACTGCTGCACCGACTGCCCTAAGAAGTTCTTCAATTCGACCTCGCTGCGGGTGCATCAGCGCAGCCACACCAAGGAGCTGCCGTATGTGTGTGAGCATTGTGCCCGGGGCTTTGTCAATGCCAGTAAACTGAATCAGCACGTCAAGCGGCATACGGAAAAGCGGGATTACCCGTGCACTCGCTGCGAAAAGGCCTTCTATACGGCCCACGAGCGAGATCGACATCTGCGCGCCCATCTCAACATCAGGGACAAGGTGTGTCCGTACTGCAGTCGAGCCTTTGTCGTCGGCAGCGCCTATTATGCCCATCTCAATCTGCATCGGGGCGAGAAGCGGTATGGCTGTGCCGCATGTGGCAAGCGATTCGCTCAGTATGCGGGTCTCTACAAGCATCGCAAGCGCTGCACAATCGCCCAGCTGCAGGAGAAGTGa
Protein Sequence: MAAAAVEDGREKCGSVYTWNCAGELYGIECELCEERPLCALDEFAEHMELWHSDWQQAPEDELMQEVLAEQSSSNCEVNELKQQLVQELNSLDKQQPQLMDTFQLNDQVQFNEDSGLPRVETPGKLTTEHVQQLIELYRSHPRLWDQSHPEFRDVEQGRQSWRQISDAWSAHCGRGFSVTDVRIRISTLCQRFLKQRERIDAEGDLDLDESAKFVHYDQMRFLCEQQALLKRQEHFARENRKLLEIYEHYPILWHNAHKRLRCASTVQRRHEAHRGLQLGLRMSGINLSGLAMQRRLQSLRKRYRLEKIRYLHSVVEGKQSEFVSIFEHYAEMEFLHKHIDPYVCAGCGKIFENLIGHQAHVQDSCEEQSLAAADCKQLTESEATLGDLMVQLEQHELQQQKQQQQQLAVGVELEQLQGVEQQEQLVAAVITTELSTPLLHSPAEQQQAEEEEIEPLPKKEDSHGKESFSEDSQSTGGQLRMRLSLELTNKLIELYQLHPNLWDPNHLDYHARKQRRQAWHNIAAQLNTFASCPDRFSWQMLHRKLTDYVKYYRRERQREELAVGGDGEGTRWVFYAAFSFMDDVVPINRVLQKSLQQRDSNLKIIQVYQSYEQLWCTTHPDYTKRKQRLRHLESLCTRLQEECNLQITVERLKSRLIEFRCQYRQCKEARQAALQRNNATWQPSYEYYAALQFLELHVSPFNCERCTASFKRRSDYLRHQSNVHLDQQLNEMQPFPVRRRVPRGTNATNPLEHICHICAMKFSLRTSLQAHLRRHLGQRTHCCTDCPKKFFNSTSLRVHQRSHTKELPYVCEHCARGFVNASKLNQHVKRHTEKRDYPCTRCEKAFYTAHERDRHLRAHLNIRDKVCPYCSRAFVVGSAYYAHLNLHRGEKRYGCAACGKRFAQYAGLYKHRKRCTIAQLQEK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01322149;
90% Identity: iTF_00499112;
80% Identity: -