Basic Information

Insect: Drosophila mimica
Gene Symbol: RREB1_1
Assembly: GCA_037043585.1
Location: JBAMBE010000576.1:3354241-3360962[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 13 0.036 2.4 8.8 0.8 1 21 264 284 264 286 0.93

2 13 0.00034 0.022 15.1 0.2 1 23 296 318 296 318 0.98

3 13 0.00025 0.016 15.5 7.2 1 23 324 346 324 346 0.98

4 13 0.24 16 6.2 1.7 2 20 581 599 581 601 0.93

5 13 0.016 1 9.9 0.2 1 23 744 766 744 766 0.97

6 13 1.3e-05 0.00081 19.7 0.7 1 23 776 798 776 798 0.99

7 13 0.00084 0.055 13.9 2.0 1 23 804 827 804 827 0.97

8 13 0.003 0.2 12.2 2.0 1 23 1073 1096 1073 1096 0.95

9 13 8.8e-05 0.0057 17.0 0.3 2 23 1483 1504 1482 1504 0.97

10 13 0.15 9.5 6.8 6.3 1 23 1510 1533 1510 1533 0.97

11 13 9.5 6.2e+02 1.2 3.4 1 23 1654 1677 1654 1677 0.78

12 13 0.0086 0.56 10.7 0.5 3 23 1737 1757 1735 1757 0.96

13 13 0.0014 0.088 13.3 4.8 1 23 1763 1785 1763 1785 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	13	0.036	2.4	8.8	0.8	1	21	264	284	264	286	0.93
2	13	0.00034	0.022	15.1	0.2	1	23	296	318	296	318	0.98
3	13	0.00025	0.016	15.5	7.2	1	23	324	346	324	346	0.98
4	13	0.24	16	6.2	1.7	2	20	581	599	581	601	0.93
5	13	0.016	1	9.9	0.2	1	23	744	766	744	766	0.97
6	13	1.3e-05	0.00081	19.7	0.7	1	23	776	798	776	798	0.99
7	13	0.00084	0.055	13.9	2.0	1	23	804	827	804	827	0.97
8	13	0.003	0.2	12.2	2.0	1	23	1073	1096	1073	1096	0.95
9	13	8.8e-05	0.0057	17.0	0.3	2	23	1483	1504	1482	1504	0.97
10	13	0.15	9.5	6.8	6.3	1	23	1510	1533	1510	1533	0.97
11	13	9.5	6.2e+02	1.2	3.4	1	23	1654	1677	1654	1677	0.78
12	13	0.0086	0.56	10.7	0.5	3	23	1737	1757	1735	1757	0.96
13	13	0.0014	0.088	13.3	4.8	1	23	1763	1785	1763	1785	0.99

Sequence Information

Coding Sequence: ATGCTcgccacacagcagcagcaacagcagcaacaacaacagcaacagtcgcacacagtagcagcaactgcagcagcagcagcaacacatgAGGATGCTCGGGACTTGGGGTTAATGGAGACGCGACAGCGTCGCGATTCGAGCACCTCAGAATCCTCGCTGGAGCATTTGGATTTGGGTCGTACGCCCAAAaagttgagcagcagcagcggcgcacCGCAGCCGACGTCGACGCCGCACGACGCAGCAGTGACAGCGACGTCGCGCAAGCGGAAACTGcgacagcaacaccagcagcagcagcaacagttgccgctCTCCGatgaggagcaacagcagcagcagctgttggatTCGTCAGCGCAGCGACCGCGTCACAAGCAGCGAGTCAGCgccgttgctgccgctgccagcgCCAGCATCGTTGTTGACTACAGCGCCAGCGGCGACGCCAGCTCGCTGCGCAAAAAGTTTCGACTGAAtcgcagcagcgccagcagcaataCCGCTAACGGTGATTTATCCGAGTCTGGCTTCGTTGATGGCAGCGCCCTCAGTGGCTATCtgcttggcaacaacaacaacaacaacaataacaacaacaataacaacaacaacaataacaacaacaatatcagtagtagcagtagcagcagcgcagttgctcagtcagcaacagcagcgtcgGCAGCGCAGCATGCGTCAAGCGTTAGCAGCTCGGGCGGCTCCTCGCCACAGGGCCTCTCGAGCGCCGAGTCGGGCATCGGTGCCGGTGATGAGCACATGAAATATTTGTGCCCCATCTGCGAGGTCGTCTCGGCCACGCCCCACGAATTCACCAATCACATTCGCTGCCACAACTACGCCAACGGCGACACCGAGAACTTCACCTGCCGCATCTGCTCCAAGGTGCTCTCGTCGGCATCCTCGCTGGACCGACATGTCCTGGTGCACACCGGAGAGCGTCCGTTCAACTGTCGCTATTGCCACTTGAACTTCACAACCAACGGGAACATGCACCGACACATGCGCACCCACAAGCAACACCAGGcctcgcagcagcagcaacagcagcagcactcgcaacagcagcaatcaaaCCAAtcaaaccagcagcagccggcacagtcgcagtcgcagcaacaacaacagcgacgccAGCAACATGCAAGTGGAGCCGGAGCAACTGGCTCCGGATCGGGATCCGCACAGTTGCTGACGACGCGAGCGGAGAGCTATGAAAGTGATGCCAGCTGCTCGACGGATGTGTCCAGTGAGCTGAACagtcacagcagcaacagcaatcaatccaaccacaacaacaacaacaacaatagccacaaaacgaacaacaacaacaacaacaatagcaacaacaacaacaacaacaatgaggaTGAACTAGAGCTGGAGGATGAGCAGCTAGTGCtgagcagcaagcagcgaCGCATCAAAGCagcccaaaacaacaacaatataattaGGGATGAGGAGCACGAGAATCGGCCGGATGATGATTCGGATGTGGACAGCGTTGATAGCGTGGCCCAGGTGATAACAAGCACACCGGATGTGGCCACGTTGCTAGCCTCGGGCGGCACTTCGCCCACCCACTCGCATTCGGATTCGCATTCGCCGCCTTTGCTCCTGCAGAGCTGCCCCGCCTGCAATTCGGGTGAATTTGAATCAGTGCCAGCGCTGTGCGCCCATCTGGATGCCGAGCATGCGGACATACCGGCCAAGTGTCGGGAGTGTGAGGTGATCTTTGCCACACATCGACAGCTGCAGGCGCACAGCTGTCGAGGATTGCCGCCGCTCCTTGGTTCGAGCTCATCGCCACTGCACAAGCAGGAGGAGAGCGAactggaggagcagcagcagcacgaggAGAACCACGaacagcagcacaagcaggaggaacaggagcaggctGAGCAGCGAGAATGTGAAGATTTCTTCCAACAGCTGTATCTGAAGAACAAATCGTCAACAACGCTACTCCCCTCTCCGATCAAACAtgagccggcggatcagcgacaGGATCTGGCCGATATCCAAAGCATACTCAATATGACCAGTTCCAGCTGCACCTCGAGTTTCCTGCGCAATTTCGAGCAGTCGGTGAACACGCCCTGCTCCAGCCAATACAGCGTCGATGGACGCGATGGCGAGGAGGAGGCCCAGGACGCCTTCACCAACGAATTCCGGCGAATGAAATTGCGCGGTGAGTTCCCCTGCAAGCTGTGCACAGCCGTCTTTCCCAATCTGCGGGCACTCAAAGGCCACAATCGCTACCATCTGTCGGAGGTGGGCGCAGCGGGTCCGTTCCGTTGCAACATGTGTCCCTACGCCGTTTGCGACAAGGCGGCGCTCGTGCGGCATATGCGCACCCACAACGGTGATCGGCCGTACGAGTGCGCCGTTTGCAACTATGCCTTCACCACAAAGGCGAACTGTGAGCGCCATTTGCGCAATCGACATGGGAAGACCAGTCGCGAGGATGTGAAACGTGCGATTGTCTATCATCCGGCCGAGGATGCCAGCTGCGAGGAGAACAAATCCCGCACCGATGCCGATATGCTAACGGAGCTGAGCGGCTATCGCTGTGCCACACCCACGGAGCACAGCTCCTCGGCCAGCTCCTCGTCCCAGCTGAAGCACATGTTGCTGGCGGAGCCGACGCCGGCCGtaaaagtagcagcagcagcagcaacaacatcgctGCCGCAACAACCGCTCAAGATTCAGGTGAAGAGCTTGGATCAGCTGGTGGATAAGCCACTGCCTGCACTCGATCTCAGCATGGATGCGCTCGATCTGAGCAAGAAGCCCTCACAGCTGCTGGCCGAGCAAAGGGAGCACAGGGAGCAGCTCGAAAGACAtgaattgctgctgcaacaacaacagcagcagcaacaacaacaacagcagcagcagcaacaacagcagcagcagcaacaaatgtttgGGGCAGGCGATGCAGCTGCTCAGTATATGCAACAGCTGTTGCGCAGCTTCATGCTCCAGCAGTCACCCGGTTTTCCTTTCTTTGGcacagcagcggcagcagccggcgcagcaacagcagcaacaattgctgcaatGCCACTGTCGCTGCCGGTGCCACTGCCCGCTGGTGGTCCCGTCAAGATGGTCATCAAGAATGGCGTCCTAATGCCtaagcagaagcagcgacgCTACCGCACCGAGCGTCCCTTTGCCTGCGAGCATTGCTCGGCCCGCTTCACGCTGCGCTCCAACATGGAGCGGCATgtgaagcagcagcatccacagtTTTATGCGCTGCGCCAGCGACACCGGAGCGGTCATCATGTGATGCGTGAACGGGCTGCATCCTCGAGTGCTGTCCAAGCGGCAGCCGCTGCtcaggcggcagcagcggcagctgccgcCGCAGCAATGAGTAATctcagccagcagcaacagttgcagcagcagcagcaacaattgcagcattcacattcgcatcaCGTTCATGCCCCAATTTCGGAGCAGgtgaaatatgcaattttggCGCAGCAATTGAAGGCGCGCAAGGATACGGATTTGTTGCAACAGGCACTGGCACATGGCTCCAGCAGTGTTGTCACCAATCCGCTGTTGCATTttaactacaacagcaacaacaacaacagcagcagcaagcagcagcaacaacagttgagCAACAACACTGGCAACTCTTTGGTGCTGGACGATGATGAGCCGCCCAAGCTGATTATTGACGAGGATGACGAGGATGTGGAGGGTgaggacgatgaggatgaggaggaggagcaggaatTTGATGTCGATGAGGAGGAGCAAGAGGATGAAGAGATGGACTTGGACGatgagcatcagcagcagccgcacgaggacgatgatgatattgacaatgatgatgatgacgatgatgatgcagcagcagcagcagaggcgtcgcagcaacaattgcagccaaCAAAGGACAAACTGCAATCCAAGCCAATTCAGGCGGCCAAAAAGGTAGCGGAAACCATTTTGGAGCAGGCAAACAAAGAGCGCGAGGAGAAAGCATCCGAGAAGCCGCCGCAATCTGAGTCGAAAAGCGGCAACAAACCGGcgacgccaacaacaatgaaaacaatgaTTGCACAAGCGGAATCGGTGGCCAAGTCCTTGAAGGAGGTGGCCAGTTCACCGTTCAAAGATGAATCTCAGGATTTGGTGCCGGTGGCCAAACTGGTGGACAATGCCACCAGCAATCAGGTGTCGTTCAACAGCTATTTCCGTCCCAGCGACGTCGCCAATCACATGGAGCAGAGCGACGAGGAGGGCCTCGTCGCCAGCGGCAGCGCCAGCGAGAGCAACAATTCCGGCACCGAGGAtgtgaccagcagcagcagcagctgcggcaacGATACCAAAAAGAAATCCGCCTACAGCCTGGCACCGAATCGTGTCAGCTGCCCGTATTGCCAGCGCATGTTCCCCTGGAGCAGCTCGCTGCGTCGCCACATCCTGACGCACACCGGCCAGAAGCCGTTCAAGTGCTCCCACTGCCCGCTGCTGTTCACCACGAAGAGCAACTGCGATCGCCATCTGTTGCGCAAGCATGGCAACGTTGAGTCCGCCATGTCCGTCTATGTGCCCACCGAGGATGTCAGCGAACCGATTCCCGTGCCCAAGTCCGTCGAGGAGATTGAGCTCGAGGAGCAGCGACGTCGCCAGGCCGCTGAAGCCGAACAGGCCGAGCGGGAGCAGCGCGAGCGCCAAAAGGAGCGCGAACGCGAACTGGAATTGGAACGGGAACGAGAGCgggaacagcaacagttgatACAACAGTTGCGCCAACAAATGGCcgctgcggcagcagctgctgttgccgttgccgttgtcgcTGCACCAACGCatccaccaccaacaccacagCCAGCCCAATCGCCACCGGGCCTGGAGGCGAGCAGTGATCTGCCCTACAAATGTCATCTGTGCGAATTCTCGTTTGGCGAGCGGCTCCAATGTCTCGAGCACATCAAGCAGCTGCACGCTCACGAGTTCGCGCTGCTCCTGGCCAAGGGGGCGATCGAAACGGATGCACAACtccaacatcaacagcagcaacagttgccagttgctggtggtgctgcgcATTCGGATGATGAGGCTGCCGCTGTCGGCACCAGATCGGGCAAATATCCCGACTATAGCAATCGTAAAGTGATTTGCGCATTTTGCGTGCGTCGCTTCTGGTCGACGGAGGATCTGCGGCGACACATGCGCACCCATTCCGGTGAGCGTCCGTTCCAGTGCGAGATCTGCTTGAGGAAGTTCACATTGAAGCACAGCATGCTGCGCCACATGAAGAAGCACAGTGGACGCAGTCACAATGGTGGCGAGCTCGATCATCAATCCGATTGCTCCGATGATGAGCAACTGTTGCCCTGCTCCCCACCCTCAACGCCAACGcccactaacaacaacaacaacaacaacacttgccagaacaacaacaacaataacaacaacaacaacaataatagcaatagcaaGCAGGTGCTGCGCGAGCTGCTGGGCAAGGCGAACGAGTGGCGAGTGAGTCGCCTGGGTGAGCACAAGGAGAACATTGccgaggcaacaacaacaccgacatcagcaacagcagcagcggcagcaacagctgcagcagcagcagcagcagcggcggcagcagcagctgttgccagtGGCGATCTAATTGGTAATCTGTTGGGGATCAGTGATCAGGGCATACTAAACAAGCTGCTCTCCTCACCAGACGAGGCTGCAAAGCTGCTTGGAGTGGAGAAGTAA
Protein Sequence: MLATQQQQQQQQQQQQSHTVAATAAAAATHEDARDLGLMETRQRRDSSTSESSLEHLDLGRTPKKLSSSSGAPQPTSTPHDAAVTATSRKRKLRQQHQQQQQQLPLSDEEQQQQQLLDSSAQRPRHKQRVSAVAAAASASIVVDYSASGDASSLRKKFRLNRSSASSNTANGDLSESGFVDGSALSGYLLGNNNNNNNNNNNNNNNNNNNNISSSSSSSAVAQSATAASAAQHASSVSSSGGSSPQGLSSAESGIGAGDEHMKYLCPICEVVSATPHEFTNHIRCHNYANGDTENFTCRICSKVLSSASSLDRHVLVHTGERPFNCRYCHLNFTTNGNMHRHMRTHKQHQASQQQQQQQHSQQQQSNQSNQQQPAQSQSQQQQQRRQQHASGAGATGSGSGSAQLLTTRAESYESDASCSTDVSSELNSHSSNSNQSNHNNNNNNSHKTNNNNNNNSNNNNNNNEDELELEDEQLVLSSKQRRIKAAQNNNNIIRDEEHENRPDDDSDVDSVDSVAQVITSTPDVATLLASGGTSPTHSHSDSHSPPLLLQSCPACNSGEFESVPALCAHLDAEHADIPAKCRECEVIFATHRQLQAHSCRGLPPLLGSSSSPLHKQEESELEEQQQHEENHEQQHKQEEQEQAEQRECEDFFQQLYLKNKSSTTLLPSPIKHEPADQRQDLADIQSILNMTSSSCTSSFLRNFEQSVNTPCSSQYSVDGRDGEEEAQDAFTNEFRRMKLRGEFPCKLCTAVFPNLRALKGHNRYHLSEVGAAGPFRCNMCPYAVCDKAALVRHMRTHNGDRPYECAVCNYAFTTKANCERHLRNRHGKTSREDVKRAIVYHPAEDASCEENKSRTDADMLTELSGYRCATPTEHSSSASSSSQLKHMLLAEPTPAVKVAAAAATTSLPQQPLKIQVKSLDQLVDKPLPALDLSMDALDLSKKPSQLLAEQREHREQLERHELLLQQQQQQQQQQQQQQQQQQQQQQMFGAGDAAAQYMQQLLRSFMLQQSPGFPFFGTAAAAAGAATAATIAAMPLSLPVPLPAGGPVKMVIKNGVLMPKQKQRRYRTERPFACEHCSARFTLRSNMERHVKQQHPQFYALRQRHRSGHHVMRERAASSSAVQAAAAAQAAAAAAAAAAMSNLSQQQQLQQQQQQLQHSHSHHVHAPISEQVKYAILAQQLKARKDTDLLQQALAHGSSSVVTNPLLHFNYNSNNNNSSSKQQQQQLSNNTGNSLVLDDDEPPKLIIDEDDEDVEGEDDEDEEEEQEFDVDEEEQEDEEMDLDDEHQQQPHEDDDDIDNDDDDDDDAAAAAEASQQQLQPTKDKLQSKPIQAAKKVAETILEQANKEREEKASEKPPQSESKSGNKPATPTTMKTMIAQAESVAKSLKEVASSPFKDESQDLVPVAKLVDNATSNQVSFNSYFRPSDVANHMEQSDEEGLVASGSASESNNSGTEDVTSSSSSCGNDTKKKSAYSLAPNRVSCPYCQRMFPWSSSLRRHILTHTGQKPFKCSHCPLLFTTKSNCDRHLLRKHGNVESAMSVYVPTEDVSEPIPVPKSVEEIELEEQRRRQAAEAEQAEREQRERQKERERELELEREREREQQQLIQQLRQQMAAAAAAAVAVAVVAAPTHPPPTPQPAQSPPGLEASSDLPYKCHLCEFSFGERLQCLEHIKQLHAHEFALLLAKGAIETDAQLQHQQQQQLPVAGGAAHSDDEAAAVGTRSGKYPDYSNRKVICAFCVRRFWSTEDLRRHMRTHSGERPFQCEICLRKFTLKHSMLRHMKKHSGRSHNGGELDHQSDCSDDEQLLPCSPPSTPTPTNNNNNNNTCQNNNNNNNNNNNNSNSKQVLRELLGKANEWRVSRLGEHKENIAEATTTPTSATAAAAATAAAAAAAAAAAAAVASGDLIGNLLGISDQGILNKLLSSPDEAAKLLGVEK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00535518;
90% Identity: iTF_00525357;
80% Identity: -