Dmon002988.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila monieri
Gene Symbol
RREB1
Assembly
GCA_035047585.1
Location
JAWNPJ010000025.1:152977-159347[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 13 0.0052 0.41 11.3 0.6 1 21 235 255 235 257 0.96
2 13 0.0003 0.024 15.2 0.2 1 23 267 289 267 289 0.98
3 13 7.2e-05 0.0057 17.1 7.3 1 23 295 317 295 317 0.98
4 13 1.9 1.5e+02 3.3 3.7 2 19 543 560 543 562 0.97
5 13 0.0075 0.59 10.8 0.1 1 23 708 730 708 730 0.97
6 13 1.1e-05 0.00087 19.7 0.7 1 23 740 762 740 762 0.99
7 13 0.00074 0.059 14.0 2.0 1 23 768 791 768 791 0.97
8 13 0.0026 0.21 12.2 2.0 1 23 1043 1066 1043 1066 0.95
9 13 7.7e-05 0.0061 17.1 0.3 2 23 1431 1452 1430 1452 0.97
10 13 0.13 10 6.9 6.3 1 23 1458 1481 1458 1481 0.97
11 13 1.5 1.2e+02 3.6 2.1 1 23 1602 1625 1602 1625 0.91
12 13 0.0075 0.6 10.8 0.5 3 23 1696 1716 1694 1716 0.96
13 13 0.0057 0.45 11.2 5.7 1 23 1722 1744 1722 1744 0.99

Sequence Information

Coding Sequence
ATGCTGGcagcacagcagcagcacagtaccagcaacaacaccaacacaaCTAACACCACAGAGAACGAGATGGAGCGCCAGAGGCGGGACTCCACCACCTCGGAATCCTCGCTGGAGCACCTGGACCTGGGGCGCACGCCCAAAAAGCTCAGCGCAgtcagcggcggcggcagcggcagtctGGTGCTGCAGCCGACGTCGACGCCACACGATGTCGCGACAGCGACGTCGCGCAAACGTAAGCTGCGCCAGctccaacaccaccaccaggacCTGCTCagcgacgaggacgaggaggaggacgaggcaTCAGCATCGGCTGGGCCCCGCCCCCACGGCCGTCAGAAGCAGCGACGCAACGCCTCTGCCTCGGCCAGCATCGTGCTGgacggcagcggcagcgacgCCAGCTCGCTGCGCAAGAAGTTCCGTTTGAATCGCTCAGCAGCTGCGGTGGCGGCTGTCTCCAGTCTCTCGGAATCGGGATTCGTCGACACCACCGCCCACAGCGGCTACTtgggcaacaacagcagctcGGCGACAGCGACGTCgacggcagcagcaactgcgACGCAATCggcgagcagcagcaacagcagcagcggcagcagcaccgCCGGATCCGGCGGATCATCGCCCCAAGGCGGCCTGTGCCTCTCCAGCGGCGAGTCCGGCATCGGGGCGGGGGACGAGCACATGAAGTACGTGTGCCCCATCTGCGAGGTGGTCAGTGCCACGCCCCACGAGTTCACCAATCACATTCGGTGCCACAACTACGCCAACGGGGACACCGAGAACTTCACCTGCCGCATCTGCTCCAAGGTGCTCTCGTCCGCCTCATCCCTGGACAGACACGTGCTGGTGCACACGGGCGAGCGTCCCTTCAACTGCCGCTACTGCCACCTGACCTTCACCACCAACGGGAACATGCACCGCCACATGCGCACCCACAAGCAGCATCAGGCGaaccagtcccagtcccagtcgcAGTCTCAGtcccatcagcagcagcagcgacgccaGCAACAGTCACATcctgcccagcagcagcaacagctgcagcagcagcagcagcatcagcatctccaacagcaacagagcCTCAATCCCGCCCAGCAGTCGCTGTCGGGACGGGCGGAGAGCTACGAGAGCGACGCCAGCTGCTCCACAGACGCCTCCAGCGGGCACAGCCGCAGTCGCAGCAGCTCCTCCCTcacccacaacaacaacaactcgcAGAAGGCCAACCACAACCACAACCACAAGGACATGGAGCTGGacctggagctggaggaggaggtgaaGCACCACCAGAACCGTCGCGGCCTCAAGACAACCATCAACAACAATGTCATCGAGAGCGAgcacgaggaggaggaggaggaggaccagGATCACGACGATGTCGATGAGGAGGCGGATGTGGCCATGCTGACGTCCACCCCGGATGTCGCCACCCTGTTGGCCGGTGCCAGTGCCTCGGGAGCTGCCTCCCGCTCTGTTTCCCCCTCGTCGGCCGCCTCGCCGGCCCTCCTGCTCAGTTGCCCCGCCTGCGGAGCCGGGGACTTCGAGACGCTGCCATCGTTGTGCGACCACCTGGACGCCCGGCACTCGGACATCCCGGCCAAGTGCCGCGATTGCGAGGTGATCTTCGCCAGCCACCGCCAGTTGCAGGCCCACTGCTGCCGCATCGGACTAGGACGTCCAGCTGGAGTCGgactgccgccgctgctgggCGCCAGCAGCTCCCCGCTCCACGGCGACGACGATGCCGAGGACGAGGATGATGAGGACGCGGAGCGTCGTCTGCGCCTGGAGAAGCAGCGCCTGGCCGACCAGCGCGAGGACTTCTTCCAGCAGCTCTACCTCAAGGGCAAGACCTCCGGCGAGCATCCGCCCTCGCCCATCAAGCACGAGCCGGCGGACAGCAAGGACCTGGCCGACATCCAGAGCATCCTGAACATGACCAGCTCCAGCTGCACCAGCAGCTTCCTGCGCAACTTCGAGCAGTCGGTGAACACGCCCAGCTCCAGCCAGTACAGCCTGGACGGGCGCgaccaggaggaggaggcgcaGGATGCCTTCACCTCGGAGTTCCGGCGGATGAAGTTGCGGGGCGAGTTCCCCTGCAAGCTCTGCACCGCCGTATTCCCCAATCTGCGCGCCCTCAAGGGCCACAATCGCGTCCACCTGGGCTCAGTGGGTCCGGCCGGGCCGTTCCGGTGCAACATGTGCCCCTACGCCGTCTGCGACAAGGCCGCCCTGGTGCGGCACATGCGCACCCACAACGGGGACCGTCCCTACGAGTGCGCCGTCTGCAACTACGCCTTCACCACCAAGGCCAACTGCGAGCGGCACCTGAGGAACCGGCACGGCAAGACCAGCCGGGAGGAGGTGAAGCGCGCCATCATCTACCATCCGGCGGAGGACGCCGGCTGCGGCGAGGACGGCAAGTCCCGTCTCGGCGAGGATCTGGACCTGAGCTTCCGCTCGATCAGCCCGACTCccccgccgccaccgccgccgccgctccCGGAGAGCAGCTCCCAGCTGAAGCACATGCTCCTCGGCGAGAACCAGCCGGCGGGTGGGTCTCTGGTGGACAAGAAGCCCAGCCAGGAGAAAGGCTCGCCCAGCGCCGCCCTGGACTTCAGCATGGACGTGCTGGATCTCAGCAAGAAGCCCTCCGGCGGATCGGCGGCCATTACCCCGACTCCCACACCGAATCCGGCTCCGCTGGTGGCTCCGCCGGGAGTGCCTGGCACCCCGGACTTGGCCGCCGCCCTGGAGCAGCACCAGTTGCTCCTcgcccagcagcagctctTCGCCGGAGCCGCCGGTGATGCCGCCTCCCAGTATGTCCAGCAGTTTTTCCGCAGCCTCATGCTGCAGTCCCAGAGCCCGAGCTTCTCGTACCTCTATGGTGCCTTCATGGCCCCGCCGCCACCGCAGGCCAACCCGGAGAAGCCCCCTCCGCTGGTGAGTCCGCCCACCCGGGGCCTCAATCCTCTGCCGATGGGCGGCGTGGGCGTGCCAGTGCCGCCGGGCGGGCCCGTCAAGATGGTCATCAAGAACGGCGTCCTGATGCCGAAGCAGAAGCAGCGCCGCTACCGCACCGAGCGGCCCTTCGCCTGCGAGCACTGCTCCGCCCGCTTCACCCTCCGCAGCAACATGGAGCGCCACGTGAAGCAGCAGCACCCCCAGTTCTATGCCCAGCGCCAGAGGAGCGGCCACCACGTGATGCGCGGACGTGGCGCCTCCaacgccgctgccgctgccgccgccgccgctgctgccgctggcATGGGAGTTCCCGGCGTGTCATCCGCCGGCGTCGGCTCCGGCGCCCATCACCATCCCGGCCATGGTCATGGACACGGCCATGCCCCCATCTCGGAGCAGGTCAAGTACGCCATTCTCGCCCAGCAGCTGAAGGCCCACAAGAACACGGATCTGCTGCAGCAGGCCCTGGCCCACGGATCGAGCAGTGTGTCCGGCAATCCCCTCCTGCACTTCGGCTATCCACTGGCCACTCCGCCGCCCAGCTCTGCACTGCACAACGGCGGCAGCGGCCAGGCGGGAAACGGGGTTCCCATGGTCTCCATGGACGACGATGAGCCCAAGCTGATCATCGATGAGGACGAGAACGACAACGACGTGGAGGAGGTGGACGACttcgaggaggacgaggaggaggatgaggaggaggatgagccGGAGGACGAGCCCGAGATCATTGCCGATGAGGAGCCACTGCCACGCGACGAGGTGGAGGACCAGCCGCTGGACAAGatggaggagctggagctgccgAAGCCACTCACGGAGCAACTGCCACTCGAGGCGGCCCAGAAGACCGCCGAGACCATCCTGGAGCAGGCCATCAAGGCGGGCAAGCCCGTGACCACGCCCCCGCCTCCGCcgaaggagcagcagctggagCAGATCGCTCCGCCCGCTCCCAGCTCCCTGAAGACGATGATCGCCCAGGCCGAGTCCGTGGCCAAGTCCCTCAAGGAGGTGGCCAGTTCGCCGTTCAAGGACGAGTCGCAGGACCTGGTGCCGGTGGCCAAGCTGGTGGACAACGCCACGAGCCAGAACATGAGCTTCAACAGCTACTTCCGGCCCAGCGACGTGGCCAACCACATGGAGCAGAGCGACGAGGAGGGCCTTGTGGCCTCCGGCAGCGCCTCCGAGAGCAACAACAGCGGCACCGAGGACGTCACCAGCAGCTCCTCCAACAGCGAGCCGAAGAAGAAGTCCGCCTACAGCCTCGCCCCCAACAGGGTCTCCTGCCCCTACTGCCAGCGCATGTTCCCGTGGAGCAGCTCCCTGCGCCGCCACATCCTCACCCACACCGGCCAGAAGCCCTTCAAGTGCTCCCACTGCCCCCTGCTCTTCACCACCAAGAGCAACTGCGACCGCCACCTGCTGCGCAAGCACGGCAACGTCGAGTCCGCCATGTCCGTCTACGTGCCCACCGAGGACGTCAGCGAGCCGATTCCCGTGCCCAAGTCCGTCGAGGAGAtcgagctggaggagcagcgCCGCCGCCAGGAGGCGGAGCGCGAGCGGGAACGCGAACGGGAGCGTGCCCGGGAGCGGGAGATGGAGCGGGAGCGcgaactggagctggagcgcGAGCGGGAGCTGGccgagaaggagaaggagcgcGAACGCCAGCAGCTCATCCAGAAGTTGGCTGCCCAGatggccgccgccgccgtggCTGCAGCTGGCCCCGGTGCTGCGGGAGTCGTCCCGCCCGGCGGATTAGACGCCCAGGCTGGCGGGGATCTGCCCTACAAGTGTCATCTCTGCGAGGGCTCCTTCGCCGACCGGCTGCAGTGCCTCGAGCACATCAAGCAGGCCCATGCCCACGAGTTCGCCCTGCTGCTCGCCAAGGGCGCCATCGAGAACGAGTCCGTGCTGGGCGAGTCGGCCTCGGGGAATCCCAGCCAGCCcccaccagccagccagcagcagccccaCTCCGACGATGAGGCCGCCAACGGCGTGGTCGGTGGTGCCGGAGGGgccggggggcgtggcaagtaCCCGGACTACAGCAACCGGAAGGTGATCTGCGCCTTCTGCGTGCGCCGCTTCTGGTCTACCGAGGATCTGCGCCGCCACATGCGCACCCACTCCGGGGAGCGGCCGTTCCAGTGCGAGACCTGCCTCCGGAAGTTCACCCTCAAGCACAGCATGCTCCGTCACATGAAGAAGCACAGCGGACGCGCCCACAACGGCGACGCTCCCGGCTCCGACTGCTCCGATGATGAGCAGGTGAGCAGCAGCCCTCCTGGCACTCCGGCTCCGCCTACGGCCTCCtccgccaacaacaacaacagctgccacaccaacaacaacaacaacaacacggTGAGCGCCAAACTGGGCCTGCCGAAGCTGCACGAGCTGCTGGAGTGGCGGGCCAGCCGGCTGGCGGGGGAGCACAAGGAGAACCTGGGCGAGGCCACGGCCCCCTCGGGCTCCAGCACGGATCTGATCGGGAATCTGCTCGGGATCAGCGACCAGGGCATTCTCAACAAGCTGCTCTCCTCAGCCGACGAGGCGGCCAAGCTCCTCGGCGTGGACAACAAATAG
Protein Sequence
MLAAQQQHSTSNNTNTTNTTENEMERQRRDSTTSESSLEHLDLGRTPKKLSAVSGGGSGSLVLQPTSTPHDVATATSRKRKLRQLQHHHQDLLSDEDEEEDEASASAGPRPHGRQKQRRNASASASIVLDGSGSDASSLRKKFRLNRSAAAVAAVSSLSESGFVDTTAHSGYLGNNSSSATATSTAAATATQSASSSNSSSGSSTAGSGGSSPQGGLCLSSGESGIGAGDEHMKYVCPICEVVSATPHEFTNHIRCHNYANGDTENFTCRICSKVLSSASSLDRHVLVHTGERPFNCRYCHLTFTTNGNMHRHMRTHKQHQANQSQSQSQSQSHQQQQRRQQQSHPAQQQQQLQQQQQHQHLQQQQSLNPAQQSLSGRAESYESDASCSTDASSGHSRSRSSSSLTHNNNNSQKANHNHNHKDMELDLELEEEVKHHQNRRGLKTTINNNVIESEHEEEEEEDQDHDDVDEEADVAMLTSTPDVATLLAGASASGAASRSVSPSSAASPALLLSCPACGAGDFETLPSLCDHLDARHSDIPAKCRDCEVIFASHRQLQAHCCRIGLGRPAGVGLPPLLGASSSPLHGDDDAEDEDDEDAERRLRLEKQRLADQREDFFQQLYLKGKTSGEHPPSPIKHEPADSKDLADIQSILNMTSSSCTSSFLRNFEQSVNTPSSSQYSLDGRDQEEEAQDAFTSEFRRMKLRGEFPCKLCTAVFPNLRALKGHNRVHLGSVGPAGPFRCNMCPYAVCDKAALVRHMRTHNGDRPYECAVCNYAFTTKANCERHLRNRHGKTSREEVKRAIIYHPAEDAGCGEDGKSRLGEDLDLSFRSISPTPPPPPPPPLPESSSQLKHMLLGENQPAGGSLVDKKPSQEKGSPSAALDFSMDVLDLSKKPSGGSAAITPTPTPNPAPLVAPPGVPGTPDLAAALEQHQLLLAQQQLFAGAAGDAASQYVQQFFRSLMLQSQSPSFSYLYGAFMAPPPPQANPEKPPPLVSPPTRGLNPLPMGGVGVPVPPGGPVKMVIKNGVLMPKQKQRRYRTERPFACEHCSARFTLRSNMERHVKQQHPQFYAQRQRSGHHVMRGRGASNAAAAAAAAAAAAGMGVPGVSSAGVGSGAHHHPGHGHGHGHAPISEQVKYAILAQQLKAHKNTDLLQQALAHGSSSVSGNPLLHFGYPLATPPPSSALHNGGSGQAGNGVPMVSMDDDEPKLIIDEDENDNDVEEVDDFEEDEEEDEEEDEPEDEPEIIADEEPLPRDEVEDQPLDKMEELELPKPLTEQLPLEAAQKTAETILEQAIKAGKPVTTPPPPPKEQQLEQIAPPAPSSLKTMIAQAESVAKSLKEVASSPFKDESQDLVPVAKLVDNATSQNMSFNSYFRPSDVANHMEQSDEEGLVASGSASESNNSGTEDVTSSSSNSEPKKKSAYSLAPNRVSCPYCQRMFPWSSSLRRHILTHTGQKPFKCSHCPLLFTTKSNCDRHLLRKHGNVESAMSVYVPTEDVSEPIPVPKSVEEIELEEQRRRQEAERERERERERAREREMERERELELERERELAEKEKERERQQLIQKLAAQMAAAAVAAAGPGAAGVVPPGGLDAQAGGDLPYKCHLCEGSFADRLQCLEHIKQAHAHEFALLLAKGAIENESVLGESASGNPSQPPPASQQQPHSDDEAANGVVGGAGGAGGRGKYPDYSNRKVICAFCVRRFWSTEDLRRHMRTHSGERPFQCETCLRKFTLKHSMLRHMKKHSGRAHNGDAPGSDCSDDEQVSSSPPGTPAPPTASSANNNNSCHTNNNNNNTVSAKLGLPKLHELLEWRASRLAGEHKENLGEATAPSGSSTDLIGNLLGISDQGILNKLLSSADEAAKLLGVDNK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00504177;
90% Identity
iTF_00481716;
80% Identity
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