Dmim004105.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila mimetica
Gene Symbol
RREB1
Assembly
GCA_037075245.1
Location
JBAMCH010000005.1:7832600-7838919[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 12 0.034 2.6 8.8 0.8 1 21 227 247 227 249 0.93
2 12 0.00032 0.024 15.2 0.2 1 23 259 281 259 281 0.98
3 12 7.7e-05 0.0059 17.1 7.3 1 23 287 309 287 309 0.98
4 12 2 1.5e+02 3.3 3.7 2 19 534 551 534 553 0.97
5 12 0.009 0.69 10.6 0.9 1 23 689 711 689 711 0.97
6 12 1.2e-05 0.0009 19.7 0.7 1 23 721 743 721 743 0.99
7 12 0.00079 0.061 14.0 2.0 1 23 749 772 749 772 0.97
8 12 0.0028 0.22 12.2 2.0 1 23 1047 1070 1047 1070 0.95
9 12 8.2e-05 0.0063 17.1 0.3 2 23 1433 1454 1432 1454 0.97
10 12 0.14 11 6.9 6.3 1 23 1460 1483 1460 1483 0.97
11 12 0.008 0.62 10.8 0.5 3 23 1677 1697 1675 1697 0.96
12 12 0.0013 0.1 13.3 4.8 1 23 1703 1725 1703 1725 0.99

Sequence Information

Coding Sequence
atgctcgccgcacagcaacagcagcagcagcagcagcacaacaacagcacagCGGACAGCGAGATGGAGCGCCAGCGACGCGACTCCACAACCTCGGAGTCCTCCCTGGAGCACCTGGACCTCGGGCGCACGCCCAAGAAGCTGGGTGGCAGCGGTGGCTCCGCACAGACCACCTCCACGCCCCACGAACTGACGGCGGTGGCGTCGCGCAAGCGCAAACTCcgccaactgcagcagcaaatgaaccaccagcagcagcagcagcatcagcaggatTTGCTGAGCGACGAGGACGATGAGGAGCGGGATGAGCACGAGGATGAGGAGCCCCGGAATCTGGGGCGGCACAAGCAGCGTCGCAGCACCCAGGCCTCCATTGTGATGGACTACAGCACTGCGGATGCCAGTTCGCTGCGCAAGAAGTTCCGTTTGAATCGCTCGGCGGCCAGTCTCTCGGAATCGGGATTCGTGGATGCCAGCAGCACGGCCCACAGTGGCTATCTGGGGAACAGCAGCAGTagtgccaccaccaccaccaccaacgcTCCAGCGGTGGCTCCATCTGGCGGCGGtgcgcccagcagcagcagtagcagcagcagcggcggctcCTCGCCGCAGGGTCTGTGCCTCTCCAGCGGCGAGTCGGGCATCGGTGCGGGGGATGAGCACATGAAGTACCTGTGCCCCATCTGCGAGGTGGTCTCGGCCACGCCGCACGAGTTCACCAACCACATCCGGTGCCACAATTACGCCAACGGCGACACGGAGAACTTCACCTGCCGCATTTGCTCCAAGGTGCTATCCTCGGCCTCATCCCTGGACAGACACGTGCTGGTCCACACGGGCGAGCGGCCCTTCAACTGCCGCTACTGCCACCTGACCTTCACCACCAACGGCAACATGCACCGTCACATGCGCACCCACAAACAGCATCAAGTGGCGCAGTCGcaatcgcagtcgcagtcacagcagcagcagcaacagtcgcagtcacagcagcaacatcagcgccggcagcagcaacaacagcagtcgcagcagcaacagaatcccgcccagcagcagcaacagcagccactGGTGGCCACCGCGCGAGCGGAGAGCTATGAGAGCGATGCCAGCTGCTCCACGGATGCCTCCAGTGGCCATAGTCacagtcgcagcagcagctccctGCAAcaccaccacaacaacaacaacaactcgcACAAGACTAACAACAATCTGAAGGAGCTGGAGCAGGACGAAGTGGTGGAGGATCAGGAGCTGGAGAGCAAGCAGCGTCGACTGAAGACCACGATCAATAACAACATCATCGATAGCCGGGATCAGCAGGATGATGACAACgaggtggaggagcaggaggaagaggaggccGACGATGCGGATGTGGCCATGTTGACCAGCACCCCAGATGTGGCCACTCTGCTGGCCGGAGCCAGTGCCTCTGGAGCCGCCTCTCGCTCGCCATCCCCCTCGCCATCCGCCTCGCCCGCTCCCCTGCTCCTCAGCTGTCCCGCCTGCGGCGCCTCCGATTTCGAGACCCTGCCCGCCCTGTGCGCCCACCTGGATGCCCGGCACTCGGACATCCCAGCCAAGTGTCGCGACTGCGAGGTGATCTTCGCCAGCCACCGCCAGTTGCAGGCCCACTGCTGTCGCGGATCGGTGGGTCTGCCGCTCCTTGGCGCCAGCAGTTCGCCGCTGCACGAGGATGAGcgcgaggatgaggaggaggatctgGAGGATCGCAAGGAGCGTCTACTGCCCAGCCAGAGCGAGGACTTCTTCCAGCAGCTGTATCTGAAGCAGAAGACCAGCGGCATTGGCGCCATCTCCCATCCGCCGTCGCCCATCAAACACGAACCGGCGGACAGCAAGGACCTCGCCGACATACAGAGCATCCTGAACATGACcagctccagttccagtttCCTGCGCAACTTCGAGCAGTCGGTGAACACACCCAGCTCCAGCCAGTACAGCCTGGACGGGCGGgatcaggaggaggaggcccaGGATGCGTTCACCTCGGAGTTTCGGCGCATGAAGCTGCGCGGCGAGTTCCCCTGCAAGCTCTGCAGCTGCGTCTTTCCCAATCTGCGCGCCTTGAAGGGTCACAATCGTGTCCATCTGGGCGCCGTGGGTCCCGCTGGTCCATTCCGCTGCAACATGTGCCCCTATGCCGTGTGCGACAAGGCCGCTCTGGTGCGTCACATGCGCACCCACAATGGGGATCGCCCATATGAGTGCGCCGTCTGCAACTACGCCTTCACCACCAAGGCGAACTGTGAGCGCCACCTGAGGAATCGCCATGGGAAGACATCGCGGGAGGAGGTGAAGCGAGCCATTGTCTATCATCCGGCAGAGGATGCGGGCTGCGATGCGGATAGCAAGTCCAGAATGGGCGAGGATCTGGCTGATTTGAGTTTCCGTTCGATCAGCCCcacgccgccaccgccaccagtGGCTCCGCTGGCCAGCGAGAGTAGCTCCTCCCAGCTGAAGCACATGCTGCTGGGCGAGAGTCACCATCAgccggcggcggcagcggtggCGCCTCCTCTGAAGATTCAGGTGAAGAGTTTGGACCAACTGGTGGACAAGAAGCCAGCGGTGGCTAATcctccccagcagcagcagcaggagaaggcTGCCCTGGACTTTAGCATGGATGTGCTGGATCTCAGCAAGAAGCCAACgagtggaggaggaggaggtggagctgCGCCCACTCCCACGCCCGCTTTGGTGCCTGGCCCTCCGGCCGATCTGACCGCCGCCCtggagcagcaacagttgctcctcgcccagcagcagctctTCGGCGCCGCCGGCGGAGATGCTGCCTCGCAGTACATGCAGCAGCTGTTCCGCAGCCTGATGTTCCAGTCGCAGGCCTCGGGCTTCCCCTTCTTTCCCTTCATggcgccaccgccgccgcagcagcagcagcagccgccagTGAATCCGGAGAAGGCGCCGCTGGTGAGTCCGCCCAGCCGCCTGAATCCGCTGAATCCCCTGCccgtgggtgtgggtgtgccCGTGCCACCTGGCGGTCCCGTCAAGATGGTCATCAAGAACGGGGTGCTGATGCCCAAGCAGAAGCAGCGACGCTATCGCACGGAGCGACCCTTCGCCTGTGAGCACTGCTCGGCAAGATTCACGTTGCGCTCGAACATGGAGCGTCATGTGAAGCAGCAGCATCCACAGTTCTATGCTCAAAGGCAGAGGAGTGGCCACCATGTGATGCGGGGCAGGGGAGCCTCCAGtgcggctgccgctgccgccgccgctgccgctgcagcagctgccatgggtccaggaggaggagcaggagcaggagcaggagttgCCTCCTCCAATCACGCTCATCATGGCCATCATGCGCCCATTTCGGAGCAGGTCAAGTACGCCATTCTGGCCCAGCAGCTGAAGGCGCACAAGAACACCGATCTGCTGCAGCAGGCACTGGCCCATGGCTCCAGCGCAGTGGCCGGGAATCCCCTCCTGCACTTTGGTTATCCCCTGACCCAGCCCAGTCCCCTGCACAATGGGGGCAATGGTCACCTACACCCAGCCATGGATGACGATGAGCCCAAGCTGATCATCGATGaggatgataatgatgatcaTGAGGTGGAGGCGGAGCCGGAAGATGATtttgaggaggaggaggacgaggaggaggagttggATGAGCCCATGGAGCTGGAGGAGCCCGAGGAGcaggccgccgccgccggcgaggaggcggaggaggaggccgacgaggagcaggagctgcccAAGCCCCTCGAGCAGTTGTCGTCGCCCGTCAAAGAGGCGGCGGAGACCATCCTGGAGCAGGCCATCAAGGCGGGCAAGCCATCGAGTCCACAGGAGCCTCTTGTCGAGTCAGCGGAGGAGCAGGTCACCCCCAAGGTGGTGGTTACCATGCAGGAGCCGGCGCCTTCGAGCAACCCGAGCAGTTTGAAGACCATGATTGCCCAAGCCGAGTCGGTGGGCAAGTCCCTCAAAGAGGTGGCCAGTTCGCCGTTCAAGGACGAGTCACAGGACCTCGTGCCGGTGGCCAAGCTGGTGGACAATGCCACCAGTCAGACGATGAGCTTCAACAGCTACTTCCGGCCCAGTGATGTGGCCAATCACATGGAGCAGAGCGACGAGGAGGGCTTGGTGGCCTCCGGCAGTGCCAGcgagagcaacaacagcggcacCGAGGATGTCACGAGCAGCAGTTCGTCCAGTGAACCCAAGAAGAAGTCCGCCTACAGTTTGGCACCCAATCGCGTCTCGTGTCCCTACTGCCAGCGCATGTTCCCCTGGAGCAGTTCCCTGCGCCGCCACATCCTCACGCACACGGGGCAGAAGCCCTTCAAGTGCTCCCACTGCCCGCTGCTGTTCACCACCAAGAGCAACTGCGACCGCCATCTGCTGCGCAAGCACGGCAACGTGGAGTCGGCCATGTCGGTGTATGTGCCCACCGAGGATGTGAGTGAACCGATACCGGTGCCCAAGTCGGTGGAGGAGATtgagctggaggagcagcgTCGCCGGCAGGAGGCGGAGCGTGAGAAGGAGCGGGAATTGGAGCGGGAGAGGGAGTTGGAGCGGGAAAGGGAGCTGGAGCGGGAGCGCGagctggagaaggagaaggagcgcGAGCGACAGCAGCTCATCCAGAAGCTGGCGGCCCAAATGaatgccgctgctgctgccgccgccgccgctgcagctggaggagcacCCGTGGCGGATGCCCTGGCTGGCGGAGATCTGCCCTACAAGTGCCACCTGTGCGAGGGCTCCTTTGGCGAGCGGCTGCAGTGCCTGGAGCACATCAAGCTGGCCCATGCCCACGAGTTTGCCCTGCTCCTGGCCAAGGGTGCCATTGAGAACGAGTCGCTGGAGTCGTCTAATCCCCACCAGCAGCAGTCTGGCATCCATTCCGATGATGAGGCTCccaacggcggcggcggcggcagtcGCGGCAAGTATCCCGACTACAGCAACCGCAAGGTGATCTGCGCCTTCTGTGTGCGCCGCTTCTGGTCCACCGAGGATCTGCGTCGCCACATGCGCACCCACTCCGGCGAGCGGCCCTTCCAGTGCGACATCTGCCTGCGCAAGTTCACGCTGAAGCACAGCATGCTGCGGCACATGAAGAAGCACAGTGGACGCGCCCACAATGGCGACAATGCGGGATCCGATTGCTCGGATGATGAGCAGGCCATGAGCAGTCCACCCAGCACTcctgttcctgctgctgcagctgctcctgctcctcctgcttctaccaacaacaacaacaacagctgtcacgtaaacaacaacaacgcggGATCCAAGCTGGGCTTGAAGCTGCCCAAGCTCCATGAGCTGCTGGACAAGGCCAGCGAGTGGCGAGCCAGTCGTCTGGGCGAGCACAAGGAGAACCTGGGCGAGGCATCGCCCTCGCCGGCAGCCGTCGCTGGATCGGATCTGATTGGCAATCTGCTGGGCATCAGCGACCAGGGCATCCTCAACAAGCTGCTCTCCTCCGCCGACGAGGCGGCCAAGCTCCTGGGCGTGGACAACAAGTGA
Protein Sequence
MLAAQQQQQQQQHNNSTADSEMERQRRDSTTSESSLEHLDLGRTPKKLGGSGGSAQTTSTPHELTAVASRKRKLRQLQQQMNHQQQQQHQQDLLSDEDDEERDEHEDEEPRNLGRHKQRRSTQASIVMDYSTADASSLRKKFRLNRSAASLSESGFVDASSTAHSGYLGNSSSSATTTTTNAPAVAPSGGGAPSSSSSSSSGGSSPQGLCLSSGESGIGAGDEHMKYLCPICEVVSATPHEFTNHIRCHNYANGDTENFTCRICSKVLSSASSLDRHVLVHTGERPFNCRYCHLTFTTNGNMHRHMRTHKQHQVAQSQSQSQSQQQQQQSQSQQQHQRRQQQQQQSQQQQNPAQQQQQQPLVATARAESYESDASCSTDASSGHSHSRSSSSLQHHHNNNNNSHKTNNNLKELEQDEVVEDQELESKQRRLKTTINNNIIDSRDQQDDDNEVEEQEEEEADDADVAMLTSTPDVATLLAGASASGAASRSPSPSPSASPAPLLLSCPACGASDFETLPALCAHLDARHSDIPAKCRDCEVIFASHRQLQAHCCRGSVGLPLLGASSSPLHEDEREDEEEDLEDRKERLLPSQSEDFFQQLYLKQKTSGIGAISHPPSPIKHEPADSKDLADIQSILNMTSSSSSFLRNFEQSVNTPSSSQYSLDGRDQEEEAQDAFTSEFRRMKLRGEFPCKLCSCVFPNLRALKGHNRVHLGAVGPAGPFRCNMCPYAVCDKAALVRHMRTHNGDRPYECAVCNYAFTTKANCERHLRNRHGKTSREEVKRAIVYHPAEDAGCDADSKSRMGEDLADLSFRSISPTPPPPPVAPLASESSSSQLKHMLLGESHHQPAAAAVAPPLKIQVKSLDQLVDKKPAVANPPQQQQQEKAALDFSMDVLDLSKKPTSGGGGGGAAPTPTPALVPGPPADLTAALEQQQLLLAQQQLFGAAGGDAASQYMQQLFRSLMFQSQASGFPFFPFMAPPPPQQQQQPPVNPEKAPLVSPPSRLNPLNPLPVGVGVPVPPGGPVKMVIKNGVLMPKQKQRRYRTERPFACEHCSARFTLRSNMERHVKQQHPQFYAQRQRSGHHVMRGRGASSAAAAAAAAAAAAAAMGPGGGAGAGAGVASSNHAHHGHHAPISEQVKYAILAQQLKAHKNTDLLQQALAHGSSAVAGNPLLHFGYPLTQPSPLHNGGNGHLHPAMDDDEPKLIIDEDDNDDHEVEAEPEDDFEEEEDEEEELDEPMELEEPEEQAAAAGEEAEEEADEEQELPKPLEQLSSPVKEAAETILEQAIKAGKPSSPQEPLVESAEEQVTPKVVVTMQEPAPSSNPSSLKTMIAQAESVGKSLKEVASSPFKDESQDLVPVAKLVDNATSQTMSFNSYFRPSDVANHMEQSDEEGLVASGSASESNNSGTEDVTSSSSSSEPKKKSAYSLAPNRVSCPYCQRMFPWSSSLRRHILTHTGQKPFKCSHCPLLFTTKSNCDRHLLRKHGNVESAMSVYVPTEDVSEPIPVPKSVEEIELEEQRRRQEAEREKERELERERELERERELERERELEKEKERERQQLIQKLAAQMNAAAAAAAAAAAGGAPVADALAGGDLPYKCHLCEGSFGERLQCLEHIKLAHAHEFALLLAKGAIENESLESSNPHQQQSGIHSDDEAPNGGGGGSRGKYPDYSNRKVICAFCVRRFWSTEDLRRHMRTHSGERPFQCDICLRKFTLKHSMLRHMKKHSGRAHNGDNAGSDCSDDEQAMSSPPSTPVPAAAAAPAPPASTNNNNNSCHVNNNNAGSKLGLKLPKLHELLDKASEWRASRLGEHKENLGEASPSPAAVAGSDLIGNLLGISDQGILNKLLSSADEAAKLLGVDNK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00605068;
90% Identity
-
80% Identity
-