Basic Information

Insect: Drosophila meridiana
Gene Symbol: RREB1
Assembly: GCA_035045185.1
Location: JAWNPF010000151.1:3812396-3818522[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.0057 0.43 11.3 0.6 1 21 247 267 247 269 0.96

2 14 0.00033 0.025 15.2 0.2 1 23 279 301 279 301 0.98

3 14 7.9e-05 0.006 17.2 7.3 1 23 307 329 307 329 0.98

4 14 2.5 1.8e+02 3.0 0.0 3 23 514 536 513 536 0.90

5 14 0.044 3.3 8.5 0.8 2 20 542 560 542 562 0.93

6 14 0.0087 0.65 10.7 0.1 1 23 718 740 718 740 0.97

7 14 1.2e-05 0.00091 19.7 0.7 1 23 750 772 750 772 0.99

8 14 0.00081 0.061 14.0 2.0 1 23 778 801 778 801 0.97

9 14 0.0029 0.22 12.2 2.0 1 23 1050 1073 1050 1073 0.95

10 14 8.5e-05 0.0064 17.1 0.3 2 23 1400 1421 1399 1421 0.97

11 14 0.14 11 6.9 6.3 1 23 1427 1450 1427 1450 0.97

12 14 3.1 2.4e+02 2.7 4.2 1 23 1575 1598 1575 1598 0.88

13 14 0.0083 0.62 10.8 0.5 3 23 1658 1678 1656 1678 0.96

14 14 0.0013 0.099 13.3 4.8 1 23 1684 1706 1684 1706 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.0057	0.43	11.3	0.6	1	21	247	267	247	269	0.96
2	14	0.00033	0.025	15.2	0.2	1	23	279	301	279	301	0.98
3	14	7.9e-05	0.006	17.2	7.3	1	23	307	329	307	329	0.98
4	14	2.5	1.8e+02	3.0	0.0	3	23	514	536	513	536	0.90
5	14	0.044	3.3	8.5	0.8	2	20	542	560	542	562	0.93
6	14	0.0087	0.65	10.7	0.1	1	23	718	740	718	740	0.97
7	14	1.2e-05	0.00091	19.7	0.7	1	23	750	772	750	772	0.99
8	14	0.00081	0.061	14.0	2.0	1	23	778	801	778	801	0.97
9	14	0.0029	0.22	12.2	2.0	1	23	1050	1073	1050	1073	0.95
10	14	8.5e-05	0.0064	17.1	0.3	2	23	1400	1421	1399	1421	0.97
11	14	0.14	11	6.9	6.3	1	23	1427	1450	1427	1450	0.97
12	14	3.1	2.4e+02	2.7	4.2	1	23	1575	1598	1575	1598	0.88
13	14	0.0083	0.62	10.8	0.5	3	23	1658	1678	1656	1678	0.96
14	14	0.0013	0.099	13.3	4.8	1	23	1684	1706	1684	1706	0.99

Sequence Information

Coding Sequence: atGCTGgccacacagcagcagcagcaacagcagccacaacagcaacatacagcagcagcagcagcagcagcggcagcagcaaccgcagtAACTCTTGAGGATGCGGTCTTGGAGCGACAGCGCCGTGACTCCAGCACCTCGGAGTCATCGCTGGAGCATCTGGATCTGGGTCGCACGCCAAAGAAActgagcagcaacagcggcgcGCTGCAGCCGACGTCGACGCCGCACGTTGAGGTGACGTCGCGGAAGCGCAAGatgcgccagcagcagcagcaacaacagcagccaatcCTGTACTCAGACGAGGaggacgagcagcagcagcagcagcagcaacagcagcagcaacagttgctggaGCAGTCTGTGCATCGCATTCGCCACAAGCAACGGCGCAGCGGCAATGCGGTCGCTGCCGCAGCCAGCGCCAGCATCGTCGTCGACTACAGCGTCGGCAGCGACGCCAGTTCGCTGCGCAAAAAGTTTCGCCTGAAtcgcagcagcatcagcgccCACAACGGCGACCTCTCCGAGTCGGGCTTCGTCGATGGCAGCGCGCACAGCGGCTATTTGCTCAGCGCCAGCGGCGCAGCGCAGtcggcagcgacggcggcgcagcagcagcaacagcagcagcagccgggcTCGGGCAGCAGCTCGGGCGGCTCCTCGCCGCAAGGCCTGTGCCATTCGAGCGCCGAGTCCGGCATCGGCGCCGGCGACGAGCACATGAAATACGTCTGCCCCATCTGCGAGGTCGTCTCGGCCACGCCCCACGAGTTCACCAATCACATTCGATGCCACAACTATGCCAACGGCGACACCGAGAACTTCACCTGCCGCATATGCTCCAAGGTACTCTCGTCCGCCTCCTCGCTGGACAGACACGTCCTGGTGCATACCGGGGAGCGGCCCTTCAACTGTCGCTATTGCCACTTGACCTTCACGACAAACGGCAACATGCATCGGCACATGCGCACACAcaagcaacaccagcaacaccaacagcagcagcagcagcaacagcagcagcaacagcagcagcagcagcaccaacagcagcaacagctgccgcagcagcagcaacagttgcagcgaCATCAGCAACACGCGGCAGCAAATGCTGTGGCTCAGCGCGCCGAGAGCTATGAGAGCGATGCCAGCTGCTCCACGGACAtatccagcagcagcagcagcgcagccagcaacaacaacaacaacaacagtagccaagcgaacaacaacaacaacaacgaggagcagcagcagcagcaacagctgaagctgaagacgaacatcaacaacaacaacatcattgTCAGCGACGAGCGAGCGCTGAACATGGACATCGATGGCGATAGGGAGGATGAGGGGGAGCGGGAGGCATGCGAGACAGCCGATGGGGAGAGCGTGGATGTGACACAGATGATAACGAGCACACCCGACGTGGCCACACTGCTGGCAACGTCCTCGGGCAACAGCAGCCCGCGCACGCCGGAGCCCGAGGCGGAGGTGGAGGCGGAGACGTTGCCCAGCTGCCCCGTGTGCAATGCGGGCGAGTTCGAGACGCCGGCCGCGCTGTACGCCCACCTGGAGACGGAGCACGCGGACATACCCGCCAAGTGCCGCGAGTGCGAGGTGATCTTCGCcacgcagcggcagctgcaggcGCACAGCTGCCGGGGactgcagctgccgccgctgctgggCGCCAGCTCCTCGCCGCTGCACAAGCAGGAGCCGGCGGAGGAGGAAGACGacgagcaggagcagctgcagcaccgGGAGCAGGAGGCCGAGGCGGaggctgacgctgacgctgaggaggaggaggagcagatGCGGCTGCAGGCAAACAGCGAGCGGGACGAGTTCTTTCAGCAGCTCTACCTCAAGGGCAAGTCGGGTGGCTCCTCGCTGCCGTCGCCCATCAAGCACGAGCCGTCGGAGCAGCGCCAGGATCTGGCCGACATACAGAGCATCCTGCACAtgaccagctccagctgcaccTCCAGCTTCCTGCGCAACTTCGAGCAGAACGTGAACACGCCCTGCTCCAGCCAGTACAGCCTGGACGGGCGCGACGGCGAGGAGGAGGCCCAGGACGCCTTCACCAGCGAGTTCCGGCGCATGAAGCTGCGCGGCGAGTTCCCCTGCAAGCTCTGCTCGGCCGTCTTTCCCAACTTGCGCGCCCTCAAGGGCCACAACCGCGTCCACCTGGCTGCCGTCGGCGCCGCCGGCCCCTTCCGCTGCAACATGTGCCCCTACGCCGTCTGCGACAAGGCGGCGCTGGTGCGGCACATGCGCACCCACAACGGCGACCGACCGTACGAGTGCGCCGTCTGCAACTACGCCTTCACCACGAAGGCCAACTGCGAGCGGCACCTGCGCAACCGGCACGGCAAGACCAGCCGCGACGAGGTGAAGCGCGCCATCGTCTATCATCCGGCCGAAGACGCCAGCTGCGAGGACATCAAGCCCAAGCTGGACCCCGATCTGTCGGAGCTCAGCTTTCGCTCGCTCAGTCCGTCGCCGTCCGCGACGAACGTGGAGTCCAGCTCGCAGCTGAAGCACATGTTGTTGGCGGAGCAGCCcatcaagcagcagcagcagcagcaaccgccgCAGCCTCCACTGAAGATTCAGGTGAAGAGCTTGGATCAGCTGGTGGAGAAGCCGCTGGCGCCTGCCATGGACCTCAGCATGGATGTGCTGGATCTCAGCAAGAAGCCGCAGCGCGAACACGATCTgctcctgcagcagcagcagcagcagcagcaacagcaacaacagcaacagcaacaacagcagcagcagcaacagcagcagcaacagttgctttTCAATCCGGGCGATGCGGCGACGTACATGCAGCTGCTCCGGAACCTGATGCTGCAGCAGTCGTCCGGCTTTCCGTTCTTCGGGCTGATGGCGCCGCCACCAGCCGCTGCGCTGGAGAAGTCGGCGTCAGCGCTGGCAGtgccagcgacagcaacagcatctgctgctgctgctgcagtgccgCCGCCCTTGGGCCTGCCCCTGGGCGTGCCGGTGCCGGCGGCGGGGCCCGTCAAGATGGTCATCAAGAACGGCGTGCTGATGCCCAAGCAGAAGCAGCGCCGCTACCGCACCGAGCGGCCCTTCGCCTGCGAGCACTGCTCGGCCAGGTTCACGCTGCGCTCCAACATGGAGCGGCACGtcaagcagcagcatccgCAGTTCTAcgcgcagcggcagcgcagcGGGCACCACGTGATGCGCGGGCGGGCAGCCAACTCGGGCGCTGCccaggcagcagcggcggcggcggcagcggcagcagcagccgcagcagcagcagccatgaCCAAtctgcaccagcagcaccagcagcagcaacaccagcaacagcagcagcatccgccCATATCGGAGCAGGTCAAGTATGCGATCCTGGCGCAGCAGCTGGCGCGCAAGGACACGGACTTGCTGCAGCAGGCGCTGGCGCATGGCTCCAGCAGCGTCGCCGTCAATCCGCTGCTGCACTTTggctacaacagcagcagcagcaatgctaATGGCAGCAATcagtcacagcagcagcagcagcagcaacagttgccagtGGATGACGATGAGCCGCCCAAGCTGATCATTGATGAAGACGACGAGGATGACTTTGAGGACATAGAcgaggaagaggaggaggaggaagaggacGAACTAGACCAagacgaacagcagcagcaggaggagcagcagcagcagcagcaacacgagcaacaggagcagctgcaactgccgGCCATTGAAATTGATGCCAAAGAGGAGCCAGAGGAGCTAGCCGAGacgcagctgaagctgaagctgaagcccGGCGAGCCGAGCACCATGAAGACCATGATTGCCCAGGCCGAGTCGGTGGCCAAGTCGCTGAAGGAGGTGGCCAGCTCGCCGTTCAAGGACGAATCTCAGGACCTGGTGCCGGTGGCCAAGCTGGTGGACAACGCGACCAGCAACCAGGTGTCGTTCAACAGCTACTTCCGGCCCAGCGACGTGGCCAACCACATGGAGCAGAGCGACGAGGAGGGCCTCGTGGCCTCCGGCAGCGCCAGCGAGAGCAACAACTCCGGCACCGAGGAcgtcaccagcagcagcagctgcagcgagcCCAAGAAGAAGTCCGCCTACAGCCTGGCGCCCAACCGGGTCAGCTGCCCGTACTGCCAGCGCATGTTCCCCTGGAGCAGCTCGCTGCGCCGGCACATCCTTACCCACACCGGGCAGAAGCCCTTCAAGTGCTCCCACTGCCCGCTGCTGTTCACCACGAAGAGCAACTGCGACCGGCACCTGCTGCGCAAGCACGGCAACGTCGAGTCCGCCATGTCCGTCTACGTGCCCACCGAGGACGTCAGCGAGCCGATACCCGTGCCCAAGTCCGTCGAGGAGATCGAGCTGGAGGAGCAGCGGCGCCGCAAGGCGGCCGAGCAGGAGcgccagctggagctggaacgCGAGCGGGAGCGCGAGCGTGAGCTGGAGCGGGAGCGCGAACTGGAGCGCGagcgcaagcagcagcagctcatccAGCAGCTAACGGCGGCGGCTCAACTCAGCCAGCAGATGGTGGCAGCAGCCCAAGCCGCTCAagctgccgcagccgcagctgccactagcagcaccagcagcaccaccggCACCACTGGCACCGCTGAGGCCAATGGCAGCGAACTGCCCTACAAGTGCCACCTGTGCGAGTACTCGTTCGGCGAGCGGATGCAGTGCCTCGACCACATCAAGCAGCAGCACGCCCAGGAgtttgcgctgctgctggccaaggGCGCCATCGAGacggagcaggaggcggcagcagcagcagcagcgactgccactgcgactgcgacagcgactgTCGGCTCCGAGGACGAGTCCAGCACGGGTCGCGGCTCCGGCAAGTATCCGGACTACAGCAACCGCAAGGTGATCTGCGCCTTCTGCGTGCGCCGCTTCTGGTCCACCGAGGACCTGCGCCGGCACATGCGCACCCACTCCGGCGAGCGGCCGTTCCAGTGCGAGATCTGCCTGCGCAAGTTCACGCTGAAGCACAGCATGCTCCGGCACATGAAGAAGCACAGCGGGCGCAGCCACAACGGCGAGCCGGGCGCCTCCGACTGCTCCGACGACGAGCAGATGGCGACGCCGCCGacgacgccaacgccaacggcCATGGCGATGGCCATGCCCATGCCTATGCCTATGCCGATGCCAAtgcccagcaacaacaacaacaacaacaactcttgccacaacaacaacaacaacaacagcaacagcagcaagagcgGGCGTCTGCCCAAGCTGCACGAGCTGCTGGATAAGGCGAACGAGTGGCGCGTCAGTCGCCTGGGCGAGCACAAGGAGAACATCGCCGACTCCACTGCGCCCACAACGCCAGccgctgtgggcgtggccagcggCGATTTCCTGGGCAATCTGCTGGGCATCACCGACCAGGGCATCCTCAACAAGCTGCTCAGCTCGCCGGACGAGGCGGCCAAGCTGCTGGGCGTGGAGAAGTGA
Protein Sequence: MLATQQQQQQQPQQQHTAAAAAAAAAATAVTLEDAVLERQRRDSSTSESSLEHLDLGRTPKKLSSNSGALQPTSTPHVEVTSRKRKMRQQQQQQQQPILYSDEEDEQQQQQQQQQQQQLLEQSVHRIRHKQRRSGNAVAAAASASIVVDYSVGSDASSLRKKFRLNRSSISAHNGDLSESGFVDGSAHSGYLLSASGAAQSAATAAQQQQQQQQPGSGSSSGGSSPQGLCHSSAESGIGAGDEHMKYVCPICEVVSATPHEFTNHIRCHNYANGDTENFTCRICSKVLSSASSLDRHVLVHTGERPFNCRYCHLTFTTNGNMHRHMRTHKQHQQHQQQQQQQQQQQQQQQQHQQQQQLPQQQQQLQRHQQHAAANAVAQRAESYESDASCSTDISSSSSSAASNNNNNNSSQANNNNNNEEQQQQQQLKLKTNINNNNIIVSDERALNMDIDGDREDEGEREACETADGESVDVTQMITSTPDVATLLATSSGNSSPRTPEPEAEVEAETLPSCPVCNAGEFETPAALYAHLETEHADIPAKCRECEVIFATQRQLQAHSCRGLQLPPLLGASSSPLHKQEPAEEEDDEQEQLQHREQEAEAEADADAEEEEEQMRLQANSERDEFFQQLYLKGKSGGSSLPSPIKHEPSEQRQDLADIQSILHMTSSSCTSSFLRNFEQNVNTPCSSQYSLDGRDGEEEAQDAFTSEFRRMKLRGEFPCKLCSAVFPNLRALKGHNRVHLAAVGAAGPFRCNMCPYAVCDKAALVRHMRTHNGDRPYECAVCNYAFTTKANCERHLRNRHGKTSRDEVKRAIVYHPAEDASCEDIKPKLDPDLSELSFRSLSPSPSATNVESSSQLKHMLLAEQPIKQQQQQQPPQPPLKIQVKSLDQLVEKPLAPAMDLSMDVLDLSKKPQREHDLLLQQQQQQQQQQQQQQQQQQQQQQQQQQLLFNPGDAATYMQLLRNLMLQQSSGFPFFGLMAPPPAAALEKSASALAVPATATASAAAAAVPPPLGLPLGVPVPAAGPVKMVIKNGVLMPKQKQRRYRTERPFACEHCSARFTLRSNMERHVKQQHPQFYAQRQRSGHHVMRGRAANSGAAQAAAAAAAAAAAAAAAAAMTNLHQQHQQQQHQQQQQHPPISEQVKYAILAQQLARKDTDLLQQALAHGSSSVAVNPLLHFGYNSSSSNANGSNQSQQQQQQQQLPVDDDEPPKLIIDEDDEDDFEDIDEEEEEEEEDELDQDEQQQQEEQQQQQQHEQQEQLQLPAIEIDAKEEPEELAETQLKLKLKPGEPSTMKTMIAQAESVAKSLKEVASSPFKDESQDLVPVAKLVDNATSNQVSFNSYFRPSDVANHMEQSDEEGLVASGSASESNNSGTEDVTSSSSCSEPKKKSAYSLAPNRVSCPYCQRMFPWSSSLRRHILTHTGQKPFKCSHCPLLFTTKSNCDRHLLRKHGNVESAMSVYVPTEDVSEPIPVPKSVEEIELEEQRRRKAAEQERQLELERERERERELERERELERERKQQQLIQQLTAAAQLSQQMVAAAQAAQAAAAAAATSSTSSTTGTTGTAEANGSELPYKCHLCEYSFGERMQCLDHIKQQHAQEFALLLAKGAIETEQEAAAAAAATATATATATVGSEDESSTGRGSGKYPDYSNRKVICAFCVRRFWSTEDLRRHMRTHSGERPFQCEICLRKFTLKHSMLRHMKKHSGRSHNGEPGASDCSDDEQMATPPTTPTPTAMAMAMPMPMPMPMPMPSNNNNNNNSCHNNNNNNSNSSKSGRLPKLHELLDKANEWRVSRLGEHKENIADSTAPTTPAAVGVASGDFLGNLLGITDQGILNKLLSSPDEAAKLLGVEK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00512904;
90% Identity: iTF_00545423;
80% Identity: -