Dmer002305.1
Basic Information
- Insect
- Drosophila merina
- Gene Symbol
- Sall1
- Assembly
- GCA_035047645.1
- Location
- JAWNPH010000002.1:18090472-18092714[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 13 0.0021 0.19 12.5 0.1 1 23 117 140 117 140 0.95 2 13 2.1 1.9e+02 3.0 0.2 1 23 292 314 292 314 0.91 3 13 4.6e-05 0.0042 17.7 2.7 2 23 317 338 317 338 0.97 4 13 1.8e-05 0.0016 19.0 0.2 3 23 346 366 344 366 0.98 5 13 1.5e-07 1.3e-05 25.5 4.1 2 23 373 394 372 394 0.97 6 13 1.3 1.2e+02 3.6 0.4 5 23 407 425 404 425 0.95 7 13 0.35 32 5.5 5.4 3 23 432 453 430 453 0.93 8 13 0.0089 0.81 10.5 0.2 2 23 464 484 463 484 0.96 9 13 4.6e-06 0.00042 20.8 0.6 1 19 490 508 490 512 0.95 10 13 8.9e-06 0.00081 19.9 0.4 1 23 520 542 520 542 0.98 11 13 2.6e-05 0.0024 18.4 7.6 1 23 548 570 548 571 0.96 12 13 0.00012 0.011 16.4 6.6 1 23 576 598 576 598 0.98 13 13 0.00068 0.062 14.0 6.1 1 23 604 626 604 627 0.96
Sequence Information
- Coding Sequence
- ATGGTCATGCCCGGTGACGTGGAGCTGGGTGTAAGCCCGAATTTGATCCTTAAAACGCCGGCGTGTGCCACTCGGAAGATTGCCTCTTTGTCTCGGGATCATACTCAAAGATCCAGGACTCGTCACCTTTTCGATTTTAATGCGCTTGACGATGAGGCCTCATCCAGCTCTAGGAAGAGCCATCTACTGGATGATGCGCCTACGGCGGGCATCGCACCTTCCAACTGCACTTCCACATCTTCGGCTTTGCTGGCAGGTCCACCAATAGCCTCCACTTCCCGGGCTGCTGCCGAGGCAGAAGCCGCTGCCATGGCAGTCGCCCAAAGAAAGCAGAATCGTCGTAAGCTCTACAAATGCCCCAATTGCGACGCTATCTTCGAGAAGTTAAAGGACCGGAATGCACACATGATTGGAGAGCATAACTATGTCCGTCAGAACCGCAGGCTCATTTGCACCCAGGTGCCCGGTTCCGAGATGCTCCCACCGCAGCAGCAAACAATGATCATACCGCCAGCCGAGGGGGTCGCCCTCCAAGAGGACTCCAAAGACGGAATTGTGAAAATCAAGCAAGAACAATGCCAAGACAAGACGGAGGTAGATCAAATGCACTCCAATTCCGAGCTGTTGACAGATGTCAAGGACTCGGAACTGCTCGGAATCGGGGATGCCGATGGGGACGAGGAGGGTGAAGCCGATTTCAAACCACCTAGTCAACTGGATGAGAAGATCGTATTACCACCGCTGGCCATGACGACTCCAGCTGCTAAGCTAGCAGCGCTTTATCGCATGCTTATCGCCTACAATGAGTCCAAGCTGGGCCAAGAGCGAAACAACCTAAGCGAGCTGGAACAGAAGGCCATGGAAAAGTCAATCTTTCTCTGCTATGTCTGCCGAACCGACTTCCCATCGGTGAAGCTGTACGATGCTCATCTTACCGAGCATCCGGCCGAATGCTTTACCTGCGGCAAGAAGTTCTATCGCTGGAAGAACTTTTCCCTCCACCTGAAACGTCATCTCGGTTGGAAGGAATTTGGCTGCTATGTTTGCGATAAGAAATTCGTTGTACGCAGCGCCCTGGTCGAGCACATGCGGATGCATACGGGCCAAACGCCACTCAAGTGTAAGATATGCGGCAAGAAGTTTAAACGGTACTCGAATCTAACACAGCACCGAAAAAGGCACACCAAGATGATACTGCGCAAGAAGGAGTATGTGTGCCACTGCGGCGAAGTGCTGCCCTCAAAGGCACGATTCCTGTGGCACAAGGAGACCCACGATCTAAAGCCAAAGTGCTGTCCATATTGCTGCGATCGATTTGTGCATGCTAATTCGCTACGACGCCACATCCGGCTGGCACACTCGGAGAAATTCGATTATTCCGAGCCCATAGAGTGCCCAATGTGCAAGCAGACCTTTGCCAAAACCTCGATTAAAGCCCACATGGCGACGCATTCGACGGATCCGCAGTACGACTGCACCATCTGCAACAAGAGCTTCTCCACCAAGTGGAACCTCAAGATCCACTCATGGGTGCATGCCAATCGCACGGCCAAACCTTTCAAGTGCGAGTACTGCCCGAAGGCGTTTGTGCGCGAGCTGGACTTCAAGAACCACATCAACGCGCACAAGCAGATCAAACCGTACACGTGCGAGTACTGCGGCTGTAAGTTCATCCGCAAGTACAACTACATGCGACATCGTCGCGAGCACCACGGAACGAAGAAGTTTACATGCGACCAGTGCGACAAAACCTTCCACCGGCACTACTATCTCGTTGAGCACCGGCGCATGCATACCGGCGAGCGACCCTTCACCTGCACCATATGTGGCAAGAGCTCCACCACCAAGACCAACCACAACAAGCATCTGAAGATCCACCACTCGCGCGATCCCTTTACTGTCGAGGTTTAA
- Protein Sequence
- MVMPGDVELGVSPNLILKTPACATRKIASLSRDHTQRSRTRHLFDFNALDDEASSSSRKSHLLDDAPTAGIAPSNCTSTSSALLAGPPIASTSRAAAEAEAAAMAVAQRKQNRRKLYKCPNCDAIFEKLKDRNAHMIGEHNYVRQNRRLICTQVPGSEMLPPQQQTMIIPPAEGVALQEDSKDGIVKIKQEQCQDKTEVDQMHSNSELLTDVKDSELLGIGDADGDEEGEADFKPPSQLDEKIVLPPLAMTTPAAKLAALYRMLIAYNESKLGQERNNLSELEQKAMEKSIFLCYVCRTDFPSVKLYDAHLTEHPAECFTCGKKFYRWKNFSLHLKRHLGWKEFGCYVCDKKFVVRSALVEHMRMHTGQTPLKCKICGKKFKRYSNLTQHRKRHTKMILRKKEYVCHCGEVLPSKARFLWHKETHDLKPKCCPYCCDRFVHANSLRRHIRLAHSEKFDYSEPIECPMCKQTFAKTSIKAHMATHSTDPQYDCTICNKSFSTKWNLKIHSWVHANRTAKPFKCEYCPKAFVRELDFKNHINAHKQIKPYTCEYCGCKFIRKYNYMRHRREHHGTKKFTCDQCDKTFHRHYYLVEHRRMHTGERPFTCTICGKSSTTKTNHNKHLKIHHSRDPFTVEV
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00483112; iTF_00613629;
- 90% Identity
- -
- 80% Identity
- -