Basic Information

Insect: Drosophila mojavensis
Gene Symbol: -
Assembly: GCA_018153725.1
Location: JAECYD010000229.1:923034-926938[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.00038 0.029 14.8 0.1 1 23 161 184 161 184 0.96

2 14 0.00019 0.015 15.8 2.3 2 23 233 255 232 255 0.97

3 14 0.011 0.89 10.2 0.9 1 23 357 380 357 380 0.93

4 14 0.24 18 6.0 4.1 2 23 429 451 428 451 0.96

5 14 0.003 0.23 12.0 0.5 1 23 516 539 516 539 0.88

6 14 6.9 5.4e+02 1.4 0.0 2 13 558 569 557 574 0.81

7 14 0.00063 0.049 14.1 3.3 2 23 590 612 590 612 0.96

8 14 0.0021 0.16 12.5 0.1 1 23 715 738 715 738 0.95

9 14 7.7e-05 0.006 17.0 0.3 1 23 790 813 790 813 0.93

10 14 0.0011 0.083 13.4 2.2 2 23 863 885 862 885 0.97

11 14 0.0026 0.2 12.2 1.5 1 23 973 996 973 996 0.91

12 14 0.13 9.8 6.9 1.5 1 21 1048 1068 1048 1069 0.95

13 14 0.22 17 6.1 0.2 2 23 1112 1135 1111 1136 0.87

14 14 6.6 5.1e+02 1.5 0.4 1 9 1154 1162 1154 1178 0.68

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.00038	0.029	14.8	0.1	1	23	161	184	161	184	0.96
2	14	0.00019	0.015	15.8	2.3	2	23	233	255	232	255	0.97
3	14	0.011	0.89	10.2	0.9	1	23	357	380	357	380	0.93
4	14	0.24	18	6.0	4.1	2	23	429	451	428	451	0.96
5	14	0.003	0.23	12.0	0.5	1	23	516	539	516	539	0.88
6	14	6.9	5.4e+02	1.4	0.0	2	13	558	569	557	574	0.81
7	14	0.00063	0.049	14.1	3.3	2	23	590	612	590	612	0.96
8	14	0.0021	0.16	12.5	0.1	1	23	715	738	715	738	0.95
9	14	7.7e-05	0.006	17.0	0.3	1	23	790	813	790	813	0.93
10	14	0.0011	0.083	13.4	2.2	2	23	863	885	862	885	0.97
11	14	0.0026	0.2	12.2	1.5	1	23	973	996	973	996	0.91
12	14	0.13	9.8	6.9	1.5	1	21	1048	1068	1048	1069	0.95
13	14	0.22	17	6.1	0.2	2	23	1112	1135	1111	1136	0.87
14	14	6.6	5.1e+02	1.5	0.4	1	9	1154	1162	1154	1178	0.68

Sequence Information

Coding Sequence: ATGGAAGGTATGGATCTGTGGACGTCAATGTTTTCAGCAGATTTTGACGAAGGCGGTGGTGAGATGGAGGGCCATAATAATGGCGATAACGCGCTGGCAGACGAGTTTATGGGAGAAGAGGACGAGGAAGAACAGGAGGCTGAAGAGGATGAGGGCTCGGCCGACGAAAGGGGCAGCAAACAAAAAGGACACGAGCCCGATGACGATGCCATATTTGATTTTGAGCTAGAGCCTATTGTTAACATTGCGGAACCAGAACTGGAACCGTTGCCCAGACAAACGGCTGTCTCCCTGCAACCCCCAATGCCAACGGGTCCGGCCATCCGACCCCAGCACCGCCAGTCGTTGCCAGCGTCGTTTAGCTCTCAGCCTATGATGGCTCGTGGCGGTGCAGGTACACCGTCCACACGGCCAACAACCTCACAGATCAATGCCACCGATGAGAACGGCGTGCCCATCAATTATGAACTCGGCGTTACTTATATATGCCCCGCCTGTGGCGCAGAGTATAGGCAGCAGGACATGTGGAAGCGTCATATGAACCAGATGCATCAGTACAATACCCGACGAGGTCTCAATTTCGTGGCCATTGACAAGTTGTATCACCGCTGCTTGGAGTGCAACAAGCGCATCGCGATGCACAGCAGAGAGAATTTGCTAAAGCACAAGTTCACACATTTGCCATTTAGGTGCACCAAGTGCCACATATGCAAGCGCGAGTACAAATACAGGCAGGACCTGATGGTACATCTTCGAATGGTGCACTGTGATGAAGTGGTGGCCATGATGCGTGGTGGCAAACTGAGTGCCGGACGCAAGACGCGTGTTCGTGAGCCGCGCATCGAGCAGCACCGCGAACATTACGGACAGGCTCATGACGACGACGGCATTGAGGTGAAAAACGAGGTGTTGGAAACAGAAGGCAGCGCGAAGGCAGCTCAAGAGTCCCATCATGATTTCGATGATGAGTACAGTCACAGTTCCAACCAAGCGGCTGTAAAGAAGCGTACCACTTCTGTGGGAGCCAATGGCAGTGGTGCAGCGGATATTTGCGAGGACTATATACACTATATGTGTCCGGATTGTGGCACCGATTGTGATACGCACGCCCAGTGGAGTCAGCACATTGAGTTTGTACACGATTACGTCAGTCGAAGGGGGCTGAACTTTCGCTGCGTGGATATGCAAATGCAGTGCCTCGAGTGCAAGCAGTTTGTTATCCCGAACACCATTAAGACACTGCGCACACACAAGTTCAGCCACTTGCCACAACCGGAGTGGATGCGTTGCAAGCTGTGCTATAAGGGTTTTACAGAGCATCATGAAGTTATGACGCATCTTCTTAAACAGCATAATTTGGAAACCTTAATGCCTGAGAACGAGGAGGAGGAGCAACAGCAGCCATTGGCTATATCCAGTGTGGGTGATGAGTGTGAGGAGAATCCTGGCATTGGTTGCGATGATGAGACTTCATTGCATTGGGACGATGTGCCTCGTCGTGGTGGTCGTATCGGTAGCGATGATATGTACGAACCTCATATTGATTATCTTTGTCCGCAGTGCGGCAGAGAGTTTATAGAGAAGAAGCATTGGCGCACCCATGTTGTACAAGTGCATGGCATGAATGATCTGACCAAGTTGAATTTCGAGGTGATCAACGATCGCCAATTGAAGTGTACCGAATGCGAGAAGATCATAACAAATGCCTATGGCATACAGAATGCCCAGCAGCACAGAATAACACATTTGCCCTACAAGGCGTACGCGCGATGCCGCAAATGCCATAAGTCCTACACGGACAGAAAGGGTCTTGTCAAACACTTGGCAACATACCATCGTGTGGGCTACGAGCCGCGCAAAGTGGTTGGATCAGGAGCAGGTGTTGCACCATTAACGCCAAACAAATCACACACGCCGCGCAAGCAAATCGTCACCGTGGCCAATGAGACATATGAGATTATATATTTGGATGAGGAGCAATCACCGCCTAGTAACAACAATATAAATGATGAGAATGATTTCGGCGAGCAAATGCAAGCGGACGACGATGACTACGCTCTAGGCAGCACCAGTGGCTTAATGGGTCGCCAGCCACAAGCACCGACTGCTGTCGCTCCTGCACCAATTCCTAATCCGAATCGTTATAAATGCGTAGACTGTGGCTCGCTATTTGCCACACAGATCGCATTAAAGACGCACATCAGCGAGGAACATGATTTTATGGACACGCAATACAGTGCCAAAAAGTTTGACAATGCGGAGCCCACGGAGGAGGCTGCTGCAGTGCCGGTTGCCGTTTCAACCACTGCAGCTAGTTTGCCTGTAAAGAACACCTCGGGAGCTTCCACCATAGAGCAGAATTATATATTCCTGTGCCCGTCGTGCGGCAAGGCCTACAAGACTCAGTTCGAGTGGCGTCGCCACATCAACGAAGAGCACAACTTCGACAAACGGCAGTATTTAAATATGCGCCAGCTGGACAAATATCGCTATCAGTGCACCCTTTGTAAGGATGTTGTGTGCAATTCTAAGCTGAAAGGCTTGCAGGATCATCATTTTCGTCATTTGCCTTATCGGCTGTATCTGAAGTGCCTGGTGTGTGGCACCTGCTACAATCACAAGCCCAACATCGCAGCGCATCTGCGCACGCGGCACAACATCTATGAACGGGAGCCCTCATCTTGGCGTGATCAGCACCAAAAGTCCCAGAATGGCCACGAGCAGCACAAGCATAAAGATAAGGATGGGGATACGCAAGCAACTGCTGCCACCTGCTCAGCTTCTGCCTCACCTACTCCCAGTAGCAGTCGCACGCTCAAGCCACAGCCGGGCGTGTTGCCGACGAGACCTGCTGGACTCAACACATTGGAGGATAGTATATCGTATCACAATGCCGTGGATCTGGACTTCATCACCTATTTTTGTCCCAAGTGCAATAAGAACTTTGACTCGCACGCCTTTTGGCGCAAGCACATCGTTGAGGTACACAACTACAATAGTCGGCTAGGCTTGAATTTTCGCCAGATTGACATTCATCACTATCTGTGCCTGGAGTGCTATAAGCGTGTGACAGTGACGCACACTAAGGGCGCCATTGGGCAGCTACAGTCGCACAAGTTCCGACATCTGCCTTATCGCTCCTTCAAGTGCTTGACCTGCTCCGGGGAGTTTGTTCGCAAGCAAATGTTCTTCAAGCACTTGAACCGCGACACTAATCGTTGCGACAACAAGCCATTGACTGGCCAGGAGAATGATGAAGATACAACGGATCAGTCAGACAGGCCGCCTCCCATGCTCGCAAAAGAGACACTCGATGTCGCGACATATCGCTTGATGTGTCCTCAATGCGGTGATGGGTTCACCACTAGCAGCAAAGCTCTGTGGCGAGAGCACATTAACATCCATCATGGTCTAGGCAAGCGGGAGATGCTGCACATGCGCAAGCTGGGCGACGAATTGTATCGCTGCACGGACTGTGAAGAGCAGTTGCAAACGAAGCAGCTGAGAGTGCTGCAGCAGCATCGCTTCCAGCATTTGCCCTATGCCGCATATATACGCTGCCAGCTATGCGAACAGCAGTTGCCGGATGGGGTAAGTCATGGTGTGGCGGCTGCCGGATTACACAGTATGCGTGAACTGCAACAGCACATACGCGACGTACATCCGGATGTGGTGGCGCAGGACAAGCAAATGCAAGTGCTATTGGACGAGGAGGAAGATAGTCAGCAGCTGGCTGTTGGCGGAGAAGCAACTGATAGCGGACTCTATATGCCGCTGCCGCCGCATTTGCTAGACGATGCTGCAGAGGATATGGAGTTTGAGGAACAGTATCTGCTAGGTTAA
Protein Sequence: MEGMDLWTSMFSADFDEGGGEMEGHNNGDNALADEFMGEEDEEEQEAEEDEGSADERGSKQKGHEPDDDAIFDFELEPIVNIAEPELEPLPRQTAVSLQPPMPTGPAIRPQHRQSLPASFSSQPMMARGGAGTPSTRPTTSQINATDENGVPINYELGVTYICPACGAEYRQQDMWKRHMNQMHQYNTRRGLNFVAIDKLYHRCLECNKRIAMHSRENLLKHKFTHLPFRCTKCHICKREYKYRQDLMVHLRMVHCDEVVAMMRGGKLSAGRKTRVREPRIEQHREHYGQAHDDDGIEVKNEVLETEGSAKAAQESHHDFDDEYSHSSNQAAVKKRTTSVGANGSGAADICEDYIHYMCPDCGTDCDTHAQWSQHIEFVHDYVSRRGLNFRCVDMQMQCLECKQFVIPNTIKTLRTHKFSHLPQPEWMRCKLCYKGFTEHHEVMTHLLKQHNLETLMPENEEEEQQQPLAISSVGDECEENPGIGCDDETSLHWDDVPRRGGRIGSDDMYEPHIDYLCPQCGREFIEKKHWRTHVVQVHGMNDLTKLNFEVINDRQLKCTECEKIITNAYGIQNAQQHRITHLPYKAYARCRKCHKSYTDRKGLVKHLATYHRVGYEPRKVVGSGAGVAPLTPNKSHTPRKQIVTVANETYEIIYLDEEQSPPSNNNINDENDFGEQMQADDDDYALGSTSGLMGRQPQAPTAVAPAPIPNPNRYKCVDCGSLFATQIALKTHISEEHDFMDTQYSAKKFDNAEPTEEAAAVPVAVSTTAASLPVKNTSGASTIEQNYIFLCPSCGKAYKTQFEWRRHINEEHNFDKRQYLNMRQLDKYRYQCTLCKDVVCNSKLKGLQDHHFRHLPYRLYLKCLVCGTCYNHKPNIAAHLRTRHNIYEREPSSWRDQHQKSQNGHEQHKHKDKDGDTQATAATCSASASPTPSSSRTLKPQPGVLPTRPAGLNTLEDSISYHNAVDLDFITYFCPKCNKNFDSHAFWRKHIVEVHNYNSRLGLNFRQIDIHHYLCLECYKRVTVTHTKGAIGQLQSHKFRHLPYRSFKCLTCSGEFVRKQMFFKHLNRDTNRCDNKPLTGQENDEDTTDQSDRPPPMLAKETLDVATYRLMCPQCGDGFTTSSKALWREHINIHHGLGKREMLHMRKLGDELYRCTDCEEQLQTKQLRVLQQHRFQHLPYAAYIRCQLCEQQLPDGVSHGVAAAGLHSMRELQQHIRDVHPDVVAQDKQMQVLLDEEEDSQQLAVGGEATDSGLYMPLPPHLLDDAAEDMEFEEQYLLG

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00532646;
90% Identity: iTF_00551845;
80% Identity: -