Basic Information

Insect: Drosophila merina
Gene Symbol: -
Assembly: GCA_035047645.1
Location: JAWNPH010000059.1:11839794-11842265[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 1.4 1.2e+02 3.6 4.5 1 23 277 299 277 299 0.92

2 11 4.5e-07 4.1e-05 24.0 0.4 1 23 305 327 305 327 0.99

3 11 1.8e-05 0.0016 19.0 4.5 1 23 333 356 333 356 0.97

4 11 0.12 11 6.9 3.8 1 20 362 381 362 384 0.95

5 11 0.0073 0.66 10.8 1.7 1 23 390 412 390 412 0.97

6 11 8.1e-05 0.0074 16.9 1.8 1 23 418 440 418 440 0.98

7 11 0.00013 0.012 16.3 3.4 1 23 448 471 448 471 0.97

8 11 0.014 1.3 9.8 0.7 2 23 478 499 477 499 0.97

9 11 0.00035 0.032 14.9 0.7 1 23 505 527 505 527 0.98

10 11 1.7e-05 0.0015 19.0 0.4 1 23 533 556 533 556 0.95

11 11 3.5e-06 0.00032 21.2 4.1 1 23 570 592 570 592 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	1.4	1.2e+02	3.6	4.5	1	23	277	299	277	299	0.92
2	11	4.5e-07	4.1e-05	24.0	0.4	1	23	305	327	305	327	0.99
3	11	1.8e-05	0.0016	19.0	4.5	1	23	333	356	333	356	0.97
4	11	0.12	11	6.9	3.8	1	20	362	381	362	384	0.95
5	11	0.0073	0.66	10.8	1.7	1	23	390	412	390	412	0.97
6	11	8.1e-05	0.0074	16.9	1.8	1	23	418	440	418	440	0.98
7	11	0.00013	0.012	16.3	3.4	1	23	448	471	448	471	0.97
8	11	0.014	1.3	9.8	0.7	2	23	478	499	477	499	0.97
9	11	0.00035	0.032	14.9	0.7	1	23	505	527	505	527	0.98
10	11	1.7e-05	0.0015	19.0	0.4	1	23	533	556	533	556	0.95
11	11	3.5e-06	0.00032	21.2	4.1	1	23	570	592	570	592	0.97

Sequence Information

Coding Sequence: ATGCCTCGAAAGGCGCGCAAAGTTGAGGCTGAGACCGAGGATCTGCAGTCCTTCCTCAACAGCATTCCCAAGGTCGGGGACAGCAACGATGAAAAGGTCATGAACAAAATAATGGAGGCcatcgaggaggaggatgcAGTACAGCATTTGATCGAAGAAGTCCAGGAGGAGGAAGATGAACAGGAACAGGATGAGGAAGAAGAAGATGAGGAGGAGTTCGATGAAGACAAATACTTCATAGACGATGAGGGCAACTGTTACATCAAGACGACGCCAAAGATCCAGAGCGAAGTCCAAAAGAAACTCAAGGAAGCGGCCAACAAAAAGGCCAAGCAAAAGCAGGCAACAAAATCGAATAGTAAACCAATTAATCTGCGTCCCGCCACTTCGCCAACGAAAAGTTCCACCAGCAAGTCCTTGCCCATCAGTGTTCGGCCAGCCCGGTCGGCGACCAAATCCTCCGCAGCACATGGCAAGCAGGAGGATCGACAACCCGCTGCGGAGTCCAACCGTGTGACTACGAGACGCAGAGCTCAACTTAATTCTAAGGCAGCCAAAGAAACCAATGACCTGGAGAGGGAGCTCGAAGAGCTGGTCGATGATCCCGACATCAATGGCGTTGTAAGCAACCTGGAGGACTATGCGGTGGAGACTTCTGTTGTGGATGCCCTCGAGAAGCTTAACCAGGACGAGGTATACGAGTTCGACGACCCAGGAGCGGAGCCTGCGGTGGAAGAAACTGACGCGAAGCAAGATTTTCTCATCACGGGCGAGCAAGTGACCCTAAAACCAGCCACAGTCCAGACGAAGGGCGACAGCGGAGCCACGTACACCTGCTCTAAGTGTCCGTATACGTCAAATAAAAGGTTCCTGATCACTCGCCACTGCCGAGGTCACGATGAGGAACCCTCCTTCAGGTGCTCCATCTGCGAACGAGCGTTCCGCACAAAGGCTGGCCTTGTGAACCACATGAACACGCACAATGGCGTTAAACCGCACAAATGCAAGTTCTGCGAAAGGTCATTCACGACGAGTGGCGAGCTGATACGGCACACGCGATACAAACACACCAAAGAGAAGCCGCACAAGTGCACCGAGTGCAACTACGCCAGCGTGGAGCTGACCAAGCTGCGCCGCCACATGACCTGTCACACGGGCGAGCGACCCTACCAATGTCCGCACTGCACCTACGCCTCCCAGGACATGTTCAAGTTAAAGCGCCATTTGGTGGTTCACACGGGCGAAAGGAAGTACCAGTGCGACATCTGCAAGTCGCGTTTCACGCAATCCAACTCCTTGAAGTCGCACAAACTGATACACACCGTGGTGGACAAGCCCTCCTACCAGTGTACTTATTGTCCCACCACGTGCGGCCGCAAGGCAGACCTTCGCATCCACATCAAGCACATGCACACGGCTGGCAAGCCGCTTAAATGTCGGCGCTGTGGTCAGGAGCTTCCCGATCGCTACCAGTACAAGCTGCACGTCAAGTCGCACGAGGGCGAGAAATGCTACCGCTGCGAGCTCTGTCCGTACGCCTCGGTGACCAAGCGTCACTTGGACTCGCACATGCTCATCCATCTGGATGAGAAGCCGTTCCCGTGCGATCTCTGCCCGCAGACCTTCCGTCAGCGGCAGTTGCTGCGGCGTCACGTCAATCTCATACACAATGATAACTACGAGCCACCGCAGCCGCGGGAAAAACTGCACAAGTGTCCGAGCTGCACGCGCACCTTCACCCACAAAGGAAATCTCATCCGGCACATGGAGCTGCACGACGACTCGGTCAATGCGCGCGAGCAAAGGAAGCGCCTCAAAATGGGCCGAGACCTGCGCATCCGTCCGGACGGAAAGCTAATAAATCTAAAAGATGAAAATTCACAAATGGACGATCAGGAGGAAGAGTGCTACGACCTGGCAGAGATCGAACCAGACGAACTGGACGAGTCCCAGTCAGAGACAGAGTCCAAGAAACCCCCGCAAAGGTCGGAACCGGTTATCATCAACAAACATGTCCGAAAATATGGCTCCAACAAGAATCCCGTCATCATTAACAAGCGACTGCGGTCGCAGAGCAACACTAATACGTTCCACATCAAGGAGGAAAAGGATAATGCCGACTTTACTGTCCAACTGCAAGCCGACGACGGGCAGATGATGGTGGTGGAGTTAATCAATGGCGCCGAGGAGGTAGTGGTCAAGAGGGAACCCAGTGGAACCACAAACATTAGTGCTTCCAACTGCTTTGGCTTTGAGGAGGATGAGGACTACGAGGAATACATAGAACAAGATAACGATGTGGAGGCCGAGTCGCAAGAGTTCCTGCAGCTCATGGACATGATAGAACAGGATGCTTAG
Protein Sequence: MPRKARKVEAETEDLQSFLNSIPKVGDSNDEKVMNKIMEAIEEEDAVQHLIEEVQEEEDEQEQDEEEEDEEEFDEDKYFIDDEGNCYIKTTPKIQSEVQKKLKEAANKKAKQKQATKSNSKPINLRPATSPTKSSTSKSLPISVRPARSATKSSAAHGKQEDRQPAAESNRVTTRRRAQLNSKAAKETNDLERELEELVDDPDINGVVSNLEDYAVETSVVDALEKLNQDEVYEFDDPGAEPAVEETDAKQDFLITGEQVTLKPATVQTKGDSGATYTCSKCPYTSNKRFLITRHCRGHDEEPSFRCSICERAFRTKAGLVNHMNTHNGVKPHKCKFCERSFTTSGELIRHTRYKHTKEKPHKCTECNYASVELTKLRRHMTCHTGERPYQCPHCTYASQDMFKLKRHLVVHTGERKYQCDICKSRFTQSNSLKSHKLIHTVVDKPSYQCTYCPTTCGRKADLRIHIKHMHTAGKPLKCRRCGQELPDRYQYKLHVKSHEGEKCYRCELCPYASVTKRHLDSHMLIHLDEKPFPCDLCPQTFRQRQLLRRHVNLIHNDNYEPPQPREKLHKCPSCTRTFTHKGNLIRHMELHDDSVNAREQRKRLKMGRDLRIRPDGKLINLKDENSQMDDQEEECYDLAEIEPDELDESQSETESKKPPQRSEPVIINKHVRKYGSNKNPVIINKRLRSQSNTNTFHIKEEKDNADFTVQLQADDGQMMVVELINGAEEVVVKREPSGTTNISASNCFGFEEDEDYEEYIEQDNDVEAESQEFLQLMDMIEQDA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00550409;
90% Identity: iTF_00504142; iTF_00615055;
80% Identity: -