Dmel014648.1
Basic Information
- Insect
- Drosophila melanogaster
- Gene Symbol
- salm
- Assembly
- GCA_000001215.4
- Location
- JANZWZ010000387.1:602052-608872[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 8 1.6e-06 0.00018 22.1 1.7 1 23 303 325 303 325 0.98 2 8 2.6e-06 0.00028 21.5 1.1 1 23 331 353 331 353 0.98 3 8 1.6 1.7e+02 3.2 2.5 5 23 547 565 544 565 0.85 4 8 2.4e-08 2.6e-06 27.8 0.2 1 23 571 593 571 593 0.98 5 8 0.00072 0.079 13.8 0.9 1 23 603 625 603 625 0.98 6 8 0.036 4 8.4 0.1 2 23 826 848 826 848 0.96 7 8 7.8e-06 0.00086 19.9 5.0 1 23 993 1015 993 1015 0.96 8 8 6.2e-08 6.8e-06 26.5 0.7 1 23 1021 1043 1021 1043 0.98
Sequence Information
- Coding Sequence
- ATGTGTTCAATATTTCGCAACCGCATCAATTACCGTGGAACTGGTGGCACCAGGAGCGGCAGCGGGGAGCGGGAGAGGGACCGAGATCGGGACAGGGATCGTGATCGAGATCGGGAAAGGGACAGAGACACCCTGCTGGCCAAGGAACTGGATGCGGATAGCAATAACAATGAAACGGCCGAGGAGCGCGGCGAGGAACAGGAGCCGGAGAACAGCAACGAGGCCCTGGATCTCTCACTGATTTCGTCCGGCGGTCGGGAATCACTGCCGGGCAGTGGTCACGTGTCGCTGGAGGCTCTACAACATACCAAAGTGGCGGTGGCCCAGTTTGCGGCCACTGCGATGGCGGGAAACCACCAGTCCGCCGATCTGGCCATGGTGCAGTCCACCATCTTTAATGTGCAGCGGCAGCATCTGATGCAGCTACAGCTCATCCAACACCTGCAGAGTCAATTGAAAAGGGCCGAGGCAGCCGCCTTGGGTAGGCACTCTCACAGCGATGAGGAGGAGGAAGAGCCGGAGCCAGAGCCGGAACCTAAGAAGCAGCCCACCAATGGCCTGAAGGAGGAGTTGGAGCTGGAGCAGGGTCCGGAGTCAGAGCAGGATCATGAGTCGCGGCGGGAGGAGAATTCAAAGACTGACAAGAGGGGAACTGAGGACAGAAAGGCAGAGCCAGAGGGTTACCAATCGATGATGTGCGACATAAGCTCGAGTCTGGCATCGAGCATTATCACCAACCACGATCCCCCGCCAGCCCCCAACGAGCCCAATTGCCTGGAGATGTTGCAACGGAGAACGGAGGAGGTCCTCGACTCCGCATCCCAGAGCTTACACGCTGCTCAGATGCAAGAGGAATACTCGGAGTATGCCTCCAAAGAGGCTCAAAGTCGCGGTGAGATCTTTAAGCATCGCTGCAAGTACTGTGGCAAGATCTTTGGCAGCTACTCGGCCCTGCAGATACATCTGAGATCACATACCGGTGAACGCCCATTCGTTTGTAATGTTTGCGGAAGTAAATTCACCACGAAAGGCAATCTGAAGGTTCACTACCAGCGGCATACGCAAATCTTTCCGCCAATGCTTCTGCCACCAGGAGTGGCGCCCAACGTGGGTCATTCGGCACCTGTGGGTCAGGAACAGCATCAGAATCAAGTTGAGGAGCCGGAGGAGATTAGACAGGAGATTCCAGTTCCGCAGGCAGAAGATCTCAGCAAGCCAATGGTTAAGGAAAAGGAGAAATCCCACTCGCCCGTGGAGCGTGTCAAGACTCCCAAAGAAGTCAAGACAGATGCATCGCTGCCGTCATCAGAGAAGCCTGAAAAAGAGATCTCCAAGCCGGTGGTGACCTCGTCACGACGAAATGGATCTGTGCGGAAGCGACAAACAAGTGCTGTTAGCCCGCCGCAAGAGGATAGGGAACGGGATCTTGTCGAGCACTTGCACATAGCCAAGCTGGTGAGACGCTCCTCTGCCAGCAGAGAATCACAGCCGGCGGAGTACTCGCTCGCGCAAATGGAGCGCATTATCGACAAGTCATGGGAGGATCTGATTGAGATCGACAAGACTTCGGAGACCTCGAAGCTGCAACAGTTGGTGGACAACATCGAGAACAAGCTgaccgatcctaaccagtgcatcttctgccagaaggttatgtcctgtcgcagttccctgcaaatgcatattcgcacccacaccggagagcgtccgttccgttgcaagatctgcggcagggctttcgccacgaagggcaatcttaaagcccacatgagcatacacaagatcaagccgccgatgaggagtcagttcaagtgtccggtgtgccatcagaagttctccaacggcatcatcctgcagcagcacattcgcatccacaccATGGACGATGGCAGCGGTGGTCAGGAGCCCCTGCCGCCAATCCTGGCGAGGCCGAACGGCTGGTCCCTGGGCACTTCGGATACATTGGATTTCTCCACCACCATATCGGATCACTCGGGTCAAAGATCTGAGTCCTCGCAAGGCGGAGATTTTGATGAGTTTATGACCATGGACAGCACGGATGACTCCAGGGATAACTCAAGTGCAGCCACAGCTACGCCTCATCCTCTAGAAAGAGAGAGGGATAGGGAGAAGGAGCGGGAGAGAAGGATTCCCAACGATTGCTCTGATGAGAGATCCCACTCCAATCCTGATTTAACTGGAGGCCGCAGCGAGAGTGGCGAAATGCCCGCCATGGATCTCTCTTCACCCTCTTCCAACTCGGGTCGTATCTTCGCAACTGGACTGGCTAACGGAGCTGCTGGTGGAGGATCTGGAAATGGTGGTCTTCCCATGCTCGGAATGCCCATGCCTCCAAATCTTCTGCTCATGGCAGCTGCTCGCGAAGAAATGCACGCTCTAGGTCATGCTCACGCCAAATTTCCCCTGCTGCCCTTTGGTCCACTTGGATTTATGGGTCTGCATCCGCCCCCAAATGTGTGCAATCTCTGCTTTAAGATGCTGCCCAGTTTGGCCGCCTTGGAGAGTCATTTGCAGAGCGAACATGCCAAAGAACCGGCGACGGGCCACGCCCAACGCCCACACTGCAGCGATGCTGGATCGCCGTATGGAGCAAAGCTCACTCTCAATCCAAATCTGTTCGCAAAGAAGCCGCCTTCGTCGTCGTCCTCGTCGTCGGGTGAAAAGTTGCCGGAGTCATCCAATCCGCCCTTTCCCGCTGAAAATCCCCCAGCAACGCCCATCAAAGAGGATCCCGATCAGGAGCAGTTGATGGTGGAGGAGGGTGCTTCGGCTGGAGAAGGATCTGGCACCGGAGCCAGCTCGAATTATCCCCAGGAGGCCGGTGATGCCGAGCAGTCCCTGATGAAGATGCAGCTCCATGCCCATCGTTTTCCTGCCAGTCCCCTCGACTTTCAGCAGGCTCTGATGTCCGCAGGACCACCGACTTCTAGTTTGGATCcgccggtgaataacaagcacttttgccacgtctgccggaggaacttcagttcgagttccgctctccagatccacatgcgcacccacacgggcgataagcccttccagtgcaatgtgtgccagaaggctttcaccaccaaggggaatctcaagGTCCATATGGGTACTCACATGTGGACGAATCCGACTTCGCGGCGGGGTCGTCGAATGTCCTTGAGCTACCCATGCGACCTGGTCCAAACTCCGGCCAAGGTCATCCTGGATCCAACGACCAGAGCTCTTTTTCCCTACCTGCCGCCCTTCTTTAACGGATTGCCACCAAAGCCTGGGGAACTCAGTCCCGGCGCCTTTCCCAATATTCCCCGCCTCCTTTGCCAACGGCGGAAGTATCCCTATCCGCCCGGGCTCCTTGGCTTCCCTGGTTTCCTGGCCCAACATCCTTACGGCCTAGAGCGGAGGAGCAGCAGCAAGTCACCCACGCCAGAGCCGGCTCAGAGTCCCGCCTTGCGGGAGGAGGAGGGGTCCGGCAATATCTGGCATCCACTGAGTCGCATCAAGGTGGAGAACAATCAAAACGAGTCCATGGGTGGCTTTAACGAGCAGGAGGATCACGCTGAGACGGATGCCACTGGAGGGGACAACGGCGAATCGGAGTCCAGGGATGCGGAGAAGTAA
- Protein Sequence
- MCSIFRNRINYRGTGGTRSGSGERERDRDRDRDRDRDRERDRDTLLAKELDADSNNNETAEERGEEQEPENSNEALDLSLISSGGRESLPGSGHVSLEALQHTKVAVAQFAATAMAGNHQSADLAMVQSTIFNVQRQHLMQLQLIQHLQSQLKRAEAAALGRHSHSDEEEEEPEPEPEPKKQPTNGLKEELELEQGPESEQDHESRREENSKTDKRGTEDRKAEPEGYQSMMCDISSSLASSIITNHDPPPAPNEPNCLEMLQRRTEEVLDSASQSLHAAQMQEEYSEYASKEAQSRGEIFKHRCKYCGKIFGSYSALQIHLRSHTGERPFVCNVCGSKFTTKGNLKVHYQRHTQIFPPMLLPPGVAPNVGHSAPVGQEQHQNQVEEPEEIRQEIPVPQAEDLSKPMVKEKEKSHSPVERVKTPKEVKTDASLPSSEKPEKEISKPVVTSSRRNGSVRKRQTSAVSPPQEDRERDLVEHLHIAKLVRRSSASRESQPAEYSLAQMERIIDKSWEDLIEIDKTSETSKLQQLVDNIENKLTDPNQCIFCQKVMSCRSSLQMHIRTHTGERPFRCKICGRAFATKGNLKAHMSIHKIKPPMRSQFKCPVCHQKFSNGIILQQHIRIHTMDDGSGGQEPLPPILARPNGWSLGTSDTLDFSTTISDHSGQRSESSQGGDFDEFMTMDSTDDSRDNSSAATATPHPLERERDREKERERRIPNDCSDERSHSNPDLTGGRSESGEMPAMDLSSPSSNSGRIFATGLANGAAGGGSGNGGLPMLGMPMPPNLLLMAAAREEMHALGHAHAKFPLLPFGPLGFMGLHPPPNVCNLCFKMLPSLAALESHLQSEHAKEPATGHAQRPHCSDAGSPYGAKLTLNPNLFAKKPPSSSSSSSGEKLPESSNPPFPAENPPATPIKEDPDQEQLMVEEGASAGEGSGTGASSNYPQEAGDAEQSLMKMQLHAHRFPASPLDFQQALMSAGPPTSSLDPPVNNKHFCHVCRRNFSSSSALQIHMRTHTGDKPFQCNVCQKAFTTKGNLKVHMGTHMWTNPTSRRGRRMSLSYPCDLVQTPAKVILDPTTRALFPYLPPFFNGLPPKPGELSPGAFPNIPRLLCQRRKYPYPPGLLGFPGFLAQHPYGLERRSSSKSPTPEPAQSPALREEEGSGNIWHPLSRIKVENNQNESMGGFNEQEDHAETDATGGDNGESESRDAEK
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00581703; iTF_00536940; iTF_00539816; iTF_00592547; iTF_00596811; iTF_00602781;
- 90% Identity
- -
- 80% Identity
- -