Basic Information

Insect: Drosophila micromelanica
Gene Symbol: Hr39
Assembly: GCA_004143905.1
Location: SCDX01000996.1:65026-69448[-]

Transcription Factor Domain

TF Family: SF-like
Domain: zf-C4|SF-like
PFAM: AnimalTFDB
TF Group: Zinc-Coordinating Group
Description: The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 4 0.4 3.1e+03 -3.0 0.6 142 159 23 40 3 84 0.49

2 4 2 1.5e+04 -5.3 24.7 39 159 183 310 159 330 0.56

3 4 0.2 1.5e+03 -2.0 4.0 52 126 284 356 270 406 0.73

4 4 7.2e-101 5.5e-97 325.5 12.9 1 408 475 867 475 867 0.86

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	4	0.4	3.1e+03	-3.0	0.6	142	159	23	40	3	84	0.49
2	4	2	1.5e+04	-5.3	24.7	39	159	183	310	159	330	0.56
3	4	0.2	1.5e+03	-2.0	4.0	52	126	284	356	270	406	0.73
4	4	7.2e-101	5.5e-97	325.5	12.9	1	408	475	867	475	867	0.86

Sequence Information

Coding Sequence: ATGCCCAACATGTCGAGCATTAAGACGGAGCAGAGCGTTTCTCCACCCGGTGCCAGCGGCAGCTATCCGGTCAATATgtcgacgatgacgacgacgacgtcgatgACAACAACCGGAACGGGCACCGTGCGCGGTCACAATGTGTCCGTGACGAACATCAAGTGcgagctggaggagctgcCGACGCCGAATGGCAACCTGGTGCCCGTTATAGCCAActataataatcataatcacAATCACAATCATAATCATAGCGGCGGGGGCGGCAGCCTGCGGATACCGTTGGGCGGCGGCAAAGAGGACGAATCCGATTCGGAGGCGGAACTGGCCAACATTGAGAATCTGAAGGTGCGAAGACGGGCGGCCGATAAAAACGGGCCGCGTCCCATGTCCTGGGAGGGTGAGCTCAGCGAGCCGGAGACGAACAACGGCGAGGAGCTCATGGAAACGGAGACGGTGATCAAAAGCGAGCAAACCTCAGCGATGCTGCAGCCGATCAAGACCGAACTGGAGCAGATAGCCGGAGagatgcaacagcagcaacagcaactgctgcagcagcagcagcagcagcagcagcaacaacagcaacagcagaagcaacaacaactgcagcaacaacaacagcagcaactgcaaatgcagcCTCTTAAGCAACAAAGTTTTGCGCCGAACAAACTGAAGTTGGCGCCGACGCAAAGCGATCCCATCAATCTGAAGTACGAGCCGACGACGTCGTCCCTCTGCGAGCGGAGCAAGTCGAGCAGTGGCGGACATTTGCCGCTGTTGCCGGCCAATCCCAGTCCCGATTCTGCCATACATTCCGTTTATACGCACAGCAGcccgtcgcagtcgccgctgACGTCGCGGCACGCCCCCTACACGCCCTCGCTGAGCAGGAACAACAGCGACGCCTCGCACAGCAGCTGCTACAGCTACAGTTCCGAGTTCAGTCCCACCCACTCGCCCATTCAGGCGCGCCACGCCCCGCCCGCCGGCACCGCCCTGTTTCCCGGGAATGGAACGGCCAATGCGTCCACGGCTGGTGCACTGCATCATCACAGCGTGCTGTATCGGCCGCTCAATGTGGACGCCTCGGTTGCCGGCCAGGAGGCGCAAAATCTCAGCATGGATGCGACACCGTTGGACGCAACGGCGACGCTGCCCGCCTCCCCGGCGGGCATCTCGCGCCAGCAGCTGATTAATTCGCCGTGTCCGATCTGCGGCGACAAGATCAGCGGCTTCCACTATGGCATCTTCTCCTGCGAGTCGTGCAAGGGCTTCTTCAAGCGCACCGTGCAGAATCGCAAGAACTATGTGTGCGTCCGGGGCGGGCCCTGCCAGGTGAGCATCTCCACGCGCAAGAAGTGCCCGGCCTGCCGGTTCGAGAAGTGCCTGCAGAAGGGCATGAAACTGGAGGCGATACGCGAGGATCGCACACGTGGCGGCCGATCCACCTATCAGTGCTCCTACACGCTGCCCAACTCGATGCTCAGTCCGCTCCTCAGTCCGGATCAGGCGGCTgttgccgcagcagccgccgcagttgccaatcagcagcagcaacaccaacagcaacagcagcaacagcaacagcagcaacatcagcaacaacatcagcagcagcgattgcatcagcaacagcaacatcatcaacacCAACACGGTTCACTCAATGgctttggcggcggcggcggcggaggagGCTCCAATTCACTGCCGGCCAGTCCCAGTCTCGGCGGCGCATCCATAAAAACGGAGCAGGCGGAGCCGATCAGCCATCGCATTCCAGCCCTGCTGCAGGAAATCATGGATGTGGAGCATCTCTGGCAATATACCGATGCGGAATTGGCGCGCATCAATCAGCCGCTGTCCTCGTTCGCATCTGGGGGCTCCTCGTCGAGCGCCGCGGGCGGTTCGAGTTCCGCCGGACAGCACACTGCCAATGCCCAACAGATGACCAATCCACTGCTGGCCAGTGCTGGTCTCTCGTCCAACGGCGAGAACGCCAATCCCGATCTGATCGCACACCTCTGCAACGTGGCCGATCATCGGCTCTACAAGATCGTTAAATGGTGCAAGAGTTTGCCACTCTTTAAGAACATATCGATTGACGATCAGATCTGCCTGCTCATCAACTCGTGGTGTGAACTGCTGCTCTTCTCCTGCTGTTTTCGTTCCATCGATACGCCTGGCGAGATCAAAATGTCACAGGGCCGGAAAATTACCCTGGCACAGGCTAAAACCAATGGCCTACAGGCCTGCATTGAACGCATGCTGAATCTGACTGATCACTTGCGACGCCTGCGTGTTGATCGCTACGAATATGTTGCCATGAAGGTAATCGTGCTGCTGCAGTCCGATACCACGGAACTGCATGAGGCGGTCAAGGTGCGCGAGTGCCAGGAGAAGGCGCTGCAGGGCCTGCAGGCGTACACGCTGGCCCATTATCCCGATACGCCGTCCAAATTTggtgagctgctgctgcgcataCCCGATCTGCAGCGCACGTGTCAGCTGGGCAAGGAAATGCTGACGATCAAGACGCGCGATGGCGCGGATTTCAATTTGCTGATGGAGCTGCTGCGCGGAGAGCATTGA
Protein Sequence: MPNMSSIKTEQSVSPPGASGSYPVNMSTMTTTTSMTTTGTGTVRGHNVSVTNIKCELEELPTPNGNLVPVIANYNNHNHNHNHNHSGGGGSLRIPLGGGKEDESDSEAELANIENLKVRRRAADKNGPRPMSWEGELSEPETNNGEELMETETVIKSEQTSAMLQPIKTELEQIAGEMQQQQQQLLQQQQQQQQQQQQQQKQQQLQQQQQQQLQMQPLKQQSFAPNKLKLAPTQSDPINLKYEPTTSSLCERSKSSSGGHLPLLPANPSPDSAIHSVYTHSSPSQSPLTSRHAPYTPSLSRNNSDASHSSCYSYSSEFSPTHSPIQARHAPPAGTALFPGNGTANASTAGALHHHSVLYRPLNVDASVAGQEAQNLSMDATPLDATATLPASPAGISRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYVCVRGGPCQVSISTRKKCPACRFEKCLQKGMKLEAIREDRTRGGRSTYQCSYTLPNSMLSPLLSPDQAAVAAAAAAVANQQQQHQQQQQQQQQQQHQQQHQQQRLHQQQQHHQHQHGSLNGFGGGGGGGGSNSLPASPSLGGASIKTEQAEPISHRIPALLQEIMDVEHLWQYTDAELARINQPLSSFASGGSSSSAAGGSSSAGQHTANAQQMTNPLLASAGLSSNGENANPDLIAHLCNVADHRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLLFSCCFRSIDTPGEIKMSQGRKITLAQAKTNGLQACIERMLNLTDHLRRLRVDRYEYVAMKVIVLLQSDTTELHEAVKVRECQEKALQGLQAYTLAHYPDTPSKFGELLLRIPDLQRTCQLGKEMLTIKTRDGADFNLLMELLRGEH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00575636;
90% Identity: iTF_00547406; iTF_00561087; iTF_00561068;
80% Identity: iTF_00547406;