Basic Information

Insect: Drosophila melanosoma
Gene Symbol: RREB1
Assembly: GCA_035042045.1
Location: JAWNLY010000210.1:155442-162064[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 13 0.035 2.4 8.7 0.8 1 21 262 282 262 284 0.93

2 13 0.00032 0.022 15.1 0.2 1 23 294 316 294 316 0.98

3 13 0.00024 0.017 15.5 7.2 1 23 322 344 322 344 0.98

4 13 0.23 16 6.1 1.7 2 20 582 600 582 602 0.93

5 13 0.015 1 9.8 0.2 1 23 749 771 749 771 0.97

6 13 1.2e-05 0.00082 19.6 0.7 1 23 781 803 781 803 0.99

7 13 0.0008 0.055 13.9 2.0 1 23 809 832 809 832 0.97

8 13 0.0029 0.2 12.1 2.0 1 23 1109 1132 1109 1132 0.95

9 13 8.4e-05 0.0057 17.0 0.3 2 23 1531 1552 1530 1552 0.97

10 13 0.14 9.6 6.8 6.3 1 23 1558 1581 1558 1581 0.97

11 13 9.1 6.2e+02 1.1 3.4 1 23 1700 1723 1700 1723 0.78

12 13 0.0082 0.56 10.7 0.5 3 23 1780 1800 1778 1800 0.96

13 13 0.0013 0.089 13.2 4.8 1 23 1806 1828 1806 1828 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	13	0.035	2.4	8.7	0.8	1	21	262	282	262	284	0.93
2	13	0.00032	0.022	15.1	0.2	1	23	294	316	294	316	0.98
3	13	0.00024	0.017	15.5	7.2	1	23	322	344	322	344	0.98
4	13	0.23	16	6.1	1.7	2	20	582	600	582	602	0.93
5	13	0.015	1	9.8	0.2	1	23	749	771	749	771	0.97
6	13	1.2e-05	0.00082	19.6	0.7	1	23	781	803	781	803	0.99
7	13	0.0008	0.055	13.9	2.0	1	23	809	832	809	832	0.97
8	13	0.0029	0.2	12.1	2.0	1	23	1109	1132	1109	1132	0.95
9	13	8.4e-05	0.0057	17.0	0.3	2	23	1531	1552	1530	1552	0.97
10	13	0.14	9.6	6.8	6.3	1	23	1558	1581	1558	1581	0.97
11	13	9.1	6.2e+02	1.1	3.4	1	23	1700	1723	1700	1723	0.78
12	13	0.0082	0.56	10.7	0.5	3	23	1780	1800	1778	1800	0.96
13	13	0.0013	0.089	13.2	4.8	1	23	1806	1828	1806	1828	0.99

Sequence Information

Coding Sequence: ATGCTcgccacacagcagcagcaacagcagcaacaacaacaacaatcgcacacagcagcagcagcaacacttgaGGATGCTCGCGATTTGGGCTTAATGGAGACGCGACAACGTCGCGATTCGAGTACATCTGAATCCTCGCTGGAGCATTTGGATTTGGGTCGCACGCCAAAAaagttgagcagcagcagcggggcACCGCAGCCGACGTCGACGCCGCACGACACAGCAGTGACAGCGACGTCGCGCAAGCGGAAACTGcgacagcaacaccagcagcagcagcaacagttgccgctCTCCGATGAGgaccagcatcagcagcaacagcagcagctgttggacTCTTCAGCGCAACGACCGCGTCACAAGCAGCGACGCAGCGCTATTGCTGCCGCCACCAGCGCCAGCATCGTTGTTGACTACAGCGCCAGCGGAGACGCCAGCTCGCTGCGCAAAAAGTTTCGACTGAAtcgcagcagcgccagcagcaatgCTGCCAACGGTGATTTATCCGAGTCTGGCTTCGTCGATGGCAGCGCCCTCAGTGGCTATCTgcttggcaacaacaacaacaataacaacaacaacaacaataacaataataacaacaacaacaatattagtagtagtagcagcagcagcgcagtcgCTCagtcagcagcatcagcagcagcgtcggcaGCGCAGCATGCGTCAAGCGTTAGCAGCTCGGGCGGCTCCTCGCCACAGGGCCTTTCGAGCGCCGAATCGGGCATCGGCGCCGGTGATGAGcacatgaaatatttgtgcCCCATCTGTGAGGTCGTCTCGGCCACGCCCCACGAATTCACCAATCACATTCGCTGCCACAACTACGCCAACGGCGACACCGAGAACTTCACCTGCCGCATCTGCTCCAAGGTGCTGTCGTCGGCATCCTCGCTGGACCGGCATGTCCTGGTGCACACTGGAGAGCGTCCGTTCAACTGTCGCTATTGCCACTTGAACTTCACAACCAATGGGAATATGCACCGACACATGCGCACCCACAAGCAACATCAGGcctcgcagcagcagcagcaacagcagcacagctcgcagcagcagcaatcaagccaacagcagcaacagcagcaggcacagtcgcagtcgcaacagcagcaacagcgacgccAGCAACATGTGggtggagctggagcagctggcCTCGAATCGGGATCGGGACAGTTGTTGACAACGCGAGCCGAGAGCTATGAGAGTGATGCTAGCTGCTCGACGGATGTGTCCAGTGAGCTGAACagtcacagcagcaacagcaatcaatccaaccacaacaacaatagccacaaaacgaacaacaataacaacaataagaacaacaacaacaacaacaacaacaatgaggatgagatggagctggagctggagctggaggatGAGCAGCTAGTATTGAGCAGCAAACAGCGACGCCTCAAGACAGtcctaaacaacaacaatataattaGGGATGAGGAGCACGAGAATCGGGCGGATGATGATTCGGATGTGGACAGCGTTGATAGTGTTGCCCAGGTGATAACAAGCACACCAGATGTGGCCACGTTGCTCGCCTCGGGCGGCACCTCGCCAAGTCACTCGCATTCGGAATCGCATTCAccgccactgctgctgcagagtTGCCCCGCCTGCAATTCGGGTGAATTTGAATCTGTGCCAGCGTTGTGCGCCCATCTGGATGCCGAGCATGCGGACATACCGGCCAAGTGTCGCGAATGCGAGGTGATCTTTGCCACACATCGACAGCTGCAGGCGCACAGCTGTCGTGGATTGCCGCCGCTCCTTGGTGTCAGCTCATCGCCACTGCACAAGCAGGAGGAGAACGAACTGGAGGATGAGGAGCATCAACAGAAGCAGCACGAGGAGGACCATGaacagcaacacaagcagGAGGAACGGGAGCAGGCTGAGCAGCGCGAATGTGAAGATTTCTTCCAGCAGCTGTATCTGAAGAATAAATCGTCAGCAGCGCTCCTGCCATCTCCGATCAAACATGAGCCGGCGGATCAGCGACAGGATCTGGCTGACATTCAAAGCATACTCAATATGACCAGTTCCAGCTGCACCTCGAGTTTCCTGCGCAATTTTGAGCAGTCGGTGAACACGCCCTGCTCCAGCCAATATAGCGTCGATGGACGGGATGGCGAGGAGGAGGCCCAGGATGCGTTCACCAATGAGTTCCGCAGAATGAAACTGCGCGGTGAGTTCCCCTGTAAGCTATGCACTGCCGTCTTTCCCAATCTTCGGGCACTCAAGGGCCACAACCGCTACCATCTGTCGGAGGTGGGCGCCGCTGGCCCATTCCGTTGCAACATGTGTCCCTATGCCGTCTGCGATAAGGCGGCGCTCGTGCGGCACATGCGCACCCACAACGGGGATCGGCCCTACGAGTGCGCCGTCTGCAACTATGCGTTCACCACCAAGGCGAACTGTGAGCGCCATTTGCGCAATCGACATGGAAAGACCAGTCGGGATGATGTGAAACGTGCGATTGTCTACCATCCAGCCGAGGATGCCAGCTGCGAGGAGAACAAATCCCGCACCGATGCCGATATCCTAACCGAGCTGAGCGGCTATCGCTGTCCAACGCCCACAGAGCACAGTTCCTCGGCAAGCTCCTCGTCCCAGCTAAAGCACATGTTGCTGGCGGAGCCGACACCGGCCGTAAaggtaacagcaacagcagcagcagcagcagcagcaacatcgatGCCGCAACAACCGCTCAAGATTCAGGTGAAGAGCTTGGATCAGCTGGTGGATAAGCCACTGCCTGCACTCGATCTCAGCATGGATGCGCTAGACTTGAGCAAGAAGCCCGCACAGCTGCTGGCCGAGCAAAGGGAGCAAAGGGAGCAGCTCGAAAGACACgaattgctgttgcagcagcaacagcagcagcagcagcaacagcaacaacagcagcagcagcagcagcagcaacaacaaatgtttggGGCTGGCGATGCAGCTGCTCAGTATATGCAACAGCTGTTGCGCAGCTTCATGCTCCAGCAGTCACCCGGTTTTCCTTTCTTTGGTTTTATGGCGCCACCGCCACCAACAGCGGCatcagtagcaacagcagcagacaagtcaatgccaacaaatccaacagcagcagcagcagcagcagcagcagccggcgcaacagcagcaacaattgctgcattGCCACTGTCGCTGCCCGTGCCACTGCCCGCTGGTGGTCCCGTCAAGATGGTCATCAAGAATGGCGTCCTGATGCccaagcagaagcagcgccGCTACCGCACCGAGCGTCCCTTTGCCTGCGAGCATTGCTCGGCCCGCTTCACGCTGCGCTCCAACATGGAGCGGCACgtgaagcagcagcatccacagTTCTATGCGCATCGCCAACGACACCGCAGCGGTCATCATGTGATGCGTGACCGGGCTGCATCATCCAGTGCTGTCCAAGCGGCAGCCGCTGctcaggcagcagcagcagcagcagcggccgcAGCAATGAGTAATctcaaccagcagcaacagttgcagcagcagcaacagcaacagttgcagcattCACATCACGTCCATGCGCCAATTTCGGAGCAGGTCAAATATGCCATTTTAGCGCAGCAATTGAAGGCGCGCAAGGATACGGATTTGCTGCAACAGGCACTGGCACATGGCTCCAGCAGTGTTGTCACCAATCCGCTGCTGCATTttagctacaacaacaacagcatcggcaacaagcagcagcagcagcaacagttgagCAACAACACTGGCAACTCTTTGGTGCTGGACGATGATGAGCCGCCCAAGTTGATTATTGACGAGGATGATGAGGATGTGGagggcgatggcgatggcgaggGCGATGGCGAGGGCGAGGGCGAGtgcgatgacgatgatgatgaggaggaggagcatgAATTTAATGTCGATgacgaggagcaggaggaTGAAGAGATGGACTTGGACGATgagtatcagcagcagcagctgccgcacgAGGAGgatgatgatcatgatgatgataatgatgcagcagtcgcagcagcagcagcagcagaggcgtcgctgcaacaattgcaggCAGCAAAGGACAAACTGCAATCGAAGCCAATTGAGGCGGCCAAAAAGGCAGCGGAGATCATAATCAAGGAGGGCGAGGAGAAGGCCTCCGAGAAGCAGCCGCGTTCCCAATCTCAGTCGAGAGGCGGCAATAAGCCGGCGacgccaacaacaatgaaaacaatgaTTGCACAAGCGGAATCGGTGGCGAAGTCCTTGAAGGAGGTGGCCAGTTCACCGTTCAAGGATGAATCTCAGGATCTGGTGCCTGTGGCCAAACTGGTGGACAATGCGACCAGCAATCAGGTGTCATTCAATAGCTATTTCCGTCCCAGCGACGTGGCCAATCACATGGAGCAGAGCGACGAGGAGGGTCTCGTTGCCAGCGGCAGCGCCAGCGAAAGCAACAATTCCGGCACCGAGGATgtgaccagcagcagcagcagctgcggcaacGACACCAAAAAGAAATCCGCCTACAGCCTGGCACCGAATCGTGTCAGCTGCCCGTATTGCCAGCGCATGTTCCCCTGGAGCAGCTCGCTGCGCCGCCACATCCTGACGCACACCGGCCAGAAGCCGTTCAAGTGCTCCCATTGCCCGCTGCTGTTCACCACGAAGAGCAACTGCGATCGCCATCTGCTGCGCAAGCATGGCAACGTTGAGTCCGCCATGTCTGTCTACGTGCCCACCGAGGATGTCAGCGAACCGATACCCGTGCCCAAGTCCGTCGAGGAGATTGAGCTCGAGGAGCAGCGACGTCGCCAGGTGGCCGAGGCCGAACAGGCCGAACGTGAGCAGCTCGAGCGCCAAAAGGAGCGCGAACGTGAACTGGAATTGGAACGGGAAAGGGAAcgggaacagcaacaattgatACAACAGTTGCGCCAACAAAtggccgctgctgcagcagctgttgctgttgccgttgtcacTGCACCAGCGCATCCAGCAGCACCACAGCCAGCCCAATCGCCACCGGGCCTGGAGGCGAGCAGTGATCTGCCCTACAAATGCCATCTGTGCGAATTCTCGTTTGGCGAGCGGCTGCAGTGTCTCGAGCACATCAAGCAGCTCCACTCGCACGAATTCGCACTGCTCCTGGCCAAGGGGGCCATCGAGACGGATGCACAACTGCAGCATCAACAGTTGCCAGTCGCTGGTGGCGCCTCACATTCGGATGATGAGGCTGCCGCTGTCGGCACCAGATCGGGCAAATATCCCGACTATAGCAATCGCAAAGTAATTTGCGCATTTTGCGTGCGTCGCTTCTGGTCAACGGAGGATCTGCGGCGACATATGCGCACCCATTCCGGCGAGCGTCCTTTCCAGTGCGAGATCTGCTTGAGGAAGTTCACATTGAAGCACAGCATGCTGCGGCACATGAAGAAGCACAGTGGACGCAGTCACAATGGTGGCGAACTTGATCATCAATCCGATTGTTCCGATGATGAGCAGATGTTGCCCTGCTCCCCACCCTCAACGCCAACGcccactaacaacaacaacaacaacaacaacaacacttgccagaacaacaacaacaacaatagcaacaacaataacaacaacaacaacaacaacaatagcaatagcaaacaGGTACTGCGTGAGCTGCTGGGCAAGGCAAACGAGTGGCGAGTGAGTCGCCTGGGTGAGCAGAAGGAGAACATTGccgaggcaacaacaacaccatcagcagcaacagcaacagcggcagcaacagctgcagcagcagcagcagcagcagcggcagcagcagctgtggccaGTGGCGATCTAATTGGTAATCTGTTGGGGATCAGTGATCAGGGCATACTAAACAAGCTGCTCTCCTCACCAGACGAAGCTGCCAAGCTGCTGGGAGTGGAGAAGTAA
Protein Sequence: MLATQQQQQQQQQQQSHTAAAATLEDARDLGLMETRQRRDSSTSESSLEHLDLGRTPKKLSSSSGAPQPTSTPHDTAVTATSRKRKLRQQHQQQQQQLPLSDEDQHQQQQQQLLDSSAQRPRHKQRRSAIAAATSASIVVDYSASGDASSLRKKFRLNRSSASSNAANGDLSESGFVDGSALSGYLLGNNNNNNNNNNNNNNNNNNNISSSSSSSAVAQSAASAAASAAQHASSVSSSGGSSPQGLSSAESGIGAGDEHMKYLCPICEVVSATPHEFTNHIRCHNYANGDTENFTCRICSKVLSSASSLDRHVLVHTGERPFNCRYCHLNFTTNGNMHRHMRTHKQHQASQQQQQQQHSSQQQQSSQQQQQQQAQSQSQQQQQRRQQHVGGAGAAGLESGSGQLLTTRAESYESDASCSTDVSSELNSHSSNSNQSNHNNNSHKTNNNNNNKNNNNNNNNNEDEMELELELEDEQLVLSSKQRRLKTVLNNNNIIRDEEHENRADDDSDVDSVDSVAQVITSTPDVATLLASGGTSPSHSHSESHSPPLLLQSCPACNSGEFESVPALCAHLDAEHADIPAKCRECEVIFATHRQLQAHSCRGLPPLLGVSSSPLHKQEENELEDEEHQQKQHEEDHEQQHKQEEREQAEQRECEDFFQQLYLKNKSSAALLPSPIKHEPADQRQDLADIQSILNMTSSSCTSSFLRNFEQSVNTPCSSQYSVDGRDGEEEAQDAFTNEFRRMKLRGEFPCKLCTAVFPNLRALKGHNRYHLSEVGAAGPFRCNMCPYAVCDKAALVRHMRTHNGDRPYECAVCNYAFTTKANCERHLRNRHGKTSRDDVKRAIVYHPAEDASCEENKSRTDADILTELSGYRCPTPTEHSSSASSSSQLKHMLLAEPTPAVKVTATAAAAAAATSMPQQPLKIQVKSLDQLVDKPLPALDLSMDALDLSKKPAQLLAEQREQREQLERHELLLQQQQQQQQQQQQQQQQQQQQQQMFGAGDAAAQYMQQLLRSFMLQQSPGFPFFGFMAPPPPTAASVATAADKSMPTNPTAAAAAAAAAGATAATIAALPLSLPVPLPAGGPVKMVIKNGVLMPKQKQRRYRTERPFACEHCSARFTLRSNMERHVKQQHPQFYAHRQRHRSGHHVMRDRAASSSAVQAAAAAQAAAAAAAAAAMSNLNQQQQLQQQQQQQLQHSHHVHAPISEQVKYAILAQQLKARKDTDLLQQALAHGSSSVVTNPLLHFSYNNNSIGNKQQQQQQLSNNTGNSLVLDDDEPPKLIIDEDDEDVEGDGDGEGDGEGEGECDDDDDEEEEHEFNVDDEEQEDEEMDLDDEYQQQQLPHEEDDDHDDDNDAAVAAAAAAEASLQQLQAAKDKLQSKPIEAAKKAAEIIIKEGEEKASEKQPRSQSQSRGGNKPATPTTMKTMIAQAESVAKSLKEVASSPFKDESQDLVPVAKLVDNATSNQVSFNSYFRPSDVANHMEQSDEEGLVASGSASESNNSGTEDVTSSSSSCGNDTKKKSAYSLAPNRVSCPYCQRMFPWSSSLRRHILTHTGQKPFKCSHCPLLFTTKSNCDRHLLRKHGNVESAMSVYVPTEDVSEPIPVPKSVEEIELEEQRRRQVAEAEQAEREQLERQKERERELELEREREREQQQLIQQLRQQMAAAAAAVAVAVVTAPAHPAAPQPAQSPPGLEASSDLPYKCHLCEFSFGERLQCLEHIKQLHSHEFALLLAKGAIETDAQLQHQQLPVAGGASHSDDEAAAVGTRSGKYPDYSNRKVICAFCVRRFWSTEDLRRHMRTHSGERPFQCEICLRKFTLKHSMLRHMKKHSGRSHNGGELDHQSDCSDDEQMLPCSPPSTPTPTNNNNNNNNNTCQNNNNNNSNNNNNNNNNNNSNSKQVLRELLGKANEWRVSRLGEQKENIAEATTTPSAATATAAATAAAAAAAAAAAAAVASGDLIGNLLGISDQGILNKLLSSPDEAAKLLGVEK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00535518;
90% Identity: iTF_00525357;
80% Identity: -