Dmel007154.1
Basic Information
- Insect
- Drosophila melanosoma
- Gene Symbol
- Bro
- Assembly
- GCA_035042045.1
- Location
- JAWNLY010000145.1:1992204-1992839[+]
Transcription Factor Domain
- TF Family
- CBF
- Domain
- CBF_beta domain
- PFAM
- PF02312
- TF Group
- Beta-Scaffold Factors
- Description
- Core binding factor (CBF) is a heterodimeric transcription factor essential for genetic regulation of hematopoiesis and osteogenesis. The beta subunit enhances DNA-binding ability of the alpha subunit in vitro, and has been show to have a structure related to the OB fold [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 1 3.2e-73 2.7e-69 232.0 1.0 1 153 35 183 35 193 0.96
Sequence Information
- Coding Sequence
- AtgcatcatcatcctcatcaaaATCTTGGAGATGCTGGCATAATGCCACCCTACGAAACAATGGCAATGTACGAACAACCCAAACCACgtttcattttcaaaatgcCGCGGGTGGTACCCGATCAAAGATCGAAATACGAGAGTGATGAACTCTTCCGGCGCCTGAGCCGCGAGAGCGAGGTGCGCTACACTGGTTATCGTGAGCGGGCGATCAATGAGCGCCGGATGCGTTTTGTGACGGACTGTCGGAAGGGCTATGCGGAGATATCGTTTGTAGTCTCAGGCACCAATGTCCAACTGTACTTCAATGTCAATCACAATCCCTACGCACAGGAGCAGGAGTGCGATTTCGACAAGGAGCGCGGCAAAGTTCACTTGCGTTCTAGCTTCATCATGAACGGGGTCTGTGTGCGTTTCCGTGGTTGGCTGGATCTGGAGCGCTTGGATGGCGTTGCGTGTCTCGAGTTCGACGAGGGACGTGCACTGGTGGAGGATGCGCAACTGTGCGAACAAATCGAAAGCCACAATCAGCGCATTAACGACTCAAAGCGCATTTATGTTCAGACGCCGCCACAGGATGTCTTGCGACATGGTTCGGGACCGGCACCGGGTTCGGGACCACCTATGGGCTGGTAA
- Protein Sequence
- MHHHPHQNLGDAGIMPPYETMAMYEQPKPRFIFKMPRVVPDQRSKYESDELFRRLSRESEVRYTGYRERAINERRMRFVTDCRKGYAEISFVVSGTNVQLYFNVNHNPYAQEQECDFDKERGKVHLRSSFIMNGVCVRFRGWLDLERLDGVACLEFDEGRALVEDAQLCEQIESHNQRINDSKRIYVQTPPQDVLRHGSGPAPGSGPPMGW
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00582027;
- 90% Identity
- iTF_00500066;
- 80% Identity
- iTF_00535074;