Basic Information

Gene Symbol
-
Assembly
GCA_004382145.1
Location
NC:4398366-4399447[-]

Transcription Factor Domain

TF Family
zf-LITAF-like
Domain
zf-LITAF-like domain
PFAM
PF10601
TF Group
Zinc-Coordinating Group
Description
Members of this family display a conserved zinc ribbon structure [3] with the motif C-XX-C- separated from the more C-terminal HX-C(P)X-C-X4-G-R motif by a variable region of usually 25-30 (hydrophobic) residues. Although it belongs to one of the zinc finger's fold groups (zinc ribbon), this particular domain was first identified in LPS-induced tumour necrosis alpha factor (LITAF) which is produced in mammalian cells after being challenged with lipopolysaccharide (LPS)[2]. The hydrophobic region probably inserts into the membrane rather than traversing it. Such an insertion brings together the N- and C-terminal C-XX-C motifs to form a compact Zn2+-binding structure [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 3 0.52 4.5e+02 0.7 2.6 52 67 9 24 5 27 0.77
2 3 3.2 2.8e+03 -1.8 0.8 35 35 101 101 75 120 0.54
3 3 5.6e-08 4.8e-05 23.1 6.1 5 70 149 206 145 206 0.88

Sequence Information

Coding Sequence
ATGTCGAAGCAAAATATTCAGAAAGACCAAGATGAGTGCCTTCGTTGCATGCGCTGCAAGAAAGTGATCCAATGTTCACGTTTCGATAGCGGTAGCTTACTGCGTCACATCGAATATGAGCATCCGGAATTATTCAAGATGGCCCATTCCAaagtcaaaagtatttacaatcCCTCAACGGATAAGAGATCGGATTCGGAACTTGATGCTGAAAGTTTGGGGCGATGTAAGAACAAAAAGAGGACCTCTAGCGATGACATGACCAAAAAATCATCGATTACCAGGTGCAATGTGGCTGCTGCCAACTCTACATGTCCGCACTCAAAAGCCAAGTACAGTAAATGTCCAAAAGCCAAGACCACTGGTCCGTGTTCGCCGCACCACTTGATCTTTCGCAAGATGGCCTACAAGACCTCCGCCAGGCGATGGTGTGCCATGGATGGCAGTATCTTCTGCCCCGCTTGCGGTTATAAGAAGCGTCCAGTGATCAAATGCGCATCGGATTGGAATTCCAGATGGTGTTCATGGGCCCTTTGCTTTATGCCCTGTCTGAATAACTCGGATGATGGGGAGAAGATTTACTGCGGTCACTGTAACACCTTTTTGGGCGTCTACAATCGCCAAAGGCAAAGTCTCAAGCCGAACAAGCTGTATGCCTGA
Protein Sequence
MSKQNIQKDQDECLRCMRCKKVIQCSRFDSGSLLRHIEYEHPELFKMAHSKVKSIYNPSTDKRSDSELDAESLGRCKNKKRTSSDDMTKKSSITRCNVAAANSTCPHSKAKYSKCPKAKTTGPCSPHHLIFRKMAYKTSARRWCAMDGSIFCPACGYKKRPVIKCASDWNSRWCSWALCFMPCLNNSDDGEKIYCGHCNTFLGVYNRQRQSLKPNKLYA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00592770;
90% Identity
-
80% Identity
-