Dmul000628.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila multiciliata
Gene Symbol
Hr39
Assembly
GCA_037043605.1
Location
JBAMBF010000103.1:4780294-4783340[-]

Transcription Factor Domain

TF Family
SF-like
Domain
zf-C4|SF-like
PFAM
AnimalTFDB
TF Group
Zinc-Coordinating Group
Description
The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 3 0.38 3.2e+03 -2.9 13.6 32 206 29 220 21 223 0.53
2 3 2 1.7e+04 -10.4 26.7 46 147 214 335 202 373 0.28
3 3 2.4e-101 2.1e-97 327.1 13.0 1 408 507 898 507 898 0.92

Sequence Information

Coding Sequence
ATGCCAAATATGTCGAGCATTAAGACGGAGCAGAGTGTTTCACCCGGTGCCAGTGGCAGCTATCAGCTGCCTGAAAACATGTCGACGGCGACAGTGTTGCCAGCGTcgcagccgctgcagcagcaacagcagcagcagcatcagcagcgtcACAATGTCTCCGTGACGAATATCAAATGTGAACTGGACGAGCTGGCGACGCCAACGAATGGCAATCTGGTGCCGGTCATAGCCAactataataatcataatcacaatcacaatcacaatcatAGCGGCAGCCTGCGCATTCCCCTCGGTGGCAATGGGGATGAGTCCGACTCGGATGCGGAGCTGGCCAACATTGAGAATCTAAAGGTGCGGCGACGTGCGGCAGACAAGAATGGTCCGCGTCCCATGTCCTGGGAGGGAGAGCTGAGCGAGAACGAAACGAATGGCGGCGCCGTCGGGGACGAGGAGGAGCTCATGGAAACGGAAACGGTAATCAAGAGCGAggtgagcagcagcaccaacagcagcagcagtgccacAACGTTGGCCAGCAGTCAAGTGAACGCCATGTTGCAGCCCATCAAAACCGAACTGGAGCACATAGCCGGTgagatgcaacagcaacagcaacttcagcagcaacaacaacaacagcagcagcaacaacagcagcaacagcagcagcagcaacaacaacagcagcagcaactgcaacagcaacagctgcagctgcaacagcaacaacaattgctgccaCTGAAGCAACAGAGCTATGCACCGAacaacaaactgaaactggCGCCAACGCAAAGTGATCCcatcaatttgaaatatgagccaacaacaacgacaacatcatCGCTGCTCTGCGACAGGAGCAAGTCGAATAGTGGCGGCcatttgccgctgctgcccgCCAATCCCAGTCCCGATTCTGCCATACATTCCGTCTACACGCACAGCAGCCCCTCCCAATCCCCGTTGACGTCCCGCCACGCCCCCTACACGCCATCGCTGAGCAGAAACAACAGCGATGCGTCGCACAGCAGctgctacagctacagctccGAATTCAGTCCCACCCACTCACCGATTCAGGCGCGTCATGCGCCACCCGCTGGCGTCGCTGCCTTGTTTACGGGCAATGCAAATGGCGGTGCACTGCATCATCATAGTGTGCTCTATCGGCCACTGAATGTGGATGCCGCACAGGAGGCGCAAAACCTGAGCATGGATGCGGGTGGTGCTGCGCTGGATGCCAGCGCCACGTTGGCCGCCTCGCCGGCGGGCATCTCGCGTCAGCAGCTGATCAATTCGCCGTGTCCGATTTGTGAGGATAAAATCAGTGGCTTCCACTATGGCATCTTCTCGTGCGAGTCGTGCAAGGGCTTCTTCAAGCGCACCGTCCAGAATCGCAAgaactatgtgtgtgtgcgcggcGGTCCCTGCCAGGTGAGCATCTCGACGCGCAAAAAGTGTCCCGCCTGCCGTTTCGAGAAGTGCCTGCAGAAGGGCATGAAATTGGAGGCGATTCGAGAGGATCGCACCCGAGGCGGTCGCTCCACGTATCAATGCTCCTACACGCTACCCAATTCAATGCTCAGTCCGCTGCTCAGTCCGGATCAGGCGGCAGCCGCTGCCGCCGTTgtcaatcagcagcagcagcagcatcagcagcaacatcagcaacaccaacagcagcgacttcaacaacatcaacagcaacaacaacagcaacaacagcagcagcagcaacatggtCCACTCAATGGctttggtggtggtggctcCAACTCGCTTCCAGCGAGTCCCAGTCTCGGCGGGGCATCCATCAAGACGGAGCTAGCGGAGCAGCTTAATCATCATACGTTATCAACGCGTGCCTCAAGCATTCCAGCCCTGCTGCAGGAAATCATGGATGTTGAACATCTCTGGCAATACACAGATGCGGAATTGGCACGCATTAATCAGCCGCTGTCCTCATTTGCAACTGGCGGCTCATCGTCGAGCGGCACAGGCGGTTCAAGTTCCGCCGGACAGCATACGGGCAATGCACAACAAATGACCAATCCACTGCTGGCCAGTGCTGGTCTCTCATCCAACGGCGAGAACGCCAATCCCGATCTGATTGCACATCTCTGCAATGTGGCCGATCATCGCCTCTACAAGATCGTCAAATGGTGCAAAAGTTTGCCGCTCTTCAAGAACATCTCGATTGACGATCAGATCTGCCTGCTCATCAACTCGTGGTGTGAACTGCTGCTCTTCTCCTGCTGTTTTCGTTCCGTCGACACGCCCGGCGAGATCAAGATGTCACAGGGCCGAAAGATTACGCTGGCACAGGCTAAAACCAATGGCTTGCAGGCTTGCATTGAGCGCATGTTGAATCTGACGGATCATTTGCGACGCCTGCGCGTGGATCGCTACGAATATGTTGCCATGAAGGTAATCGTGCTGCTGCAGTCCGACACAACGGAACTGCACGAGGCAGTCAAGGTGCGCGAGTGCCAGGAGAAGGCGCTGCAGGGTTTGCAGGCCTACACGCTGGCCCATTATCCCGATACGCCGTCCAAGTTTGGTGAGCTGCTCCTGCGCATACCCGATCTGCAGCGCACGTGTCAGCTGGGCAAAGAAATGCTGACGATCAAAACGCGTGATGGTGcagattttaatttgctgATGGAACTGCTGCGCGGAGAACATTGA
Protein Sequence
MPNMSSIKTEQSVSPGASGSYQLPENMSTATVLPASQPLQQQQQQQHQQRHNVSVTNIKCELDELATPTNGNLVPVIANYNNHNHNHNHNHSGSLRIPLGGNGDESDSDAELANIENLKVRRRAADKNGPRPMSWEGELSENETNGGAVGDEEELMETETVIKSEVSSSTNSSSSATTLASSQVNAMLQPIKTELEHIAGEMQQQQQLQQQQQQQQQQQQQQQQQQQQQQQQQLQQQQLQLQQQQQLLPLKQQSYAPNNKLKLAPTQSDPINLKYEPTTTTTSSLLCDRSKSNSGGHLPLLPANPSPDSAIHSVYTHSSPSQSPLTSRHAPYTPSLSRNNSDASHSSCYSYSSEFSPTHSPIQARHAPPAGVAALFTGNANGGALHHHSVLYRPLNVDAAQEAQNLSMDAGGAALDASATLAASPAGISRQQLINSPCPICEDKISGFHYGIFSCESCKGFFKRTVQNRKNYVCVRGGPCQVSISTRKKCPACRFEKCLQKGMKLEAIREDRTRGGRSTYQCSYTLPNSMLSPLLSPDQAAAAAAVVNQQQQQHQQQHQQHQQQRLQQHQQQQQQQQQQQQQHGPLNGFGGGGSNSLPASPSLGGASIKTELAEQLNHHTLSTRASSIPALLQEIMDVEHLWQYTDAELARINQPLSSFATGGSSSSGTGGSSSAGQHTGNAQQMTNPLLASAGLSSNGENANPDLIAHLCNVADHRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLLFSCCFRSVDTPGEIKMSQGRKITLAQAKTNGLQACIERMLNLTDHLRRLRVDRYEYVAMKVIVLLQSDTTELHEAVKVRECQEKALQGLQAYTLAHYPDTPSKFGELLLRIPDLQRTCQLGKEMLTIKTRDGADFNLLMELLRGEH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00575636;
90% Identity
iTF_00595983;
80% Identity
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