Basic Information

Gene Symbol
-
Assembly
GCA_035045145.1
Location
JAWNPG010000020.1:670929-675572[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 25 0.0013 0.092 13.3 1.4 1 23 221 243 221 243 0.97
2 25 0.013 0.92 10.2 2.0 1 23 249 271 249 271 0.97
3 25 0.032 2.3 9.0 0.5 2 20 303 321 303 331 0.96
4 25 0.019 1.3 9.7 0.9 1 23 400 423 400 423 0.93
5 25 1.1 79 4.1 3.1 2 23 434 457 433 457 0.93
6 25 1.2 82 4.1 0.6 3 23 499 519 498 519 0.97
7 25 0.088 6.2 7.6 1.2 1 23 599 622 599 622 0.95
8 25 0.00066 0.046 14.3 0.1 1 22 631 652 631 652 0.96
9 25 0.24 17 6.2 2.4 1 23 661 684 661 684 0.94
10 25 0.0011 0.078 13.6 0.2 2 23 716 737 715 737 0.97
11 25 2.2e-05 0.0015 18.9 5.9 1 23 745 767 745 767 0.99
12 25 0.024 1.7 9.4 1.2 1 23 915 938 915 938 0.92
13 25 0.031 2.2 9.0 0.4 2 22 946 966 946 966 0.95
14 25 1.1 80 4.1 0.6 1 23 975 998 975 998 0.87
15 25 1.1e-05 0.00079 19.8 1.9 1 23 1023 1045 1023 1045 0.97
16 25 0.00014 0.01 16.3 0.9 1 23 1052 1074 1052 1074 0.98
17 25 1.5 1e+02 3.7 0.2 2 21 1101 1120 1100 1121 0.87
18 25 0.014 0.96 10.1 4.3 1 23 1166 1189 1166 1189 0.96
19 25 0.039 2.7 8.7 0.9 1 23 1226 1249 1226 1249 0.90
20 25 0.015 1 10.0 3.1 1 23 1277 1300 1277 1300 0.97
21 25 1.4e-05 0.001 19.5 0.1 2 23 1328 1349 1327 1349 0.95
22 25 4.8e-05 0.0034 17.8 2.9 1 23 1355 1377 1355 1377 0.99
23 25 2.4e-06 0.00017 22.0 2.0 1 23 1383 1405 1383 1405 0.97
24 25 6e-08 4.2e-06 27.0 2.4 1 23 1411 1433 1411 1433 0.99
25 25 0.00018 0.013 16.0 0.5 1 23 1439 1461 1439 1461 0.97

Sequence Information

Coding Sequence
ATGTTGCCGACAAATATTTGCCGTACATGCACTCTGCATAATGATAGCTTACTTCCGCTTGCCACACCCACtgataaatatgcaaataaaagtttaaatgaTATGTTACTCGAATTGACACAAAATGATCCCCTGCAGGAGCATGCGGATGAAAGTCTGCCGCAGCACTTGTGTATTTGCTGCTTGCACAAATTGGAAGCTGCGTATGCGTTTGTATTGCAGGCGCGCCAGGCTCAAGAGCAGCTGTTGTCGCAGCTGCGCAAGGGCTTGCAGACACAGTGCTTGGATGAGATGCCCATAGACATTAACTTGCAGCACATCAAAACCGAAACGATCGTTGACATGCAATTAACTAGCAAAACCAAAAGTGAAGAAGATGAGACGAAGGCTGAAGAGAGGGAGCACGAGATTACCGCAGTGTCTATTCCAGACCTGAAGTGGCAGCCAGACAGCAATAGTGAGAGCAATCAGACTGCTATTGATGACCAGGACGCGGACTTTAAGCCAAAGCAGTTGCGGCGCAGCGCACgtaaagccaaagccagcaCAGACAGCGAAAATGAAGAAACATCTGCACATACGAATCCCATGCCTGTCAAACGTCGCCGTGGTCGCCCAGCACGTTCACTCACAAAGGAGACAATCAACGAAACGGGGCGGCATGTGTGTGAGGTTTGTGGAAAAACTTTTTCGTGGTACCGCGATATGCAACGCCATTCGCGCATACACTTCGAGCAAGCGACCTTTGTGTGTGACAACTGTGGCAAGAGCTTCCTGCGCAAAGACAAGTACATGTTTCATCTGCGATCGCACGAGAAGCGTGCAGCCAAGAGTCACGCCATGCAGCTGAGCAGCGAATGGCGCTTCGCTGAACGCCTGTACAACTCTGGCCGGCTCAAACGTGCGGAGTGCAAGTTGTGTGGCGTAAAATACCAGCGTCTAGGGGATCTGCGCGAGCATATGGCCTGCCACAAGAGCATAGAGACTTTGTCCGAACTGAGTCTAGAGAGTGATGTTATCAGAGAACAGTTTGccaaagagcagcagcagttagaCTTGTCGCTGATAAAGCAACAGGTGTGCGCAGAAATTGCCAGTGGACGAGGTCAGCTGGACAAATACTGCGCTGTGGTCAACGCGTACGGTTATGAGCTCTGTCTTAGTGACTCAGACGAAGATGTAGCTGACCGACCTAAATACCAGTGTCTGCCGTGCAACATCAACTTCACGCGCAAATATCGTCTTATGCGACACACACTGGAGGAGCATACACAGGCAGATACAACAGTGTCTTGGCAACGCTGTGACGTGTGTCAAATTGGTTTTGTGTGTGCGAAAATGTTAGAGCAACATCAGCGCACGCAATGCCACAGTAAACTGAAGCGTTACAGTTGTCCAAACTGCCCAGGTAAATTTCTGTGGCTACAGAACCTGGAGCAGCATGCGTGCTTCCAACGTGGCAAGCAGCACGAggagcaacggcagcaaaaGCTGTGTTGTCTCTGTGATATCCAACTGAACAGCATGTTCGAATTGCGCGCCCATTTGCTAATCCATCAAGATGGACGCACTGGCATATATCCAGAGCAGCAGGCGACCTTCTTTCGCACATACTATCCCAATGGTCTTGACTGCAGCGTGTCTGAGCTGAGCGCACGCATTACCACCGATTTCAAGGCGGAGGATTATGGGCGATACTTTAATGCCAGAACGAGAAACGGTGAGGAGCTCGATTTCTTCGCCTCGGACTCTGATATGAGTGATACGGACGCGCAGAGCTCTGACGGGACGCTTCACATATGTTCCTTGTGTGGAGTGACGAAAAGGCGCCTGAGTCAATTGCTCGAGCATCAGCAAAGCCAGCATTGTGAGGCAGAAGAAAGGCTGCCATATGTCTGTGATGACTGCGATTTGGGCTTTGTAGCCAACTCGCTGCTCCAACAGCATCGCCGAAGGGTCTGTGCCAAGCAGCATACCAAGTACGACTGCCAGCAATGCAATCAGAGGTTTTACTGGCTTTCCAATTACGAGTTGCATATGCATTTGCAGCACGAGACTCAAGCCGAGCTGCAGATGGATGTTGTCAATCAACAGGAGCAAGATTCAAGTACGAGAAACAAGCGTCAGTCTACGGCGGCCAAGTTGCAGTGCGGCGAGTGCGAAAAGGTGTTCATCTGGCCAAAGGATCTGACGAGGCACAAGCGCCTACACCAGCCACAAGCTTTGGCACAGTTCCAATGCTTGCACTGTGATCGCAAGTTCCATCGCAAGGATGGGCTCAAATCCCATATGCGCGTGCATGGCGAACAGCAGGCAGAAGCGTCGGCTGCCAGTGAACAAGTTCCATCCATGCTGCAGCGCATGCCAGTGGTGCTCACCCAACTGTGTCGACCCAATGGCTGCAAGCAAATTCAATGCATGATCTGTCTCTCGCAGCACTCAAAAATCTCTGATCTTCGCACACATCTGCTTAATCATCAGTATTCGGTGAAATTTGGAGAGGAGCGGGGCCAACGCGAGAGCATAGAGGGCATTTCACGTTCTCTATATCCAGAACTAACTGCACcattggagcagcagcaattaaTCGAACGCATTCAAAGTGATGTGACAAAAGGCGTGGAGCTGGAAAGATTCGTATCCATTACCAACGAGGCGGGCATTGAGCTCAGTCTGGACAGCAGTGAGACGGAAACCGATTCGGACTCTGCCGAGGCAGTCAAAAGCAATAGCGGACAACAATATAGCTGTGAGCTCTGCCAGTTGAAGGTATCGCGCAAGCATCAGCTCTACGCCCATGAGCTGGAGCAGCACTCGTGGCAGGAGGCGACCCGTGTTTGCAGCTATTGCCAGGCGAGATTCGTAAATGAGCAGCTACTAGATCATCACTATCGGACGCTCTGTCGCAACGTGCACCGACGCTATTTTTGTCGTAAATGTCCACTACGTTTCCGCTGGCGCGAGAATATGAAGCTGCACTCTGACGTGGCGCACAACGAAGGCAGAGCTGAGAAATCGAACTTGGGCATTAAGTTGAACGGATCGCCCCTGTTGCCCGTCGTTAGTTATGACTGCACCGAATGCAATCGTagctttaaaatgcaaaaggaTCTCACCAGGCACACTCTGATGCACGCCCAGGAGTCAAGCATTTATCGTTGTCGTTGGTGTGCACGACGATTCTACCGCCAGGCCAATCTGCTGCAGCACATTGAGCGTCACGGCATTAGCGCCGAACAGCTGCCCTATGCTGAGGCTCTGCTCAATGTCAGCCGCCACCCGCATGGTCAGAAGTGTATCCAGTGCAAGGTGTGCAACGTGACCTATCCCACCattgctgcgctgcgctgtcaTCTGCAATCAGCGCCAGCAGGCACCCATCATGAGTATGGCTCGTTGCTCAATTACTCCATTACCAATCAGTTGGGCTACGAGCTGCATCTGGAGGACTCGGAAACGGATGAGGAGGCTAAGCCGCCAGGCACGCCAACGCACTATACCTGCAGCATATGCCAACTGCGCTGTGTGCGCAAGTTTGAGCTGCACCAGCATCAGCAAGCGATGCATCGAGTGGAACGCATAACTGAAGGTTGCGATGTCTGCATCTTTAAGAGTGTCTCGGCAGATCTTATTGCCTATCATCAACGCGTCTTGTGCAATAATGCGGAGAAACACTTCAAGTGCTCCAAGTGTGGCTACAAGTTTATGTGGGAAAAGAATTTGTTGCAGCATGTGGAGCTGCAGCATCCCAGCAGCGAAAGTAGCGGAACGCAACCGTGTGCGAGTGCTCTGGCTGCGCAGGAGGCAACCAGTGCAGAGTGCCAGATATTCCAGTGCGGCCAGTGTCCTAGTAAATATAATCGCAAGGATCGCCTCACTGCCCACGTAAAGAAATGTCATACAGTAGGAGCAAGTGGCGCCACGGCTGCGGGAACGAAGCTTATGAAAAATTCAACTGGCGGCAAGCAGCAGAAAAGTTTTCTGTGCGCTTTCTGCGGCAAGGCGGTTAGCTCCTCTTCTAATCTGATCATACACATACGTCGCCATACTGGCGAGAAGCCTTTTAAGTGTGACTACTGCGACATGGCATTTCCACGTTCCTCCGATCTGCAGTGCCATCGACGCACCCACACGGGCGAGCGGCCGCATGTCTGCACCGTTTGCCAGAAGGGCTTTGCCCGATCCTACAAGCTGCAGCAACACATGCGCATCCACAATGGCGAACGACCATATAAGTGTACTTATTGTGACAAGAGTTTTACTCAGTCGAATGATCTGACTCTTCACATACGGCGACACACAGGCGAGCGTCCCTATCAGTGCAATACGTGTGGCGAGCGTTTCATTCAGGGCACAGCTCTGAAAAATCATCGCCTTCAACATGGACACCATGATACGGAAGTGGACCAGGTCAAGGATAATTAA
Protein Sequence
MLPTNICRTCTLHNDSLLPLATPTDKYANKSLNDMLLELTQNDPLQEHADESLPQHLCICCLHKLEAAYAFVLQARQAQEQLLSQLRKGLQTQCLDEMPIDINLQHIKTETIVDMQLTSKTKSEEDETKAEEREHEITAVSIPDLKWQPDSNSESNQTAIDDQDADFKPKQLRRSARKAKASTDSENEETSAHTNPMPVKRRRGRPARSLTKETINETGRHVCEVCGKTFSWYRDMQRHSRIHFEQATFVCDNCGKSFLRKDKYMFHLRSHEKRAAKSHAMQLSSEWRFAERLYNSGRLKRAECKLCGVKYQRLGDLREHMACHKSIETLSELSLESDVIREQFAKEQQQLDLSLIKQQVCAEIASGRGQLDKYCAVVNAYGYELCLSDSDEDVADRPKYQCLPCNINFTRKYRLMRHTLEEHTQADTTVSWQRCDVCQIGFVCAKMLEQHQRTQCHSKLKRYSCPNCPGKFLWLQNLEQHACFQRGKQHEEQRQQKLCCLCDIQLNSMFELRAHLLIHQDGRTGIYPEQQATFFRTYYPNGLDCSVSELSARITTDFKAEDYGRYFNARTRNGEELDFFASDSDMSDTDAQSSDGTLHICSLCGVTKRRLSQLLEHQQSQHCEAEERLPYVCDDCDLGFVANSLLQQHRRRVCAKQHTKYDCQQCNQRFYWLSNYELHMHLQHETQAELQMDVVNQQEQDSSTRNKRQSTAAKLQCGECEKVFIWPKDLTRHKRLHQPQALAQFQCLHCDRKFHRKDGLKSHMRVHGEQQAEASAASEQVPSMLQRMPVVLTQLCRPNGCKQIQCMICLSQHSKISDLRTHLLNHQYSVKFGEERGQRESIEGISRSLYPELTAPLEQQQLIERIQSDVTKGVELERFVSITNEAGIELSLDSSETETDSDSAEAVKSNSGQQYSCELCQLKVSRKHQLYAHELEQHSWQEATRVCSYCQARFVNEQLLDHHYRTLCRNVHRRYFCRKCPLRFRWRENMKLHSDVAHNEGRAEKSNLGIKLNGSPLLPVVSYDCTECNRSFKMQKDLTRHTLMHAQESSIYRCRWCARRFYRQANLLQHIERHGISAEQLPYAEALLNVSRHPHGQKCIQCKVCNVTYPTIAALRCHLQSAPAGTHHEYGSLLNYSITNQLGYELHLEDSETDEEAKPPGTPTHYTCSICQLRCVRKFELHQHQQAMHRVERITEGCDVCIFKSVSADLIAYHQRVLCNNAEKHFKCSKCGYKFMWEKNLLQHVELQHPSSESSGTQPCASALAAQEATSAECQIFQCGQCPSKYNRKDRLTAHVKKCHTVGASGATAAGTKLMKNSTGGKQQKSFLCAFCGKAVSSSSNLIIHIRRHTGEKPFKCDYCDMAFPRSSDLQCHRRTHTGERPHVCTVCQKGFARSYKLQQHMRIHNGERPYKCTYCDKSFTQSNDLTLHIRRHTGERPYQCNTCGERFIQGTALKNHRLQHGHHDTEVDQVKDN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00509945;
90% Identity
iTF_00544627;
80% Identity
-