Dmea014400.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila melanica
Gene Symbol
Hr39
Assembly
GCA_004143765.1
Location
SCDT01000952.1:6628-11196[-]

Transcription Factor Domain

TF Family
SF-like
Domain
zf-C4|SF-like
PFAM
AnimalTFDB
TF Group
Zinc-Coordinating Group
Description
The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 4 1.5 1.5e+04 -4.9 1.2 138 163 11 36 4 67 0.65
2 4 2 2e+04 -10.5 29.8 31 153 203 330 183 359 0.38
3 4 0.39 4e+03 -3.0 4.8 52 128 310 388 294 438 0.67
4 4 3.6e-98 3.6e-94 316.7 19.5 1 408 506 903 506 903 0.84

Sequence Information

Coding Sequence
aTGCCCAACATGTCGAGCATTAAGACGGAGCAGAGCGTTTCTCCAACTggtgccagcggcagcagctatCAGCTGCCGGTGAACATgtcgacgacggcgacggcgacgacgacgctgacaacagcagcaacggggACGGGGACGGGGACGGGCACCGTGCGCGGCCACAATGTGTCCGTGACGAACATCAAGTGCGAGCTGGAGGAGCTGCCGACGCCGAACGGCAACCTGGTGCCTGTTATAGCCAactataataatcataatcacaatcacaatcatAATCacagcggcaacggcggcgccAGTTTGCGGATACCGTTGGGCGGCGGCAAAGAGGACGAGTCCGATTCGGAGGCGGAGCTGGCCAACATTGAGAATCTAAAGGTGCGCAGACGGGCGGCCGACAAGAACGGGCCGCGACCCATGTCCTGGGAGGGTGAGCTCAGCGAGCCGGAGACGAACCACGGCGAGGAGCTGATGGAAACGGAGACGGTGATCAAAAGCGAGATCAGCAACGGCGCCGCAACAGCGATGCTGCACCCGATCAAGACCGAACTGGAGCACATAGCCGGCgagatgcaacagcagcaacagcagcagcagcagcaacaacagcagcagcagcagcagcaacaacagcagcagcagcaacagcagcaactgttgcatcagcagcaacagcagctgcagcaacaacaacaacaacatcagcaactgcaactgcagccaatCAAGCAACAAAACTTTGCGCCcaacaaactgaaactggCGCCGACGCAAAGCGATCCCATCAATCTGAAGTACGAGCCGACGACGTCGTCGCTCTGCGAGCGGAGCAAGTCGAGCAGCGGCGGtcatttgccgctgctgccggccAATCCCAGTCCCGATTCTGCCATACATTCCGTTTACACGCACAGCAGcccgtcgcagtcgccgctgACGTCGCGGCACGCCCCCTACACGCCCTCGCTGAGCAGGAACAACAGCGACGCCTCGCACAGCAGCTGCTACAGCTACAGTTCCGAGTTCAGTCCCACCCACTCGCCCATACAGGCGCGCCACGCCCCGCCCGCCGGCACAGCCCTGTTTCCGGGCAATGGCACGACGGCGAACGGAACGGTGGCCACCACGGTGGCTGCACTGCATCACCACAGCGTGCTGTACCGGCCGCTGAATGTGGACGCCTCTGTTAACGCCGGGCAGGAGGCGCAAAATCTCAGCATGGATGCGACACCGTTGGATGCATCCTCGACGCTGCCCGCCTCGCCGGCGGGCATTTCGCGGCAGCAGCTGATCAACTCGCCGTGCCCGATCTGCGGCGACAAGATCAGCGGCTTCCACTACGGCATCTTCTCCTGCGAGTCGTGCAAGGGCTTCTTCAAGCGCACCGTGCAGAACCGCAAGAACTACGTCTGTGTGCGCGGCGGCCCCTGCCAGGTGAGCATCTCCACGCGGAAAAAGTGCCCCGCCTGCCGGTTCGAGAAGTGCCTGCAGAAGGGCATGAAGCTGGAGGCGATACGCGAGGATCGAACACGCGGCGGCCGTTCGACGTATCAGTGCTCCTATACGCTGCCCAACTCGATGCTCAGTCCGCTGCTCAGTCCGGATCAGGCGGCtgttgccgcagcagccgccgccgttgccaatCAGCAAcaggtgcaacagcaacagcagcaacaccaacaacagcagcagcagcaacatcaacaacaacaacagcagcagcatcaacagcagcaacagcgattgcatcagcaacagcaacaacatcatcaacatcaacacgGTTCACTTAACGGCTTTGGCGGCGGTGGCTCCAATTCACTGCCGGCCAGCCCCAGTCTCGGCGGCGCATCCATCAAAACGGAGCAGGCGGAGCCGCTAAACCATCGCATTCCAGCCCTGCTGCAGGAAATCATGGATGTGGAGCATCTCTGGCAATATACCGATGCGGAATTGGCGCGCATCAATCAGCCGCTGTCCTCATTCGCATCTGGCGGCTCCTCAACGGGCGCCGCGGGCGGTTCGAGTTCCGCCGGACAGCACACTGCGAATGCACAACAGATGACCAATCCACTGCTGGCCAGTGCCGGTCTCTCCTCCAACGGCGAGAACGCCAATCCCGATCTGATCGCGCACCTCTGCAATGTGGCCGATCATCGGCTCTACAAGATCGTCAAATGGTGCAAAAGTTTGCCGCTCTTCAAGAACATATCGATTGACGATCAGATCTGCCTGCTCATCAACTCGTGGTGTGAACTGCTGCTCTTCTCCTGCTGTTTTCGTTCCATCGATACGCCTGGCGAGATCAAAATGTCGCAGGGCAGAAAAATAACCCTGGCACAGGCGAAAACCAACGGACTACAGGCTTGCATTGAACGCATGCTCAATCTGACTGATCACCTGCGACGGCTGCGTGTTGATCGCTACGAATATGTTGCCATGAAGGTGattgtgctgctgcagtcCGATACGACGGAATTGCATGAGGCGGTGAAGGTGCGCGAATGCCAGGAGAAGGCGCTGCAGGGCTTGCAGGCGTACACGCTGGCCCATTATCCCGATACGCCGTCCAAATTTggtgagctgctgctgcgcataCCCGATCTGCAGCGCACGTGTCAGCTGGGCAAGGAAATGCTGACGATCAAGACGCGCGATGGCGCCGATTTCAATTTGCTGATGGAGCTGCTGCGCGGAGAGCATTGA
Protein Sequence
MPNMSSIKTEQSVSPTGASGSSYQLPVNMSTTATATTTLTTAATGTGTGTGTVRGHNVSVTNIKCELEELPTPNGNLVPVIANYNNHNHNHNHNHSGNGGASLRIPLGGGKEDESDSEAELANIENLKVRRRAADKNGPRPMSWEGELSEPETNHGEELMETETVIKSEISNGAATAMLHPIKTELEHIAGEMQQQQQQQQQQQQQQQQQQQQQQQQQQQLLHQQQQQLQQQQQQHQQLQLQPIKQQNFAPNKLKLAPTQSDPINLKYEPTTSSLCERSKSSSGGHLPLLPANPSPDSAIHSVYTHSSPSQSPLTSRHAPYTPSLSRNNSDASHSSCYSYSSEFSPTHSPIQARHAPPAGTALFPGNGTTANGTVATTVAALHHHSVLYRPLNVDASVNAGQEAQNLSMDATPLDASSTLPASPAGISRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYVCVRGGPCQVSISTRKKCPACRFEKCLQKGMKLEAIREDRTRGGRSTYQCSYTLPNSMLSPLLSPDQAAVAAAAAAVANQQQVQQQQQQHQQQQQQQHQQQQQQQHQQQQQRLHQQQQQHHQHQHGSLNGFGGGGSNSLPASPSLGGASIKTEQAEPLNHRIPALLQEIMDVEHLWQYTDAELARINQPLSSFASGGSSTGAAGGSSSAGQHTANAQQMTNPLLASAGLSSNGENANPDLIAHLCNVADHRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLLFSCCFRSIDTPGEIKMSQGRKITLAQAKTNGLQACIERMLNLTDHLRRLRVDRYEYVAMKVIVLLQSDTTELHEAVKVRECQEKALQGLQAYTLAHYPDTPSKFGELLLRIPDLQRTCQLGKEMLTIKTRDGADFNLLMELLRGEH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00575636;
90% Identity
-
80% Identity
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