Dmet006109.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila mettleri
Gene Symbol
RREB1
Assembly
GCA_035047625.1
Location
JAWNPI010000068.1:3779843-3786276[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 13 0.016 1.1 9.8 1.7 1 21 245 265 245 267 0.96
2 13 0.00032 0.022 15.2 0.2 1 23 277 299 277 299 0.98
3 13 7.8e-05 0.0053 17.1 7.3 1 23 305 327 305 327 0.98
4 13 0.043 2.9 8.5 0.8 2 20 554 572 554 574 0.93
5 13 0.0085 0.58 10.7 0.1 1 23 731 753 731 753 0.97
6 13 4.9e-05 0.0033 17.7 0.7 1 23 763 785 763 785 0.98
7 13 0.0008 0.054 13.9 2.0 1 23 791 814 791 814 0.97
8 13 0.0029 0.19 12.2 2.0 1 23 1066 1089 1066 1089 0.95
9 13 8.3e-05 0.0056 17.0 0.3 2 23 1437 1458 1436 1458 0.97
10 13 0.14 9.5 6.9 6.3 1 23 1464 1487 1464 1487 0.97
11 13 3.1 2.1e+02 2.6 4.2 1 23 1616 1639 1616 1639 0.88
12 13 0.0081 0.55 10.8 0.5 3 23 1706 1726 1704 1726 0.96
13 13 0.0013 0.087 13.3 4.8 1 23 1732 1754 1732 1754 0.99

Sequence Information

Coding Sequence
atGCTGGccacacagcaacagcagcagcagcagccgcagcagcaacatgcagcaacagctgctgcagctgcagcatctgcAGTAACTCTTGAGGATGCTGTTATGGAGCGACAGCGGCGCGACTCCAGCACCTCGGAGTCGTCGCTGGAGCATCTCGATCTGGGACGCACGCCCAAgaagctgagcagcagcaacggcgcgCCGCAGCCGACGTCAACGCCGCACGTTGAGGCGACGTCGCGCAAACGCAagatgcggcagcagcaacagatgcAAATCGTTTACTCTGACGAGGAggacgaacagcagcagcagcaacagcaacagcatcagcagcagcaacagttgctggaGCAGTCGGTGCAGCGCACACGCCACAAGCAGCGACGCAGCGGCAACGCAGTCGCGGCAGCGGCCAGCGCCAGCATCGTCCTCGACTATAGCGTCGGCAGCGACGCCAGTTCGCTGCGCAAAAAGTTTCGCCTGAatcgcagcagcatcagcgccCACAATGGCGACCTCTCCGAGTCGGGCTTCGTCGATAGCAGCGCGCTCAGCGGCTTTTTGCTGGGCTCCAGCGGCGCCGCGCAGTCGGCGacggcagcgcagcagcagcagcaacagcaacagcagcagcagggttCGGGCAGCAGCTCGGGCGGCTCCTCGCCACAAGGCCTGTGCCACTCGAGCGCCGAGTCCGGCATCAGCGCCGGCGACGAGCACAAGAAATACGTCTGCCCCATCTGCGAGGTTGTCTCGACCACGACCCACGACTTCACCAATCACATTCGATGCCACAACTATGACAACGGCGACACCGAGAATTTCACCTGCCGCATCTGCTCCAAGGTGCTCTCGTCGGCCTCCTCGCTGGACAGGCACGTCCTGGTGCACACCGGGGAGCGACCCTTCAACTGTCGCTACTGCCACTTGACCTTTACGACCAACGGCAACATGCATCGGCACATGCGAACACAcaagcaacatcagcagcagcagcagcagacacagcagcaacagcagcagcagcaggcacagcagcaacagtcacagcagcagcaggcacagccgcagccacagcagcaacagttgcagcggCATCAGCAACATGCGACATCAAATTCTGTGGCTCAACGGGCCGAGAGCTATGAAAGCGACGCCAGCTGCTCCACGGACatatccagcagcagcagcagcagcagcagtgcagccagcaacaacaacaacaacagcagccaagcgaacaacaacaacaacaacaacagcagcagtgagGAGCCgcaactgctgctggcgtgcaagcagcaacagctgaagacgaacatcaacaacaacaacatcatcgtGAGCGACGAGCGTGCGCTGGATACAGATGGAGAcggcgaaggcgaaggcgaaggcgttggcgatggcgatggcgatggcgatgctGAGGGAAGCGATGCAGTCGATGTGACGCAGATGATAACGAGCACGCCCGACGTGGCCACGTTGCTGGCGACGTCGTCGGGCAACAGCAGCCCGCGTacgccggagccggagccggagtcGGAGTCAGGCGCGCTGCCCAGCTGCCCCGCGTGCAGTGACGATGGGTTCCAGACGCTGGCGGCGCTGTACGGGCACCTGGAGACGGAGCACGCCGATATACCCGCCAAGTGCCGCGAGTGCGAGGTAATCTTTGCCAcgcagcgccagctgcaggCGCACAGCTGTCGCGGCCTGCAGTTTCCGCCGCTGCTGGGCGCCAGCTCCTCGCCGCTGCACAAGCAGGAGCCGGCGGACGTGGACGAGCAGGAGCAagacgagcagcagctgcagcaccagcaccagcacgaCATCGCGTCAGAGGCCAtggacgaggaggaggagcagcggctgcagcgcgTCTCGAACAGCGAACGCGACGAGTTCTTTCAGCAATTATATCTGAGGGGCAAGGCGGACGGCTCCTCGCTGCCGTCGCCCATCAAGCACGAGCCGTCGGAGCAGCGCCAGGATCTAGCCGACATACAGAGCATACTGCATAtgaccagctccagctgcacgTCCAGCTTCCTGCGCAACTTCGAGCAGAGCGTGAACACGCCCTGCTCCAGCCAGTACAGCCTCGATGGCCGCGACGGCGAGGAGGAGGCCCAGGATGCGTTCACCAGCGAATTCCGGCGCATGAAGCTGCGCGGCGAATTCCCCTGCAAACTCTGCTCGGCCGTCTTTCCCAATCTGCGTGCGCTCAAGGGCCACAATCGCGTCCACCTGGCAGCCGTCGGCGCCGCCGGGCCCTTTCGCTGCAACATGTGCCCCTACGCCGTCTGCGACAAGGCGGCGCTGGTGCGGCACATGCGCAACCACAACGGCGACCGGCCGTACGAGTGCGCCGTCTGCAACTACGCCTTCACCACGAAGGCCAACTGCGAGCGGCATCTGCGCAATCGGCACGGCAAGACCAGCCGCGACGAGGTGAAGCGCGCCATCGTCTATCATCCGGCCGAGGATGCCAGCTGCGAGGAGATCAAGCCCAAGCTGGATCTGGATCTGTCGGAGCACAGCTACCGCTCGGTCAGCCCCTCGCCGTCGGCCACAAACGTTGAGGCGAGCTCCCAGCTGAAGCACATGCTGCTGGCCGAGCAGcccagcaagcagcagcaggcgacgTCGCAGCCGCCGTTGAAGATTCAGGTGAAGAGCCTCGATCAGCTGGTGGAGAAGCCGCTGGCGCCGGCCATGGACCTCAGCATGGATGTGCTGGATCTGAGCAAGAAACCGCAGCGCGAACATGACTTgctcctgcagcagcagcagcagcagcagcagcagcagcagcagcaacagcagcaacagcagcagcaacagcagcagcaacagttgctctTCAGTCCGGGCGATGCGGCCAAGCAGtacttgcagctgctgcacaacCTGATGATGCAGCAATCGTCCGGGTTTCCGGCCTTGTTCGGCTtgatgccgccgccgccggccGCTGCGCTGGAGAAGTCAGCGGCAGCGATTGCGGCGCCAGCGACAGCGGCCGCGGTGGCCGCAGTGCCGCCACCGCTGGGTCTGCCGCTGGCCGGGCTGGGCGTGCCCGTGCCGGTGCCCGTGCCGCCGGCCGGGCCCGTCAAGATGGTCATCAAGAACGGCGTGCTGATGCccaagcagaagcagcggcgCTACCGCACCGAGCGGCCCTTCGCCTGCGAGCACTGCTCGGCGAGATTCACGCTGCGCTCCAACATGGAGCGCCACgtcaagcagcagcatccgCAGTTCTATGCGCAGCGCCAGCGCAGCGGCCACCACGTGATGCGTGGCCGTGCGGCCAACTCgggcgcagccgcagccgcagcagcagcagcggcggcggcagcagcagcggcagccctAACCAATATGCACCAGCAGcacccacagcagcagcagcaccagctccagcaccagcagcagcaccaccagcaacagcagcagcacgcgcCCATATCGGAGCAGGTGAAATATGCGATTCTggcgcagcagctgaaggCGCGCAAGGATACGGATCTGTTGCAGCAGGCGCTGGCCCATGGCTCCAGCAGCGTGCATCCCCTGCTGCAGTTcggctacagcagcaacagcaacggcaacggcaacggcaatggcaacgccgGCAGCAAtcaggcgcagcagcaacagctgcccgTGGACGATGATGAGCCGCCCAAGCTGATCATAGACgaggacgatgacgatgacttTGATGACAtcgacgaggaggaggaggaggaagaggaggaggaggatgaCTTGGAGTTAGACacagaggagcagcagcagcagcaggtggagcAGGTGGACCAAGCGCAGCCGATCGAAATTGATGCCAAAGATGAGATGCCCGAGCCGCCAGCCGCCGAGTCGGGCGAGGAgaaggcgacggcgacggcgacggcgacggcgacggctaAGGCAACGGCGAAGGCGACGGCTGGCGGCGAGCCGACGACCATGAAGACAATGATTGCCCAAGCCGAGTCGGTGGCCAAGTCCCTGAAGGAGGTGGCCAGCTCACCGTTCAAGGATGAATCTCAGGACCTGGTGCCGGTGGCCAAGCTGGTGGACAACGCCACCAGCAACCAGGTGTCGTTCAACAGCTACTTTCGGCCCAGCGACGTGGCCAACCACATGGAGCAGAGCGACGAGGAGGGCCTCGTCGCCTCCGGCAGCGCCAGCGAGAGCAACAACTCCGGCACCGAGGAcgtcaccagcagcagcagctgcagcgaacCCAAAAAGAAGTCCGCCTACAGCCTGGCCCCCAATCGGGTCAGCTGCCCCTACTGCCAGCGCATGTTCCCGTGGAGCAGCTCGCTGCGTCGCCACATCCTCACGCACACCGGGCAGAAGCCCTTCAAGTGCTCCCACTGCCCCCTGCTCTTCACCACGAAGAGCAACTGCGACCGGCATCTGCTGCGCAAGCACGGCAACGTCGAGTCCGCCATGTCGGTGTACGTGCCCACCGAGGACGTCAGCGAGCCGATACCCGTGCCCAAGTCCGTCGAGGAGATCGAGCTGGAGGAGCAGCGGCGCCGCAAGGCGGCCGAAAAGGAGCGCCAGCTGGAGCGGGAGCTGGAGCGGGAGCGCGAACGCGAGCGCGAGCGCGAACTGGAGCGCGAGCGAGAGCGTGAGCTGCAGGAGGAGGAGAAGCGCACGAAGCTCATCCAACAGCTGACGGCAGCGGCGCTCAGCCAGCAAATGATGGCGGCGGCGCAGGcggccgccgtcgccgccgcagcagccaacagcagcggcggcagcggcagcggcagcgcagcCGTCGTCGAGGCCAACGGCAGCGAGCTGCCGTACAAGTGTCACCTGTGCGAGTACTCGTTTGGCGAGCGGATGCAGTGCCTCGACCACATCAAGCAGCAGCACGCCCAAGAGTTTGCGCTGCTCCTGGCCAAAGGCGCCATCGAAGCGGAGCCAGAGacgccagcagcgacagccgcagctgcagccgcagcagcagcagcagcagcagctagcaATGCCTCCGCTGCCGTCTCGGAGGACGAGTCCAGCACGGGACGCAGCGCCGGCAAGTATCCGGACTATAGCAACCGCAAGGTGATCTGCGCGTTCTGCGTGCGCCGCTTCTGGTCCACGGAGGACCTGCGCCGTCACATGCGCACCCACTCGGGCGAGCGGCCGTTCCAGTGCGAGATCTGCCTGCGCAAGTTCACGCTGAAGCACAGCATGCTGCGCCACATGAAGAAGCACGGCGGGCACAGCCAAAACGGCGAGCAGGGCGGCGCCTCCGACTGCTCCGACGACGAGCAGATGGCAACGCCGCCGACAACCCCAACGCCcacggccatggccatggccatgccaatgcccaacaacaacaacaacaacaacaacacttgccacaacaacaacaacaacaacaacaatgggaatgggaatggaaaTGGCAAGAGCCTGCGGCTGCCCAAGCTGCACGAGCTGCTGGACAAGGCGAACGAGTGGCGCGTGAGCCGCCTGGGCGAGCACAAGGAGAACATCGCCGAGTCCTCGACGGCCACAACGGCTGCAgccgtgggcgtggccagcggCGATTTCCTGGGCAATCTGCTGGGCATCACCGACCAGGGCATACTCAACAAGCTGCTCAGCTCGCCGGACGAGGCGGCCAAGCTGCTGGGCGTCGAGAAGTGA
Protein Sequence
MLATQQQQQQQPQQQHAATAAAAAASAVTLEDAVMERQRRDSSTSESSLEHLDLGRTPKKLSSSNGAPQPTSTPHVEATSRKRKMRQQQQMQIVYSDEEDEQQQQQQQQHQQQQQLLEQSVQRTRHKQRRSGNAVAAAASASIVLDYSVGSDASSLRKKFRLNRSSISAHNGDLSESGFVDSSALSGFLLGSSGAAQSATAAQQQQQQQQQQQGSGSSSGGSSPQGLCHSSAESGISAGDEHKKYVCPICEVVSTTTHDFTNHIRCHNYDNGDTENFTCRICSKVLSSASSLDRHVLVHTGERPFNCRYCHLTFTTNGNMHRHMRTHKQHQQQQQQTQQQQQQQQAQQQQSQQQQAQPQPQQQQLQRHQQHATSNSVAQRAESYESDASCSTDISSSSSSSSSAASNNNNNSSQANNNNNNNSSSEEPQLLLACKQQQLKTNINNNNIIVSDERALDTDGDGEGEGEGVGDGDGDGDAEGSDAVDVTQMITSTPDVATLLATSSGNSSPRTPEPEPESESGALPSCPACSDDGFQTLAALYGHLETEHADIPAKCRECEVIFATQRQLQAHSCRGLQFPPLLGASSSPLHKQEPADVDEQEQDEQQLQHQHQHDIASEAMDEEEEQRLQRVSNSERDEFFQQLYLRGKADGSSLPSPIKHEPSEQRQDLADIQSILHMTSSSCTSSFLRNFEQSVNTPCSSQYSLDGRDGEEEAQDAFTSEFRRMKLRGEFPCKLCSAVFPNLRALKGHNRVHLAAVGAAGPFRCNMCPYAVCDKAALVRHMRNHNGDRPYECAVCNYAFTTKANCERHLRNRHGKTSRDEVKRAIVYHPAEDASCEEIKPKLDLDLSEHSYRSVSPSPSATNVEASSQLKHMLLAEQPSKQQQATSQPPLKIQVKSLDQLVEKPLAPAMDLSMDVLDLSKKPQREHDLLLQQQQQQQQQQQQQQQQQQQQQQQQQLLFSPGDAAKQYLQLLHNLMMQQSSGFPALFGLMPPPPAAALEKSAAAIAAPATAAAVAAVPPPLGLPLAGLGVPVPVPVPPAGPVKMVIKNGVLMPKQKQRRYRTERPFACEHCSARFTLRSNMERHVKQQHPQFYAQRQRSGHHVMRGRAANSGAAAAAAAAAAAAAAAAALTNMHQQHPQQQQHQLQHQQQHHQQQQQHAPISEQVKYAILAQQLKARKDTDLLQQALAHGSSSVHPLLQFGYSSNSNGNGNGNGNAGSNQAQQQQLPVDDDEPPKLIIDEDDDDDFDDIDEEEEEEEEEEDDLELDTEEQQQQQVEQVDQAQPIEIDAKDEMPEPPAAESGEEKATATATATATAKATAKATAGGEPTTMKTMIAQAESVAKSLKEVASSPFKDESQDLVPVAKLVDNATSNQVSFNSYFRPSDVANHMEQSDEEGLVASGSASESNNSGTEDVTSSSSCSEPKKKSAYSLAPNRVSCPYCQRMFPWSSSLRRHILTHTGQKPFKCSHCPLLFTTKSNCDRHLLRKHGNVESAMSVYVPTEDVSEPIPVPKSVEEIELEEQRRRKAAEKERQLERELERERERERERELERERERELQEEEKRTKLIQQLTAAALSQQMMAAAQAAAVAAAAANSSGGSGSGSAAVVEANGSELPYKCHLCEYSFGERMQCLDHIKQQHAQEFALLLAKGAIEAEPETPAATAAAAAAAAAAAAASNASAAVSEDESSTGRSAGKYPDYSNRKVICAFCVRRFWSTEDLRRHMRTHSGERPFQCEICLRKFTLKHSMLRHMKKHGGHSQNGEQGGASDCSDDEQMATPPTTPTPTAMAMAMPMPNNNNNNNNTCHNNNNNNNNGNGNGNGKSLRLPKLHELLDKANEWRVSRLGEHKENIAESSTATTAAAVGVASGDFLGNLLGITDQGILNKLLSSPDEAAKLLGVEK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00512904;
90% Identity
-
80% Identity
-