Basic Information

Insect: Drosophila mimica
Gene Symbol: Hr39
Assembly: GCA_037043585.1
Location: JBAMBE010000477.1:147239-150439[-]

Transcription Factor Domain

TF Family: SF-like
Domain: zf-C4|SF-like
PFAM: AnimalTFDB
TF Group: Zinc-Coordinating Group
Description: The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 3 0.41 3.6e+03 -3.0 12.1 23 206 40 214 26 218 0.46

2 3 2 1.7e+04 -9.1 23.5 23 151 212 340 194 367 0.32

3 3 3.5e-101 3e-97 326.6 13.8 1 408 497 889 497 889 0.86

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	3	0.41	3.6e+03	-3.0	12.1	23	206	40	214	26	218	0.46
2	3	2	1.7e+04	-9.1	23.5	23	151	212	340	194	367	0.32
3	3	3.5e-101	3e-97	326.6	13.8	1	408	497	889	497	889	0.86

Sequence Information

Coding Sequence: ATGCCAAATATGTCGAGCATTAAGACGGAGCAGAGTGTTTCACCCGGTGCCAGTGGCAGCTATCAGCTGCCCGAAAACATGTCGACAGCGACAGTGACGCCAGCgtcgccgcagcagcagcatcagcagcagcagcgtcacaATGTCTCCGTGACGAATATCAAATGTGAACTGGACGAGCTGGCGACGCCAACGAATGGCAACCTGGTGCCGGTCATAGCCAATTATAATAACCAtaatcacaatcacaatcacaatcataGCGGCAGCTTGCGCATTCCCCTCGGTGGCAACGGGGATGAGTCCGATTCGGATGCGGAGCTGGCCAACATTGAGAATCTGAAGGTGCGAAGACGTGCGGCAGACAAGAATGGTCCGCGTCCCATGTCCTGGGAGGGTGAGCTGAGCGAGAACGAAACGAGTGGCGGCGCCGCCGGCGACGAGGAGGAGCTCATGGAAACGGAAACGGTGATCAAGAGCGAggtgagcagcagcaccagcagcagcagcagtgccacAACGATGGCCAGCAGTCAGGTGAACGCCATGTTGCAGCCCATCAAAACCGAACTGGAGCACATAGCCGGTgagatgcaacagcagcagcagcaacaacagcaacatcagcagcagcagcaacaacagcagcaacatcagcagcagcaccaactgcaacaccaacaactgcagctgcagcaacaacaacaattgctgccaCTGAAGCAACAGAGCTATGCACCGaacaacaaactgaaactggcGCCGACGCAAAGTGATCCcatcaatttgaaatatgagccaacgacaacgacaacatctTCGCTGCTCTGCGACAGGAGCAAGTCGAATAGTGGCGGCCATTTGCCACTGTTGCCCGCCAATCCCAGTCCCGATTCTGCCATACATTCCGTCTATACGCACAGCAGCCCCTCCCAATCGCCGCTGACGTCCCGCCACGCCCCCTATACGCCCTCACTGAGCAGGAACAACAGCGATGCGTCGCACAGTAGctgctacagctacagctctGAATTCAGTCCCACCCACTCACCAATTCAGGCGCGTCATGCGCCACCCGCCGGCGTTGCTGCCTTGTTTAGCGGCAATGCAAATGGCGGTGCACTGCATCATCATAGTGTGCTCTATCGGCCACTCAATGTGGATGCCGCACAGGAGGCACAAAATCTCAGCATGGATGCGGGTGGTGCTGCATTGGATGCCAGTGCAACGTTGGCTGCCTCGCCGGCGGGTATCTCGCGTCAGCAGCTGATCAATTCTCCGTGTCCGATTTGTGGGGATAAGATTAGTGGCTTCCACTATGGCATCTTCTCGTGCGAGTCGTGCAAGGGCTTCTTCAAGCGCACCGTCCAGAATCGCAAgaactatgtgtgtgtgcgtggcgGTCCCTGCCAGGTGAGCATCTCGACGCGCAAAAAGTGTCCCGCCTGCCGTTTCGAGAAGTGCCTGCAGAAGGGCATGAAATTGGAGGCGATACGCGAGGATCGCACCCGAGGCGGTCGCTCCACCTATCAATGCTCCTACACGCTGCCCAATTCGATGCTCAGTCCGCTGCTCAGTCCGGATCAGGCGGCAGCCgctgcagccgccgccgccgttgtcaatcagcagcagcagcagcagcaacatcagcaacaccaacagcagcgacttcagcagcatcagcagcagcagcaacaacagcagcaacagcagcaacatggtCCACTCAATGGctttggtggtggtggctccAACTCGCTGCCAGCGAGTCCCAGTCTCGGCGGCGCATCCATCAAGACGGAGCAAGCGGAGCAGCTCAATCATCATACGTCATCATCAACGCGAGCCTCAAGCATTCCACCCCTGCTGCAGGAAATCATGGATGTTGAACATCTCTGGCAATATACCGATGCGGAGTTGGCACGCATTAATCAGCCGCTGTCCTCGTTTGCAACTGGTGGCTCATCGTCGAGCGGCACAGGCGGTTCAAGTTCCGCCGGACAGCATACGGGCAATGCACAACAGATGACCAATCCACTGCTGGCCAGTGCTGGTCTCTCCTCCAATGGCGAGAACGCCAATCCTGATCTGATTGCACACCTCTGCAACGTGGCCGATCATCGCCTCTACAAGATTGTCAAATGGTGCAAGAGTTTGCCGCTCTTCAAGAACATCTCGATTGACGATCAGATTTGCCTGCTCATCAACTCGTGGTGTGAACTGTTGCTCTTCTCCTGCTGTTTTCGATCCGTCGATACGCCCGGCGAGATCAAGATGTCACAGGGCCGAAAGATTACGCTGGCACAGGCTAAAACCAATGGTTTGCAGGCGTGCATTGAGCGCATGTTGAATCTGACCGATCATTTGAGACGCCTGCGCGTTGATCGCTACGAATATGTTGCCATGAAGGTAATCGTGCTGCTGCAGTCCGACACCACAGAACTGCACGAGGCAGTCAAGGTGCGCGAGTGCCAGGAGAAGGCGCTGCAGGGTCTGCAGGCCTACACGCTGGCCCATTATCCCGATACGCCGTCCAAGTTTGGTGAGCTGCTCCTGCGCATACCCGATCTGCAGCGCACGTGTcagCTGGGCAAGGAAATGCTGACGATCAAAACGCGCGATGGAGcagattttaatttgctgaTGGAACTGCTGCGCGGAGAACATTGA
Protein Sequence: MPNMSSIKTEQSVSPGASGSYQLPENMSTATVTPASPQQQHQQQQRHNVSVTNIKCELDELATPTNGNLVPVIANYNNHNHNHNHNHSGSLRIPLGGNGDESDSDAELANIENLKVRRRAADKNGPRPMSWEGELSENETSGGAAGDEEELMETETVIKSEVSSSTSSSSSATTMASSQVNAMLQPIKTELEHIAGEMQQQQQQQQQHQQQQQQQQQHQQQHQLQHQQLQLQQQQQLLPLKQQSYAPNNKLKLAPTQSDPINLKYEPTTTTTSSLLCDRSKSNSGGHLPLLPANPSPDSAIHSVYTHSSPSQSPLTSRHAPYTPSLSRNNSDASHSSCYSYSSEFSPTHSPIQARHAPPAGVAALFSGNANGGALHHHSVLYRPLNVDAAQEAQNLSMDAGGAALDASATLAASPAGISRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYVCVRGGPCQVSISTRKKCPACRFEKCLQKGMKLEAIREDRTRGGRSTYQCSYTLPNSMLSPLLSPDQAAAAAAAAAVVNQQQQQQQHQQHQQQRLQQHQQQQQQQQQQQQHGPLNGFGGGGSNSLPASPSLGGASIKTEQAEQLNHHTSSSTRASSIPPLLQEIMDVEHLWQYTDAELARINQPLSSFATGGSSSSGTGGSSSAGQHTGNAQQMTNPLLASAGLSSNGENANPDLIAHLCNVADHRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLLFSCCFRSVDTPGEIKMSQGRKITLAQAKTNGLQACIERMLNLTDHLRRLRVDRYEYVAMKVIVLLQSDTTELHEAVKVRECQEKALQGLQAYTLAHYPDTPSKFGELLLRIPDLQRTCQLGKEMLTIKTRDGADFNLLMELLRGEH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00575636;
90% Identity: iTF_00595983;
80% Identity: iTF_00548853;