Basic Information

Insect: Drosophila mimica
Gene Symbol: prg
Assembly: GCA_037043585.1
Location: JBAMBE010000585.1:969056-970933[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.14 8.9 6.9 1.2 1 23 229 252 229 252 0.85

2 9 0.0005 0.032 14.6 0.1 1 23 258 281 258 281 0.96

3 9 5.4e-06 0.00035 20.8 0.3 1 23 287 309 287 309 0.97

4 9 1.1e-07 7.2e-06 26.1 4.3 1 23 315 337 315 337 0.98

5 9 2.9e-05 0.0019 18.5 0.6 1 23 343 365 343 365 0.98

6 9 5.9e-05 0.0038 17.5 0.3 1 23 371 393 371 393 0.98

7 9 3.3e-05 0.0022 18.3 0.5 1 23 468 490 468 490 0.96

8 9 7.3e-06 0.00047 20.4 0.4 1 23 495 518 495 518 0.92

9 9 0.015 0.99 9.9 1.0 1 23 522 544 522 544 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.14	8.9	6.9	1.2	1	23	229	252	229	252	0.85
2	9	0.0005	0.032	14.6	0.1	1	23	258	281	258	281	0.96
3	9	5.4e-06	0.00035	20.8	0.3	1	23	287	309	287	309	0.97
4	9	1.1e-07	7.2e-06	26.1	4.3	1	23	315	337	315	337	0.98
5	9	2.9e-05	0.0019	18.5	0.6	1	23	343	365	343	365	0.98
6	9	5.9e-05	0.0038	17.5	0.3	1	23	371	393	371	393	0.98
7	9	3.3e-05	0.0022	18.3	0.5	1	23	468	490	468	490	0.96
8	9	7.3e-06	0.00047	20.4	0.4	1	23	495	518	495	518	0.92
9	9	0.015	0.99	9.9	1.0	1	23	522	544	522	544	0.98

Sequence Information

Coding Sequence: ATGCTTGATTTAATAACGATCGACGAAGGAACACAGAAAAATTATCAAAAGTTAACATCGGAATTAAAGCGATGTCGCTTGTGCCATTCAGGGATAAAATCGACCACAGATTCGCCGAATATTTACGAGGCGTCTGTTTGCTTTGGCCAGgaggaggaagaagaagaaaatggaagaacagaacagaaaaaaatcataattgcCGATGTTTGCCAGAGTGTTTATGGTGTAAAATATGAGCGCCATGAGTTCCTGTCTGAGCACATTTGTTTGCGCTGCCTGGAGATATTGAGGGACTTCTACGAACAACGTCAGTACATGCAGCAGCATGAATTAGAGCTGCAACAGAAcctaaagaaaataattgctGTAGATGCGAAATATCGACCAGGCCTCAATGGCAATCCCGGCGAGTTTGAATTCGTGGAAGGCGAAGAAGGCTGCGTCATTGTCGATGTGGATCCCGAGCAACTGTGCGAGACGAGTGATGACGAATTCGCCGGCTCCGAAGGTGAAGCTGATCTCGATGACGAGGAGTgggacgatgaggatgaggatggaGGAACTCCACAAAATGAAGAAACCGAGATGCCCCTCGGCATGGATGCCGCCCAAATGGCGATGATGCGAGTGCATCAAACGGTCGACACCATCACCCAATTCAATGCGCATCCAAAGAGCGCCTTTCTTTGCCAGTACTGCGATCTGGCCTTCACCTTACAATCGGACTGCCAGCAGCATGAGTTGGCTTCCCACGATGCCTCGGCGCCATACACTTGCAACTACTGTCAGGTAAGATTGACGACACGTCCGGCTTTGATTGCGCACATCAAGGAGCTGCATGACGCCGAACGTCCCTATGTGTGCGCACTGTGCAGCAAGGGATTCGTACGACGTTCGGACTTGAAGAAGCACACAATTGTGCATACGGGCGTGCGTCCGTTCTCGTGCCACGTCTGCTCCAAGAGCTTCTCGCGCAACACCAACCTGACCAAGCACCTGCGCATCCACAGCAGCGTGAAGCCGTTCGTCTGCCAGCAGTGTCCGCGCTCATTTCAAACACCGCTGGAGCTGCTGAAACACACGCGCTCCCATTCCGAAGTGAAACCTTTCCGGTGCGGACGCTGCCCCGCCTCGTTCGCCCGCAAGGATAAGCTATTGATGCATCAGCAGGTGCATCTCAAGCGCGACATcgagcaaaagcaaagtcaaAATCTGCGCATTAATATGATGATGCCAGCAGAGCAGATGCAAGTGCAGATGCCACTGCATCCGTATGTGGAGGCAGATGCATCGGCCCAACAGGCATTACCATCTATACAAGCATATCCCTATCAGCAGCAAACGCCTCCCTCCCCGATGCCTCCAAAAGTGAAACCATCGCCAAAGGTAACGCGCAATTTCCGCTGCGATGTATGTGATCGTGGCTTCCAACGGGAGCGGGATCTGCAGCGCCATCGGGCTCTGCACATGGACACACTATTCACCTGTAAGTTGTGCGGACAGGGCTTTAATCGGCGCGAGCAACTGCAGCGTCACGAGCTTGAGGCTCATGGACCCAGCTATACATGTGCCATTTGCTGCATCACTTTCCTACAGCAGTCGGAGCTAGAAACGCATCTCAAAGTGCACGAGCTGCAGCACAGTGTGGCCAAAAGTACCCAGGAGGCGTTaattgctgccgccgctgtaGTACCGCTAGCTCATCTCTTGGGCGAGCAGACGGGTGCCCCAATGCCAGCCATCGTTCCGGAGCCCGTCCAGCTGCCCAATGTAAGGCCATCCGCAGCTGAAATGTCATTCTATAGCAACATGATACCCACAATGAATCTAGGCTTTTACAGCGAGACGCGTCCCGAAGAGCGCAACGGAGTTTAA
Protein Sequence: MLDLITIDEGTQKNYQKLTSELKRCRLCHSGIKSTTDSPNIYEASVCFGQEEEEEENGRTEQKKIIIADVCQSVYGVKYERHEFLSEHICLRCLEILRDFYEQRQYMQQHELELQQNLKKIIAVDAKYRPGLNGNPGEFEFVEGEEGCVIVDVDPEQLCETSDDEFAGSEGEADLDDEEWDDEDEDGGTPQNEETEMPLGMDAAQMAMMRVHQTVDTITQFNAHPKSAFLCQYCDLAFTLQSDCQQHELASHDASAPYTCNYCQVRLTTRPALIAHIKELHDAERPYVCALCSKGFVRRSDLKKHTIVHTGVRPFSCHVCSKSFSRNTNLTKHLRIHSSVKPFVCQQCPRSFQTPLELLKHTRSHSEVKPFRCGRCPASFARKDKLLMHQQVHLKRDIEQKQSQNLRINMMMPAEQMQVQMPLHPYVEADASAQQALPSIQAYPYQQQTPPSPMPPKVKPSPKVTRNFRCDVCDRGFQRERDLQRHRALHMDTLFTCKLCGQGFNRREQLQRHELEAHGPSYTCAICCITFLQQSELETHLKVHELQHSVAKSTQEALIAAAAVVPLAHLLGEQTGAPMPAIVPEPVQLPNVRPSAAEMSFYSNMIPTMNLGFYSETRPEERNGV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00511438;
90% Identity: iTF_00610063;
80% Identity: -