Basic Information

Insect: Drosophila mayaguana
Gene Symbol: ush
Assembly: GCA_037075325.1
Location: JBAMCG010000068.1:12768973-12775223[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.0067 0.46 11.1 0.0 1 20 205 224 205 226 0.90

2 9 0.00029 0.02 15.4 0.8 1 23 282 304 282 304 0.98

3 9 0.052 3.5 8.3 1.0 2 21 348 367 348 368 0.92

4 9 0.05 3.4 8.3 2.9 2 21 745 764 744 765 0.93

5 9 0.0093 0.63 10.6 0.0 3 21 813 831 811 832 0.91

6 9 0.0067 0.46 11.1 0.0 2 23 892 913 891 913 0.98

7 9 0.0039 0.27 11.8 1.3 1 23 919 941 919 941 0.99

8 9 0.0014 0.094 13.2 1.9 1 23 999 1022 999 1022 0.96

9 9 0.31 21 5.8 0.7 2 20 1127 1145 1126 1147 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.0067	0.46	11.1	0.0	1	20	205	224	205	226	0.90
2	9	0.00029	0.02	15.4	0.8	1	23	282	304	282	304	0.98
3	9	0.052	3.5	8.3	1.0	2	21	348	367	348	368	0.92
4	9	0.05	3.4	8.3	2.9	2	21	745	764	744	765	0.93
5	9	0.0093	0.63	10.6	0.0	3	21	813	831	811	832	0.91
6	9	0.0067	0.46	11.1	0.0	2	23	892	913	891	913	0.98
7	9	0.0039	0.27	11.8	1.3	1	23	919	941	919	941	0.99
8	9	0.0014	0.094	13.2	1.9	1	23	999	1022	999	1022	0.96
9	9	0.31	21	5.8	0.7	2	20	1127	1145	1126	1147	0.91

Sequence Information

Coding Sequence: ATGGCTGCATACAAcgcccaccagcagcagcagcagcagcagcagcaacagcagcaacatcggcAAGAGCGTCAACAATGCTGGCCAAATTCCAAAGATTTGGGCGCACACGAGTTGAGCGAGGAGAAACAGCAGCTGGACGAGCTGCCCGAGgacgagcagctggagcagcacgCTAGCAACGCCTCtgagcagctggaggagacCGACATGGATCAGGAAATGgtcgagcaggagcaggcagcGTTCCAGGAGGCCAGTGCGCAACAGCAGGATGTGGCCGATAGCTCGACGACTCCACCGCGTAGTCCCACGCCTCCTGAGCTGGTGCCCAAACTGGAGCGTGCCGATTCGCCAGCAACACCGCCTTCTGTGGCCGCCACGCCCAGTCCGCCGCCAACGCCCACGCCGCCGCCGGCGTTGCCCAAGCTGCGTCTCAATGCGCTGCTCGCTTCCGATCCGGCTCTGAAACCCGATGCCAAGGAACTTAATCTCGAACCACGCTTGCTCGGTCCGCCGCCACAACTGGCCAAacccgagcagcagcagcagcagcagcagaatttGCCCGATCCCAGCAGTCTGGTGGAGCCGCTGCTCAAGCCGGCGCGCTTCATGTGCCTGCCCTGCGGCATAGCCTTCAGCTCGCCCTCGACGCTGGAGGCGCACCAGGCCTACTACTGCTCGCATCGCAACAAGGATGCCGACGAGGAGTCGGCCGCCGTGGACAAggccacagccgcagctgtcggcggcggcggcaatccgaatgccaacagcagctccaGTGGCGGCAGCTCCGGCTCGGAGCCACCCGCCAAGGTGGCGCGCACGGGCAAGCAGTACGCCTGCACGCAGTGCTCCTACAGCGCCGACAAGAAGGTCTCCCTCAACCGGCACATGCGCATGCACCAGACCTCGCCCGCCGCGCCCACCCTCAACAGCCTCTCCGGGCTGGCGGCCAACGGTGtggttgctgccgccgccgctacCGCTGCGGCCAGTGCGCTCGAGGAGACCTCTAGTCAACAAATCGATCGCTACTGCAGCGACTGTGATATCCGCTTCAACAACATCAAGACCTATCGCGCCCATAAGCAGCACTACTGCAGCTCCCGGCGCAGCGATGGCCAGCTGACGCCCAAGCCGGAGGcgaacgccagcagcagcaccggaGGCTCTGCAGCAGGAGTTGCGGCAGGAGGTGCTAAACACAGTGGAGCTCACAGTCCGCAGACGCGCAACAAGACGCCGACTCCTGCAATGgtcgctgctgcggcggccgctgctgcagctgccgcctcGCTGCAGGTGGCACCGCCGCAACCCTTCCTGGCACTGCCCACCAATCCCATCATCATAGTGCCCTGCTCGCTTATACGCGCCGCCAGCCTCATTCCCGGACCCCTCACCACCTCCACGTCGGGCATTGTCAATCCGGAGTCCACATGCTTCACCCTTGACAATGGCGCCCTCAAGCCACTGGCCACGGCGCTCAATATAAATGCGCTAGCCggcaatgccacgcccacgcccacgggCACGCCCATGCCTAGCAGCAATCAGCTGAGCATGCCCGTCCCGGAACCAGAGCGTCCCAGCGTCAGCAATGTCCCGGAGACTGAGACCAAGAGCAGCCCGCCAGAGCCCAAACGTAAGGAGGCCAGTGGCATGCGCGATACCACGCCCCTAGACCTATCCTTACGTCGCTCGCCCATTTCGCCGCTTTTGCAGCGCCAGCGCCTGATGGAGGAGGCGCTGCTCAGCGTCGGCAAGGAGAACCTGGAGAGCAGCAGCCGAACCGGCGGCAGCGTGACGCCGGAGCAGATAGTGTGCGCGCCCTCGCTGCCCAGCAGCCCCTCGATGAGTCCGTCGCCCAAGCGACGTGCGATCAGTCCGCGCAGTTCCGGTGCGGGCAGCGCTGCCTCGATGTCGCCGCCAGCGTTGGCAGTGCCCCATCTGCTGGACAATTTGCAGCCGTTGCGCTCCATGCTGCCCGGCGATTTTGCGCTATCCGAATCGCTGCTGGCCAAGACCAATCCGGAGCTGGCGCTCAagctggctgctgccgctgcagcagctgtggcgggcagcagtagcagcgccGAGCTGGCCAGCAAGCTTGGCTTCAGTCCAGTCCCGTCCGGCGCTGCCCCTCCCCCGGCCGTGGGCACTGTTGCAGCCAATGCGCCCAATAGCCAGCCGCAGATCTATGTCAAGCAGGGCGTGTCCAAGTGCAAGGAGTGCAACATAGTGTTCTGCAAGTACGAGAACTACTTGGCGCACAAGCAGCACTACTGCTCCGCACGCAACCAGGATGCGGGTGTGGATGGTGACTCCAAGAACGCAGTGACACCGCCCGCCGCAGTGGGCCCCGGCGTGACTGCTGGCGCATCCTCCTTGGAGACGACGCCCGTGGCCTATCAGCAGCTGATCTGCGCCGCCTGCGGCATTAAGTACACTTCGCTGGACAATCTGCGCGCGCACCAGAACTACTATTGCCCCAAGGGCGGGGCGGCAGCCACGCCCGCCGAGGCAGCCACACCACAGTTGCCGCTGCCCAAGGAGAAGTGCGTCAAGTGCAAGACGCTGCACGATCACGGCCAGCCGTGTCCAACGcccccagccacgccccagcTGGCGCCTGCCAGTGTGGCTGCGAACAGCGTAAACAAGTGCCCCGTGTGCGGCGTGGTCAGCCCCACCGCTGCGCTGGCCCGCAAGCACATGGAAATGCACGGCACGGTCAAGGCATTCCGCTGCAGCATCTGCCAGTACAAGGGCAACACGCTGCGCGGCATGAGGACCCACATACGCACCCACTTCGATAAGAAGACCAGCGATGTAAACGAGGAGCACTACATGACCTGCATCTTTGAGGAGGatacggcagcagcagctgcagcagccgccgcgcCACCCCCAGCCATGGGGCTGGACCTGCCCGCCGTGACAGCGGCCCAGGAGCAGCTGGAACAGCATGCGGCACAGATCTTCAACTGCGATCACTGCAACTATGCCTCCACCTACAAGGGCAACGTGCTGCGCCACATGAAACTGTTGCATCCACACGTGGCAATCAGCTCGCCCTCCATCTCGCCCGAGTCCCGTGAGCAGGATGCCAATGCCCATGCTCTGCCCGAGGTGGCGCTGGTGAATGGCGAACGCGAAAGCTTTCACATTAAGTCGGAGCCCTTGGAGCCAGCTGTGGCCACGCTGAGTCTTGTGCACGATAACAACAATTCGCCCATTGGCACGCCGCACACGCACATCAAAGCCGAACCACTGGACATGGGCATAGAGTTGACTCCAGCCACACTGCCGCCACCCATAGCCAATTCGCCGCTGGGGCCGAGCGCTGCGGAGGCCATGAAGAAATACTGTTCCACCTGCGATATATCGTTCAACTATGTGAAGACCTTTTTGGCGCACAAGCAGTTCTACTGCAAGAGCAAGCTGCATCGGCCGGAGGCCACTGATAGCCCCAGTCCCACAGTGGGCGTCGGTGGCGCCGCCATGCCGCTGCAGTCGCCCagcgagctgctgttgctgcagaaGAACAAGGAGAATCTGCAggaggcggccatttga
Protein Sequence: MAAYNAHQQQQQQQQQQQQHRQERQQCWPNSKDLGAHELSEEKQQLDELPEDEQLEQHASNASEQLEETDMDQEMVEQEQAAFQEASAQQQDVADSSTTPPRSPTPPELVPKLERADSPATPPSVAATPSPPPTPTPPPALPKLRLNALLASDPALKPDAKELNLEPRLLGPPPQLAKPEQQQQQQQNLPDPSSLVEPLLKPARFMCLPCGIAFSSPSTLEAHQAYYCSHRNKDADEESAAVDKATAAAVGGGGNPNANSSSSGGSSGSEPPAKVARTGKQYACTQCSYSADKKVSLNRHMRMHQTSPAAPTLNSLSGLAANGVVAAAAATAAASALEETSSQQIDRYCSDCDIRFNNIKTYRAHKQHYCSSRRSDGQLTPKPEANASSSTGGSAAGVAAGGAKHSGAHSPQTRNKTPTPAMVAAAAAAAAAAASLQVAPPQPFLALPTNPIIIVPCSLIRAASLIPGPLTTSTSGIVNPESTCFTLDNGALKPLATALNINALAGNATPTPTGTPMPSSNQLSMPVPEPERPSVSNVPETETKSSPPEPKRKEASGMRDTTPLDLSLRRSPISPLLQRQRLMEEALLSVGKENLESSSRTGGSVTPEQIVCAPSLPSSPSMSPSPKRRAISPRSSGAGSAASMSPPALAVPHLLDNLQPLRSMLPGDFALSESLLAKTNPELALKLAAAAAAAVAGSSSSAELASKLGFSPVPSGAAPPPAVGTVAANAPNSQPQIYVKQGVSKCKECNIVFCKYENYLAHKQHYCSARNQDAGVDGDSKNAVTPPAAVGPGVTAGASSLETTPVAYQQLICAACGIKYTSLDNLRAHQNYYCPKGGAAATPAEAATPQLPLPKEKCVKCKTLHDHGQPCPTPPATPQLAPASVAANSVNKCPVCGVVSPTAALARKHMEMHGTVKAFRCSICQYKGNTLRGMRTHIRTHFDKKTSDVNEEHYMTCIFEEDTAAAAAAAAAPPPAMGLDLPAVTAAQEQLEQHAAQIFNCDHCNYASTYKGNVLRHMKLLHPHVAISSPSISPESREQDANAHALPEVALVNGERESFHIKSEPLEPAVATLSLVHDNNNSPIGTPHTHIKAEPLDMGIELTPATLPPPIANSPLGPSAAEAMKKYCSTCDISFNYVKTFLAHKQFYCKSKLHRPEATDSPSPTVGVGGAAMPLQSPSELLLLQKNKENLQEAAI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00598429;
90% Identity: iTF_00532635;
80% Identity: -