Basic Information

Insect: Drosophila mulleri
Gene Symbol: ken1
Assembly: GCA_035047565.1
Location: JAWNPK010000049.1:4726908-4729268[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.011 0.86 10.3 4.3 3 23 247 267 245 267 0.96

2 12 0.00021 0.016 15.7 0.9 1 23 273 298 273 298 0.94

3 12 0.00012 0.0095 16.5 0.2 2 23 306 330 305 330 0.93

4 12 0.0025 0.19 12.4 4.8 1 23 340 362 340 362 0.97

5 12 0.0002 0.015 15.8 1.9 2 23 370 391 369 391 0.96

6 12 0.0069 0.53 11.0 0.5 1 23 397 419 397 419 0.97

7 12 0.0015 0.11 13.1 2.0 1 23 425 448 425 448 0.98

8 12 0.0013 0.098 13.3 1.9 1 23 454 476 454 476 0.97

9 12 0.0018 0.14 12.8 0.8 2 23 483 504 482 504 0.98

10 12 0.00035 0.027 15.0 0.8 1 23 587 610 587 610 0.95

11 12 0.19 14 6.5 1.7 1 19 616 634 616 638 0.73

12 12 0.00031 0.024 15.2 2.1 1 23 644 667 644 667 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.011	0.86	10.3	4.3	3	23	247	267	245	267	0.96
2	12	0.00021	0.016	15.7	0.9	1	23	273	298	273	298	0.94
3	12	0.00012	0.0095	16.5	0.2	2	23	306	330	305	330	0.93
4	12	0.0025	0.19	12.4	4.8	1	23	340	362	340	362	0.97
5	12	0.0002	0.015	15.8	1.9	2	23	370	391	369	391	0.96
6	12	0.0069	0.53	11.0	0.5	1	23	397	419	397	419	0.97
7	12	0.0015	0.11	13.1	2.0	1	23	425	448	425	448	0.98
8	12	0.0013	0.098	13.3	1.9	1	23	454	476	454	476	0.97
9	12	0.0018	0.14	12.8	0.8	2	23	483	504	482	504	0.98
10	12	0.00035	0.027	15.0	0.8	1	23	587	610	587	610	0.95
11	12	0.19	14	6.5	1.7	1	19	616	634	616	638	0.73
12	12	0.00031	0.024	15.2	2.1	1	23	644	667	644	667	0.97

Sequence Information

Coding Sequence: atgaaTGAGGGGAGTGAATACTCCATACATTCGTTATGCCGCATTTGTTTGAACCATTTGCGAAACGATCCGGCATACGACCTGTTTCTCGTCCCTGGCTTGGCCAAGAAactttgtgtgtgtacttCGCTTTCAGTAGAAGAGCACGATGGCTTCCCAAAGAACATCTGCGGTTCTTGCTACACCCAACTCAACGCCTTGCACGGATTCCAAAAGCTTTGTGTGGACTCTGTGCAAAAGTTCCAGGAAATGCTCGCTAGCAAATACTTTGTACCCGTCATGGCCGATGTTGACAAAGTTGATCTGATGAATGTTACTGCCCCAGATGGAGATATGGACGAGGATCGAACTAACTTTGATCCCCTTCTCAATACTAAAATTGAGGTAGTGGAAACTGAAGATGTTTTTAAAATGCTGGATGATGTGGATAAAGAAGTTGAAGAGGTTGAGAAGGAGCTGTCTAGTGAGGCTGAGTTCGAGAATGATGACGACCCGGAATTTGAAGTAAATAGCAGCGACTCAAATGACGCGGTTCCTCTGTCCCGTTTGAAAACTGTTACTAGAGCATCGAAGGCCAAAAGTAAACCTGTGGTAGAAGACAAAGATAAAGATAAGGATAAAGACTCCTCGGACTTCGAATGGGAAATGGATAATGACTTTGATAAAGAAGAACCTAAAACCAAATCAAGAAGAAAACGCGTGTCAAAACCCAAAGTCAAACAGGATGATGCCATTGATTGCCACATCTGTAACGAAAAATTCAAGAGCACTAAGCTTTATGACGAACATATGAAACATCATAACGATCTACTGCCATTCCAATGCACTGTGGAGACCTGTAAGAAAGGCTTCACAACATCTGGTGGACTACGCCTTCATATGGACCATGCTCATTCGGAACTGTCAGAAGTTCACGCCTGTTCTGTTGAGGGATGTGGCATGACATTTCCTCGACCGGTTTTACTCACGAACCATTTGAAAAAAGTTCACAACATCATTACATCTCGAGCTAAAGATCATCCTTGTACTGTGTGTGAGAAAGTCTTTCGTTGTTCAACGGCCCTTAAGAAGCATATGTACAAGCATACTGGAGAGGAGAAGCCAATTTCATGCAACATCTGCAACAAACGTTTCCACATAAACAGCGAGCTGAAGGATCATCTGTTGCGTCATGCCGGTGTGAAGAATCATGTTTGCCCTTACTGTGGTGTGGGTAAGACAACTCGACAGGAGTGGAACAAGCACATATTGACGCATACGAAGGAAAAACAGTTCCAGTGTGATCAATGCGATCATTCGTCCCACAACAAACAAGCTCTGGCAAATCACATCAAGGTTGTGCATATGAAGATTAAGAATTACGCCTGTCAGTACTGCGGCAAGACATTCGGCAAGTCGTATGCCTGCAAAGTCCACGAAAGAATCCACACTCGCGAAAACTGCTCTCAGTGCAATATCTGTGGCAAGGTTTTACTTTTTGAGAGGAGCTTGACCAAGCATTTGAAGACTCATGAGAAGCGTGAGCTTCGCGCAACAGCTACAAAAGGGCGTGGTAAAGATGGTGCGCAGAACAGCCAGGAGACAAGTGAACCTGTGGAGATGAAGCTTATACCAACAGAGCCACCTAAGCCGAAAAACGGAAACAGGCTAGAGCGGGTAGATATATCAGAGTTGGCCGGTACAGCTGTCAATCCCATTCCAACTGTTTCTGTGGCATCCTGGTCACCCCAAGTGAACTTTACTAAGAAGGAGGGGCAGCACATTTGCCCtggatgtgggcgtggctttaACCATATTGGCAACATGAAGATTCACTTCAAAATTGTACACTTAAAGGTGAAAGATTTCGCCTGTCGCTTCTGTCCAAAGCGCTTTTCAAAGGCACAAATCTTACAGCATCACGAATGGACGCACACCGGCGAAAAGCCTTTCCCATGCAAGTATTGTGGCAGACACTTCCGACAGGAGAAAGTGATGAAAATACATGCGAGAAGGGTGCACGAGAATCCGAAGAAACCAGAAAGAGAGGCTAAGCCAAAAGAACCGAAGCCTCCAAAAGATCCTAATAGAGAGAAACGACCGAAGATGAATCTCAACGAGAAACCGCCCAAGATTCTTGATGAATATCAAGATCCTGCAGCAGAGAGGGCAGCAGCAAGGGCTGCTCTGCTTGCCCAACAGAAGGAGGAGTATGAAGCTAAGCAAAGGGCGGAAGAGGAAGCGCGTAAGATTCAAGAGGCTGCATGCGCACAACTTCATATGCTACAGAAAGAACAGCTTATTAACAAGCTACCCAGTGATAGCTTTCAAGTAAAAAAACCCGAAACTGGCATCAGTGTGGACGATCTTAAAGGAGAATAG
Protein Sequence: MNEGSEYSIHSLCRICLNHLRNDPAYDLFLVPGLAKKLCVCTSLSVEEHDGFPKNICGSCYTQLNALHGFQKLCVDSVQKFQEMLASKYFVPVMADVDKVDLMNVTAPDGDMDEDRTNFDPLLNTKIEVVETEDVFKMLDDVDKEVEEVEKELSSEAEFENDDDPEFEVNSSDSNDAVPLSRLKTVTRASKAKSKPVVEDKDKDKDKDSSDFEWEMDNDFDKEEPKTKSRRKRVSKPKVKQDDAIDCHICNEKFKSTKLYDEHMKHHNDLLPFQCTVETCKKGFTTSGGLRLHMDHAHSELSEVHACSVEGCGMTFPRPVLLTNHLKKVHNIITSRAKDHPCTVCEKVFRCSTALKKHMYKHTGEEKPISCNICNKRFHINSELKDHLLRHAGVKNHVCPYCGVGKTTRQEWNKHILTHTKEKQFQCDQCDHSSHNKQALANHIKVVHMKIKNYACQYCGKTFGKSYACKVHERIHTRENCSQCNICGKVLLFERSLTKHLKTHEKRELRATATKGRGKDGAQNSQETSEPVEMKLIPTEPPKPKNGNRLERVDISELAGTAVNPIPTVSVASWSPQVNFTKKEGQHICPGCGRGFNHIGNMKIHFKIVHLKVKDFACRFCPKRFSKAQILQHHEWTHTGEKPFPCKYCGRHFRQEKVMKIHARRVHENPKKPEREAKPKEPKPPKDPNREKRPKMNLNEKPPKILDEYQDPAAERAAARAALLAQQKEEYEAKQRAEEEARKIQEAACAQLHMLQKEQLINKLPSDSFQVKKPETGISVDDLKGE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00532579;
90% Identity: iTF_00540555;
80% Identity: -