Basic Information

Insect: Drosophila meridiana
Gene Symbol: -
Assembly: GCA_035045185.1
Location: JAWNPF010000055.1:16056857-16061491[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 25 0.0013 0.097 13.3 1.4 1 23 222 244 222 244 0.97

2 25 0.046 3.5 8.5 2.0 1 23 250 272 250 272 0.97

3 25 0.16 12 6.8 0.7 2 20 304 322 304 325 0.95

4 25 0.019 1.4 9.7 0.9 1 23 401 424 401 424 0.93

5 25 1.1 83 4.1 3.1 2 23 435 458 434 458 0.93

6 25 0.17 13 6.6 0.9 2 23 499 520 498 520 0.97

7 25 0.087 6.5 7.6 1.2 1 23 600 623 600 623 0.95

8 25 0.00065 0.049 14.3 0.1 1 22 632 653 632 653 0.96

9 25 0.24 18 6.2 2.4 1 23 662 685 662 685 0.94

10 25 0.0011 0.082 13.6 0.2 2 23 717 738 716 738 0.97

11 25 2.2e-05 0.0016 18.9 5.9 1 23 746 768 746 768 0.99

12 25 0.023 1.8 9.4 1.2 1 23 916 939 916 939 0.92

13 25 0.03 2.3 9.0 0.4 2 22 947 967 947 967 0.95

14 25 1.6 1.2e+02 3.6 0.6 1 23 976 999 976 999 0.86

15 25 1.1e-05 0.00084 19.8 1.9 1 23 1024 1046 1024 1046 0.97

16 25 0.00014 0.011 16.4 0.9 1 23 1053 1075 1053 1075 0.98

17 25 1.5 1.1e+02 3.7 0.2 2 21 1102 1121 1101 1122 0.87

18 25 0.015 1.2 10.0 3.6 1 23 1167 1190 1167 1190 0.96

19 25 0.042 3.2 8.6 0.7 1 23 1227 1250 1227 1250 0.90

20 25 0.015 1.1 10.0 3.1 1 23 1278 1301 1278 1301 0.97

21 25 1.4e-05 0.0011 19.5 0.1 2 23 1325 1346 1324 1346 0.95

22 25 4.8e-05 0.0036 17.8 2.9 1 23 1352 1374 1352 1374 0.99

23 25 2.3e-06 0.00018 22.0 2.0 1 23 1380 1402 1380 1402 0.97

24 25 6e-08 4.5e-06 27.0 2.4 1 23 1408 1430 1408 1430 0.99

25 25 0.00018 0.014 16.0 0.5 1 23 1436 1458 1436 1458 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	25	0.0013	0.097	13.3	1.4	1	23	222	244	222	244	0.97
2	25	0.046	3.5	8.5	2.0	1	23	250	272	250	272	0.97
3	25	0.16	12	6.8	0.7	2	20	304	322	304	325	0.95
4	25	0.019	1.4	9.7	0.9	1	23	401	424	401	424	0.93
5	25	1.1	83	4.1	3.1	2	23	435	458	434	458	0.93
6	25	0.17	13	6.6	0.9	2	23	499	520	498	520	0.97
7	25	0.087	6.5	7.6	1.2	1	23	600	623	600	623	0.95
8	25	0.00065	0.049	14.3	0.1	1	22	632	653	632	653	0.96
9	25	0.24	18	6.2	2.4	1	23	662	685	662	685	0.94
10	25	0.0011	0.082	13.6	0.2	2	23	717	738	716	738	0.97
11	25	2.2e-05	0.0016	18.9	5.9	1	23	746	768	746	768	0.99
12	25	0.023	1.8	9.4	1.2	1	23	916	939	916	939	0.92
13	25	0.03	2.3	9.0	0.4	2	22	947	967	947	967	0.95
14	25	1.6	1.2e+02	3.6	0.6	1	23	976	999	976	999	0.86
15	25	1.1e-05	0.00084	19.8	1.9	1	23	1024	1046	1024	1046	0.97
16	25	0.00014	0.011	16.4	0.9	1	23	1053	1075	1053	1075	0.98
17	25	1.5	1.1e+02	3.7	0.2	2	21	1102	1121	1101	1122	0.87
18	25	0.015	1.2	10.0	3.6	1	23	1167	1190	1167	1190	0.96
19	25	0.042	3.2	8.6	0.7	1	23	1227	1250	1227	1250	0.90
20	25	0.015	1.1	10.0	3.1	1	23	1278	1301	1278	1301	0.97
21	25	1.4e-05	0.0011	19.5	0.1	2	23	1325	1346	1324	1346	0.95
22	25	4.8e-05	0.0036	17.8	2.9	1	23	1352	1374	1352	1374	0.99
23	25	2.3e-06	0.00018	22.0	2.0	1	23	1380	1402	1380	1402	0.97
24	25	6e-08	4.5e-06	27.0	2.4	1	23	1408	1430	1408	1430	0.99
25	25	0.00018	0.014	16.0	0.5	1	23	1436	1458	1436	1458	0.97

Sequence Information

Coding Sequence: ATGTTGCCGACAAATATTTGCCGTACATGCACTCTGCATGACGATAGCTTACTTCCGCTTGCAACACCCACagataaatatgcaaataagaGTTTAAATGATATGTTACTCGAATTGACACAAAATGATCCCCTGCTGCAGGAGCATGCGGATGAAAGTCTGCCGCAGTACTTGTGTATTTGCTGCTTGCACAAGTTGGAAGCTGCGTATGCGTTTGTATTGCAGGCGCGCCAGGCTCAagagcaactgttgttgcagctgcgcaAGGGCTTGCAGACACAGTGCTTGGACGAGATGCCCATAGACATTAACTTGCAGCACATCAAAACCGAAACTATCGTTGACATGCAATTAACTAGCAAAACCAAAAATGAAGAACATGAGACGAAGGCTGAAGAGAGGGAGCACGAGATTACCGCAGTGTCTATTCCAGACCTGAAGTGGCAGCCAGACAGCGATAGTGAGAGCAATCAGACTGCTGTTGATGACCAGGACGTGGACTTTAAACCAAAGCAGTTGCGGCGCAGCGCACGtaaagccaaagccagcaCAGACAGCGAAAATGAAGCAACATCTGCACATACGAATCCCATGCCTGTCAAACGTCGTCGTGGCCGCCCAGCACGTCCACTGACAAAGGAGACTATCAACGAAGAAGGACGGCATGTGTGTGAGGTATGTGGAAAGACCTTTTCTTGGTACCGCGATATGCAACGCCATTCGCGCATACACTTTGAGCAAGCGACCTTTGTGTGTGACAGTTGTGGCAAGAGCTTCCTACGCAAAGACAAGTACATGTTTCATCTGCGATCGCACGAAAAGCGTGCAGCCAAGAATCACGCCATGCAGCTGAGCAGCGAATGGCGCTTCGCTGAACGCCTGTACAACTCTGGACGGCTCAAACGTGCGGAGTGCAAGCTGTGCGGCGTAAAATACCAGCGTATAGGGGATCTGCGCGATCATATGGTCTGCCATAAGAACATTGAGACTTTGTCCGAACTGAGTCTAGAGTGTGATGTTATCAGAGAACAATTTGccaaagagcagcagcagttagaCTTGGCGCTGATAAAGCAACAGGTGTGCGCAGACATTGCCAATGGACGAGGTCAGCTGGACAAATACTGCGCTGTGGTCAACGCGTACGGCTATGAGCTCTGTCTTAGTGACTCAGACGAAGATGTAGCTGACCGACCTAAATACCAGTGTCTGCCATGCAACATCAACTTCACGCGCAAATATCGTCTTATGCGGCACACACTGGAGGAGCATACACAGGCAGACTCAACAGCGTCTTGGCAACGCTGTGACGTGTGCCAAATTGGTTTTGTATGTGCGAAAATGCTGGAGCAACATCAGCGCACGCAGTGCCACAGCAAACTGAAGCGTTACAGCTGCCCAAACTGCCCAGGTAAATTTCTGTGGCTACAGAACCTGGAGCAGCATGCGTGCTTGCAGCATGGAAAGCAGCACGAggagcaacggcagcaaaagCAGTGTTGTCTCTGTGATATCCAACTGAGCAGCATGTTCGAATTGCGCGCCCATTTGCTAATCCATCAAGATGGACGCACTGGTATATATCCAGAGCAGCAGGCGACCTTCTTTCGCACTTACTATCCCAATGGTCTTGACTGCAGCGTGGCTGAGCTGAGTGCACGCATTGCCGCCGATTTCAAGGCGGAGGATTATGGCCGATACTTTAATGCCAGAACGAGAAACGGTGAGGAGCTCGATTTCTTCGCCTCGGACTCTGATATGAGTGATGCTGACCAGCAGAGTACTGGCGGGACGCTACATATATGTTCCTTGTGTGGAGTGACGAAAAGGCGCCTGAGTCAATTGCTCGAGCATCAGCAAAGTCAGCATAGTGAGGTAGAGGAAAGGCTGCCATACGTCTGTGACGACTGCGATTTGGGCTTTGTAGCCAACTCGCTGCTCCAACAGCATCGCCGAAGGGTCTGTGCCAAGCAGCATGCCAAGTACGACTGCCAGCAATGCAATCAGCGGTTTTACTGGCTTTCCAATTACGAGTTGCATATGCATTTGCAGCACGAGACTCAAGCCGAGTTGCAGACGGATGTTGTCAATCAACAGGAACAAGAGTCAAGTACGAGAAGCAAGCGCCAGTCTACGGCGACCAAGTTGCAGTGCGGCGAATGCGAAAAGGTGTTCATCTGGCCTAAGGATCTGACGAGGCACAAGCGCCTACACCAGCCACAAGCTTTGGCACAGTTCCAATGCTTGCACTGTGATCGCAAGTTCCATCGCAAGGATGGGCTCAAATCCCATATGCGCGTGCATGGCGAACAGCAGGCAGAAGCGTCGGCTGCCAGTGAACAAGTTCCATCTATGCTGCAGCGCATGCCTGTGGTGCTCACCCAACTGTGTCGACCCAATGGCTGCAAGCAAATTCAATGCATGATCTGTCTCTCGCAGCACACAAAAATCTCTGATCTGCGCACGCATCTGCTTAACCATCAGTATTCGGTAAAATTTGGAGAGGAGCGGGGCCAACCGGAGAGCATAGAGGGAATTTCACGTTCTCTATATCCAGAACTAGCAGCACCATTGGAGTATCAGCAATTAATCGAACGCATTCAGAGTGATGTCGCAAAAGGCGTGGAGCTGGAAAGATTCATATCCATTACCAACGAGGCGGGCATTGAGCTCAGCCTGGACAGCAGTGAGACGGAAACCGATTCGGACTCTGCCGAGGCAGTCAGAAGCAACAGCGGACATCACTATAGCTGTGAGCTCTGCCAGTTGAAGGTATCGCGCAAGCATCAGCTATACGCCCATGAGCTGGAGCAGCATTCGTGGCAGGAGGCGTCCCGTGTTTGCAGCTATTGCCAGGCGAGATTCGTAAATGAGCAGCTACTAGATCATCACTATCGGACGCTCTGTCGCAACGTGCACCGCCGCTTTTTTTGTCGTAAATGTCCACTACGATTCCGCTGGCGCGAGAATATGAGGCTGCACTCGGACGTGGCGCACAATGAAGCCAGAGCTGAGAAATCGAACTTGGGCATTAAGTTGAACGGATCGCCCCTGTTACCCGTCGTTACTTACGACTGCACCGAATGCAATCGTagctttaaaatgcaaaaggaTCTCACCAGGCACACTCTGATGCACGCCCAGGAGTCAAGCATTTATCGTTGTCGCTGGTGTGCACGACGTTTCTACCGCCAGGCCAATCTACTGCAGCACATTGAGCGTCACGGCATTAGCGCCGAACAGCTGCCCTATGCTGAGGCTCTACTCAATGCCAGCCGTCACCCGCATGGCCAGAAGTGTATCCAGTGCAAGGTGTGCAACGTGACCTATCCCACCattgctgcgctgcgctgtcaTCTGCAATCAGCGCCAGCAGGCACCCATCATGAGTATGGCTCGTTGCTCAATTACTCCATTACCAATCAGTTGGGCTACGAGCTGCATCTGGAGGACTCGGAAACAGATGAGGAGGCTAAGCCGCCAGGCACGCCAATGCACTACACCTGCGGCATATGCCAATTGCGCTGTGTGCGCAAATTTGAGCTGCACCAGCATCAGCAAGCGATGCATCGACTGGAATGCATAACCGAAGGTTGCGATATCTGCATCTTTAAGAGTGTCTCGGCAGATCTCATTGCCTATCATCGACGCGTCTTGTGCAATAATACGGAGAAACACTTCAAGTGCTCCAAGTGTGGCTACAAGTTTATGTGGGAAACGAATTTGTTGCAGCATGTGGAGCTGCAGCATCCCAGCAGCGAGAGTAGCGAAACGCAGCCGGGTGCAAGTGCTCTGGCTGTGCAGGAGACAACCAGTGCAGAGTGCCAGATATTCCAGTGCGGCCAGTGTCCTAGTAAATATAATCGCAAGGATCGCCTCACTGCCCATGTAAAGAAATGTCATACAGTGGGAGCAAGTGGCGCAACGAGGCTTATGAAAAATTCAACTGGCGGCAAGCAGCAGAAAAGTTTTCTGTGCGCTTTCTGCGGCAAGGCGGTTAGCTCCTCCTCCAATCTGATTATACACATACGTCGCCATACTGGCGAGAAGCCTTTTAAGTGTGACTACTGCGACATGGCATTTCCACGTTCCTCCGATCTGCAGTGCCACCGACGCACTCACACGGGAGAGCGGCCGCACGTCTGTACCGTTTGCCAGAAGGGCTTTGCCCGATCCTACAAGCTGCAGCAACACATGCGCATCCACAATGGCGAACGACCATATAAGTGTACTTATTGTGACAAGAGCTTTACTCAGTCGAATGATCTGACTCTTCACATACGGCGGCACACAGGCGAGCGTCCCTATCAGTGCAATACGTGCGGCGAGCGTTTCATTCAGGGCACAGCTCTAAAGAATCATCGCCTTCAACATGGACACCACGATACGGAAGTGGACCAGGTCAAGGATAATTAA
Protein Sequence: MLPTNICRTCTLHDDSLLPLATPTDKYANKSLNDMLLELTQNDPLLQEHADESLPQYLCICCLHKLEAAYAFVLQARQAQEQLLLQLRKGLQTQCLDEMPIDINLQHIKTETIVDMQLTSKTKNEEHETKAEEREHEITAVSIPDLKWQPDSDSESNQTAVDDQDVDFKPKQLRRSARKAKASTDSENEATSAHTNPMPVKRRRGRPARPLTKETINEEGRHVCEVCGKTFSWYRDMQRHSRIHFEQATFVCDSCGKSFLRKDKYMFHLRSHEKRAAKNHAMQLSSEWRFAERLYNSGRLKRAECKLCGVKYQRIGDLRDHMVCHKNIETLSELSLECDVIREQFAKEQQQLDLALIKQQVCADIANGRGQLDKYCAVVNAYGYELCLSDSDEDVADRPKYQCLPCNINFTRKYRLMRHTLEEHTQADSTASWQRCDVCQIGFVCAKMLEQHQRTQCHSKLKRYSCPNCPGKFLWLQNLEQHACLQHGKQHEEQRQQKQCCLCDIQLSSMFELRAHLLIHQDGRTGIYPEQQATFFRTYYPNGLDCSVAELSARIAADFKAEDYGRYFNARTRNGEELDFFASDSDMSDADQQSTGGTLHICSLCGVTKRRLSQLLEHQQSQHSEVEERLPYVCDDCDLGFVANSLLQQHRRRVCAKQHAKYDCQQCNQRFYWLSNYELHMHLQHETQAELQTDVVNQQEQESSTRSKRQSTATKLQCGECEKVFIWPKDLTRHKRLHQPQALAQFQCLHCDRKFHRKDGLKSHMRVHGEQQAEASAASEQVPSMLQRMPVVLTQLCRPNGCKQIQCMICLSQHTKISDLRTHLLNHQYSVKFGEERGQPESIEGISRSLYPELAAPLEYQQLIERIQSDVAKGVELERFISITNEAGIELSLDSSETETDSDSAEAVRSNSGHHYSCELCQLKVSRKHQLYAHELEQHSWQEASRVCSYCQARFVNEQLLDHHYRTLCRNVHRRFFCRKCPLRFRWRENMRLHSDVAHNEARAEKSNLGIKLNGSPLLPVVTYDCTECNRSFKMQKDLTRHTLMHAQESSIYRCRWCARRFYRQANLLQHIERHGISAEQLPYAEALLNASRHPHGQKCIQCKVCNVTYPTIAALRCHLQSAPAGTHHEYGSLLNYSITNQLGYELHLEDSETDEEAKPPGTPMHYTCGICQLRCVRKFELHQHQQAMHRLECITEGCDICIFKSVSADLIAYHRRVLCNNTEKHFKCSKCGYKFMWETNLLQHVELQHPSSESSETQPGASALAVQETTSAECQIFQCGQCPSKYNRKDRLTAHVKKCHTVGASGATRLMKNSTGGKQQKSFLCAFCGKAVSSSSNLIIHIRRHTGEKPFKCDYCDMAFPRSSDLQCHRRTHTGERPHVCTVCQKGFARSYKLQQHMRIHNGERPYKCTYCDKSFTQSNDLTLHIRRHTGERPYQCNTCGERFIQGTALKNHRLQHGHHDTEVDQVKDN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00509945;
90% Identity: iTF_00545378;
80% Identity: -