Basic Information

Insect: Drosophila meridionalis
Gene Symbol: ush
Assembly: GCA_035045145.1
Location: JAWNPG010000054.1:8613741-8619134[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.0069 0.48 11.1 0.0 1 20 198 217 198 219 0.90

2 9 0.0003 0.021 15.4 0.8 1 23 276 298 276 298 0.98

3 9 0.053 3.7 8.3 1.0 2 21 344 363 344 364 0.92

4 9 0.051 3.6 8.3 2.9 2 21 748 767 747 768 0.93

5 9 0.0095 0.67 10.6 0.0 3 21 816 834 814 835 0.91

6 9 0.0068 0.48 11.1 0.0 2 23 894 915 893 915 0.98

7 9 0.004 0.28 11.8 1.3 1 23 921 943 921 943 0.99

8 9 0.0014 0.099 13.2 1.9 1 23 1002 1025 1002 1025 0.96

9 9 0.32 22 5.8 0.7 2 20 1133 1151 1132 1153 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.0069	0.48	11.1	0.0	1	20	198	217	198	219	0.90
2	9	0.0003	0.021	15.4	0.8	1	23	276	298	276	298	0.98
3	9	0.053	3.7	8.3	1.0	2	21	344	363	344	364	0.92
4	9	0.051	3.6	8.3	2.9	2	21	748	767	747	768	0.93
5	9	0.0095	0.67	10.6	0.0	3	21	816	834	814	835	0.91
6	9	0.0068	0.48	11.1	0.0	2	23	894	915	893	915	0.98
7	9	0.004	0.28	11.8	1.3	1	23	921	943	921	943	0.99
8	9	0.0014	0.099	13.2	1.9	1	23	1002	1025	1002	1025	0.96
9	9	0.32	22	5.8	0.7	2	20	1133	1151	1132	1153	0.91

Sequence Information

Coding Sequence: ATGGTCCTCGACTTCGCCTTCGACTTGGACTCGGACTTGGTCGACAACCTCGATTCCAAAGATTTGGGCGCACATGAGCTGAGCgaggagaagcagcagcaacagctggaCGAGCAGCCCGAGGACGAGCAGCTGGATCAAATGGAGCAGCAAGCTAGCAACGCCTCTGAGCAGCTCGAGGAGACCGACATGGATCAGGAAATGGTCAAGGAGGAGCAGGCAGCGGCCCAGGAGGCCAGTGCGCAACAGCAGAATGTGGCCGACAGCTCGACGACTCCGCCGCGCAGTCCCACGCCGCCCGAGCTGGTGCCGAAGCTGGAGCGTGCCGACTCGCCGGCGACACCGCCTTCTGTAGCCGCCACGCCCAGTCCGCCGCCTACGCCTACGCCACCATTGGTGTTGCCCAAGCTGCGGCTCAATGCTTTGCTCGCCTCCGATCCGGCTCTGAAACCCGATGCCAAGGAGCTCAATCTCGAGCCACGCCTGCTCGGTCCGCCGCCGCAGCTGATAAAGcccgagcagcaacagcagcagcagcagagtttGCCCGATCCGAATAGTCTGGTGGAGCCGCTGCTCAAGCCGGCGCGCTTTATGTGCCTGCCCTGCGGCATAGCCTTCAGCTCGCCCTCGACGCTGGAGGCGCACCAGGCCTACTACTGCTCGCATCGCAACAAGGATGCGGACGAGGAGTCGGCTGGCGGCGACAAGGCAGCAGCCGGCGCTGGTGGCGGCGCCAATCCGAATGCCAACAGCAGCTCCagtggctccggctccggttCCGGTTCGGAGCCACCCGCCAAGGTGGCGCGCACGGGCAAGCAATACGCCTGCACGCAGTGCTCCTACAGCGCCGACAAGAAGGTCTCCCTCAACCGGCACATGCGCATGCATCAGACCTCGCCCGCCGCGCCCACCCTCAACAGCCTCTCCGGGCTGGCTGCCAACGgcgtggctgccgctgccgccgccgccgccgctgctgcggccAACGCGCTCGAGGAGAGCCCTAGTCAACAAATCGATCGCTACTGCAGCGACTGTGATATCCGCTTCAACAACATCAAGACCTACCGCGCCCACAAGCAGCACTACTGCAGCTCCCGGCGCAGCGATGGCCAGCTGACGCCCAAGGCCGAGGCGAAcgttaacagcagcaacagcggagGCACTGCAGCGGgcgttgctgcagcagcggctgcagccgcagcgggCAAGCACAGCGGCGCTCACAGTCCGCAGACGCGCAACAAGACACCGACACCAGCAATGgtcgctgctgcggcggctgcggcggccgctgctgctgctgccgcctcgCTGCAGGTGGCACCGCCGCAGCCCTTCCTGGCACTGCCCACCAATCCTATCATCATAGTGCCCTGCTCGCTGATACGCGCCGCCAGCCTCATACCCGGACCACTCACCACCTCTACATCCGGCATTGTCAATCCGGAGTCCACATGCTTCACCCTGGACAATGGCGCCCTCAAGCCACTGGCCACCGCACTCAATATCAATGCGTTGGCGggcaatgccacgcccacgccaacAGGCACGTCCATGCCTAGCAGCAATCAGCTAAGCATGCCCGCCGTGGAGCCAGAGCGGCCCAGCGCAAGCAGCGTCCTGGAGACGGAGTCCAAGAGCAGTCCGCCAGAGCCCAAGCGAAAGGAAGCGGGCGGCATGCGCGACACCACGCCCCTAGATCTGTCGCTACGTCGCTCGCCCATttcgccgctgctgcagcgccagcgTCTGATGGAGGAGGCGCTGCTCAGCGCCGGCAAGGAGAACATGGAGAGCACTGGCCGAACAACTGGCAGCGTCACTCCCGAGCAGATCGTGTGCGCGCCTTCGCTGCCCAGCAGCCCTTCGATGAGTCCCTCGCCCAAGCGCCGTACGATCAGTCCGCGCAGCTCGGGCGCGGGCAGCGCTGCCTCCATGTCACCCCCAGCGCTGGCAGTGCCGCATCTGCTGGACAATCTGCAGCCATTGCGGTCCATGTTGCCGGCCGACTTTGCGCTATCCGAATCGCTGCTGGCCAAGACCAATCCGGAGCTGGCGCTCAAGctggcagcagccgctgcagcagccgtggcgggcagcagcagcgccgagCTGGCCAGCAAGCTGTGCTTCAGCCCAGGAACGGGCGCTGCTCCTCCTGCGGCTGTGGCCAGCGTTGCCCCCACTGCGCCCAGCAACCAGCCGCAGATCTATGTGAAGCAGGGCGTGTCCAAGTGCAAAGAGTGCAACATAGTCTTCTGCAAGTACGAGAACTACCTGGCCCACAAGCAGCACTACTGCTCCGCTCGCAACCAGGACACGGGTGTGGATGGTGACTCCAAGAGTGCTGTGACGCCGCCCGCCGTAGCTGGACCCGGTGTAGCCGCTGGCGCCTCCTCGTTGGAGAACTCGCCCGTGGCCTATCAGCAGCTGATATGCGCCGCCTGCGGCATCAAGTACACCTCGCTGGACAATCTGCGCGCCCATCAGAACTACTACTGTCCCAAGGGTGGGGCGGCTGCCACGCCCGCCGAGGCAGCCACTccacagctgccgctgcccaagGAGAAGTGCGTCAAGTGCAAAACGCTGCACGAGCACGGCCAGCCCTGTCCTACGCCCCCGGTCACGCCCCAGCTGGCGCCGGCCAGCGTCGCGAACAGCGTGAACAAGTGTCCCGTCTGCGGTGTGGTCAGCCCCACCGCTGCACTGGCTCGCAAGCACATGGAAATGCACGGCACGGTCAAGGCGTTCCGCTGCAGCATCTGCCAGTACAAGGGCAACACGCTGCGCGGCATGCGCACCCACATCCGCACCCACTTCGACAAGAAGACCAGCGACGTCAACGAGGAGCACTACATGACCTGCATCTTCGAGGAGGATgcggcggtggcagcggcaacggtGACGGCGCCTCTGCCTCCAGCCATGGGCCTGGAGCTGCCCGCTGTGACATCGGCccaggagcagctggagcagcatgCGGCACAGATCTTCAACTGCGATCACTGTAACTATGCATCCACCTACAAGGGCAATGTGTTGCGCCACATGAAGCTATTGCATCCACACGTGGCAATCAGCTCGCCCTCCATATCACCCGAGTCCCGTGAACAGGATGCAAATGCCCATGCCCTGCCCGAAGCAACTCTGGTAAATGGCGAACGCGAGGCGGCCAGTTTCCACATCAAGTCGGAGCCGTTGGAACCACCTGTGGCCACGTTGAGCCTGGTGCACGAGAACAACAATTCGCCCATTGGCACGCCGCATACGCACATCAAGGCCGAGCCGCTGGACATGGGCATTGAGCTGGGCCCAACCACACTGCCACCACCGGCCATGGCCAACTCGCCGCTGGGGCCGAGCGCCGCGGAGGCTATGAAGAAATACTGTTCCACCTGCGACATATCGTTCAACTATGTGAAGACCTTTTTGGCGCACAAGCAGTTCTACTGCAAGAGCAAGCTGCATCGGCCAGAGGCCAGCGATAGCCCCAGTCCCACTGTGGGCATCGGTGGCGCCGCCATGCCGCTGCAGTCGCCCAgcgagctgctgttgctgcagaaGAACAAGGAGAATCTGCAGGAGGCGGCCATTTGA
Protein Sequence: MVLDFAFDLDSDLVDNLDSKDLGAHELSEEKQQQQLDEQPEDEQLDQMEQQASNASEQLEETDMDQEMVKEEQAAAQEASAQQQNVADSSTTPPRSPTPPELVPKLERADSPATPPSVAATPSPPPTPTPPLVLPKLRLNALLASDPALKPDAKELNLEPRLLGPPPQLIKPEQQQQQQQSLPDPNSLVEPLLKPARFMCLPCGIAFSSPSTLEAHQAYYCSHRNKDADEESAGGDKAAAGAGGGANPNANSSSSGSGSGSGSEPPAKVARTGKQYACTQCSYSADKKVSLNRHMRMHQTSPAAPTLNSLSGLAANGVAAAAAAAAAAAANALEESPSQQIDRYCSDCDIRFNNIKTYRAHKQHYCSSRRSDGQLTPKAEANVNSSNSGGTAAGVAAAAAAAAAGKHSGAHSPQTRNKTPTPAMVAAAAAAAAAAAAAASLQVAPPQPFLALPTNPIIIVPCSLIRAASLIPGPLTTSTSGIVNPESTCFTLDNGALKPLATALNINALAGNATPTPTGTSMPSSNQLSMPAVEPERPSASSVLETESKSSPPEPKRKEAGGMRDTTPLDLSLRRSPISPLLQRQRLMEEALLSAGKENMESTGRTTGSVTPEQIVCAPSLPSSPSMSPSPKRRTISPRSSGAGSAASMSPPALAVPHLLDNLQPLRSMLPADFALSESLLAKTNPELALKLAAAAAAAVAGSSSAELASKLCFSPGTGAAPPAAVASVAPTAPSNQPQIYVKQGVSKCKECNIVFCKYENYLAHKQHYCSARNQDTGVDGDSKSAVTPPAVAGPGVAAGASSLENSPVAYQQLICAACGIKYTSLDNLRAHQNYYCPKGGAAATPAEAATPQLPLPKEKCVKCKTLHEHGQPCPTPPVTPQLAPASVANSVNKCPVCGVVSPTAALARKHMEMHGTVKAFRCSICQYKGNTLRGMRTHIRTHFDKKTSDVNEEHYMTCIFEEDAAVAAATVTAPLPPAMGLELPAVTSAQEQLEQHAAQIFNCDHCNYASTYKGNVLRHMKLLHPHVAISSPSISPESREQDANAHALPEATLVNGEREAASFHIKSEPLEPPVATLSLVHENNNSPIGTPHTHIKAEPLDMGIELGPTTLPPPAMANSPLGPSAAEAMKKYCSTCDISFNYVKTFLAHKQFYCKSKLHRPEASDSPSPTVGIGGAAMPLQSPSELLLLQKNKENLQEAAI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00598429;
90% Identity: iTF_00532635;
80% Identity: -