Dmel001208.1
Basic Information
- Insect
- Drosophila melanogaster
- Gene Symbol
- Unr
- Assembly
- GCA_000001215.4
- Location
- JANZWZ010000667.1:646155-649890[+]
Transcription Factor Domain
- TF Family
- CSD
- Domain
- CSD domain
- PFAM
- PF00313
- TF Group
- Beta-Scaffold Factors
- Description
- In molecular biology, the cold-shock domain (CSD) is a protein domain of about 70 amino acids which has been found in prokaryotic and eukaryotic DNA-binding proteins. When Escherichia coli is exposed to a temperature drop from 37 to 10 degrees Celsius, a 4–5 hour lag phase occurs, after which growth is resumed at a reduced rate.During the lag phase, the expression of around 13 proteins, which contain cold shock domains is increased 2–10 fold. These so-called 'cold shock' proteins are thought to help the cell to survive in temperatures lower than optimum growth temperature, by contrast with heat shock proteins, which help the cell to survive in temperatures greater than the optimum, possibly by condensation of the chromosome and organisation of the prokaryotic nucleoid.
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 9 8.7e-16 3.9e-12 46.2 0.0 2 65 177 239 176 240 0.95 2 9 0.00014 0.61 10.3 0.0 8 58 268 318 264 326 0.82 3 9 1e-15 4.6e-12 45.9 0.0 2 54 336 384 335 402 0.92 4 9 1.4 6.4e+03 -2.6 0.0 40 53 448 461 444 474 0.74 5 9 3.9e-12 1.7e-08 34.5 0.0 2 54 489 538 488 554 0.92 6 9 0.047 2.1e+02 2.2 0.0 45 65 596 618 583 619 0.86 7 9 9e-13 4e-09 36.5 0.0 2 55 710 760 709 771 0.90 8 9 0.061 2.7e+02 1.8 0.0 39 56 840 857 832 865 0.78 9 9 1.1e-13 4.8e-10 39.5 0.5 3 65 870 932 868 933 0.86
Sequence Information
- Coding Sequence
- ATGAATACCCAATCGAAGGTGTACCGTACCGGCGAAGAAATCTATGACAACTTGCCATGCGATAGTTATTTCAACATGAATGCCATTCGCAACCTGGGAATCCcaacaacgtttccgaccattggaacatttacacttgactctactacgttgggactgcagccgcagggtcagggcccgtcgccccagcagcagcagcatcaacaacaacaacaacagcagcagcagcagcaacatcagcagaatatgcaccaccatcaacatcagcagcaacacatgcagcagcagcagcaacatcaacaacaacagcaacatcagcagcagcagcagcagcaacaacagcatccaaccattggaatgttcgatgccaacgaggTTAACGATGTCATCCAGAATCCTCCTCAAATCGGGGTATTCCAGTCTAACAGCGTTCTGACCAACGGTGCCGGCAGTGGCTCCTCGATCTTTGGCTCCCAATCGAGCAATTCATCGGCGGCAGCTGCAGATCCCAGCCAGACCACCCGGGAAACTGGCATCATTGAAAAGTTGTTGCATTCGTATGGATTCATTCAGTGCTGTGAGCGGCAGGCGCGTCTTTTCTTTCATTTCTCGCAATTCAGCGGTAATATTGATCATTTGAAAATCGGAGATCCCGTGGAGTTTGAGATGACCTATGATCGCCGCACCGGCAAGCCGATAGCTAGTCAAGTATCAAAAATAGCCCCAGAGGTTGTTCTCTCCGAGGAGCGGGTCACCGGCACGGTGACCACCGAGCTGCGCACCGATAGCGCCAACAATGTGCTTAACTCCAGCGAGACCACAGGTCGCATAAGCTATGAGAACCGAGGCGAATGCTTCTTTTTACCCTATACCAAAGACGATGTGGAAGGTAATGTCAACTTGCGCGCTGGCGACAAGGTCAGCTTTCAAATCGCAACGAACCAAAGAGGTAATCTAGGCGCCTGCCATATTCGCCTGGAAAATCCGGCCCAGCCGGTTAAGTATCGTGGGGTTGTCTGCTCGATGAAGGAGTCGTTTGGCTTTATCGAACGTGCCGATGTGGTCAAGGAGATTTTCTTCCACTTCTCAGAGGCTGAGGGCAATGTTGAGCTGCGTCCCGGTGACGATGTCGAGTTCACCATCCAGACGCGGAGCTCTGCATCTGTGCCTCCGCAGGGCCGTGAATTTGCGTGCAACATCACGCGCCTAGCTCCGGGATCAGTGATCTTTGAGGACGTCGATAGCACGGTGTATAAGGGCCAGGTGCTTAAGTCGCTTGATCGCAACAACCCGGTGCGCCAGAACAATGATCCCTTGCCGGGTCGATCAAAGGGTGACTTCACCCTGCGCCACGGCGATTGGGTGCAGTTCCTGCTTGCCACCGATCGGCGTGATCAATTGCAGAGGGCCACCTCCATTGCCCTGTTGGACGAGACTTTCAAGGTTTCCGGCGAGAAGCGGGAGCAGGGCACCATTGCCTCTCTCAAGGAGGGCTTCGGATTCCTGCGCTGCGTAGAGCGTCAGGCTCGTTTATTTTTCCACTTTACTGAAGTTTTAGATACGAGCCGCGAAATCGATATCAATGATGAGGTAGAATTCACTGTCATTCAGGAGCCTGGATTGGCCTATAATAACTCGCGTTTGCAGGCCATTCGCATTAAACACTTGCCGCCCAACTCAGTGCAATTTGAAACTCTAGTGGCCAGCAACATAGAAGGATGTGTAACTCGCGAGGCGCCTAAGAGCCCAATTAAATCTCAAGATCGCGTCGAGGGCGGTGATTGGGAGCGCGTACGCTTCGATATTTACATGGTCAAACGTAACAAGGAGTGTAtagccgtcaacgtacagcaagtatccctgcatcagcagcaacaacagcagcaacagcagttgcatcttaatcagtcgaatgctggggcaaatatcaaccaaaatgaccagctgggaggattgtcgaatggaatcagtagcagcagcTCGAATGCTTCGCTACAGAATGGCTATGTCATGCACGGCAGCCCTGGCGGCAGCACCAGCAGCGTGGGCAGCAACAATCCGGTTCATCTGGATGAATTCAAGATGGAGAACAACAACCATGCCGGATCCGATGCCGGTCAGGTGTACCGTGGCTTCATAGCCGTTATGAAGGAGAACTTTGGATTCATTGAGACTTTGTCCCACGATGAGGAGGTCTTCTTTCACTTTAGCAACTATATGGGCAATCCCAATTGGTTGGAGCTGGGTCAGGAGGTGGAGTACACTCTTGCTCGTAATGGGAATACATCCGTTTCTGGAAACTGTCTGCCTGCGGAAAATGTCCGTATGCTGCCAAAGAACTCTATTCCCCAGCCGGCTGTGCTGGAAACCACACACAATGGCGTGGTAGCACGTCCACTGCGTTGCATCAATCCCGACCAGCAGGAATATGCCGGTCTCATTGAAATTCTCGATGAGCTACGTACCACTGTCATTTCGCAACACGAATTCGGGATTACTAGTCTGGTGAACAAGAGGGATCTGCTCCAGAAGGGCGATCTCGTTAGCTTCCGCATCGATGAGAGTGGTCGAGCAGCATGCGTGAATGCCGTAAGGCAAAAGAAGCGTGCCACAGTGGACTCCATCAAGGGTCAGTTTGGTTTTCTCAACTTTGAGGTGGAGGACGGCAAAAAACTGTTCTTCCACATGTCTGAGGTGCAGGGCAATACTGTCGCTTTACATCCAGGCGACACCGTGGAGTTCTCCGTGGTCACCAATCAGCGCAATGGAAAGTCGTCGGCTTGCAATGTTCTGAAAATAAACGATCGTCCGGATCGTCTGATCTCGCGCCTTAAGCTCAACGGCGATGACACTGTGCCGCGACTGATCCTCATTCGCGCACCCAAGGGACCGCAGGGCAAGGGCTTTTCCGTTCTAGCTCGTCATCCACGCATTCCAGGCAACTTGGTGGAGTAG
- Protein Sequence
- MNTQSKVYRTGEEIYDNLPCDSYFNMNAIRNLGIPTTFPTIGTFTLDSTTLGLQPQGQGPSPQQQQHQQQQQQQQQQQHQQNMHHHQHQQQHMQQQQQHQQQQQHQQQQQQQQQHPTIGMFDANEVNDVIQNPPQIGVFQSNSVLTNGAGSGSSIFGSQSSNSSAAAADPSQTTRETGIIEKLLHSYGFIQCCERQARLFFHFSQFSGNIDHLKIGDPVEFEMTYDRRTGKPIASQVSKIAPEVVLSEERVTGTVTTELRTDSANNVLNSSETTGRISYENRGECFFLPYTKDDVEGNVNLRAGDKVSFQIATNQRGNLGACHIRLENPAQPVKYRGVVCSMKESFGFIERADVVKEIFFHFSEAEGNVELRPGDDVEFTIQTRSSASVPPQGREFACNITRLAPGSVIFEDVDSTVYKGQVLKSLDRNNPVRQNNDPLPGRSKGDFTLRHGDWVQFLLATDRRDQLQRATSIALLDETFKVSGEKREQGTIASLKEGFGFLRCVERQARLFFHFTEVLDTSREIDINDEVEFTVIQEPGLAYNNSRLQAIRIKHLPPNSVQFETLVASNIEGCVTREAPKSPIKSQDRVEGGDWERVRFDIYMVKRNKECIAVNVQQVSLHQQQQQQQQQLHLNQSNAGANINQNDQLGGLSNGISSSSSNASLQNGYVMHGSPGGSTSSVGSNNPVHLDEFKMENNNHAGSDAGQVYRGFIAVMKENFGFIETLSHDEEVFFHFSNYMGNPNWLELGQEVEYTLARNGNTSVSGNCLPAENVRMLPKNSIPQPAVLETTHNGVVARPLRCINPDQQEYAGLIEILDELRTTVISQHEFGITSLVNKRDLLQKGDLVSFRIDESGRAACVNAVRQKKRATVDSIKGQFGFLNFEVEDGKKLFFHMSEVQGNTVALHPGDTVEFSVVTNQRNGKSSACNVLKINDRPDRLISRLKLNGDDTVPRLILIRAPKGPQGKGFSVLARHPRIPGNLVE
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00520393;
- 90% Identity
- -
- 80% Identity
- -