Dmim004709.1
Basic Information
- Insect
- Drosophila mimetica
- Gene Symbol
- -
- Assembly
- GCA_037075245.1
- Location
- JBAMCH010000005.1:15107781-15110085[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 10 0.16 12 6.7 0.1 2 23 278 300 278 300 0.90 2 10 6e-05 0.0046 17.5 0.3 6 23 309 326 309 326 0.99 3 10 1.6e-05 0.0012 19.3 0.3 1 23 332 355 332 355 0.98 4 10 4.9e-05 0.0037 17.8 0.4 1 23 367 389 367 389 0.97 5 10 0.022 1.7 9.4 6.6 1 23 396 419 396 419 0.97 6 10 7.2e-05 0.0055 17.2 1.9 1 23 425 447 425 447 0.96 7 10 0.096 7.4 7.4 0.5 2 23 456 477 455 477 0.96 8 10 8.2e-05 0.0063 17.1 2.3 2 23 483 505 482 505 0.95 9 10 6e-06 0.00046 20.6 0.9 2 23 512 533 511 533 0.96 10 10 0.00019 0.014 15.9 4.4 1 23 539 562 539 562 0.96
Sequence Information
- Coding Sequence
- ATGATTTGTCGCCTGTGCCTGCGGTGTCTCAGTCCCGGGAGCGCCGTCTTCCTCTTCGAAACGGACGATACGCTGGCTGAGACGCGCCTGGTGAAGATGATCGCCAAGTTTCTGCAGCTGGAGATCCTGCCCGATGATGGCATCTCGACCAGCGTGTGCACCGATTGCTGCGAGCATTTGGAGGACTTCAATGGCTTCTGGCAGCTGGTGGAGCAGAAGCAGTGCTCCCTCAAGAAGGAGTTCCTCACCGTCGACGTCGACTGCGCAGCGATGAAGTGGACGGGCGGCGTCGACGTGGACGTCAACATCGACGAGCTGCCGCTGGCTGCGGGCGACATGGACGAGAAGCCGCTGGACCTGCACAACCTGAGCCTGCTGGGCAGCGTGCTGGACGTGAATGTGGACAGCGTGGAGGTCAGGGAGCAGCAGGGCAAGGAGCCGCTGCCCTGTGAGTCCGAGGCGGAGGACGAGAAGCCCTGTTTGCTGGCCAGTGATAGCGAACCGGAGGCGCAGCCCGATGAGGACTCCTCGGATGATGAACCCCTGGTGCGGCTGCAAACCAAGATGAGACCCAAGCCACCCAAACGCAAGGCCAAGATCAAGCAACGCCACACCGAGAGCGCACATTCCCTGCACCGGGAGCTGGAGAATCTGCTCGACGACGACGGCAGCAAGCGGCGACGCCGCAGGGCAGCCGGCGAGCAGCAGCGAGCGCCCACCGAGGTGCAGGAGTCCGAGCTGCAGGCCGTCCTCGAGCGCAAGCCCAAGGGCTGCTCCCGCGCCCAGCTGGCCAAGAGCTACGAGGAGGCCATCGCCAGCTACATGAGCGCCAGCTGCGACCTGTGCGACTTTAGCGCTCCCTACCTCTCCGAGCTGAAGACTCACTTCCTGGAGGCGCACCAGCGCGAGTACTACATCAAGTGTTGCGGCAAGATCTTCACGCGCGCTTCCAAGCTTATGGATCACATCCGCAAGCATGTCAATCCCAAGCTATTTACCTGCTCCATTTGCCAGAAGTCACTCAACTCGCAGGACTACCTGGCCACCCACATCGAGACGGTGCACAACAAGGTCGCGCAGATCGACAAGGTGCTCAAGTTCCCCTGTCCCAAGTGCGAACGAACCTTCAGCAGCGAGCGGCGATTGGCCAACCATTTGGCCAAGCACGACACCGATCAGCTGGATCACACCTGCAAGATCTGCTGCAAGAGCTTTGCCAACATACACAGGCTGCGACGCCACATCCAATCCATCCACGAGGACCTGCATCGTCACGTTTGCGACATCTGCGGCAAGAAGTTCAAGTTCAAACCCTCCTTCGATCGCCACCTGCTGGAGCACCAGGGCGTGGTGGCGCCGGCAATGGAGTGCCCCGTTTGTGGAGTGTGGCTGAAGAACGAGCACAGCCTGCGACTGCATCGATTCACGCACGACAGCACGGACACCGTGTGTCCGCACTGCGGCAAGACCTGCACCTCGCGCACAGCGCTCCGGGGGCATGTGAAGTACGCCCACAAGCTGACCACCAATCTGCAGTGCACGTTCTGCGAGAAGACCTTCAAGCAGCAGCGCAACCTGGACGAGCACATGGCCATACACACGGGCCTGCAGCTGTACAACTGCCCGCATTGCCCCAAGGAGTGCCGCTCGCGCTCTAATATGTATGTCCACATCAAGCAGCGGCATGCGGACGAGTGGCTGCGCGCCAAAATGGCACGTTCGCACAATCCCCAGTTCAAGCCGGGATCCAGCGACGTTTAA
- Protein Sequence
- MICRLCLRCLSPGSAVFLFETDDTLAETRLVKMIAKFLQLEILPDDGISTSVCTDCCEHLEDFNGFWQLVEQKQCSLKKEFLTVDVDCAAMKWTGGVDVDVNIDELPLAAGDMDEKPLDLHNLSLLGSVLDVNVDSVEVREQQGKEPLPCESEAEDEKPCLLASDSEPEAQPDEDSSDDEPLVRLQTKMRPKPPKRKAKIKQRHTESAHSLHRELENLLDDDGSKRRRRRAAGEQQRAPTEVQESELQAVLERKPKGCSRAQLAKSYEEAIASYMSASCDLCDFSAPYLSELKTHFLEAHQREYYIKCCGKIFTRASKLMDHIRKHVNPKLFTCSICQKSLNSQDYLATHIETVHNKVAQIDKVLKFPCPKCERTFSSERRLANHLAKHDTDQLDHTCKICCKSFANIHRLRRHIQSIHEDLHRHVCDICGKKFKFKPSFDRHLLEHQGVVAPAMECPVCGVWLKNEHSLRLHRFTHDSTDTVCPHCGKTCTSRTALRGHVKYAHKLTTNLQCTFCEKTFKQQRNLDEHMAIHTGLQLYNCPHCPKECRSRSNMYVHIKQRHADEWLRAKMARSHNPQFKPGSSDV
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00492388;
- 90% Identity
- iTF_00505566;
- 80% Identity
- -