Basic Information

Insect: Drosophila ananassae
Gene Symbol: -
Assembly: GCA_017639315.1
Location: CM029943.1:13990338-13994481[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 2.1e-05 0.0016 18.7 0.5 1 23 162 185 162 185 0.96

2 14 0.0028 0.21 12.0 2.8 2 23 234 256 230 256 0.88

3 14 0.022 1.7 9.2 1.3 1 23 358 381 358 381 0.92

4 14 0.27 20 5.8 2.9 3 23 432 453 430 454 0.94

5 14 0.00029 0.022 15.1 1.1 1 23 519 542 519 542 0.92

6 14 8 6.1e+02 1.1 0.0 2 14 561 573 560 577 0.82

7 14 0.00018 0.013 15.8 3.1 2 23 593 615 593 615 0.97

8 14 0.0014 0.1 13.0 0.4 1 23 714 737 714 737 0.93

9 14 0.0013 0.097 13.1 0.2 1 23 768 791 768 791 0.92

10 14 0.002 0.16 12.4 1.5 2 23 841 863 840 863 0.95

11 14 0.02 1.5 9.3 2.1 1 23 955 978 955 978 0.91

12 14 0.011 0.83 10.2 1.0 1 21 1030 1050 1030 1051 0.95

13 14 6.2 4.7e+02 1.5 0.1 3 23 1089 1112 1087 1112 0.73

14 14 0.4 31 5.2 2.5 1 23 1130 1154 1130 1154 0.92

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	2.1e-05	0.0016	18.7	0.5	1	23	162	185	162	185	0.96
2	14	0.0028	0.21	12.0	2.8	2	23	234	256	230	256	0.88
3	14	0.022	1.7	9.2	1.3	1	23	358	381	358	381	0.92
4	14	0.27	20	5.8	2.9	3	23	432	453	430	454	0.94
5	14	0.00029	0.022	15.1	1.1	1	23	519	542	519	542	0.92
6	14	8	6.1e+02	1.1	0.0	2	14	561	573	560	577	0.82
7	14	0.00018	0.013	15.8	3.1	2	23	593	615	593	615	0.97
8	14	0.0014	0.1	13.0	0.4	1	23	714	737	714	737	0.93
9	14	0.0013	0.097	13.1	0.2	1	23	768	791	768	791	0.92
10	14	0.002	0.16	12.4	1.5	2	23	841	863	840	863	0.95
11	14	0.02	1.5	9.3	2.1	1	23	955	978	955	978	0.91
12	14	0.011	0.83	10.2	1.0	1	21	1030	1050	1030	1051	0.95
13	14	6.2	4.7e+02	1.5	0.1	3	23	1089	1112	1087	1112	0.73
14	14	0.4	31	5.2	2.5	1	23	1130	1154	1130	1154	0.92

Sequence Information

Coding Sequence: ATGGAAGGAATGGATCTGTGGACTTCGATGTTCTCCTCTGATTTCGATGAGCCAGAGGACGGGGCGGAGGGTGAAGCTGGTCTGGAGGGGGAAGATGGCGAGCAGTACGGCAATGGGAATGGAAATTCGGATCTTTTGGATGCCGACATGGGCGATGACGACATCCTGGATGGTGAGGAAGAGGACAGGGAGGAGGAGGACTACGACGACGATGGGGAGGGGGAGAATAAGAGGAAACGCTCCGGCCCCGATCCCGACGATGATGCCATCTTCGACTTTGAGTTGCAGCCCATGATTAACTTGTCGGAGCAGCCGGAGCAACCGTCGTCGCTAGAAGACAATGGGGCCAGCATGCGAGGCCAGTCACTGGCCGGCTCCCAGGGACGTAACCCAAACGCCGGCTATCCACAGCGGCCAACTACCTCGCAGATTAACGCCACGGACGAGAACGGAGTGCCCATCAACTACGAGCTGGGCGTTGTCTACATTTGTCCTGCGTGCGGTGCAGAGTTCCGGCAGCAGGACCACTGGAAGCGGCACATGAACCAAATGCACAAGTACAACACCTTGCGCGGCCTCAACTTTCTGCCGGTGGACAAGCTGTATCATCGGTGTCAGGAGTGCAACAAGCGGATTGCGATGCACAGTCGGGAGAATCTGCTGAAGCACAAGTTCACCCACCTGCCGTACAGGTGCACCAAGTGCTACATCTGCAAGCGCGAATACAAATACAGGCAAGATCTAATGGTGCACCTGAGATTGGTGCACTGCGAAGAAGTCGTGGCCATGATGCGAGGAGGCTACAATGCAGCCGGCCGGAAGACCCGTGTCCGGGAGTCTCGCACTGAGCAGTTGCAGAGGGAGGAGGGATTCACTCAGGACCAAGATTTGGACCGCATTGAGGTGCGCAACGAGATACTCGAACCGGACGCAGAGGAGTCCAATGTGTTGGAACATTCAAGGAAGTCGGTAGTCGCCGAAGAGGTGTATCCTGTTGGCAGGAAGAAGAAATCGGAGGAGGAGAACGATGACTTTCAGCTCGCTGCGACACTGTGCGAGGACTACATTCATTTCATTTGTCCGGATTGCGGCGACGAGTGCAAAGACCACAACCAGTGGCGCCGGCACATAGAGTTTGCTCACGACTTCATGAGCCGGCGAGGACTAAACTTCCAGAGCACTGCCGACATGCAGATGCAGTGCATCGAATGTAAACAGATTGTAACCCCGAACACCACCAAAACTCTGCGACTGCACAAGTTTAGTCATCTCCCGCACCCGGAATGGATGAACTGCAAGCTCTGCTACAAGGGATTTTCGGATCACGTCAAGGCGGTGAAGCATCTGCTGCGGGAGCATCACATTGACACTCTAATGCCGGAGCGTCCGGGGAATATCTCAGCGACCATCCATCCAGAGGACGAATTTGGCGGGGAAGGACGAAAAGGAGAGGGAAACGGGGATGCGTTGGACGACGAGTCGCCCTATTTTGCGGATGCGCCCAGACGCGGTGGTCGCATCAGCAGTGACGACATGTTCGAGCCCTTTATAGACTATCTCTGTCCGCAGTGCGGCAAGGAGTTCCGCGAGAAGAAGCACTGGCGCACCCACGTGGTCATGATGCACGGAATGAACGACCTGTCGAAGCTGAACTTCAATGTGATAGACGAACGGAAGCTGAAGTGCCTCGAATGCGACAAGATCATCACCAATGCGTATGGCATCCAGAATGCCCAGCAGCACAGGATCACCCATTTGCCGTTCAAGGCCTATGCCAGATGCACCAAGTGCCACAAGTCGTACACGGACAGGAAGGGTCTGGTGAAGCATCTGGCCACCTATCATCGCATAAGCGACATGCCTCGCAGGTCGGCCGGTGGAGAATCAGGTGGCGGCGGAGAACTTCCGTTGCCCACCGCTCCGAAGCAACCCCGCAAGCAGATCGTCACGGTGGCTAATGAGACTTACGAAATAATCTACCTGGACGACCCGGAGCCAGCCATTGAGGAGGAGAACGATTTTGGGGAGCAGATGCAGGCGGAGGAAGAGGACTATCCCCCAGCACCGATTGCCCCACCGTCGCCACCAATGCTGCCTCCGGTATCAGGAGAGGTTGTCTCTCCAAACGAGGCACAGCGCTTCAAATGCGTCCACTGCGGCGAGGCCTTCGCTTCCCAGGCAGCCGCTAAGCAGCACAGGCTCGATAAGCACTTCAAGATAAGAAAGAGGTTGCGCAGTCACCTGCCGACACAGAACTCGGAATCGTTTGCTCCCCTGCCGACGGTGGAGCAGAACTACATCTTCCTGTGCCCCTCCTGCGGCATGGAGTACAAGACGCAGTTCGAGTGGCGGCGCCACATCAACGACGTCCACAACTTCGACAAGCGCGAGTATCTGAACATGCGGCAGCTGGACAAGTATCGCTACCAGTGCACCCAGTGCAAGGACATTGTTAGCAACTCGAAGCTGAAGGGCCTGCAGGACCACCACTTCCGTCACCTGCCATATCGCTTGTACTTGAAGTGCCTCATCTGCGGTACCTGCTACAATCACAAGCCGAATATAGCGGCGCATCTGCGGGCGCGGCACAACATCTTCGAGAGGGGGGCGCCGGTGATGGTCACCAAGCCGAGCAAGCAGATGAACCACCGCTATCGGGAGGCGGACAGAGAGAAGGCCCGACTTCCATCACCGATTCCGGTACCCGAGTCACCACCCAGCTGTTCGTCCTCCTCCTCGGGGGCTGCCATGAGTCGCACCCTGAAGCCACAGCCCGGGGCGTTGCCCGTTCGACCCGCTGGACTGAACACCCTGGAGGATAGCATCTCGTATCACAATGCTGTGGACTTGGACTTCATAACGTACTTCTGTCCGAAGTGCAACCAGAACTTTGACTCGCACGCCTTTTGGCGCAAACACATCGTGGAGAAGCACAATTTCAATAGTCGCGAGGGTCTGAACTTCCGGCAGCTGGATAACCATCACTACCTCTGTCTGGAGTGCTACAAGCGGGTGACAGTGACCCACACAAAAGGTGCCATCGGGCAGTTGCAATCGCACAAGTTCCGCCACCTGCCCCATCGCTCCTTCAAGTGCTTGACCTGCGGCGGGGAGTTTGTGCGCAAGCAGATGTTCTTCAAGCATCTGAATCGGGACACCAATCGCTGCGACAATCATCCGCAGCGTGAGCTGGACGACGAGGAGCAGGAACACGATCAGGAGCAGGAGGGAGCGTTGGCTGTTCGGTCGATGTACCAGCTGGCGTGTCCCCAGTGCGGCGATGGCTTCACCACGGTGAAGAGAACTGGATGGAAGGAGCACATCAATGTCTACCACAGTCTCACCAAGCTCGACTTGCTGCACATGATCAAGGTGGACGTGGATCGCTATCGCTGCAATGACTGCAATGAGGAGATCCGGACAACTCGGCTGCGCGAGCTGCAGCACCATCGCTTCCAGCACCTCCCCCACCCGGCCTATGTGCGCTGTAAGCTGTGCGACGAGACTGAAGATTGCTCGGAATCGGAAGGGTGCAGGCTGCACAGTCTGCAGGAACTGAAACAGCATATCCTGGACAGCCATAAGGCGGCCAAGGAAAAGGAATCTATGCTCGCCAAGATCCGCGATCACATGCGCAAGGAGGAGCAGGAAGACGTAGTGCCAACTGTGGACGATGACGACAACCAGACTGGTCACGACTCAGGTCCATATATGCCATTGCCCCCGCACTTGTTGGACGACGGGGACGATATGGACTTTGAGGATCAATATCTGCTGGGATAG
Protein Sequence: MEGMDLWTSMFSSDFDEPEDGAEGEAGLEGEDGEQYGNGNGNSDLLDADMGDDDILDGEEEDREEEDYDDDGEGENKRKRSGPDPDDDAIFDFELQPMINLSEQPEQPSSLEDNGASMRGQSLAGSQGRNPNAGYPQRPTTSQINATDENGVPINYELGVVYICPACGAEFRQQDHWKRHMNQMHKYNTLRGLNFLPVDKLYHRCQECNKRIAMHSRENLLKHKFTHLPYRCTKCYICKREYKYRQDLMVHLRLVHCEEVVAMMRGGYNAAGRKTRVRESRTEQLQREEGFTQDQDLDRIEVRNEILEPDAEESNVLEHSRKSVVAEEVYPVGRKKKSEEENDDFQLAATLCEDYIHFICPDCGDECKDHNQWRRHIEFAHDFMSRRGLNFQSTADMQMQCIECKQIVTPNTTKTLRLHKFSHLPHPEWMNCKLCYKGFSDHVKAVKHLLREHHIDTLMPERPGNISATIHPEDEFGGEGRKGEGNGDALDDESPYFADAPRRGGRISSDDMFEPFIDYLCPQCGKEFREKKHWRTHVVMMHGMNDLSKLNFNVIDERKLKCLECDKIITNAYGIQNAQQHRITHLPFKAYARCTKCHKSYTDRKGLVKHLATYHRISDMPRRSAGGESGGGGELPLPTAPKQPRKQIVTVANETYEIIYLDDPEPAIEEENDFGEQMQAEEEDYPPAPIAPPSPPMLPPVSGEVVSPNEAQRFKCVHCGEAFASQAAAKQHRLDKHFKIRKRLRSHLPTQNSESFAPLPTVEQNYIFLCPSCGMEYKTQFEWRRHINDVHNFDKREYLNMRQLDKYRYQCTQCKDIVSNSKLKGLQDHHFRHLPYRLYLKCLICGTCYNHKPNIAAHLRARHNIFERGAPVMVTKPSKQMNHRYREADREKARLPSPIPVPESPPSCSSSSSGAAMSRTLKPQPGALPVRPAGLNTLEDSISYHNAVDLDFITYFCPKCNQNFDSHAFWRKHIVEKHNFNSREGLNFRQLDNHHYLCLECYKRVTVTHTKGAIGQLQSHKFRHLPHRSFKCLTCGGEFVRKQMFFKHLNRDTNRCDNHPQRELDDEEQEHDQEQEGALAVRSMYQLACPQCGDGFTTVKRTGWKEHINVYHSLTKLDLLHMIKVDVDRYRCNDCNEEIRTTRLRELQHHRFQHLPHPAYVRCKLCDETEDCSESEGCRLHSLQELKQHILDSHKAAKEKESMLAKIRDHMRKEEQEDVVPTVDDDDNQTGHDSGPYMPLPPHLLDDGDDMDFEDQYLLG

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00615746;
90% Identity: iTF_00477620; iTF_00550532; iTF_00481829;
80% Identity: -