Basic Information

Insect: Drosophila meridiana
Gene Symbol: -
Assembly: GCA_035045185.1
Location: JAWNPF010000135.1:2564441-2566729[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.2 15 6.4 7.4 3 23 231 251 231 251 0.99

2 12 3.1 2.3e+02 2.7 0.8 1 17 257 275 257 282 0.85

3 12 0.00013 0.01 16.4 0.3 1 23 286 311 286 311 0.94

4 12 0.0045 0.34 11.6 3.0 2 23 322 343 321 343 0.96

5 12 0.0012 0.091 13.4 1.6 3 23 352 372 350 372 0.96

6 12 0.00067 0.051 14.2 1.4 1 23 378 400 378 400 0.97

7 12 0.00057 0.043 14.4 0.5 1 23 406 429 406 429 0.97

8 12 6.9e-06 0.00052 20.5 1.6 1 23 435 457 435 457 0.98

9 12 0.0052 0.39 11.4 0.5 2 23 464 485 463 485 0.96

10 12 2.1e-06 0.00016 22.1 0.9 1 23 567 590 567 590 0.98

11 12 0.00013 0.0095 16.5 1.3 1 23 596 618 596 618 0.97

12 12 2e-06 0.00015 22.2 1.4 1 23 624 647 624 647 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.2	15	6.4	7.4	3	23	231	251	231	251	0.99
2	12	3.1	2.3e+02	2.7	0.8	1	17	257	275	257	282	0.85
3	12	0.00013	0.01	16.4	0.3	1	23	286	311	286	311	0.94
4	12	0.0045	0.34	11.6	3.0	2	23	322	343	321	343	0.96
5	12	0.0012	0.091	13.4	1.6	3	23	352	372	350	372	0.96
6	12	0.00067	0.051	14.2	1.4	1	23	378	400	378	400	0.97
7	12	0.00057	0.043	14.4	0.5	1	23	406	429	406	429	0.97
8	12	6.9e-06	0.00052	20.5	1.6	1	23	435	457	435	457	0.98
9	12	0.0052	0.39	11.4	0.5	2	23	464	485	463	485	0.96
10	12	2.1e-06	0.00016	22.1	0.9	1	23	567	590	567	590	0.98
11	12	0.00013	0.0095	16.5	1.3	1	23	596	618	596	618	0.97
12	12	2e-06	0.00015	22.2	1.4	1	23	624	647	624	647	0.97

Sequence Information

Coding Sequence: ATGAATGAAAGAGCTACATACTCCATAAACTCGATATGTCGCATATGCTTGAACCATCTGCAAGACGGTCCGGCATACGATCTGTTTCTTATCGCTGGTCTGGCCAagaaattgtgtgtgtgcacttctCTCTCAGTGGAAGAGCACGATGGCTTCCCGAAGAACCTTTGCTCCACTTGTCATTCCCGACTCAACGACGTGGACGAATTTCAAGAGCTTTGCGTGGCTTCAGTGCAAAAGTTTCAAGAAATGGTCGCCAACAATCAGATTGTTGACGATGTTGACAACGTTGTTGTAATCAATGATGCATTGGCTGATGTGGACATGGAAGAGGATCACTTAAACTTCGATCCACTtctaaatactaaaatagaaattgtggAGAGTGATGTTTTTAAACTCCTGGAAGATGTGGACAAAGAAGCTGAGGACGTCGAGAAGAAACTCTTAAGCGAAAACGAATGTGATAACTATGAAGATCCGGGATTTGATGCAAACAGCTGCAGCTCTGAAGATGATCTGCCCCTGACTCGTCTACGCTGTGTAACCAGAGCATCAAAAGAAAAAGCGCAGGACAAATCTGTCGTTGATCATAAAGAACCTTCAAGTGGCTCTGAGTGGAATTACAACATCGACGAGTGCAAGGAGACAcctaaaaagaaaaccaaacgTAGACGCATTCTGATTGGTTGTCACATCTGCCATCAGAAATTCCGCAGCACTGAGCTTTATGACGAGCATATGAAACACCACAACGATCTTCTACCTTTCCAATGTACTATAGAAAGCTGTAAGATGGGCTTCACTACGTCTAATGCATTAAGTTTTCACGAGGAACATTCTCATTTGCCTCTTCATCCCTGTTCTGTCGAAGGATGTGGAGAGACATTTTCTCGAGCGATTTTACTCACTAACCATAAGAAAAGAGTTCACAAAATCGCTCCCTCTGGACGTAAGATTCAACCTTGCACAGAGTGTGAGAAAGTTTTCCACTGTGCATCGGCCCTTAGGAAACATATGTATAGTCATACTGGGGAGGAGAAGCCGCTTGCTTGTAACATCTGCACCAAACGCTTCATCTTAAACTGCGAACTCAAGGAACATCTCTTGCGTCATGCAGGTGTAAAGAATCACATGTGTCCCCACTGCGGATTGGGTCTGACCACGCGACAGGAATGGAGCAAGCACATATTGACCCACACCAGGGAAAAGAAGTTCAAGTGCGATCAATGCGATTATGCGACGCACAACAAGCAGGCTCTGGCAAACCATATTAATGTTGTGCATTTAAAAATTAGGAATTATGCTTGTAAGTATTGCGAAAAGCGGTTTGCCAAGTCGTATAGCCTCAAAATTCACGAAAGAAGCCACACCGGGGAAAATGTTTGTGAATGTAAACTCTGTGGTAAAATTTTCCTTGTTGGAGATGCTTTGACCAGACATTTGAAGATTCATGAGATGGGCGTTTTTCGCgcgaaaaatatgaaaaaacgAGTATTTGATAATGCGCCAACGAAGCAGAATATGGAAAAAGATGATGAGGGTCCAGTGGAGGGAAAGCCCAAACCAACACAGGAAACCAAGCCGAACAATGCAAGGCTGGAGCGTGTTGATATATCCGAGTTGGCCGGTACACCCGTCAATCCCATTATGGTGGAGTCTTCATCTGATGTGAAGTTTACAGTGAAGGACGAGCAGTACATTTGTTCAGGATGTGGGCGCGCCTTTAACCATCTGGGTAATTTGAAGCTTCACTATAAGACAATACACTTAAAGTTAAAAGATTACGCGTGTACCTTTTGTTCCAAACGATTTGCAAAGCCACAGAACTTACGGTATCACGAATTGACGCACACCGGCGAAAAGCCGCATGAGTGCAAGATATGTGGTATGCGCTTCCGTCAATCGGCAGGTTTGAAgacacatataaaaaaaatacacgaAAACCCGGCGAAGCCAGCAAGAGAGCCGAAACCCAAAACACCACCCAAAACTAAAAGACGAAAGATGAATCTTAACAAGAAACCGCCTAAGATTCTGGATGAATATCAGGATCCTGCAGCAGAGAGGGCGGCAGCTACCGCCGCACTTCTCGTCCAGCAACAGAAGGAATATAAAGCTAAACAAAAGGCAGAGGAGGAAGCGCGTAAAATTCAAGAGGCTGCATGCGAACAACTTTATATGTTGCAGGAGGAACAGCTAATTAACAAGCTACCCAGTGATAGCTTTCAAGTAAAGAAACCCAAGACAGGCATTACTGTGGATGACCTCAAAAAAAATTCGACTTAA
Protein Sequence: MNERATYSINSICRICLNHLQDGPAYDLFLIAGLAKKLCVCTSLSVEEHDGFPKNLCSTCHSRLNDVDEFQELCVASVQKFQEMVANNQIVDDVDNVVVINDALADVDMEEDHLNFDPLLNTKIEIVESDVFKLLEDVDKEAEDVEKKLLSENECDNYEDPGFDANSCSSEDDLPLTRLRCVTRASKEKAQDKSVVDHKEPSSGSEWNYNIDECKETPKKKTKRRRILIGCHICHQKFRSTELYDEHMKHHNDLLPFQCTIESCKMGFTTSNALSFHEEHSHLPLHPCSVEGCGETFSRAILLTNHKKRVHKIAPSGRKIQPCTECEKVFHCASALRKHMYSHTGEEKPLACNICTKRFILNCELKEHLLRHAGVKNHMCPHCGLGLTTRQEWSKHILTHTREKKFKCDQCDYATHNKQALANHINVVHLKIRNYACKYCEKRFAKSYSLKIHERSHTGENVCECKLCGKIFLVGDALTRHLKIHEMGVFRAKNMKKRVFDNAPTKQNMEKDDEGPVEGKPKPTQETKPNNARLERVDISELAGTPVNPIMVESSSDVKFTVKDEQYICSGCGRAFNHLGNLKLHYKTIHLKLKDYACTFCSKRFAKPQNLRYHELTHTGEKPHECKICGMRFRQSAGLKTHIKKIHENPAKPAREPKPKTPPKTKRRKMNLNKKPPKILDEYQDPAAERAAATAALLVQQQKEYKAKQKAEEEARKIQEAACEQLYMLQEEQLINKLPSDSFQVKKPKTGITVDDLKKNST

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00545434; iTF_00544669;
90% Identity: -
80% Identity: -