Dmon008832.1
Basic Information
- Insect
- Drosophila monieri
- Gene Symbol
- -
- Assembly
- GCA_035047585.1
- Location
- JAWNPJ010000074.1:4823388-4827547[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 14 2.3e-05 0.0018 18.7 0.5 1 23 163 186 163 186 0.96 2 14 0.0031 0.25 12.0 2.8 2 23 235 257 231 257 0.88 3 14 0.69 55 4.6 0.6 1 23 361 384 361 384 0.91 4 14 0.42 34 5.3 5.0 3 23 435 456 433 457 0.94 5 14 0.00027 0.022 15.3 0.9 1 23 522 545 522 545 0.92 6 14 9 7.1e+02 1.1 0.0 2 14 564 576 563 580 0.82 7 14 0.0002 0.016 15.8 3.1 2 23 596 618 596 618 0.97 8 14 0.012 0.93 10.2 0.0 1 23 723 746 723 746 0.94 9 14 0.0014 0.11 13.1 0.2 1 23 777 800 777 800 0.92 10 14 0.0023 0.18 12.4 1.5 2 23 850 872 849 872 0.95 11 14 0.022 1.7 9.3 2.1 1 23 963 986 963 986 0.91 12 14 0.012 0.96 10.1 1.0 1 21 1038 1058 1038 1059 0.95 13 14 6.9 5.5e+02 1.5 0.1 3 23 1099 1122 1097 1122 0.73 14 14 0.45 36 5.2 2.5 1 23 1140 1164 1140 1164 0.92
Sequence Information
- Coding Sequence
- ATGGAAGGAATGGATCTGTGGACCTCGATGTTCTCCTCTGACTTCGACGAGCCGGAGGACGGGGTGGAGGGAGAAGCTGGTCTGGAGGGGGAGGACGGCGAGCAGTACGGCAATGGAAATGGTAATTCGGATCTTCTGGATGCCGACATGGGTGATGACGACATCCTGGATGGCGAGGAAGAGGacagggaggaggaggactacGACGACGACGGGGAGggggaaaataaagaaaagagcTCCGGACCCGATCCCGACGATGATGCCATCTTCGACTTTGAGTTGCAGCCCATGATTAGCTTGTCGGAGCACCCGGAGCAGCAATCGTCGTCATTGGAAGACGCTGGGGCCCCAATGCGAGGCCAGGCGCTGCCCGGCTCCCAGGGACGTAACCCCAATGCCGGCTATCCACAGCGTCCAACTACCTCGCAGATTAACGCCACGGACGAAAACGGAGTGCCCATCAACTACGAGCTGGGCGTTGTCTACATTTGCCCGGCCTGCGGCGCGGAGTTCCGGCAGCAGGACCACTGGAAGCGGCACATGAACCAAATGCACAAGTACAACACCTTGCGGGGCCTCAACTTCCTGCCGGTGGACAAGCTGTATCATCGGTGTCAGGAGTGCCACAAGCGGATTGCGATGCACAGTCGGGAGAATCTGCTGAAGCACAAGTTCACCCATCTGCCGTACAGGTGCACCAAGTGCTACATTTGCAAGCGGGAATACAAGTACAGGCAAGATCTTATGGTGCACTTGAGATTGGTGCACTGCGAAGAAGTGGTGGCCATGATGCGGGGCGGCTACAATGCAGCTGGCCGCAAGACCCGAGTCCGGGAGTCTCGCACCGAACAAATGCAGCGGGAGGAGGGATTCCCCCAAGACCAAGGCATGGATCGCATTGAGGTGCGCAACGAGGTACTCGAACCGGACGCAGAAGAGTCGCATGTGGTGGAACAACCAGTAGCCAGGCAGCCAGTAGTACCCGAAGAGGTGCGTCCTGTCAGCAGGATGAAGAAGTCGGAGGACGAGACTGAGGAATTTCAGCTCGCGGCGGAGCTGTGCGAGGACTACATACATTTTATGTGTCCGGATTGCAGCGACGAGTGCGGCAGCCTCAAGCAGTGGCGCCGGCACATAGAGTTCGCTCACGACTTCATGAGCCGGCGAGGACTCAACTTCCAGAGCAGTGCCGACATGCAGATGCAGTGCCTCGAATGCAAAAAGATCGTAACCCCGAACACCACCCAAACTCTGCGGGCGCACAAGTTCACTCATCTCCCGAATCCGGAATGGATGCACTGCAAGCTCTGCTACAAGGGTTTCTCGGACCACGTCAAGGTGGTGAAGCATCTGCTGCGGGAGCACCACATGGACACTCTAATGCCAGAGCGTCCGGGGAATATCACAGCCACCAGCCAGGCAGACGACGAATTCGGCGGAGAGGGACGAAAAGGAGAGGGGAACGGGGATGCGTTAGACGACGAGTCGCCCTATTTTGCGGATGCGCCCAGACGGGGTGGACGCATCAGCAGTGACGACATGTTCGAGCCGTTTATAGACTATCTCTGCCCGCAGTGCGGCAAGGAGTTCCGCGAGAAGAAGCACTGGCGCACCCACGTGGTCATGGTGCACGGAATGAACGACCTGTCGAAGCTGAACTTCAATGTGATAGACGAACGGAAGCTGAAGTGCCTCGAATGCGACAAGATCATCACCAATGCGTACGGCATCCAGAATGCGcagcagcacaggatcacccACTTGCCGTTCAAGGCCTATGCCAGGTGCACCAAGTGCCACAAGTCGTACACGGACAGGAAGGGTCTGGTTAAGCATCTGGCCACCTACCATCGCATTAGCGACATGCCTCGCAGATCGGCCGGCGGCGGCAGTCTGGGAGGAGGAGAGTCAGGTGGCGGCGGAGAACTTCCCCCGTTGCCCCCCGCTCCGAAGCAGCCCCGAAAGCAGATCGTCACGGTGGCCAATGAGACTTACGAAATAATCTACCTGGACGACCACGAGCCAGCCGTTGAGGAGGACAACGACTTTGGGGAGCAGATGCAGGCGGAGGAAGAAGACTACCTCCCGACTCCGATTGCCCCTCCGTCGCCACCAATGCTGCCTCCTGCAGCAGCAGACGCTTCGCCAAACAAGGAACAACGCTACAAATGCGTCCTCTGCCCTGAGGCCTTCGTTTCCCAGGCAGCCGCTAAGCAGCACAGACTCGAAGCGCACTTCAAGATTCGGAAGAGGTTGCGCAGCCACCAGCCGACGCAGGACGCGGAAGGGTTCGCTCCGCTGCCGACGGTGGAGCAGAACTACATCTTCCTGTGCCCCTCCTGCGGCATGGAGTACAAGACGCAGTTCGAGTGGCGGCGCCACATCAACGACGTCCACAGCTTTGACAAGCGCGAGTATCTGAACATGCGGCAGCTGGACAAGTACCGCTACCAGTGCACCCAgtgcaaggacgttgtgagcAACTCGAAGCTGAAGGGCCTGCAGGACCACCACTTCCGTCACCTGCCATACCGCTTGTACTTGAAGTGCCTCATCTGCGGCACCTGCTACAATCACAAGCCGAACATCGCGGCGCATCTGCGGGCGCGGCACAACATCTTCGAGAGGGGGGCGCCGGTGATGGTCACCAAGCCGTCCAAGATGTACCACCGCTATCGGGAGGTCGACAGAGAAAAGGCCCGACTTCCGTCACCGATTCCTGTGCCGGAATCACCACCCAGCTgttcgtcctcctcctcggggGCGGCCATGAGTCGCACCCTGAAGCCCCAGCCAGGGGCGTTGCCCGTCCGACCCGCTGGCCTGAACACCCTGGAGGATAGCATCTCGTATCACAATGCCGTGGACTTGGACTTCATTACGTACTTCTGCCCGAAGTGCAACCAGAACTTTGACTCGCACGCCTTCTGGCGCAAACACATCGTGGAGAAGCACAACTTCAATAGCCGCGAGGGGCTGAACTTCCGGCAGCTGGATAATCACCACTACCTCTGTCTGGAGTGCTACAAGCGGGTGACAGTGACCCACACGAAGGGTGCCATTGGGCAGTTGCAGTCGCACAAGTTCCGCCACCTGCCGCACCGCTCCTTCAAGTGCTTGACCTGTGGCGGGGAGTTCGTGCGCAAGCAGATGTTCTTCAAGCATCTGAATCGGGACACGAATCGCTGCGACAATCACCCGCAGCTGGAGCTGGACgacgaggagcaggagcaggagcacgATCAGGATCAGGAAGGAGCGGTGGCCATTCGGTCTTTGTACCAGCTGGCGTGTCCCCAGTGCGGCGATGGCTTCACCACGGTGAAGAGGACCGGATGGAAGGAGCACATCAATGTCTACCACAGTCTCACCAAGCTGGACCTGCTGCACATGATCAAGGTGGACGTGGATCGCTATCGCTGCAACGACTGCAATGAGGAGATTCGGACCACTCGGCTGCGCGAGCTGCAGCATCACCGCTTCCAGCACCTCCCCCACCCTGCCTATGTGCTCTGCAGGCTATGCGACGAGAATGAAGATGGCTCCGAATCGGGAGGCTGCCGGCTGCACAGTCTGCAGGATCTGAAACAGCATGTCCTGGACAGCCACAAGGCAGCTAAGGAAAAGGACTCAATGCTCGCTAAGATCCGGGATCACATGCGCAAGGAGGAGCAGGAAGACGTAGTGCCAACTGTGGACGATGAAGACAACCAGACTGGTCTCGACTCAGGTCCATACATGCCATTGCCCCCGCACCTGCTCGACGACGGGGACGACATGGACTTTGAGGATCAATATCTGCTGGGATAG
- Protein Sequence
- MEGMDLWTSMFSSDFDEPEDGVEGEAGLEGEDGEQYGNGNGNSDLLDADMGDDDILDGEEEDREEEDYDDDGEGENKEKSSGPDPDDDAIFDFELQPMISLSEHPEQQSSSLEDAGAPMRGQALPGSQGRNPNAGYPQRPTTSQINATDENGVPINYELGVVYICPACGAEFRQQDHWKRHMNQMHKYNTLRGLNFLPVDKLYHRCQECHKRIAMHSRENLLKHKFTHLPYRCTKCYICKREYKYRQDLMVHLRLVHCEEVVAMMRGGYNAAGRKTRVRESRTEQMQREEGFPQDQGMDRIEVRNEVLEPDAEESHVVEQPVARQPVVPEEVRPVSRMKKSEDETEEFQLAAELCEDYIHFMCPDCSDECGSLKQWRRHIEFAHDFMSRRGLNFQSSADMQMQCLECKKIVTPNTTQTLRAHKFTHLPNPEWMHCKLCYKGFSDHVKVVKHLLREHHMDTLMPERPGNITATSQADDEFGGEGRKGEGNGDALDDESPYFADAPRRGGRISSDDMFEPFIDYLCPQCGKEFREKKHWRTHVVMVHGMNDLSKLNFNVIDERKLKCLECDKIITNAYGIQNAQQHRITHLPFKAYARCTKCHKSYTDRKGLVKHLATYHRISDMPRRSAGGGSLGGGESGGGGELPPLPPAPKQPRKQIVTVANETYEIIYLDDHEPAVEEDNDFGEQMQAEEEDYLPTPIAPPSPPMLPPAAADASPNKEQRYKCVLCPEAFVSQAAAKQHRLEAHFKIRKRLRSHQPTQDAEGFAPLPTVEQNYIFLCPSCGMEYKTQFEWRRHINDVHSFDKREYLNMRQLDKYRYQCTQCKDVVSNSKLKGLQDHHFRHLPYRLYLKCLICGTCYNHKPNIAAHLRARHNIFERGAPVMVTKPSKMYHRYREVDREKARLPSPIPVPESPPSCSSSSSGAAMSRTLKPQPGALPVRPAGLNTLEDSISYHNAVDLDFITYFCPKCNQNFDSHAFWRKHIVEKHNFNSREGLNFRQLDNHHYLCLECYKRVTVTHTKGAIGQLQSHKFRHLPHRSFKCLTCGGEFVRKQMFFKHLNRDTNRCDNHPQLELDDEEQEQEHDQDQEGAVAIRSLYQLACPQCGDGFTTVKRTGWKEHINVYHSLTKLDLLHMIKVDVDRYRCNDCNEEIRTTRLRELQHHRFQHLPHPAYVLCRLCDENEDGSESGGCRLHSLQDLKQHVLDSHKAAKEKDSMLAKIRDHMRKEEQEDVVPTVDDEDNQTGLDSGPYMPLPPHLLDDGDDMDFEDQYLLG
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00615746;
- 90% Identity
- iTF_00476216;
- 80% Identity
- -