Dmer010180.1
Basic Information
- Insect
- Drosophila meridiana
- Gene Symbol
- -
- Assembly
- GCA_035045185.1
- Location
- JAWNPF010000135.1:2560419-2562716[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 12 0.032 2.4 9.0 7.0 3 23 231 251 231 251 0.99 2 12 0.22 17 6.3 2.1 1 19 257 277 257 282 0.85 3 12 0.00017 0.013 16.1 0.7 1 23 286 311 286 311 0.94 4 12 0.00026 0.02 15.5 4.7 1 23 321 343 321 343 0.97 5 12 0.0012 0.091 13.4 1.6 3 23 352 372 350 372 0.96 6 12 0.0013 0.1 13.3 1.2 1 23 378 400 378 400 0.98 7 12 0.0023 0.17 12.5 2.8 1 23 406 429 406 429 0.97 8 12 0.00021 0.016 15.8 1.1 1 23 435 457 435 457 0.97 9 12 0.056 4.2 8.2 0.8 2 23 464 485 463 485 0.95 10 12 4.5e-06 0.00034 21.1 0.5 1 23 570 593 570 593 0.97 11 12 0.012 0.92 10.3 1.3 1 23 599 621 599 621 0.96 12 12 1.7e-05 0.0013 19.2 1.8 1 23 627 650 627 650 0.97
Sequence Information
- Coding Sequence
- ATGAATGAAAGAGCTACATACTCCATAAACTCGATATGTCGCATATGCTTGAACCATCTGCAAGACGGTCCGGCATACGACCTGTTTCTTATCGCTGGTCTGGCCAagaaattgtgtgtgtgcacttctCTCTCAGTGGAAGAGCACGATGGCTTCCCGAAGAACCTTTGCTCCACTTGTCATTCCCGACTCAACGACGTGGACGAATTTCAAGAGCTTTGCGTGGCTTCAGTGCAAAAGTTTCAAGAAATGGTCGCCAACAATCAGATTGTTGACGATGTTGACAACGTTATTGTAATCAATGATGTATTGACTGATGTGGACATGGAAGCGGATCACTTAAAGTTCGATCCACTtctaaatactaaaatagaaattgtggAGAGTGATGTTTTTAAACTCCTGGAAGATGTGGACAAAGAAGCTGAGGACGTCGAGAAGAAACTCTTAAGCGAAAACGAATGTGATAACTATGAAGATCCGGGATTTGATGCAAACAGCTGCAGCTCTGAAGATGATCTGCCCCTGACCCGTCTACGCTGTGTGACCAGAgcatcaaaatcaaaaccGCACGACAAATCTGTTGTTGATAATAACGAATCTTTAAGTACCTCTGAATGGAATAACAACATCGATGAGTGCAAGGAGACGCCTAACAAGAAAACCAAATGTAGACGCATTCTGATTGGTTGCCACATCTGCCATCAGAAATTCAGCAGCAATGAGCTTTATGACGAGCATATGAAACACCACAACGATCTTCTACCTTTCCAGTGTACTGAAGAGAACTGTAAGAAGGGCTTCACTACGTCTAATGCATTAAGTTTTCACAAGGAACATTCTCATTTGCCTCTTCATCCCTGTTCCTTCGAAGGATGTGGAGAGACATTTTCTCGAGCGATTTTACTCACTAACCATAAGAAAAGAGTTCACAAAATCGCTCCCTCTCGAGGTAAGGATCATCCTTGTACGGAGTGCGACAGAGTTTTCCGCTGTTCATCGGCCCTTAAGAAACATATGTATAGGCATACTGGGAAGGAGAAGCCGCTTGCTTGTAACATCTGCACCAAACGCTTCATCTTAAACTGCGAACTCAAGGAACATCTCTTGCGTCATGCCGGTGTAAAGAATCACGTGTGTCCCCACTGCGGATTGGGTATGACCACGCGACAGGAGTGGAACAAACACATATTGACACACACCAGAGAAAAGAAGTTCAAGTGCGATCAATGCAATCATGCGACGCACAACAAACAGGCTCTGAGAAACCATATTAATGTTgtgcatttaaaaattaagaattatgCCTGTCAGTATTGCGGAAAGCGGTTTGCCAAGTCGTTTGCCCGCAAAGTCCACGAAAGAAGCCACACCGGGGAAAATGTTTGTGAATGTAAACTCTGCGgtaaaattttactttttgaaGAGGCTTTGACCAAACATTTGAAGATTCATGAGACGCGCGTTCCTCGCGGATCAgggaaaaatatgaaaaaacgAGTATTTAGTAATGCGCCAAAGAAGGAGAATATGGAAAAAGATGGTGAGGATCCAGCGGACGTCAAACCCAAACCAACACAGGAAACCAAGCCGAACAATTCAAATAGGCTGGAGCGTGTTGATATATCCCAGTTGGCCGGTACACCCGTCAATCCCATTATGGTGGAGTCTTCATCTGAAGTTATCTTTACAGTGAAGGACGGGCAATACATTTGTTCAGGATGTGGGCGTGCCTTTAACCATCTGGCCAATTTGAAGCTTCACTATAAGATAATACACTTAAAGATAAAAGATTTCGCGTGTAGCTTTTGTTCCAAACGATTTTCAAAGGCACAGATCTTACGGAATCACGAATTGACGCACACCGGCGAAAAGCCGCATGAGTGCAAGATATGTGGTATGCGCTTCCGTCAATCGACAGGTATGAAGTtacatataagaaaaatacatgAAAACCCGGCGAAGCCAGCAAGAGAGCCGAAACCCAAAACACAACCCAAAACTGAAAGACGAAAGATGAATCTTAACGAGAAACCGCCTAAGATTCTGGATGAATATCAGGATCCTGCAGCAGAGAGGGCGGCGGCTACCGCCGCACTTCTCATCCAGCAACAGAAGGAATATAAAGCTAAACAAAAGGCAGAGGAGGAAGCGCGTAAAATTCAAGAGGCTGCATGCGAACAACTTTATATGTTGCAGGAGGAACAGCTAATTAACAAGCTACCCAGTGATAGCTTTCAAGTAAAGAAACCCCAGACAGGCATTACTGTGGATGACCTCAAAAAAAATTCGACTTAA
- Protein Sequence
- MNERATYSINSICRICLNHLQDGPAYDLFLIAGLAKKLCVCTSLSVEEHDGFPKNLCSTCHSRLNDVDEFQELCVASVQKFQEMVANNQIVDDVDNVIVINDVLTDVDMEADHLKFDPLLNTKIEIVESDVFKLLEDVDKEAEDVEKKLLSENECDNYEDPGFDANSCSSEDDLPLTRLRCVTRASKSKPHDKSVVDNNESLSTSEWNNNIDECKETPNKKTKCRRILIGCHICHQKFSSNELYDEHMKHHNDLLPFQCTEENCKKGFTTSNALSFHKEHSHLPLHPCSFEGCGETFSRAILLTNHKKRVHKIAPSRGKDHPCTECDRVFRCSSALKKHMYRHTGKEKPLACNICTKRFILNCELKEHLLRHAGVKNHVCPHCGLGMTTRQEWNKHILTHTREKKFKCDQCNHATHNKQALRNHINVVHLKIKNYACQYCGKRFAKSFARKVHERSHTGENVCECKLCGKILLFEEALTKHLKIHETRVPRGSGKNMKKRVFSNAPKKENMEKDGEDPADVKPKPTQETKPNNSNRLERVDISQLAGTPVNPIMVESSSEVIFTVKDGQYICSGCGRAFNHLANLKLHYKIIHLKIKDFACSFCSKRFSKAQILRNHELTHTGEKPHECKICGMRFRQSTGMKLHIRKIHENPAKPAREPKPKTQPKTERRKMNLNEKPPKILDEYQDPAAERAAATAALLIQQQKEYKAKQKAEEEARKIQEAACEQLYMLQEEQLINKLPSDSFQVKKPQTGITVDDLKKNST
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00544647;
- 90% Identity
- -
- 80% Identity
- -