Basic Information

Insect: Drosophila mulleri
Gene Symbol: hang
Assembly: GCA_035047565.1
Location: JAWNPK010000045.1:2065544-2077258[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 0.31 24 5.8 1.0 3 23 532 553 531 553 0.93

2 17 0.89 69 4.3 3.2 3 22 660 679 658 679 0.89

3 17 0.00066 0.051 14.2 3.3 1 22 780 801 780 803 0.90

4 17 0.065 5 7.9 0.1 2 21 815 834 814 835 0.93

5 17 0.00077 0.059 14.0 0.2 2 23 976 998 975 998 0.95

6 17 0.0022 0.17 12.5 0.1 1 23 1006 1029 1006 1029 0.96

7 17 0.00017 0.013 16.0 0.2 2 23 1115 1136 1114 1136 0.97

8 17 0.00032 0.024 15.2 2.9 2 23 1243 1265 1242 1265 0.97

9 17 0.025 1.9 9.2 0.2 2 23 1274 1296 1273 1296 0.95

10 17 0.0013 0.1 13.2 0.1 1 23 1309 1332 1309 1332 0.97

11 17 0.00014 0.011 16.3 1.1 1 23 1375 1397 1375 1397 0.99

12 17 0.0021 0.17 12.5 0.9 1 23 1405 1428 1405 1428 0.96

13 17 0.055 4.2 8.1 0.3 2 19 1436 1453 1435 1454 0.94

14 17 2.9e-05 0.0023 18.4 0.4 3 23 1551 1571 1550 1571 0.98

15 17 0.0056 0.43 11.2 0.1 1 23 1606 1628 1606 1628 0.97

16 17 0.00066 0.051 14.2 0.6 2 23 1721 1743 1720 1743 0.93

17 17 0.0071 0.55 10.9 0.3 3 23 1799 1819 1799 1819 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	0.31	24	5.8	1.0	3	23	532	553	531	553	0.93
2	17	0.89	69	4.3	3.2	3	22	660	679	658	679	0.89
3	17	0.00066	0.051	14.2	3.3	1	22	780	801	780	803	0.90
4	17	0.065	5	7.9	0.1	2	21	815	834	814	835	0.93
5	17	0.00077	0.059	14.0	0.2	2	23	976	998	975	998	0.95
6	17	0.0022	0.17	12.5	0.1	1	23	1006	1029	1006	1029	0.96
7	17	0.00017	0.013	16.0	0.2	2	23	1115	1136	1114	1136	0.97
8	17	0.00032	0.024	15.2	2.9	2	23	1243	1265	1242	1265	0.97
9	17	0.025	1.9	9.2	0.2	2	23	1274	1296	1273	1296	0.95
10	17	0.0013	0.1	13.2	0.1	1	23	1309	1332	1309	1332	0.97
11	17	0.00014	0.011	16.3	1.1	1	23	1375	1397	1375	1397	0.99
12	17	0.0021	0.17	12.5	0.9	1	23	1405	1428	1405	1428	0.96
13	17	0.055	4.2	8.1	0.3	2	19	1436	1453	1435	1454	0.94
14	17	2.9e-05	0.0023	18.4	0.4	3	23	1551	1571	1550	1571	0.98
15	17	0.0056	0.43	11.2	0.1	1	23	1606	1628	1606	1628	0.97
16	17	0.00066	0.051	14.2	0.6	2	23	1721	1743	1720	1743	0.93
17	17	0.0071	0.55	10.9	0.3	3	23	1799	1819	1799	1819	0.98

Sequence Information

Coding Sequence: ATGGTTGCCCGCTGctcagcgacgacgacgacgacgacgatgactcTCTGGACTGCGCCCCCGGCAACGACATCATCATCTACGTCggcgtcgtcgccgtcgccgttgtcgACACGTTGCTGCTGCGTGTGCTTGGTGCTTGGTGCTGGCACTAGGGCAAAGACTTTTGGTGGTGTTCCTGCCTCGGTGGCACTTGAGAAAGAGATGTGCCCAACAGGATGTCGCCGTGCGGGCGGCTTGatCACGCCACTGGATCGTCTGTCGCTTCATATTTGCCATGCCTGCATCAGCTATTTGAACTCCTGGCAGAGCTTTAAGAATCGCTGCCTCAGCTCACAGTCgaagcagcggcagtggctgGACAGCGATAAAAGCAAGCAGCAGACGCTACTGGGGTACTTGGATTTGAACAAAACGGAGAATGGCAGCTCCAttgaacaacagcagcaacaacatcaacaattgcagcagcagcagctcgaatCGAATATCGATTCGGCAACGATTGCAGCTGAAAAGGCATCCGCCAACATTTTGGATGGCATACCGTCGTTGAAGAAACGCAAATCGTTAACAGTTTATGTGAGTCCAAAGCAACAgcttcaacagcaacaacaacagctacagcagcagcagcagcagcagcaacaacagcagcagcaggtgcagcatACAGCAAGAGCAACGAGCGCGGCGGCGGAATCTCAGCAAACGCTGCAGACCCTTCTATTGCAGGTGCCctcagcggcggcagcattgGCGACGACGTcaacccagcagcagcagcagcaacagcaacagcgcaagtatcaacagcatcagcaacgttgcaagcagcaacattaccaccaacaacatcaacaacaagcgcagcagcagcatcagcgctTGAGTCGCATTCGTCAGCCGCGGCGCCAGCAACAGGCGACAATGTCCGGCCAGAGATTGGTAAAATTTAAGCCGAAATTGTTTATGCCACTGGATATAGCGGTGCCACCGTTGCCACCACTGTTGCCAAcgccgtcgcagcagcagcagccgactgacactgttgctgctggtgctaaATTGGcgccgttgcctttgccgttgccgctgccacttGATTTTAGCCAGAATCCGAATCCgaatcaaaatacaaatgcGAGTCAGAGTCAGCAGAAACACGGCAgcctgttgccgttgccgttgccagtACCAGTGTCATTGCCGCCGTCGACGCCGcagttgccgccgctgccggcTGCCACAATGACCAGCAACACCGCTGCGCCTAGTGCTGTCTCTgtcgcagccacagccgcagtcACGACTCCTCTGCTTATGCCGCCGCTGCCCGCCGTGCCAATCAAGGATGAGCCCATTGACGATACGGACGATGACTTTCAAATGAAGTGCATAGACGAATCCGACGATATGATGGATCCCACAATGTTCCTAGAGCGCTCCGAGCACGAGGGCGATGTGCCACTAATGACCTCCGACTATGATTACACGGCGCAACACGGCGTGACGGCGGTTGCGGCGGCGGCATCGCTGCCCGCCAGCGCGGTTGCAAACGTGGCCGCCGCCGGCGACTCGAAGGTGGCCAGCTGTCGGGCTTGCAGTCTGCAGTTCTCGACGCGCGCGAACGCCCGACGCCACGAACGTAATCTGCATCCGAATCTGTTTCAATTGTCGACAGATTCACCCAACAATACGCCCATCACAAAACCGACGCCGGCCCTGGCCGCCGCTCTGGAAATTCAGCGTgccgcagcggcggcggcagccacCGCAGAGGCAACCAAAGCCGCCGCCGGCGGCAACATATCAGCGCAAAAGTATCGCCAGGTGGTAATGAATACGTTCATCAAATGCGAAAACGGCGGATTCGACTACGACAATCCAGAGCAATATCAGCATCTGCTCACCCGCGACAAAGTCGATTTCATACAGGAGAACAACGAGTTTCTGGAGCAATACCAGACGATGACGTGTCGCTGCTGCAATAAGTACTTCAACACCTACAAGAACTTCATGGCGCACGTGCGCAAAAAGTATCCGCTGCTGCCGCGCAATCTGTGCTTCAACTGCCTCAAGATGAACGACTCGAAGGCGCTATTCATATCGCATCTGAAGAAGCGCAACTGCATCAATCTGTACCGCGTGCTCAACGCGCTGCGCCTCAAGCAGCCGAACTTTTCGCACGCCAACGCATCTGGTGTGGCTGTCTCGGCCGACTTGAGTGCTGGCcaagcggcagcggctgcagctgcatctgcGTCAGCTGGACACGAGACCTCATCGGAGCGGCCAGAGAAGCTGCGCGCCAAGGAGCTGTTGGTGAACAAGCTGTATGAGTGCAAACTGTGCCCGAAGGGCTTTCGCACCAAGCACGAGTTCCGCACCCACGTGTACGACAAGCATGCGGATGTGCAGCGCAAGGACAACAATTCGATACAGTGCACCTTCTGTGGCCTGGACTTTGCCGATCCCGTGGACCGCCGGCGCCACTACAACAACATGGAGTGCATTGTGCGGCTGCGCTGCATGACCTGTGATGCCAAGCTGGAGACGCATCAGCGTTTTCTCGACCACGTCTACCAGGACCATCTGGGCGGCGTGAGCAGCGATAATGCCTCGACGGCCAACAGCGGCGGCATGGATCATTCCCCGGGCAAACGCAGCCTGCTGGGCGCCTTGGGCATCGGCATAAGTCAGTCATCGAATGATGAGTCGCGCAGCAGCAtccacaacaataacaatgccgCGGAAGCGGCCTTCACCTCGACACCGAAGCCATCTGGAGGAGCGGCAGGCGGCGCCGGCGGCACCGGcggcacagctgcagcagcgacaggaGCAGCAAtcggtggcggcggcagctcCACATCCGGCAGTCGTGAGGCACCCAAATCGCAGTATTTCTCCCGCATGCCACAGGTGTGCCCGATCTGTGGGCAACagtacaacaactacaacaacgtGCTGCGCCACATGGAATCGAAGCATCCCAATAAGCTGCCCGAAACGTACAAGTGTGTGCGCTGCGGCCTGGGCTATCCGCGAATCTCCTATCTGCGCGAGCACATGATCAATGTGCATGGCGTGGACAAGAATCGCCATTCGGGCGGCTTTGAGTACATTGTGAATGCGGATGCAGTGAAGCTGGCGGACGGCAGCATGCCCAACGTCTACACGGGCCGTTATGATTATGTGATGAAGGATCTGATGTCAATAACAAATGGTGGGACACTcgatgaggatgaggaggaaAGCGGCAGCGTTGCCAAAAAGATGCGATtggacgacagcagcaacaacagcagcatcaacatgaGCATTGCCAACCAGCAGAAGGAGTGCCTCATCTGCAATGCGGTgttcagcaacaacattggCTTATCGAATCACATGCGCTCGCATTATACGGCCGCAACGGCAACGAATGCAGCGCTGGCGGCTGCCAATCGCATGACGCCCAAATCTTTGACAATTACCGCAACGCCGCCATTGGATACGACGGCGGCAACGTCGACGAGCGCCgcggcagctggagcaggagttggcggaggcggaggcggaggcacGGGCGCGACAAGTGCAGCTGGGGCCGGCAGTGGAGCTGGAGGATCAACAACAGGCAGTGGACTACCGCCCGCCATGGTGCATCAGACGCCACAGGAGCAGGCCGTGTTCCGGCGCAGTCTGGACCAGGCGGCGGATCGTCGCTTTCGGCGCATGCGCTGCCGCATCTGCCAGCGGCGGTTCAGCTCGAAGAAATCGTATCGCTATCACATGCTCACCGACCATCAGGTGCAGAACGTGCAGTTCATCAAGTGCAAGCTCTGCAATGCGGAGTTCGCCTACGAGAAGGGCCTGAAGGTGCATCTGTTCAAGGTGCACGGACGGGCCATCAAGGACGAGATGATTGTGAAGCAGTTCGAGTGCGACATCTGCTCCATTGTCTACAGctcggagctggagctgcagcagcacaagcgCAGCGTGCACAAATCGCACGATGCTGCCTCCAAATCGTCGGCAACCAAATCATCTACCGCTACCTCAGCTGCTGAACTGGCGGACACATCGGGTACGGGCGGGGCCGGAGCGGGCGCCGTCCTGCCGCTCTACTGGTACCAGTGCAAGTACTGCCCCTCCAACTTCAACACCAACAAGAAGCTAGCCATCCACATCAATTCGCATGACGAGTTCGATTCGAATGATTACTCGTGCAAGGATTGCGGCAATGTCTACAGCGGACGCAAGAGCCTCTGGGTGCATCGCTATAAGAAGCATCCGCAAGTGCCGGATCCAGTGGAGTGCACGCTCTGCCGCAAGATGTTCTTCGATCGGCAGATGCTGGAGAATCATACGCCCACCTGCAACCGGAAGCCCATCACTGCCACCGGCGCCCATCAGCAggatcagcaacagcaacaccagcaccaacaccaacaacagcagcagcagcaacagcaacgcgcCATATTCAAGCACAAAACTggcgacgatgacgatgaggaggaggatgaTCAGCTGATGCTGGTGGACGATGGCGGCAtgggcagcgacagcaacggtGGCAATGCGGCGGCCACCAGCGCCGCCAATCCAAATACGTTAAGTGCGAGCACAATGAAGATACGCATACCGGAGGTGGCGTGCACCATTTGCGGGGCACGCTTCACCGACCAGGAGATGTTCACCAAGCACATACAGAAGCACGAACAGGATCTGTATGTGGACAATCCGCTGGCGGCCATGTTCGATGATGGCCCCGCCGACGTTGGCCAATTCAAGGTGGAGCGCCAGAACGAGAATGGGGAATATGCGTGCGATTTGTGCGCCAAGACGTTCCCCCAGGTGATTGCGCTCAAGGTGCATCGCAAGTGGCATTTCAGAGGTGATAGCAAGCAGAATCTCATCATCGACGGCGAAGCGACAACgctgaacagcagcagcagcagcagcaacaacaacaacaacaacaacaacaacaacaattcgctGAGCTCCTCATCGATGCTACGCGAACTGCATGCAGTGGGCCTGATGCccaaccagcaacaacaccagaagcaactgcaacagcaacaacaacaacagcagcagcagcagcggaacaACACGTCGAGCAGCTCGAGCAAGTCGCTGAAGCGGAAACGTGAGCTGAAATGCGAGTACTGCGCCTCCACATtcattagcaacaacaacctgcGACGCCACATGTACGAGCTGCACAAGCACGAGGTGAGCAATCTGCCGGAGCCGCCGGTGATTGAGGTGGACGAGCCGCTGACGTGCCGCCGCTGCGGCGATATACGCTTCGATACCAAAGAGCAGTGGATCGAGCACAAGCTGGCGGACGCCAAAGTGGTGCGTCCCTTCTGTCCATTCCAATGGGGCTGTGACCTGTGCGGCGAGTACTTGTCGCGCAAGGAGAAGCTCATCAATCATATTAACAATCATCTCAAAGAGGATGTGATAGTGCCGGTGGCGACAGCCAGCAAAGCGCCCAACAAGGCAAAGACGGCAGCAgaaacatcagcagcaactgcaactgcaacagcaacagcaacggctgcAAAGGGCATAGTGCGagtggcggcagcagctggcggcaGAGTGAGTAAGGGTAAACagctggaggagcagcagaCAATGAAGGTGGcaacgaagcagcagcagcagcagcagaaggatgaggagcagcaacagcaggcatCAAATGATGATCATGCAGAGcaggatgatgatgacgatgaggaggaggatgaTGGCAGTGATATGGATGaagatgatgacgatgagaGCGACAGCGGGGAAGGGGAGAGCACGagtgctgatgatgatgaggaggacgatgatgacgatgagggCGAtgttgacgacgacgacgacgacgatgacgacgaagAAGATGTGGATGGCGATGTTGTTGaacagcaattgctgcaacaaaaacaacaacaacagcagcagcagcaacaacaacaacagcagcaacaacaacagcaacaaaacctcaatagcaacagcaatagcatcGCTGccaacgatgatgatgacgatctCATTGAGGAAGTCATCGAGGACGATGGCATTGTCGAGGAGCTGGACGACGAAGAGGACGATGACGATGGCAATACAACCGACGAGCaccagcagctggcagccaatagcaagcagcagcagccgagacGCCTCAACTTTGACTATTCCCGCTCGGACAGCGCCAAGCTGAACGGCAATGGGAAACAgacgccgcagcagcagctcggcgCGGCCAAGTCAAAGGGGGGCAGTCGGCGGTGCTGGTGA
Protein Sequence: MVARCSATTTTTTMTLWTAPPATTSSSTSASSPSPLSTRCCCVCLVLGAGTRAKTFGGVPASVALEKEMCPTGCRRAGGLITPLDRLSLHICHACISYLNSWQSFKNRCLSSQSKQRQWLDSDKSKQQTLLGYLDLNKTENGSSIEQQQQQHQQLQQQQLESNIDSATIAAEKASANILDGIPSLKKRKSLTVYVSPKQQLQQQQQQLQQQQQQQQQQQQQVQHTARATSAAAESQQTLQTLLLQVPSAAAALATTSTQQQQQQQQQRKYQQHQQRCKQQHYHQQHQQQAQQQHQRLSRIRQPRRQQQATMSGQRLVKFKPKLFMPLDIAVPPLPPLLPTPSQQQQPTDTVAAGAKLAPLPLPLPLPLDFSQNPNPNQNTNASQSQQKHGSLLPLPLPVPVSLPPSTPQLPPLPAATMTSNTAAPSAVSVAATAAVTTPLLMPPLPAVPIKDEPIDDTDDDFQMKCIDESDDMMDPTMFLERSEHEGDVPLMTSDYDYTAQHGVTAVAAAASLPASAVANVAAAGDSKVASCRACSLQFSTRANARRHERNLHPNLFQLSTDSPNNTPITKPTPALAAALEIQRAAAAAAATAEATKAAAGGNISAQKYRQVVMNTFIKCENGGFDYDNPEQYQHLLTRDKVDFIQENNEFLEQYQTMTCRCCNKYFNTYKNFMAHVRKKYPLLPRNLCFNCLKMNDSKALFISHLKKRNCINLYRVLNALRLKQPNFSHANASGVAVSADLSAGQAAAAAAASASAGHETSSERPEKLRAKELLVNKLYECKLCPKGFRTKHEFRTHVYDKHADVQRKDNNSIQCTFCGLDFADPVDRRRHYNNMECIVRLRCMTCDAKLETHQRFLDHVYQDHLGGVSSDNASTANSGGMDHSPGKRSLLGALGIGISQSSNDESRSSIHNNNNAAEAAFTSTPKPSGGAAGGAGGTGGTAAAATGAAIGGGGSSTSGSREAPKSQYFSRMPQVCPICGQQYNNYNNVLRHMESKHPNKLPETYKCVRCGLGYPRISYLREHMINVHGVDKNRHSGGFEYIVNADAVKLADGSMPNVYTGRYDYVMKDLMSITNGGTLDEDEEESGSVAKKMRLDDSSNNSSINMSIANQQKECLICNAVFSNNIGLSNHMRSHYTAATATNAALAAANRMTPKSLTITATPPLDTTAATSTSAAAAGAGVGGGGGGGTGATSAAGAGSGAGGSTTGSGLPPAMVHQTPQEQAVFRRSLDQAADRRFRRMRCRICQRRFSSKKSYRYHMLTDHQVQNVQFIKCKLCNAEFAYEKGLKVHLFKVHGRAIKDEMIVKQFECDICSIVYSSELELQQHKRSVHKSHDAASKSSATKSSTATSAAELADTSGTGGAGAGAVLPLYWYQCKYCPSNFNTNKKLAIHINSHDEFDSNDYSCKDCGNVYSGRKSLWVHRYKKHPQVPDPVECTLCRKMFFDRQMLENHTPTCNRKPITATGAHQQDQQQQHQHQHQQQQQQQQQRAIFKHKTGDDDDEEEDDQLMLVDDGGMGSDSNGGNAAATSAANPNTLSASTMKIRIPEVACTICGARFTDQEMFTKHIQKHEQDLYVDNPLAAMFDDGPADVGQFKVERQNENGEYACDLCAKTFPQVIALKVHRKWHFRGDSKQNLIIDGEATTLNSSSSSSNNNNNNNNNNNSLSSSSMLRELHAVGLMPNQQQHQKQLQQQQQQQQQQQRNNTSSSSSKSLKRKRELKCEYCASTFISNNNLRRHMYELHKHEVSNLPEPPVIEVDEPLTCRRCGDIRFDTKEQWIEHKLADAKVVRPFCPFQWGCDLCGEYLSRKEKLINHINNHLKEDVIVPVATASKAPNKAKTAAETSAATATATATATAAKGIVRVAAAAGGRVSKGKQLEEQQTMKVATKQQQQQQKDEEQQQQASNDDHAEQDDDDDEEEDDGSDMDEDDDDESDSGEGESTSADDDEEDDDDDEGDVDDDDDDDDDEEDVDGDVVEQQLLQQKQQQQQQQQQQQQQQQQQQQNLNSNSNSIAANDDDDDLIEEVIEDDGIVEELDDEEDDDDGNTTDEHQQLAANSKQQQPRRLNFDYSRSDSAKLNGNGKQTPQQQLGAAKSKGGSRRCW

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00476771;
90% Identity: -
80% Identity: -