Basic Information

Insect: Drosophila melanosoma
Gene Symbol: Znf639
Assembly: GCA_035042045.1
Location: JAWNLY010000149.1:685332-688474[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 0.014 0.97 9.9 0.4 3 23 321 342 320 342 0.91

2 10 0.00015 0.01 16.1 0.5 6 23 351 368 351 368 0.99

3 10 9.1e-06 0.00062 20.0 0.3 1 23 374 397 374 397 0.98

4 10 0.00012 0.0085 16.4 0.5 1 23 409 431 409 431 0.98

5 10 0.0003 0.021 15.2 7.7 1 23 438 461 438 461 0.96

6 10 1.3e-05 0.00087 19.5 1.8 1 23 467 489 467 489 0.96

7 10 0.32 22 5.7 0.9 2 23 498 519 497 519 0.96

8 10 0.00012 0.0083 16.5 2.8 2 23 525 547 524 547 0.95

9 10 1.1e-06 7.5e-05 22.9 0.7 2 23 554 575 553 575 0.96

10 10 0.00019 0.013 15.8 4.4 1 23 581 604 581 604 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	0.014	0.97	9.9	0.4	3	23	321	342	320	342	0.91
2	10	0.00015	0.01	16.1	0.5	6	23	351	368	351	368	0.99
3	10	9.1e-06	0.00062	20.0	0.3	1	23	374	397	374	397	0.98
4	10	0.00012	0.0085	16.4	0.5	1	23	409	431	409	431	0.98
5	10	0.0003	0.021	15.2	7.7	1	23	438	461	438	461	0.96
6	10	1.3e-05	0.00087	19.5	1.8	1	23	467	489	467	489	0.96
7	10	0.32	22	5.7	0.9	2	23	498	519	497	519	0.96
8	10	0.00012	0.0083	16.5	2.8	2	23	525	547	524	547	0.95
9	10	1.1e-06	7.5e-05	22.9	0.7	2	23	554	575	553	575	0.96
10	10	0.00019	0.013	15.8	4.4	1	23	581	604	581	604	0.96

Sequence Information

Coding Sequence: ATGATCTGTCGCTTGTGTTTAAAAAGCATAAACGCAAACAATGCCGTCTATCTATTCGAAACAAACGACGCCCTGGCCGAATCCTCGCTGCTCAAGATAATAGCCAAGTTTCTGCAGCTGGAGATAGTGCCCGATGACAACATCTCGACGAACATTTGCCATGATTGTTGCGAACATTTGGAGGACTTTAACAACTTCTGGCAACTGGTGGAGCAAAAGCAATTAACACTTAAAAAGGAGTTCCTCAATGTGGACGTCGACTGCATGGCCCTCAAATGGACGGGCGGCATTGATGTGGATGTCAATATTGATGAGCTGCCGCTGGTCACCGACGAGATGGACGAGAAGCCACTCGATATACACAATCTCAGTCTCCTCGGCAGCGTTCTCGATGTGAATGTGGACAGTGTGGAGGTGCCGCAGATGAATGCTGCACCAAAACATTGGCACAATCCCGACCAGCTCCTGCCCCTGCACGCCTTCAATcctgacgatgatgatgatgatgacgatgaggacaAAGTCGAAGATGTCGATGAGAAGCGCATAATGAATGAGAGCAGCGATAGCACGCCGCACACTTCTTCAGATGATGATGATGAAGTGCCTCTGGTGAAGCTGAAGCACAAGCTCAAACCAAAAAGGAAAGGACGAGTTGGTGCACGCAATGAGCAGCGCCGGCTAACGCTAGCCCAGGAGCTGAATCAGCTGCTGGATGACACCGACACTGGAtgcgataacgataacgatggCGACGGCgttggcgatggcgatggagTCAATCGAGGGCGTCGCAAGCAGCGGAACACAAGCcgaaacacaaacacaaataataatgttcCAACGGGTACACAGAAAAGCGAACTGCAGGCGGCCATGGAACGAAAGCCGAAGGGCTGCTCGCGGGCGCAGCTATCGAAGCGGTATGAGGAGGCCATCGCCAGCTATATGAATGCCGACTGTGATCTGTGCGACTTCAGCACTAAGTACCTGTCTCAATTGAAGGTTCACTTCTTGGAGGTGCATCAGCGCGATGCGTATCTCAAGTGCTGCAACAAGGTCTTCAATCGCGCCTCCAAACTGATGGATCACATACGCAAGCACATCAATCCCAAGTTATTCACCTGTTCGATTTGCAACAAGTCGCTAAATTCCCAGGATTATCTGGCAACGCACATTGAGACAGTACACAACAAGGTTGCCCAGATTGGCAAGGTGCTAAAGTATCCGTGTCCGAAATGCGAGCGCACCTTCAGCAGCGAGAGGCGTTTGGGTAATCATTTGCTGAAGCACGACACGGATCAGTTGGAGCACAGTTGCCACATATGCCACAAAAGCTTTGCGAATGTGCACCGACTACGTCGGCACATACAGTCGATCCATGAGGATGTACATCCGCATGTCTGCGACATTTGTGGCAAGAAGTTCAAGTTTAAGCCATCGTTTGAGCGCCACTTGCTAGAACATCAGGGCGTCGTCGCACCAGCGATGGAGTGCTCTGTCTGTGGTGTCTGGCTGAAGAACGAACACAGTCTGCGGCTCCATCGATTTACACACGATAGCACCGATACTGTCTGTCCCCATTGCTCCAAGACGTGCAGTTCACGGACAGCGTTACGGGCTCATGTTAAATATGCTCACAAGCTGACCACAAATCTGCAGTGCACGTACTGCGAGAAGAGCTTCAAGCAGCAGCGCAACCTCGACGAGCACATGGCAATACACACCGGCCTTCAGCTATACAATTGCCCCCACTGTCCTAAGGAGTGCAGATCGCGCTCCAACATGTATGTCCACATTAAGCAGAGGCATGCTGACGAGTGGCTCAAGGCCAAAATGGCACGCTCTCACAATCCGCAGTTTAAGCCGCACGCCTAA
Protein Sequence: MICRLCLKSINANNAVYLFETNDALAESSLLKIIAKFLQLEIVPDDNISTNICHDCCEHLEDFNNFWQLVEQKQLTLKKEFLNVDVDCMALKWTGGIDVDVNIDELPLVTDEMDEKPLDIHNLSLLGSVLDVNVDSVEVPQMNAAPKHWHNPDQLLPLHAFNPDDDDDDDDEDKVEDVDEKRIMNESSDSTPHTSSDDDDEVPLVKLKHKLKPKRKGRVGARNEQRRLTLAQELNQLLDDTDTGCDNDNDGDGVGDGDGVNRGRRKQRNTSRNTNTNNNVPTGTQKSELQAAMERKPKGCSRAQLSKRYEEAIASYMNADCDLCDFSTKYLSQLKVHFLEVHQRDAYLKCCNKVFNRASKLMDHIRKHINPKLFTCSICNKSLNSQDYLATHIETVHNKVAQIGKVLKYPCPKCERTFSSERRLGNHLLKHDTDQLEHSCHICHKSFANVHRLRRHIQSIHEDVHPHVCDICGKKFKFKPSFERHLLEHQGVVAPAMECSVCGVWLKNEHSLRLHRFTHDSTDTVCPHCSKTCSSRTALRAHVKYAHKLTTNLQCTYCEKSFKQQRNLDEHMAIHTGLQLYNCPHCPKECRSRSNMYVHIKQRHADEWLKAKMARSHNPQFKPHA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00610817;
90% Identity: iTF_00553200;
80% Identity: -