Basic Information

Insect: Drosophila melanosoma
Gene Symbol: Hr39
Assembly: GCA_035042045.1
Location: JAWNLY010000194.1:2620259-2623338[-]

Transcription Factor Domain

TF Family: SF-like
Domain: zf-C4|SF-like
PFAM: AnimalTFDB
TF Group: Zinc-Coordinating Group
Description: The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 3 0.91 7.6e+03 -4.2 16.1 32 206 29 220 20 226 0.50

2 3 2 1.7e+04 -12.0 30.6 48 98 206 296 181 381 0.36

3 3 1.2e-98 1e-94 318.2 6.2 1 408 513 884 513 884 0.86

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	3	0.91	7.6e+03	-4.2	16.1	32	206	29	220	20	226	0.50
2	3	2	1.7e+04	-12.0	30.6	48	98	206	296	181	381	0.36
3	3	1.2e-98	1e-94	318.2	6.2	1	408	513	884	513	884	0.86

Sequence Information

Coding Sequence: ATGCCAAATATGTCGAGCATTAAGACGGAGCAAAGTGTTTCACCCGGTGCCAGTGGCAGCTATCAGCTGCCTGAAAACATGTCGACGGCGACAGTGATGCCAGCGTCGCAGCCgctgcaccagcagcagcagcagcagcagcagcagcgtcacaATGTCTCCGTGACGAATATCAAATGTGAACTGGACGAGCTGGCGACGCCAACGAATGGCAACCTGGTGCCGGTCATAGCCAactataataatcataatcacaatcacaatcacaatcataGCGGCAGCCTGCGCATTCCCCTCGGTGGCCATGGGGATGAGTCCGACTCGGATGCGGAGCTGGCCAACATTGAGAATCTGAAGGTGCGGCGACGTGCGGCCGACAAGAATGGTCCGCGTCCCATGTCCTGGGAGGGTGAGCTGAGCGAGAATGAAACGAATGGCGGCGCTGTCGGTGACGAGGAGGAGCTCATGGAAACGGAAACGGTGATCAAGAGTGAggtgagcagcagcaccagcagcagcagcagtgccacAACGTTGGCCGGCAGTCAAGTGAACGCCATGTTGCAGCCCATCAAAACCGAACTGGAGCACATAGCCGGTgagatgcaacagcaacaacaacagcagcagcaacaacaacaacaacaacagcagcagcaacaacaacaacatcagcagcaacagcagcagcagcagcagcaactgcaacagcaacaactgcagcagcaacaacttcagctgcaacagcaacaacaattgctgccaCTGAAGCAACAGAGCTATGCACCGAACAACAAACTGAAATTGGCGCCAACGCAAAGTGATcccatcaatttaaaatatgagccaacgacaacgacaacatcatCGCTGCTCTGCGACAGGAGCAAGTCGAATAGTGGCGGAcatttgccgctgctgcccgCCAATCCCAGTCCCGATTCTGCCATACATTCCGTCTATACGCACAGCAGCCCCTCCCAATCCCCGTTGACGTCCCGCCACGCCCCCTACACGCCATCGCTGAGCAGAAACAACAGCGATGCGTCGCACAGCAGctgctacagctacagctccGAATTCAGTCCCACCCACTCACCGATACAGGCGCGTCATGCGCCACCCGCTGGCGTTGCTGCCTTATTTACGGGCAATGGAAATGGCGGTGCACTGCATCATCATAGTGTGCTCTATCGGCCACTCAATGTGGATGCCGCACAGGAGGCGCAAAACCTGAGCATGGATGCGGGTGGTGCTGCGCTGGATGCCAGCGCCACGTTGGCCGCCTCGCCGGCGGGCATCTCGCGTCAGCAGCTGATCAATTCGCCGTGTCCGATTTGTGAGGATAAGATCAGTGGCTTCCATTATGGCATCTTCTCGTGCGAGTCGTGCAAGGGCTTCTTCAAGCGCACCGTCCAGAATCGCAAgaactatgtgtgtgtgcgcggcGGTCCCTGCCAGGTGAGCATCTCGACGCGCAAAAAGTGCCCCGCCTGCCGTTTCGAGAAGTGCCTGCAGAAGGGCATGAAATTGGAAGCGATTCGCGAGGATCGCACCCGAGGCGGTCGCTCCACTTATCAATGCTCCTACACGCTACCCAATTCAATGCTCAGTCCGCTGCTTAGTCCGGATCAGGcggcagccgccgccgcccatcagcagcaacaacaacaacagcaacaacagcaccagcagcagcaacatggtCCACTCAATGGctttggtggtggtggctcCAACTCGCTGCCAGCGAGTCCCAGTCTCGGCGGGGCATCCATCAAGACGGAGCTAGCGGAGCAGCTTAATCATCATACGTTATCATCAACGCGAGCCTCAAGCATTCCAGCCCTGCTGCAGgAAATCATGGATGTTGAACATCTCTGGCAATATACAGATGCGGAATTGGCACGCATTAATCAGCCGCTGTCCTCATTTGCAACTGGTGGCTCATCGTCGAGCGGCACAGGCGGTTCAAGTTCCGCCGGACAGCATACGGGCAATGCACAACAAATGACCAATCCACTGCTGGCCAGTGCTGGTCTCTCATCCAACGGCGAGAACGCCAATCCCGATCTGATTGCACACCTCTGCAATGTGGCCGATCATCGCCTCTACAAGATCGTCAAATGGTGCAAAAGTTTGCCGCTCTTCAAGAACATCTCGATTGACGATCAGATCTGCCTGCTCATCAACTCGTGGTGTGAACTGTTGCTCTTCTCCTGCTGTTTTCGTTCCGTCGACACGCCCGGCGAAATCAAGATGTCACAGGGCCGTAAGATTACGCTGGCACAGGCTAAAACCAATGGCTTGCAGgctTGCATTGAGCGCATGTTGAATCTGACGGATCATTTGCGTCGCCTGCGCGTGGATCGCTACGAATATGTTGCCATGAAGGTAATCGTGCTGCTGCAGTCCGACACAACGGAATTGCACGAGGCAGTCAAGGTGCGCGAGTGCCAGGAGAAGGCGCTGCAGGGTTTGCAGGCCTACACGCTAGCCCATTATCCCGATACGCCGTCCAAGTTTGGTGAGCTGCTCCTGCGCATACCCGATCTGCAGCGCACGTGTCAGCTGGGCAAGGAAATGCTGACGATCAAAACGCGTGATGGTgcagattttaatttgctgaTGGAACTGCTGCGCGGAGAACATTGA
Protein Sequence: MPNMSSIKTEQSVSPGASGSYQLPENMSTATVMPASQPLHQQQQQQQQQRHNVSVTNIKCELDELATPTNGNLVPVIANYNNHNHNHNHNHSGSLRIPLGGHGDESDSDAELANIENLKVRRRAADKNGPRPMSWEGELSENETNGGAVGDEEELMETETVIKSEVSSSTSSSSSATTLAGSQVNAMLQPIKTELEHIAGEMQQQQQQQQQQQQQQQQQQQQQHQQQQQQQQQQLQQQQLQQQQLQLQQQQQLLPLKQQSYAPNNKLKLAPTQSDPINLKYEPTTTTTSSLLCDRSKSNSGGHLPLLPANPSPDSAIHSVYTHSSPSQSPLTSRHAPYTPSLSRNNSDASHSSCYSYSSEFSPTHSPIQARHAPPAGVAALFTGNGNGGALHHHSVLYRPLNVDAAQEAQNLSMDAGGAALDASATLAASPAGISRQQLINSPCPICEDKISGFHYGIFSCESCKGFFKRTVQNRKNYVCVRGGPCQVSISTRKKCPACRFEKCLQKGMKLEAIREDRTRGGRSTYQCSYTLPNSMLSPLLSPDQAAAAAAHQQQQQQQQQQHQQQQHGPLNGFGGGGSNSLPASPSLGGASIKTELAEQLNHHTLSSTRASSIPALLQEIMDVEHLWQYTDAELARINQPLSSFATGGSSSSGTGGSSSAGQHTGNAQQMTNPLLASAGLSSNGENANPDLIAHLCNVADHRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLLFSCCFRSVDTPGEIKMSQGRKITLAQAKTNGLQACIERMLNLTDHLRRLRVDRYEYVAMKVIVLLQSDTTELHEAVKVRECQEKALQGLQAYTLAHYPDTPSKFGELLLRIPDLQRTCQLGKEMLTIKTRDGADFNLLMELLRGEH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00575636;
90% Identity: iTF_00595983;
80% Identity: iTF_00543795;